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Volume 99(13);  June 25, 2002
Biochemistry
Zinc finger as distance determinant in the flexible linker of intron endonuclease I-TevI
Amy B. Dean, Matt J. Stanger, John T. Dansereau, Patrick Van Roey, Victoria Derbyshire, and Marlene Belfort
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8554–8561. Published online 2002 June 19. doi: 10.1073/pnas.082253699.
PMCID: PMC124309
Commentaries
Microbial subversion of the immune response
P. J. Lachmann
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8461–8462. Published online 2002 June 19. doi: 10.1073/pnas.132284499.
PMCID: PMC124270
A new type of photoreceptor in algae
Thomas G. Ebrey
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8463–8464. doi: 10.1073/pnas.142293599.
PMCID: PMC124272
Might a vanguard of mRNAs prepare cells for the arrival of herpes simplex virus?
Thomas Shenk
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8465–8466. doi: 10.1073/pnas.152301499.
PMCID: PMC124273
Physical Sciences
Applied Mathematics
The p53MH algorithm and its application in detecting p53-responsive genes
J. Hoh, S. Jin, T. Parrado, J. Edington, A. J. Levine, and J. Ott
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8467–8472. Published online 2002 June 19. doi: 10.1073/pnas.132268899.
PMCID: PMC124275
Structure theorems for game trees
Srihari Govindan and Robert Wilson
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9077–9080. Published online 2002 June 11. doi: 10.1073/pnas.082249599.
PMCID: PMC124887
Applied Physical Sciences
Inverting dynamic force microscopy: From signals to time-resolved interaction forces
Martin Stark, Robert W. Stark, Wolfgang M. Heckl, and Reinhard Guckenberger
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8473–8478. Published online 2002 June 17. doi: 10.1073/pnas.122040599.
PMCID: PMC124277
Design of protein struts for self-assembling nanoconstructs
Paul Hyman, Regina Valluzzi, and Edward Goldberg
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8488–8493. Published online 2002 June 17. doi: 10.1073/pnas.132544299.
PMCID: PMC124284
Chemistry
Liquid–liquid separation in solutions of normal and sickle cell hemoglobin
Oleg Galkin, Kai Chen, Ronald L. Nagel, Rhoda Elison Hirsch, and Peter G. Vekilov
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8479–8483. Published online 2002 June 17. doi: 10.1073/pnas.122055299.
PMCID: PMC124280
Physics
Contactless experiments on individual DNA molecules show no evidence for molecular wire behavior
C. Gómez-Navarro, F. Moreno-Herrero, P. J. de Pablo, J. Colchero, J. Gómez-Herrero, and A. M. Baró
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8484–8487. Published online 2002 June 17. doi: 10.1073/pnas.122610899.
PMCID: PMC124282
Biological Sciences
Applied Biological Sciences
Design of protein struts for self-assembling nanoconstructs
Paul Hyman, Regina Valluzzi, and Edward Goldberg
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8488–8493. Published online 2002 June 17. doi: 10.1073/pnas.132544299.
PMCID: PMC124284
Biochemistry
Omnipotent decoding potential resides in eukaryotic translation termination factor eRF1 of variant-code organisms and is modulated by the interactions of amino acid sequences within domain 1
Koichi Ito, Ludmila Frolova, Alim Seit-Nebi, Andrey Karamyshev, Lev Kisselev, and Yoshikazu Nakamura
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8494–8499. doi: 10.1073/pnas.142690099.
PMCID: PMC124286
From the Cover:
trilogy: Discovery of sequence–structure patterns across diverse proteins
Philip Bradley, Peter S. Kim, and Bonnie Berger
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8500–8505. doi: 10.1073/pnas.112221999.
PMCID: PMC124288
All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade
Joris Messens, José C. Martins, Karolien Van Belle, Elke Brosens, Aline Desmyter, Marjan De Gieter, Jean-Michel Wieruszeski, Rudolph Willem, Lode Wyns, and Ingrid Zegers
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8506–8511. Published online 2002 June 18. doi: 10.1073/pnas.132142799.
PMCID: PMC124290
Identification of a gene encoding MGAT1, a monoacylglycerol acyltransferase
Chi-Liang Eric Yen, Scot J. Stone, Sylvaine Cases, Ping Zhou, and Robert V. Farese, Jr.
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8512–8517. Published online 2002 June 19. doi: 10.1073/pnas.132274899.
PMCID: PMC124292
The rate-limiting step in the folding of a large ribozyme without kinetic traps
X.-W. Fang, P. Thiyagarajan, T. R. Sosnick, and T. Pan
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8518–8523. doi: 10.1073/pnas.142288399.
