| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5637–5638. doi: 10.1073/iti1605102.PMCID: PMC556305 Commentaries Viral trafficking violations in axons: The herpesvirus case Urs F. Greber Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5639–5640. Published online 2005 April 12. doi: 10.1073/pnas.0501696102.PMCID: PMC556310 A glimpse at the organization of the protein universe Michele Vendruscolo and Christopher M. Dobson Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5641–5642. Published online 2005 April 12. doi: 10.1073/pnas.0500274102.PMCID: PMC556289 Organization of synaptic myonuclei by Syne proteins and their role during the formation of the nerve–muscle synapse Markus A. Ruegg Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5643–5644. Published online 2005 April 12. doi: 10.1073/pnas.0501516102.PMCID: PMC556304 Coupling neurotrophins to cell migration through selective guanine nucleotide exchange factor activation Barbara L. Hempstead Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5645–5646. Published online 2005 April 12. doi: 10.1073/pnas.0501718102.PMCID: PMC556311 Physical Sciences Applied Mathematics Structure theorems and the dynamics of nitrogen catabolite repression in yeast Erik M. Boczko, Terrance G. Cooper, Tomas Gedeon, Konstantin Mischaikow, Deborah G. Murdock, Siddharth Pratap, and K. Sam Wells Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5647–5652. Published online 2005 April 6. doi: 10.1073/pnas.0501339102.PMCID: PMC556013 Applied Physical Sciences Electrical addressing of confined quantum systems for quasiclassical computation and finite state logic machines F. Remacle, J. R. Heath, and R. D. Levine Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5653–5658. Published online 2005 April 8. doi: 10.1073/pnas.0501623102.PMCID: PMC556307 Chemistry From the Cover: A fullerene molecular tip can detect localized and rectified electron tunneling within a single fullerene–porphyrin pair Tomoaki Nishino, Takashi Ito, and Yoshio Umezawa Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5659–5662. Published online 2005 April 4. doi: 10.1073/pnas.0408474102.PMCID: PMC556290 Mathematics Generalizations of the classical Weyl and Colin de Verdière's formulas and the orbit method Mitya Boyarchenko and Sergei Levendorskii Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5663–5668. Published online 2005 April 12. doi: 10.1073/pnas.0500444102.PMCID: PMC556293 Physics Exact solution of a jamming transition: Closed equations for a bootstrap percolation problem Paolo De Gregorio, Aonghus Lawlor, Phil Bradley, and Kenneth A. Dawson Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5669–5673. Published online 2005 April 4. doi: 10.1073/pnas.0408756102.PMCID: PMC556280 Biological Sciences Anthropology An Early Pleistocene hominin mandible from Atapuerca-TD6, Spain E. Carbonell, J. M. Bermúdez de Castro, J. L. Arsuaga, E. Allue, M. Bastir, A. Benito, I. Cáceres, T. Canals, J. C. Díez, J. van der Made, M. Mosquera, A. Ollé, A. Pérez-González, J. Rodríguez, X. P. Rodríguez, A. Rosas, J. Rosell, R. Sala, J. Vallverdú, and J. M. Vergés Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5674–5678. Published online 2005 April 11. doi: 10.1073/pnas.0501841102.PMCID: PMC556125 Applied Biological Sciences Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung Mini Thomas, James J. Lu, Qing Ge, Chengcheng Zhang, Jianzhu Chen, and Alexander M. Klibanov Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5679–5684. Published online 2005 April 11. doi: 10.1073/pnas.0502067102.PMCID: PMC556302 Biochemistry The nucleotide switch in Cdc42 modulates coupling between the GTPase-binding and allosteric equilibria of Wiskott–Aldrich syndrome protein Daisy W. Leung and Michael K. Rosen Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5685–5690. Published online 2005 April 8. doi: 10.1073/pnas.0406472102.PMCID: PMC556282 Directed evolution