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Volume 102(16);  April 19, 2005
In This Issue
This Week in PNAS
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5637–5638. doi: 10.1073/iti1605102.
PMCID: PMC556305
Commentaries
Viral trafficking violations in axons: The herpesvirus case
Urs F. Greber
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5639–5640. Published online 2005 April 12. doi: 10.1073/pnas.0501696102.
PMCID: PMC556310
A glimpse at the organization of the protein universe
Michele Vendruscolo and Christopher M. Dobson
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5641–5642. Published online 2005 April 12. doi: 10.1073/pnas.0500274102.
PMCID: PMC556289
Organization of synaptic myonuclei by Syne proteins and their role during the formation of the nerve–muscle synapse
Markus A. Ruegg
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5643–5644. Published online 2005 April 12. doi: 10.1073/pnas.0501516102.
PMCID: PMC556304
Coupling neurotrophins to cell migration through selective guanine nucleotide exchange factor activation
Barbara L. Hempstead
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5645–5646. Published online 2005 April 12. doi: 10.1073/pnas.0501718102.
PMCID: PMC556311
Physical Sciences
Applied Mathematics
Structure theorems and the dynamics of nitrogen catabolite repression in yeast
Erik M. Boczko, Terrance G. Cooper, Tomas Gedeon, Konstantin Mischaikow, Deborah G. Murdock, Siddharth Pratap, and K. Sam Wells
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5647–5652. Published online 2005 April 6. doi: 10.1073/pnas.0501339102.
PMCID: PMC556013
Applied Physical Sciences
Electrical addressing of confined quantum systems for quasiclassical computation and finite state logic machines
F. Remacle, J. R. Heath, and R. D. Levine
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5653–5658. Published online 2005 April 8. doi: 10.1073/pnas.0501623102.
PMCID: PMC556307
Chemistry
From the Cover:
A fullerene molecular tip can detect localized and rectified electron tunneling within a single fullerene–porphyrin pair
Tomoaki Nishino, Takashi Ito, and Yoshio Umezawa
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5659–5662. Published online 2005 April 4. doi: 10.1073/pnas.0408474102.
PMCID: PMC556290
Mathematics
Generalizations of the classical Weyl and Colin de Verdière's formulas and the orbit method
Mitya Boyarchenko and Sergei Levendorskii
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5663–5668. Published online 2005 April 12. doi: 10.1073/pnas.0500444102.
PMCID: PMC556293
Physics
Exact solution of a jamming transition: Closed equations for a bootstrap percolation problem
Paolo De Gregorio, Aonghus Lawlor, Phil Bradley, and Kenneth A. Dawson
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5669–5673. Published online 2005 April 4. doi: 10.1073/pnas.0408756102.
PMCID: PMC556280
Biological Sciences
Anthropology
An Early Pleistocene hominin mandible from Atapuerca-TD6, Spain
E. Carbonell, J. M. Bermúdez de Castro, J. L. Arsuaga, E. Allue, M. Bastir, A. Benito, I. Cáceres, T. Canals, J. C. Díez, J. van der Made, M. Mosquera, A. Ollé, A. Pérez-González, J. Rodríguez, X. P. Rodríguez, A. Rosas, J. Rosell, R. Sala, J. Vallverdú, and J. M. Vergés
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5674–5678. Published online 2005 April 11. doi: 10.1073/pnas.0501841102.
PMCID: PMC556125
Applied Biological Sciences
Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung
Mini Thomas, James J. Lu, Qing Ge, Chengcheng Zhang, Jianzhu Chen, and Alexander M. Klibanov
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5679–5684. Published online 2005 April 11. doi: 10.1073/pnas.0502067102.
PMCID: PMC556302
Biochemistry
The nucleotide switch in Cdc42 modulates coupling between the GTPase-binding and allosteric equilibria of Wiskott–Aldrich syndrome protein
Daisy W. Leung and Michael K. Rosen
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5685–5690. Published online 2005 April 8. doi: 10.1073/pnas.0406472102.