PMCID: PMC124294
Specificity and affinity motifs for Grb2 SH2-ligand interactions
Helmut W. H. G. Kessels, Alister C. Ward, and Ton N. M. Schumacher
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8524–8529. doi: 10.1073/pnas.142224499.
PMCID: PMC124298
Isolation of receptor–ligand pairs by capture of long-lived multivalent interaction complexes
Ruud M. T. de Wildt, Ian M. Tomlinson, Jennifer L. Ong, and Philipp Holliger
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8530–8535. doi: 10.1073/pnas.132008499.
PMCID: PMC124300
Autoregulation of a bacterial σ factor explored by using segmental isotopic labeling and NMR
Julio A. Camarero, Alexander Shekhtman, Elizabeth A. Campbell, Mark Chlenov, Tanja M. Gruber, Donald A. Bryant, Seth A. Darst, David Cowburn, and Tom W. Muir
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8536–8541. doi: 10.1073/pnas.132033899.
PMCID: PMC124302
Interactions of mutant and wild-type flap endonucleases with oligonucleotide substrates suggest an alternative model of DNA binding
Joe J. Dervan, Min Feng, Dipak Patel, Jane A. Grasby, Peter J. Artymiuk, Thomas A. Ceska, and Jon R. Sayers
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8542–8547. doi: 10.1073/pnas.082241699.
PMCID: PMC124304
Gene activation by interaction of an inhibitor with a cytoplasmic signaling protein
Gang Peng and James E. Hopper
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8548–8553. doi: 10.1073/pnas.142100099.
PMCID: PMC124307
Zinc finger as distance determinant in the flexible linker of intron endonuclease I-TevI
Amy B. Dean, Matt J. Stanger, John T. Dansereau, Patrick Van Roey, Victoria Derbyshire, and Marlene Belfort
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8554–8561. Published online 2002 June 19. doi: 10.1073/pnas.082253699.
PMCID: PMC124309
Kinetic analysis of estrogen receptor/ligand interactions
Rebecca L. Rich, Lise R. Hoth, Kieran F. Geoghegan, Thomas A. Brown, Peter K. LeMotte, Samuel P. Simons, Preston Hensley, and David G. Myszka
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8562–8567. Published online 2002 June 19. doi: 10.1073/pnas.142288199.
PMCID: PMC124311
Sequence determinants of the energetics of folding of a transmembrane four-helix-bundle protein
Kathleen P. Howard, James D. Lear, and William F. DeGrado
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8568–8572. doi: 10.1073/pnas.132266099.
PMCID: PMC124313
Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule
Eckhard Bender, Arjan Buist, Mirek Jurzak, Xavier Langlois, Geert Baggerman, Peter Verhasselt, Martine Ercken, Hong-Qing Guo, Cindy Wintmolders, Ilse Van den Wyngaert, Irma Van Oers, Liliane Schoofs, and Walter Luyten
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8573–8578. doi: 10.1073/pnas.122016499.
PMCID: PMC124315
Ebselen: A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant
Rong Zhao, Hiroyuki Masayasu, and Arne Holmgren
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8579–8584. Published online 2002 June 17. doi: 10.1073/pnas.122061399.
PMCID: PMC124318
Hsp90 enables Ctf13p/Skp1p to nucleate the budding yeast kinetochore
Olaf Stemmann, Anke Neidig, Thomas Köcher, Matthias Wilm, and Johannes Lechner
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8585–8590. doi: 10.1073/pnas.082223899.
PMCID: PMC124320
A target essential for the activity of a nonacidic yeast transcriptional activator
Zhen Lu, Aseem Z. Ansari, Xiangyang Lu, Anuja Ogirala, and Mark Ptashne
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8591–8596. doi: 10.1073/pnas.092263499.
PMCID: PMC124323
Employing Escherichia coli to functionally express, purify, and characterize a human transporter
Matthias Quick and Ernest M. Wright
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8597–8601. Published online 2002 June 19. doi: 10.1073/pnas.132266599.
PMCID: PMC124325
NTP-sensing by rRNA promoters in Escherichia coli is direct
David A. Schneider, Tamas Gaal, and Richard L. Gourse
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8602–8607. Published online 2002 June 11. doi: 10.1073/pnas.132285199.
PMCID: PMC124327
Overexpression, purification, and site-directed spin labeling of the Nramp metal transporter from Mycobacterium leprae
Ian Reeve, David Hummell, Nathan Nelson, and John Voss
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8608–8613. Published online 2002 June 19. doi: 10.1073/pnas.142287699.
PMCID: PMC124330
Biophysics
Specific zinc-finger architecture required for HIV-1 nucleocapsid protein's nucleic acid chaperone function
Mark C. Williams, Robert J. Gorelick, and Karin Musier-Forsyth
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8614–8619. doi: 10.1073/pnas.132128999.