of specific receptor–ligand pairs for use in the creation of gene switches Karuppiah Chockalingam, Zhilei Chen, John A. Katzenellenbogen, and Huimin Zhao Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5691–5696. Published online 2005 April 5. doi: 10.1073/pnas.0409206102.PMCID: PMC556283 Linker histone variants control chromatin dynamics during early embryogenesis Hideaki Saeki, Keita Ohsumi, Hitoshi Aihara, Takashi Ito, Susumu Hirose, Kiyoe Ura, and Yasufumi Kaneda Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5697–5702. Published online 2005 April 8. doi: 10.1073/pnas.0409824102.PMCID: PMC556016 Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability Alexandra Beilina, Marcel Van Der Brug, Rili Ahmad, Sashi Kesavapany, David W. Miller, Gregory A. Petsko, and Mark R. Cookson Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5703–5708. Published online 2005 April 11. doi: 10.1073/pnas.0500617102.PMCID: PMC556294 Hemoglobin conformation couples erythrocyte S-nitrosothiol content to O2 gradients Allan Doctor, Ruth Platt, Mary Lynn Sheram, Anne Eischeid, Timothy McMahon, Thomas Maxey, Joseph Doherty, Mark Axelrod, Jaclyn Kline, Matthew Gurka, Andrew Gow, and Benjamin Gaston Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5709–5714. Published online 2005 April 11. doi: 10.1073/pnas.0407490102.PMCID: PMC556285 Biophysics Observing spontaneous branch migration of Holliday junctions one step at a time Sean A. McKinney, Alasdair D. J. Freeman, David M. J. Lilley, and Taekjip Ha Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5715–5720. Published online 2005 April 11. doi: 10.1073/pnas.0409328102.PMCID: PMC556122 Local and long-range stability in tandemly arrayed tetratricopeptide repeats Ewan R. G. Main, Katherine Stott, Sophie E. Jackson, and Lynne Regan Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5721–5726. Published online 2005 April 11. doi: 10.1073/pnas.0404530102.PMCID: PMC556279 Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence Hongtao Zhao, Joy Joseph, Henry M. Fales, Edward A. Sokoloski, Rodney L. Levine, Jeannette Vasquez-Vivar, and B. Kalyanaraman Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5727–5732. Published online 2005 April 11. doi: 10.1073/pnas.0501719102.PMCID: PMC556312 Cell Biology Uncoupling of the functions of the Arabidopsis VIP1 protein in transient and stable plant genetic transformation by Agrobacterium Jianxiong Li, Alexander Krichevsky, Manjusha Vaidya, Tzvi Tzfira, and Vitaly Citovsky Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5733–5738. Published online 2005 April 11. doi: 10.1073/pnas.0404118102.PMCID: PMC556277 Two essential but distinct functions of the mammalian abasic endonuclease Tadahide Izumi, David B. Brown, C. V. Naidu, Kishor K. Bhakat, Mark A. MacInnes, Hiroshi Saito, David J. Chen, and Sankar Mitra Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5739–5743. Published online 2005 April 11. doi: 10.1073/pnas.0500986102.PMCID: PMC556297 Developmental Biology From the Cover: CcbP, a calcium-binding protein from Anabaena sp. PCC 7120, provides evidence that calcium ions regulate heterocyst differentiation Yinhong Zhao, Yunming Shi, Weixing Zhao, Xu Huang, Donghui Wang, Neil Brown, Jerry Brand, and Jindong Zhao Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5744–5748. Published online 2005 April 5. doi: 10.1073/pnas.0501782102.PMCID: PMC556313 Reverse recruitment: The Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation Balaraj B. Menon, Nayan J. Sarma, Satish Pasula, Stephen J. Deminoff, Kristine A. Willis, Kellie E. Barbara, Brenda Andrews, and George M. Santangelo Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5749–5754. Published online 2005 April 7. doi: 10.1073/pnas.0501768102.PMCID: PMC556015 Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility Juxiang Yang, Sergey Medvedev, Junying Yu, Linda C. Tang, Julio E. Agno, Martin M. Matzuk, Richard