PMCID: PMC556282
Directed evolution of specific receptor–ligand pairs for use in the creation of gene switches
Karuppiah Chockalingam, Zhilei Chen, John A. Katzenellenbogen, and Huimin Zhao
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5691–5696. Published online 2005 April 5. doi: 10.1073/pnas.0409206102.
PMCID: PMC556283
Linker histone variants control chromatin dynamics during early embryogenesis
Hideaki Saeki, Keita Ohsumi, Hitoshi Aihara, Takashi Ito, Susumu Hirose, Kiyoe Ura, and Yasufumi Kaneda
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5697–5702. Published online 2005 April 8. doi: 10.1073/pnas.0409824102.
PMCID: PMC556016
Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability
Alexandra Beilina, Marcel Van Der Brug, Rili Ahmad, Sashi Kesavapany, David W. Miller, Gregory A. Petsko, and Mark R. Cookson
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5703–5708. Published online 2005 April 11. doi: 10.1073/pnas.0500617102.
PMCID: PMC556294
Hemoglobin conformation couples erythrocyte S-nitrosothiol content to O2 gradients
Allan Doctor, Ruth Platt, Mary Lynn Sheram, Anne Eischeid, Timothy McMahon, Thomas Maxey, Joseph Doherty, Mark Axelrod, Jaclyn Kline, Matthew Gurka, Andrew Gow, and Benjamin Gaston
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5709–5714. Published online 2005 April 11. doi: 10.1073/pnas.0407490102.
PMCID: PMC556285
Biophysics
Observing spontaneous branch migration of Holliday junctions one step at a time
Sean A. McKinney, Alasdair D. J. Freeman, David M. J. Lilley, and Taekjip Ha
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5715–5720. Published online 2005 April 11. doi: 10.1073/pnas.0409328102.
PMCID: PMC556122
Local and long-range stability in tandemly arrayed tetratricopeptide repeats
Ewan R. G. Main, Katherine Stott, Sophie E. Jackson, and Lynne Regan
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5721–5726. Published online 2005 April 11. doi: 10.1073/pnas.0404530102.
PMCID: PMC556279
Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence
Hongtao Zhao, Joy Joseph, Henry M. Fales, Edward A. Sokoloski, Rodney L. Levine, Jeannette Vasquez-Vivar, and B. Kalyanaraman
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5727–5732. Published online 2005 April 11. doi: 10.1073/pnas.0501719102.
PMCID: PMC556312
Cell Biology
Uncoupling of the functions of the Arabidopsis VIP1 protein in transient and stable plant genetic transformation by Agrobacterium
Jianxiong Li, Alexander Krichevsky, Manjusha Vaidya, Tzvi Tzfira, and Vitaly Citovsky
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5733–5738. Published online 2005 April 11. doi: 10.1073/pnas.0404118102.
PMCID: PMC556277
Two essential but distinct functions of the mammalian abasic endonuclease
Tadahide Izumi, David B. Brown, C. V. Naidu, Kishor K. Bhakat, Mark A. MacInnes, Hiroshi Saito, David J. Chen, and Sankar Mitra
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5739–5743. Published online 2005 April 11. doi: 10.1073/pnas.0500986102.
PMCID: PMC556297
Developmental Biology
From the Cover:
CcbP, a calcium-binding protein from Anabaena sp. PCC 7120, provides evidence that calcium ions regulate heterocyst differentiation
Yinhong Zhao, Yunming Shi, Weixing Zhao, Xu Huang, Donghui Wang, Neil Brown, Jerry Brand, and Jindong Zhao
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5744–5748. Published online 2005 April 5. doi: 10.1073/pnas.0501782102.
PMCID: PMC556313
Reverse recruitment: The Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation
Balaraj B. Menon, Nayan J. Sarma, Satish Pasula, Stephen J. Deminoff, Kristine A. Willis, Kellie E. Barbara, Brenda Andrews, and George M. Santangelo
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5749–5754. Published online 2005 April 7. doi: 10.1073/pnas.0501768102.
PMCID: PMC556015
Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility
Juxiang Yang, Sergey Medvedev, Junying Yu, Linda C. Tang, Julio E. Agno, Martin M. Matzuk, Richard M. Schultz, and Norman B. Hecht
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5755–5760. Published online 2005 April 11. doi: 10.1073/pnas.0408718102.