PMCID: PMC124332
How to describe protein motion without amino acid sequence and atomic coordinates
Dengming Ming, Yifei Kong, Maxime A. Lambert, Zhong Huang, and Jianpeng Ma
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8620–8625. doi: 10.1073/pnas.082148899.
PMCID: PMC124334
Using deeply trapped intermediates to map the cytochrome c folding landscape
F. Akif Tezcan, William M. Findley, Brian R. Crane, Scott A. Ross, Julia G. Lyubovitsky, Harry B. Gray, and Jay R. Winkler
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8626–8630. doi: 10.1073/pnas.132254499.
PMCID: PMC124336
A possible evolutionary origin for the Mn4 cluster of the photosynthetic water oxidation complex from natural MnO2 precipitates in the early ocean
Kenneth Sauer and Vittal K. Yachandra
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8631–8636. Published online 2002 June 19. doi: 10.1073/pnas.132266199.
PMCID: PMC124339
Topological determinants of protein folding
Nikolay V. Dokholyan, Lewyn Li, Feng Ding, and Eugene I. Shakhnovich
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8637–8641. doi: 10.1073/pnas.122076099.
PMCID: PMC124342
Hidden Markov models from molecular dynamics simulations on DNA
Kelly M. Thayer and D. L. Beveridge
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8642–8647. Published online 2002 June 18. doi: 10.1073/pnas.132148699.
PMCID: PMC124344
Probing solvent accessibility of amyloid fibrils by solution NMR spectroscopy
Johannes H. Ippel, Anders Olofsson, Jürgen Schleucher, Erik Lundgren, and Sybren S. Wijmenga
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8648–8653. Published online 2002 June 18. doi: 10.1073/pnas.132098999.
PMCID: PMC124346
Tuning the membrane surface potential for efficient toxin import
Stanislav D. Zakharov, Tatyana I. Rokitskaya, Vladimir L. Shapovalov, Yuri N. Antonenko, and William A. Cramer
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8654–8659. Published online 2002 June 11. doi: 10.1073/pnas.122613099.
PMCID: PMC124348
Cell Biology
The p53MH algorithm and its application in detecting p53-responsive genes
J. Hoh, S. Jin, T. Parrado, J. Edington, A. J. Levine, and J. Ott
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8467–8472. Published online 2002 June 19. doi: 10.1073/pnas.132268899.
PMCID: PMC124275
Dome formation in cell cultures as expression of an early stage of lactogenic differentiation of the mammary gland
I. Zucchi, L. Bini, D. Albani, R. Valaperta, S. Liberatori, R. Raggiaschi, C. Montagna, L. Susani, O. Barbieri, V. Pallini, P. Vezzoni, and R. Dulbecco
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8660–8665. Published online 2002 June 19. doi: 10.1073/pnas.132259399.
PMCID: PMC124351
Presenilin and nicastrin regulate each other and determine amyloid β-peptide production via complex formation
Dieter Edbauer, Edith Winkler, Christian Haass, and Harald Steiner
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8666–8671. Published online 2002 June 4. doi: 10.1073/pnas.132277899.
PMCID: PMC124353
Activation of Cdc2/cyclin B and inhibition of centrosome amplification in cells depleted of Plk1 by siRNA
Xiaoqi Liu and Raymond L. Erikson
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8672–8676. Published online 2002 June 19. doi: 10.1073/pnas.132269599.
PMCID: PMC124355
An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cells
Lisa L. Hall, Meg Byron, Kosuke Sakai, Laura Carrel, Huntington F. Willard, and Jeanne B. Lawrence
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8677–8682. Published online 2002 June 18. doi: 10.1073/pnas.132468999.
PMCID: PMC124357
Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon
Christine B. Anderson, Kristi L. Neufeld, and Raymond L. White
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8683–8688. Published online 2002 June 18. doi: 10.1073/pnas.122235399.
PMCID: PMC124359
From the Cover:
Two rhodopsins mediate phototaxis to low- and high-intensity light in Chlamydomonas reinhardtii
Oleg A. Sineshchekov, Kwang-Hwan Jung, and John L. Spudich
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8689–8694. Published online 2002 June 11. doi: 10.1073/pnas.122243399.
PMCID: PMC124360
Methylation of histone H3 Lys 4 in coding regions of active genes
Bradley E. Bernstein, Emily L. Humphrey, Rachel L. Erlich, Robert Schneider, Peter Bouman, Jun S. Liu, Tony Kouzarides, and Stuart L. Schreiber
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8695–8700. Published online 2002 June 11. doi: 10.1073/pnas.082249499.
PMCID: PMC124361
Evidence that subcellular localization of a bacterial membrane protein is achieved by diffusion and capture
David Z. Rudner, Qi Pan, and Richard M. Losick
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8701–8706. Published online 2002 June 11. doi: 10.1073/pnas.132235899.