M. Schultz, and Norman B. Hecht Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5755–5760. Published online 2005 April 11. doi: 10.1073/pnas.0408718102.PMCID: PMC556278 Ecology Evolutionary emergence of size-structured food webs Nicolas Loeuille and Michel Loreau Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5761–5766. Published online 2005 April 11. doi: 10.1073/pnas.0408424102.PMCID: PMC556288 Evolution Dramatic variation of the vomeronasal pheromone receptor gene repertoire among five orders of placental and marsupial mammals Wendy E. Grus, Peng Shi, Ya-ping Zhang, and Jianzhi Zhang Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5767–5772. Published online 2005 March 24. doi: 10.1073/pnas.0501589102.PMCID: PMC556306 Rates of intron loss and gain: Implications for early eukaryotic evolution Scott William Roy and Walter Gilbert Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5773–5778. doi: 10.1073/pnas.0500383102.PMCID: PMC556292 Heterotopic expression of MPF2 is the key to the evolution of the Chinese lantern of Physalis, a morphological novelty in Solanaceae Chaoying He and Heinz Saedler Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5779–5784. Published online 2005 April 11. doi: 10.1073/pnas.0501877102.PMCID: PMC556287 Comparative evolutionary genetics of spontaneous mutations affecting fitness in rhabditid nematodes Charles F. Baer, Frank Shaw, Catherine Steding, Margaret Baumgartner, Alicia Hawkins, Andrew Houppert, Nicole Mason, Marissa Reed, Kevin Simonelic, Wayne Woodard, and Michael Lynch Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5785–5790. Published online 2005 April 4. doi: 10.1073/pnas.0406056102.PMCID: PMC556281 Evolution and development of facial bone morphology in threespine sticklebacks Charles B. Kimmel, Bonnie Ullmann, Charline Walker, Catherine Wilson, Mark Currey, Patrick C. Phillips, Michael A. Bell, John H. Postlethwait, and William A. Cresko Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5791–5796. Published online 2005 April 11. doi: 10.1073/pnas.0408533102.PMCID: PMC556121 Genetics A checkpoint control linking meiotic S phase and recombination initiation in fission yeast Yuko Tonami, Hiroshi Murakami, Katsuhiko Shirahige, and Makoto Nakanishi Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5797–5801. Published online 2005 April 1. doi: 10.1073/pnas.0407236102.PMCID: PMC556284 A population-epigenetic model to infer site-specific methylation rates from double-stranded DNA methylation patterns Diane P. Genereux, Brooks E. Miner, Carl T. Bergstrom, and Charles D. Laird Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5802–5807. Published online 2005 April 12. doi: 10.1073/pnas.0502036102.PMCID: PMC556300 Immunology Stress-induced enhancement of leukocyte trafficking into sites of surgery or immune activation Kavitha Viswanathan and Firdaus S. Dhabhar Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5808–5813. Published online 2005 April 7. doi: 10.1073/pnas.0501650102.PMCID: PMC556309 Medical Sciences Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme Yu Liang, Maximilian Diehn, Nathan Watson, Andrew W. Bollen, Ken D. Aldape, M. Kelly Nicholas, Kathleen R. Lamborn, Mitchel S. Berger, David Botstein, Patrick O. Brown, and Mark A. Israel Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5814–5819. Published online 2005 April 12. doi: 10.1073/pnas.0402870102.PMCID: PMC556127 From the Cover: RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model Scott Q. Harper, Patrick D. Staber, Xiaohua He, Steven L. Eliason, Inês H. Martins, Qinwen Mao, Linda Yang, Robert M. Kotin, Henry L. Paulson, and Beverly L. Davidson Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5820–5825. Published online 2005 April 5. doi: 10.1073/pnas.0501507102.PMCID: PMC556303 Late-onset motoneuron disease caused by a functionally modified AMPA receptor subunit Rohini Kuner, Anthony J. Groom, Iris