PMCID: PMC556278
Ecology
Evolutionary emergence of size-structured food webs
Nicolas Loeuille and Michel Loreau
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5761–5766. Published online 2005 April 11. doi: 10.1073/pnas.0408424102.
PMCID: PMC556288
Evolution
Dramatic variation of the vomeronasal pheromone receptor gene repertoire among five orders of placental and marsupial mammals
Wendy E. Grus, Peng Shi, Ya-ping Zhang, and Jianzhi Zhang
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5767–5772. Published online 2005 March 24. doi: 10.1073/pnas.0501589102.
PMCID: PMC556306
Rates of intron loss and gain: Implications for early eukaryotic evolution
Scott William Roy and Walter Gilbert
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5773–5778. doi: 10.1073/pnas.0500383102.
PMCID: PMC556292
Heterotopic expression of MPF2 is the key to the evolution of the Chinese lantern of Physalis, a morphological novelty in Solanaceae
Chaoying He and Heinz Saedler
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5779–5784. Published online 2005 April 11. doi: 10.1073/pnas.0501877102.
PMCID: PMC556287
Comparative evolutionary genetics of spontaneous mutations affecting fitness in rhabditid nematodes
Charles F. Baer, Frank Shaw, Catherine Steding, Margaret Baumgartner, Alicia Hawkins, Andrew Houppert, Nicole Mason, Marissa Reed, Kevin Simonelic, Wayne Woodard, and Michael Lynch
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5785–5790. Published online 2005 April 4. doi: 10.1073/pnas.0406056102.
PMCID: PMC556281
Evolution and development of facial bone morphology in threespine sticklebacks
Charles B. Kimmel, Bonnie Ullmann, Charline Walker, Catherine Wilson, Mark Currey, Patrick C. Phillips, Michael A. Bell, John H. Postlethwait, and William A. Cresko
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5791–5796. Published online 2005 April 11. doi: 10.1073/pnas.0408533102.
PMCID: PMC556121
Genetics
A checkpoint control linking meiotic S phase and recombination initiation in fission yeast
Yuko Tonami, Hiroshi Murakami, Katsuhiko Shirahige, and Makoto Nakanishi
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5797–5801. Published online 2005 April 1. doi: 10.1073/pnas.0407236102.
PMCID: PMC556284
A population-epigenetic model to infer site-specific methylation rates from double-stranded DNA methylation patterns
Diane P. Genereux, Brooks E. Miner, Carl T. Bergstrom, and Charles D. Laird
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5802–5807. Published online 2005 April 12. doi: 10.1073/pnas.0502036102.
PMCID: PMC556300
Immunology
Stress-induced enhancement of leukocyte trafficking into sites of surgery or immune activation
Kavitha Viswanathan and Firdaus S. Dhabhar
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5808–5813. Published online 2005 April 7. doi: 10.1073/pnas.0501650102.
PMCID: PMC556309
Medical Sciences
Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme
Yu Liang, Maximilian Diehn, Nathan Watson, Andrew W. Bollen, Ken D. Aldape, M. Kelly Nicholas, Kathleen R. Lamborn, Mitchel S. Berger, David Botstein, Patrick O. Brown, and Mark A. Israel
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5814–5819. Published online 2005 April 12. doi: 10.1073/pnas.0402870102.
PMCID: PMC556127
From the Cover:
RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model
Scott Q. Harper, Patrick D. Staber, Xiaohua He, Steven L. Eliason, Inês H. Martins, Qinwen Mao, Linda Yang, Robert M. Kotin, Henry L. Paulson, and Beverly L. Davidson
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5820–5825. Published online 2005 April 5. doi: 10.1073/pnas.0501507102.
PMCID: PMC556303
Late-onset motoneuron disease caused by a functionally modified AMPA receptor subunit
Rohini Kuner, Anthony J. Groom, Iris Bresink, Hans-Christian Kornau, Vanya Stefovska, Gerald Müller, Bettina Hartmann, Karsten Tschauner, Stefan Waibel, Albert C. Ludolph, Chrysanthy Ikonomidou, Peter H. Seeburg, and Lechoslaw Turski
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5826–5831. Published online 2005 April 12. doi: 10.1073/pnas.0501316102.