PMCID: PMC124362
Developmental Biology
Previously uncharacterized histone acetyltransferases implicated in mammalian spermatogenesis
Bruce T. Lahn, Zhao Lan Tang, Jianxin Zhou, Robert J. Barndt, Martti Parvinen, C. David Allis, and David C. Page
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8707–8712. Published online 2002 June 18. doi: 10.1073/pnas.082248899.
PMCID: PMC124363
From the Cover:
Bone patterning is altered in the regenerating zebrafish caudal fin after ectopic expression of sonic hedgehog and bmp2b or exposure to cyclopamine
Elizabeth Quint, Amanda Smith, Fabien Avaron, Lynda Laforest, Jennifer Miles, William Gaffield, and Marie-Andrée Akimenko
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8713–8718. Published online 2002 June 11. doi: 10.1073/pnas.122571799.
PMCID: PMC124364
Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype
Guy Goudreau, Petros Petrou, Lixing W. Reneker, Jochen Graw, Jana Löster, and Peter Gruss
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8719–8724. Published online 2002 June 18. doi: 10.1073/pnas.132195699.
PMCID: PMC124365
Ecology
From the Cover:
The etiology of white pox, a lethal disease of the Caribbean elkhorn coral, Acropora palmata
Kathryn L. Patterson, James W. Porter, Kim B. Ritchie, Shawn W. Polson, Erich Mueller, Esther C. Peters, Deborah L. Santavy, and Garriet W. Smith
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8725–8730. Published online 2002 June 19. doi: 10.1073/pnas.092260099.
PMCID: PMC124366
Increased competition may promote species coexistence
J. Vandermeer, M. A. Evans, P. Foster, T. Höök, M. Reiskind, and M. Wund
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8731–8736. Published online 2002 June 17. doi: 10.1073/pnas.142073599.
PMCID: PMC124367
Evolution
SOS-induced DNA polymerases enhance long-term survival and evolutionary fitness
Bethany Yeiser, Evan D. Pepper, Myron F. Goodman, and Steven E. Finkel
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8737–8741. Published online 2002 June 11. doi: 10.1073/pnas.092269199.
PMCID: PMC124368
On the evolution of cells
Carl R. Woese
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8742–8747. Published online 2002 June 19. doi: 10.1073/pnas.132266999.
PMCID: PMC124369
Microsatellite evolution inferred from human– chimpanzee genomic sequence alignments
Matthew T. Webster, Nick G. C. Smith, and Hans Ellegren
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8748–8753. Published online 2002 June 17. doi: 10.1073/pnas.122067599.
PMCID: PMC124370
Quantitative evolutionary design of nutrient processing: Glucose
Anthony C. Steyermark, Mandy M. Lam, and Jared Diamond
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8754–8759. Published online 2002 June 19. doi: 10.1073/pnas.132277799.
PMCID: PMC124371
Genetics
The aspartate-257 of presenilin 1 is indispensable for mouse development and production of β-amyloid peptides through β-catenin-independent mechanisms
Xuefeng Xia, Pei Wang, Xiaoyan Sun, Salvador Soriano, Wan-Kyng Shum, Haruyasu Yamaguchi, Myrna E. Trumbauer, Akihiko Takashima, Edward H. Koo, and Hui Zheng
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8760–8765. Published online 2002 June 17. doi: 10.1073/pnas.132045399.
PMCID: PMC124372
TRAF6-deficient mice display hypohidrotic ectodermal dysplasia
Asuka Naito, Hisahiro Yoshida, Eri Nishioka, Mizuho Satoh, Sakura Azuma, Tadashi Yamamoto, Shin-ichi Nishikawa, and Jun-ichiro Inoue
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8766–8771. Published online 2002 June 11. doi: 10.1073/pnas.132636999.
PMCID: PMC124373
Short inverted repeats initiate gene amplification through the formation of a large DNA palindrome in mammalian cells
Hisashi Tanaka, Stephen J. Tapscott, Barbara J. Trask, and Meng-Chao Yao
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8772–8777. Published online 2002 June 11. doi: 10.1073/pnas.132275999.
PMCID: PMC124374
Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents
Geoff W. Birrell, James A. Brown, H. Irene Wu, Guri Giaever, Angela M. Chu, Ronald W. Davis, and J. Martin Brown
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8778–8783. Published online 2002 June 19. doi: 10.1073/pnas.132275199.
PMCID: PMC124375
Polynucleotide phosphorylase is a global regulator of virulence and persistency in Salmonella enterica
Mark O. Clements, Sofia Eriksson, Arthur Thompson, Sacha Lucchini, Jay C. D. Hinton, Staffan Normark, and Mikael Rhen
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8784–8789. Published online 2002 June 18. doi: 10.1073/pnas.132047099.