Bresink, Hans-Christian Kornau, Vanya Stefovska, Gerald Müller, Bettina Hartmann, Karsten Tschauner, Stefan Waibel, Albert C. Ludolph, Chrysanthy Ikonomidou, Peter H. Seeburg, and Lechoslaw Turski Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5826–5831. Published online 2005 April 12. doi: 10.1073/pnas.0501316102.PMCID: PMC556301 Microbiology From the Cover: Targeting of herpesvirus capsid transport in axons is coupled to association with specific sets of tegument proteins G. W. Gant Luxton, Sarah Haverlock, Kelly Elizabeth Coller, Sarah Elizabeth Antinone, Andrew Pincetic, and Gregory Allan Smith Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5832–5837. Published online 2005 March 28. doi: 10.1073/pnas.0500803102.PMCID: PMC556296 Herpes simplex virus 1 infected cell protein 0 forms a complex with CIN85 and Cbl and mediates the degradation of EGF receptor from cell surfaces Yu Liang, Alexei Kurakin, and Bernard Roizman Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5838–5843. Published online 2005 April 11. doi: 10.1073/pnas.0501253102.PMCID: PMC556299 DNA repair proteins affect the lifecycle of herpes simplex virus 1 Caroline E. Lilley, Christian T. Carson, Alysson R. Muotri, Fred H. Gage, and Matthew D. Weitzman Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5844–5849. Published online 2005 April 11. doi: 10.1073/pnas.0501916102.PMCID: PMC556126 Neuroscience Calbindin D28k targets myo-inositol monophosphatase in spines and dendrites of cerebellar Purkinje neurons Hartmut Schmidt, Beat Schwaller, and Jens Eilers Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5850–5855. Published online 2005 April 4. doi: 10.1073/pnas.0407855102.PMCID: PMC556286 The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy Flobert Y. Tanga, Nancy Nutile-McMenemy, and Joyce A. DeLeo Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5856–5861. Published online 2005 April 4. doi: 10.1073/pnas.0501634102.PMCID: PMC556308 Delayed maturation of receptive field center/surround mechanisms in V2 Bin Zhang, Jianghe Zheng, Ichiro Watanabe, Ichiro Maruko, Hua Bi, Earl L. Smith, III, and Yuzo Chino Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5862–5867. Published online 2005 April 11. doi: 10.1073/pnas.0501815102.PMCID: PMC556123 Architectural and synaptic mechanisms underlying coherent spontaneous activity in V1 David Cai, Aaditya V. Rangan, and David W. McLaughlin Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5868–5873. Published online 2005 April 12. doi: 10.1073/pnas.0501913102.PMCID: PMC556291 A pivotal role of calcineurin signaling in development and maturation of postnatal cerebellar granule cells Masaaki Sato, Kazunori Suzuki, Hiroshi Yamazaki, and Shigetada Nakanishi Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5874–5879. Published online 2005 April 4. doi: 10.1073/pnas.0501972102.PMCID: PMC556295 Physiology Nonmammalian gonadotropin-releasing hormone molecules in the brain of promoter transgenic rats Ishwar S. Parhar, Tomoko Soga, Satoshi Ogawa, Sonoko Ogawa, Donald W. Pfaff, and Yasuo Sakuma Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5880–5885. Published online 2005 April 11. doi: 10.1073/pnas.0501832102.PMCID: PMC556124 Plant Biology Xantha-l encodes a membrane subunit of the aerobic Mg-protoporphyrin IX monomethyl ester cyclase involved in chlorophyll biosynthesis Kamila Rzeznicka, Caroline J. Walker, Tomas Westergren, C. Gamini Kannangara, Diter von Wettstein, Sabeeha Merchant, Simon P. Gough, and Mats Hansson Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5886–5891. Published online 2005 April 11. doi: 10.1073/pnas.0501784102.PMCID: PMC556314 From the Cover: Life history biology of early land plants: Deciphering the gametophyte phase Thomas N. Taylor, Hans Kerp, and Hagen Hass Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5892–5897. Published online 2005 April 4. doi: 10.1073/pnas.0501985102.PMCID: PMC556298 |