PMCID: PMC556301
Microbiology
From the Cover:
Targeting of herpesvirus capsid transport in axons is coupled to association with specific sets of tegument proteins
G. W. Gant Luxton, Sarah Haverlock, Kelly Elizabeth Coller, Sarah Elizabeth Antinone, Andrew Pincetic, and Gregory Allan Smith
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5832–5837. Published online 2005 March 28. doi: 10.1073/pnas.0500803102.
PMCID: PMC556296
Herpes simplex virus 1 infected cell protein 0 forms a complex with CIN85 and Cbl and mediates the degradation of EGF receptor from cell surfaces
Yu Liang, Alexei Kurakin, and Bernard Roizman
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5838–5843. Published online 2005 April 11. doi: 10.1073/pnas.0501253102.
PMCID: PMC556299
DNA repair proteins affect the lifecycle of herpes simplex virus 1
Caroline E. Lilley, Christian T. Carson, Alysson R. Muotri, Fred H. Gage, and Matthew D. Weitzman
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5844–5849. Published online 2005 April 11. doi: 10.1073/pnas.0501916102.
PMCID: PMC556126
Neuroscience
Calbindin D28k targets myo-inositol monophosphatase in spines and dendrites of cerebellar Purkinje neurons
Hartmut Schmidt, Beat Schwaller, and Jens Eilers
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5850–5855. Published online 2005 April 4. doi: 10.1073/pnas.0407855102.
PMCID: PMC556286
The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy
Flobert Y. Tanga, Nancy Nutile-McMenemy, and Joyce A. DeLeo
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5856–5861. Published online 2005 April 4. doi: 10.1073/pnas.0501634102.
PMCID: PMC556308
Delayed maturation of receptive field center/surround mechanisms in V2
Bin Zhang, Jianghe Zheng, Ichiro Watanabe, Ichiro Maruko, Hua Bi, Earl L. Smith, III, and Yuzo Chino
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5862–5867. Published online 2005 April 11. doi: 10.1073/pnas.0501815102.
PMCID: PMC556123
Architectural and synaptic mechanisms underlying coherent spontaneous activity in V1
David Cai, Aaditya V. Rangan, and David W. McLaughlin
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5868–5873. Published online 2005 April 12. doi: 10.1073/pnas.0501913102.
PMCID: PMC556291
A pivotal role of calcineurin signaling in development and maturation of postnatal cerebellar granule cells
Masaaki Sato, Kazunori Suzuki, Hiroshi Yamazaki, and Shigetada Nakanishi
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5874–5879. Published online 2005 April 4. doi: 10.1073/pnas.0501972102.
PMCID: PMC556295
Physiology
Nonmammalian gonadotropin-releasing hormone molecules in the brain of promoter transgenic rats
Ishwar S. Parhar, Tomoko Soga, Satoshi Ogawa, Sonoko Ogawa, Donald W. Pfaff, and Yasuo Sakuma
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5880–5885. Published online 2005 April 11. doi: 10.1073/pnas.0501832102.
PMCID: PMC556124
Plant Biology
Xantha-l encodes a membrane subunit of the aerobic Mg-protoporphyrin IX monomethyl ester cyclase involved in chlorophyll biosynthesis
Kamila Rzeznicka, Caroline J. Walker, Tomas Westergren, C. Gamini Kannangara, Diter von Wettstein, Sabeeha Merchant, Simon P. Gough, and Mats Hansson
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5886–5891. Published online 2005 April 11. doi: 10.1073/pnas.0501784102.
PMCID: PMC556314
From the Cover:
Life history biology of early land plants: Deciphering the gametophyte phase
Thomas N. Taylor, Hans Kerp, and Hagen Hass
Proc Natl Acad Sci U S A. 2005 April 19; 102(16): 5892–5897. Published online 2005 April 4. doi: 10.1073/pnas.0501985102.
PMCID: PMC556298
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