PMCID: PMC124376
Binding sites of different geometries for the 16-3 phage repressor
Péter P. Papp, Tibor Nagy, Szilamér Ferenczi, Péter Élõ, Zsolt Csiszovszki, Zsuzsanna Buzás, András Patthy, and László Orosz
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8790–8795. doi: 10.1073/pnas.132275399.
PMCID: PMC124377
Transcriptional collision between convergent genes in budding yeast
Elizabeth M. Prescott and Nick J. Proudfoot
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8796–8801. Published online 2002 June 19. doi: 10.1073/pnas.132270899.
PMCID: PMC124378
A cytosine methyltransferase homologue is essential for repeat-induced point mutation in Neurospora crassa
Michael Freitag, Rebecca L. Williams, Gregory O. Kothe, and Eric U. Selker
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8802–8807. Published online 2002 June 18. doi: 10.1073/pnas.132212899.
PMCID: PMC124379
Immunology
From the Cover:
Variola virus immune evasion design: Expression of a highly efficient inhibitor of human complement
Ariella M. Rosengard, Yu Liu, Zhiping Nie, and Robert Jimenez
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8808–8813. Published online 2002 May 28. doi: 10.1073/pnas.112220499.
PMCID: PMC124380
Genome expression analysis of Anopheles gambiae: Responses to injury, bacterial challenge, and malaria infection
George Dimopoulos, George K. Christophides, Stephan Meister, Jörg Schultz, Kevin P. White, Carolina Barillas-Mury, and Fotis C. Kafatos
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8814–8819. Published online 2002 June 19. doi: 10.1073/pnas.092274999.
PMCID: PMC124381
Alternate interactions define the binding of peptides to the MHC molecule IAb
Xinqi Liu, Shaodong Dai, Frances Crawford, Rachel Frugé, Philippa Marrack, and John Kappler
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8820–8825. doi: 10.1073/pnas.132272099.
PMCID: PMC124382
Recognition of a virus-encoded ligand by a natural killer cell activation receptor
Hamish R. C. Smith, Jonathan W. Heusel, Indira K. Mehta, Sungjin Kim, Brigitte G. Dorner, Olga V. Naidenko, Koho Iizuka, Hiroshi Furukawa, Diana L. Beckman, Jeanette T. Pingel, Anthony A. Scalzo, Daved H. Fremont, and Wayne M. Yokoyama
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8826–8831. Published online 2002 June 11. doi: 10.1073/pnas.092258599.
PMCID: PMC124383
CD25+CD4+ T cells contribute to the control of memory CD8+ T cells
Masaaki Murakami, Akemi Sakamoto, Jeremy Bender, John Kappler, and Philippa Marrack
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8832–8837. doi: 10.1073/pnas.132254399.
PMCID: PMC124384
Identification of gene function by cyclical packaging rescue of retroviral cDNA libraries
Deepta Bhattacharya, Eric C. Logue, Sonia Bakkour, James DeGregori, and William C. Sha
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8838–8843. doi: 10.1073/pnas.132274799.
PMCID: PMC124385
Distinct recognition by two subsets of T cells of an MHC class II-peptide complex
Zheng Pu, Javier A. Carrero, and Emil R. Unanue
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8844–8849. doi: 10.1073/pnas.092260499.
PMCID: PMC124386
MHC class I-dependent Vγ4+ pulmonary T cells regulate αβ T cell-independent airway responsiveness
Michael Lahn, Arihiko Kanehiro, Katsuyuki Takeda, Jennifer Terry, Youn-Soo Hahn, M. Kemal Aydintug, Anatole Konowal, Koichi Ikuta, Rebecca L. O'Brien, Erwin W. Gelfand, and Willi K. Born
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8850–8855. Published online 2002 June 17. doi: 10.1073/pnas.132519299.
PMCID: PMC124387
The myelin basic protein gene is expressed in differentiated blood cell lineages and in hemopoietic progenitors
M. C. Marty, F. Alliot, J. Rutin, R. Fritz, D. Trisler, and B. Pessac
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8856–8861. doi: 10.1073/pnas.122079599.
PMCID: PMC124388
Urokinase–urokinase receptor interaction mediates an inhibitory signal for HIV-1 replication
Massimo Alfano, Nicolai Sidenius, Barbara Panzeri, Francesco Blasi, and Guido Poli
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8862–8867. doi: 10.1073/pnas.142078099.
PMCID: PMC124389
Medical Sciences
Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2-induced lymphangiogenesis in mouse cornea
Hajime Kubo, Renhai Cao, Ebba Bräkenhielm, Taija Mäkinen, Yihai Cao, and Kari Alitalo
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8868–8873. Published online 2002 June 17. doi: 10.1073/pnas.062040199.
PMCID: PMC124390
Stable expression of calpain 3 from a muscle transgene in vivo: Immature muscle in transgenic mice suggests a role for calpain 3 in muscle maturation
M. J. Spencer, J. R. Guyon, H. Sorimachi, A. Potts, I. Richard, M. Herasse, J. Chamberlain, I. Dalkilic, L. M. Kunkel, and J. S. Beckmann
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8874–8879. Published online 2002 June 19. doi: 10.1073/pnas.132269299.
PMCID: PMC124391
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy
Cemil Özcelik, Bettina Erdmann, Bernhard Pilz, Nina Wettschureck, Stefan Britsch, Norbert Hübner, Kenneth R. Chien, Carmen Birchmeier, and Alistair N. Garratt
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8880–8885. Published online 2002 June 18. doi: 10.1073/pnas.122249299.
PMCID: PMC124392
Transformation of follicular lymphoma to diffuse large-cell lymphoma: Alternative patterns with increased or decreased expression of c-myc and its regulated genes
Izidore S. Lossos, Ash A. Alizadeh, Maximilian Diehn, Roger Warnke, Yvonne Thorstenson, Peter J. Oefner, Patrick O. Brown, David Botstein, and Ronald Levy
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8886–8891. Published online 2002 June 19. doi: 10.1073/pnas.132253599.
PMCID: PMC124393
Inhibition of mitochondrial respiration by endogenous nitric oxide: A critical step in Fas signaling
Belén Beltrán, Marisol Quintero, Eugenia García-Zaragozá, Enrique O'Connor, Juan V. Esplugues, and Salvador Moncada
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8892–8897. Published online 2002 June 19. doi: 10.1073/pnas.092259799.
PMCID: PMC124394
In vivo properties of an anti-GnRH Spiegelmer: An example of an oligonucleotide-based therapeutic substance class
Britta Wlotzka, Susanne Leva, Bernd Eschgfäller, Jens Burmeister, Frank Kleinjung, Christine Kaduk, Peter Muhn, Holger Hess-Stumpp, and Sven Klussmann
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8898–8902. Published online 2002 June 17. doi: 10.1073/pnas.132067399.
PMCID: PMC124395
Role of Lkb1, the causative gene of Peutz–Jegher's syndrome, in embryogenesis and polyposis
Kou-ichi Jishage, Jun-ichi Nezu, Yosuke Kawase, Takamitsu Iwata, Miho Watanabe, Akio Miyoshi, Asuka Ose, Kiyoshi Habu, Takei Kake, Nobuo Kamada, Otoya Ueda, Michiko Kinoshita, Dieter E. Jenne, Miyuki Shimane, and Hiroshi Suzuki
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8903–8908. Published online 2002 June 11. doi: 10.1073/pnas.122254599.
PMCID: PMC124396
Adeno-associated virus type-2 expression of pigmented epithelium-derived factor or Kringles 1–3 of angiostatin reduce retinal neovascularization
Brian J. Raisler, Kenneth I. Berns, Maria B. Grant, Denis Beliaev, and William W. Hauswirth
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8909–8914. Published online 2002 June 18. doi: 10.1073/pnas.122247299.
PMCID: PMC124397
Bucillamine, a thiol antioxidant, prevents transplantation-associated reperfusion injury
Farin Amersi, Sally K. Nelson, Xiu Da Shen, Hirohisa Kato, Judy Melinek, Jerzy W. Kupiec-Weglinski, Lawrence D. Horwitz, Ronald W. Busuttil, and Marcus A. Horwitz
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8915–8920. doi: 10.1073/pnas.132026099.
PMCID: PMC124398
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression
Kazuhiro Ito, Sam Lim, Gaetano Caramori, Borja Cosio, K. Fan Chung, Ian M. Adcock, and Peter J. Barnes
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8921–8926. Published online 2002 June 17. doi: 10.1073/pnas.132556899.
PMCID: PMC124399
Intestinal adenomas can develop with a stable karyotype and stable microsatellites
Kevin M. Haigis, James G. Caya, Mark Reichelderfer, and William F. Dove
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8927–8931. Published online 2002 June 11. doi: 10.1073/pnas.132275099.
PMCID: PMC124400
Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone
Edwin M. Horwitz, Patricia L. Gordon, Winston K. K. Koo, Jeffrey C. Marx, Michael D. Neel, Rene Y. McNall, Linda Muul, and Ted Hofmann
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8932–8937. doi: 10.1073/pnas.132252399.
PMCID: PMC124401
Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice
Amanda Sainsbury, Christoph Schwarzer, Michelle Couzens, Serguei Fetissov, Sabine Furtinger, Arthur Jenkins, Helen M. Cox, Günther Sperk, Tomas Hökfelt, and Herbert Herzog
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8938–8943. Published online 2002 June 18. doi: 10.1073/pnas.132043299.
PMCID: PMC124402
Microbiology
DNA containing CpG motifs induces angiogenesis
Mei Zheng, Dennis M. Klinman, Malgorzata Gierynska, and Barry T. Rouse
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8944–8949. Published online 2002 June 11. doi: 10.1073/pnas.132605599.
PMCID: PMC124403
Emergence of multiple genotypes of H5N1 avian influenza viruses in Hong Kong SAR
Y. Guan, J. S. M. Peiris, A. S. Lipatov, T. M. Ellis, K. C. Dyrting, S. Krauss, L. J. Zhang, R. G. Webster, and K. F. Shortridge
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8950–8955. Published online 2002 June 19. doi: 10.1073/pnas.132268999.
PMCID: PMC124404
Evolutionary genomics of Salmonella: Gene acquisitions revealed by microarray analysis
Steffen Porwollik, Rita Mei-Yi Wong, and Michael McClelland
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8956–8961. Published online 2002 June 18. doi: 10.1073/pnas.122153699.
PMCID: PMC124405
Assembling the glycopeptide antibiotic scaffold: The biosynthesis of from Streptomyces toyocaensis NRRL15009
Jeff Pootoolal, Michael G. Thomas, C. Gary Marshall, John M. Neu, Brian K. Hubbard, Christopher T. Walsh, and Gerard D. Wright
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8962–8967. Published online 2002 June 11. doi: 10.1073/pnas.102285099.
PMCID: PMC124406
Neurobiology
Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice
Michael K. Lee, Wanda Stirling, Yanqun Xu, Xueying Xu, Dike Qui, Allen S. Mandir, Ted M. Dawson, Neal G. Copeland, Nancy A. Jenkins, and Don L. Price
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8968–8973. doi: 10.1073/pnas.132197599.
PMCID: PMC124407
Computational subunits of visual cortical neurons revealed by artificial neural networks
Brian Lau, Garrett B. Stanley, and Yang Dan
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8974–8979. Published online 2002 June 11. doi: 10.1073/pnas.122173799.
PMCID: PMC124408
Trace fear conditioning involves hippocampal α5 GABAA receptors
F. Crestani, R. Keist, J.-M. Fritschy, D. Benke, K. Vogt, L. Prut, H. Blüthmann, H. Möhler, and U. Rudolph
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8980–8985. doi: 10.1073/pnas.142288699.
PMCID: PMC124409
Altered accumbens neural response to prediction of reward associated with place in dopamine D2 receptor knockout mice
Anh Hai Tran, Ryoi Tamura, Teruko Uwano, Tsuneyuki Kobayashi, Motoya Katsuki, Gen Matsumoto, and Taketoshi Ono
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8986–8991. doi: 10.1073/pnas.132284599.
PMCID: PMC124410
A role for ASIC3 in the modulation of high-intensity pain stimuli
Chih-Cheng Chen, Anne Zimmer, Wei-Hsin Sun, Jennifer Hall, Michael J. Brownstein, and Andreas Zimmer
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8992–8997. Published online 2002 June 11. doi: 10.1073/pnas.122245999.
PMCID: PMC124411
Deciphering peripheral nerve myelination by using Schwann cell expression profiling
Rakesh Nagarajan, Nam Le, Heather Mahoney, Toshiyuki Araki, and Jeffrey Milbrandt
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 8998–9003. doi: 10.1073/pnas.132080999.
PMCID: PMC124412
Local circuit neurons in the striatum regulate neural and behavioral responses to dopaminergic stimulation
E. Saka, M. Iadarola, D. J. Fitzgerald, and A. M. Graybiel
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9004–9009. Published online 2002 June 11. doi: 10.1073/pnas.132212499.
PMCID: PMC124413
Amyotrophic lateral sclerosis: A proposed mechanism
Ayako Okado-Matsumoto and Irwin Fridovich
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9010–9014. Published online 2002 June 11. doi: 10.1073/pnas.132260399.
PMCID: PMC124414
Leukemia inhibitory factor inhibits neuronal terminal differentiation through STAT3 activation
Cheil Moon, Joo-Yeon Yoo, Valéry Matarazzo, Young Kwan Sung, Esther J. Kim, and Gabriele V. Ronnett
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9015–9020. doi: 10.1073/pnas.132131699.
PMCID: PMC124415
Time-critical integration of formants for perception of communication calls in mice
Diana B. Geissler and Günter Ehret
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9021–9025. Published online 2002 June 17. doi: 10.1073/pnas.122606499.
PMCID: PMC124416
Cocaine sensitization and reward are under the influence of circadian genes and rhythm
Carolina Abarca, Urs Albrecht, and Rainer Spanagel
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9026–9030. doi: 10.1073/pnas.142039099.
PMCID: PMC124417
Inosine induces axonal rewiring and improves behavioral outcome after stroke
Peng Chen, David E. Goldberg, Bryan Kolb, Marc Lanser, and Larry I. Benowitz
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9031–9036. doi: 10.1073/pnas.132076299.
PMCID: PMC124418
Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming
Frederique Varoqueaux, Albrecht Sigler, Jeong-Seop Rhee, Nils Brose, Carsten Enk, Kerstin Reim, and Christian Rosenmund
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9037–9042. Published online 2002 June 17. doi: 10.1073/pnas.122623799.
PMCID: PMC124419
Plant Biology
Semidwarf (sd-1), “green revolution” rice, contains a defective gibberellin 20-oxidase gene
Wolfgang Spielmeyer, Marc H. Ellis, and Peter M. Chandler
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9043–9048. Published online 2002 June 19. doi: 10.1073/pnas.132266399.
PMCID: PMC124420
Two immediate-early pathogen-responsive members of the AtCMPG gene family in Arabidopsis thaliana and the W-box-containing elicitor-response element of AtCMPG1
Andreas Heise, Bernadette Lippok, Christoph Kirsch, and Klaus Hahlbrock
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9049–9054. doi: 10.1073/pnas.132277699.
PMCID: PMC124421
Suppression and acceleration of cell elongation by integration of xyloglucans in pea stem segments
Takumi Takeda, Yuzo Furuta, Tatsuya Awano, Koichi Mizuno, Yasushi Mitsuishi, and Takahisa Hayashi
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9055–9060. doi: 10.1073/pnas.132080299.
PMCID: PMC124422
Reconstitution in yeast of the Arabidopsis SOS signaling pathway for Na+ homeostasis
Francisco J. Quintero, Masaru Ohta, Huazhong Shi, Jian-Kang Zhu, and Jose M. Pardo
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9061–9066. Published online 2002 June 17. doi: 10.1073/pnas.132092099.
PMCID: PMC124423
Population Biology
Disease surveillance in recombining pathogens: Multilocus genotypes identify sources of human Coccidioides infections
Matthew C. Fisher, Bruce Rannala, Vishnu Chaturvedi, and John W. Taylor
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9067–9071. doi: 10.1073/pnas.132178099.
PMCID: PMC124424
Psychology
Early experience is associated with the development of categorical representations for facial expressions of emotion
Seth D. Pollak and Doris J. Kistler
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9072–9076. Published online 2002 June 18. doi: 10.1073/pnas.142165999.
PMCID: PMC124425
Social Sciences
Economic Sciences
Structure theorems for game trees
Srihari Govindan and Robert Wilson
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9077–9080. Published online 2002 June 11. doi: 10.1073/pnas.082249599.
PMCID: PMC124887
Corrections
Correction
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9081. Published online 2002 June 11. doi: 10.1073/pnas.132227099.
PMCID: PMC124261
Corrects: Eugene W. Myers, et al. On the sequencing and assembly of the human genome. Proc Natl Acad Sci U S A. 2002 April 2; 99(7): 4145–4146.
Correction
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9081. doi: 10.1073/pnas.132249099.
PMCID: PMC124263
Corrects: Andrea G. Cochran, et al. Tryptophan zippers: Stable, monomeric β-hairpins. Proc Natl Acad Sci U S A. 2001 May 8; 98(10): 5578–5583.
Correction
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9081. Published online 2002 June 11. doi: 10.1073/pnas.132280599.
PMCID: PMC124264
Corrects: Shinya Inoué, et al. Fluorescence polarization of green fluorescence protein. Proc Natl Acad Sci U S A. 2002 April 2; 99(7): 4272–4277.
Correction
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9081. Published online 2002 June 11. doi: 10.1073/pnas.122187999.
PMCID: PMC124266
Corrects: Helen R. Moinova, et al. HLTF gene silencing in human colon cancer. Proc Natl Acad Sci U S A. 2002 April 2; 99(7): 4562–4567.
Correction
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9081. doi: 10.1073/pnas.122187899.
PMCID: PMC124267
Corrects: Cristine Alves da Costa, et al. Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons. Proc Natl Acad Sci U S A. 2002 March 19; 99(6): 4043–4048.
Correction
Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9081. Published online 2002 June 11. doi: 10.1073/pnas.132281199.
PMCID: PMC124269
Corrects: Cristina R. Artalejo, et al. Sustained stimulation shifts the mechanism of endocytosis from dynamin-1-dependent rapid endocytosis to clathrin- and dynamin-2-mediated slow endocytosis in chromaffin cells. Proc Natl Acad Sci U S A. 2002 April 30; 99(9): 6358–6363.
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