| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 March 1; 102(9): 3171–3172. doi: 10.1073/iti0905102.PMCID: PMC552947 Commentaries Lasting impressions: Motifs in protein–protein maps may provide footprints of evolutionary events J. Jeremy Rice, Aaron Kershenbaum, and Gustavo Stolovitzky PMCID: PMC552913 Balancing the generation and elimination of reactive oxygen species Rusty Rodriguez and Regina Redman PMCID: PMC552941 The independence of language and mathematical reasoning Elizabeth M. Brannon PMCID: PMC552939 The power of phylogenetic comparison in revealing protein function Ziheng Yang PMCID: PMC552944 Biography INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of Cornelia I. Bargmann Melissa Marino PMCID: PMC552904 Physical Sciences Applied Mathematics From the Cover:
Inferring network mechanisms: The Drosophila melanogaster protein interaction network Manuel Middendorf, Etay Ziv, and Chris H. Wiggins PMCID: PMC552930 Applied Physical Sciences Hard superconducting nitrides Xiao-Jia Chen, Viktor V. Struzhkin, Zhigang Wu, Maddury Somayazulu, Jiang Qian, Simon Kung, Axel Nørlund Christensen, Yusheng Zhao, Ronald E. Cohen, Ho-kwang Mao, and Russell J. Hemley PMCID: PMC552926 Chemistry Dynamics of confined water molecules J. J. Gilijamse, A. J. Lock, and H. J. Bakker PMCID: PMC552901 Label-free detection of small-molecule–protein interactions by using nanowire nanosensors Wayne U. Wang, Chuo Chen, Keng-hui Lin, Ying Fang, and Charles M. Lieber PMCID: PMC548960 Engineering Growth and shape stability of a biological membrane adhesion complex in the diffusion-mediated regime V. B. Shenoy and L. B. Freund PMCID: PMC549294 Biological Sciences Applied Biological Sciences Mullerian inhibiting substance suppresses tumor growth in the C3(1)T antigen transgenic mouse mammary carcinoma model V. Gupta, J. L. Carey, H. Kawakubo, A. Muzikansky, J. E. Green, P. K. Donahoe, D. T. MacLaughlin, and S. Maheswaran PMCID: PMC552936 Biochemistry Structure of a mitochondrial supercomplex formed by respiratory-chain complexes I and III Natalia V. Dudkina, Holger Eubel, Wilko Keegstra, Egbert J. Boekema, and Hans-Peter Braun PMCID: PMC552927 The initial substrate-binding site of γ-secretase is located on presenilin near the active site Anna Y. Kornilova, Frédéric Bihel, Chittaranjan Das, and Michael S. Wolfe PMCID: PMC552920 Identification of a nitrogenase FeMo cofactor precursor on NifEN complex Yilin Hu, Aaron W. Fay, and Markus W. Ribbe PMCID: PMC552928 Intramembrane aspartic acid in SCAP protein governs cholesterol-induced conformational change Jamison D. Feramisco, Arun Radhakrishnan, Yukio Ikeda, Julian Reitz, Michael S. Brown, and Joseph L. Goldstein PMCID: PMC552931 Crystal structure of DNA sequence specificity subunit of a type I restriction-modification enzyme and its functional implications Jeong-Sun Kim, Andy DeGiovanni, Jaru Jancarik, Paul D. Adams, Hisao Yokota, Rosalind Kim, and Sung-Hou Kim PMCID: PMC549290 Assembly of the bacteriophage T4 primosome: Single-molecule and ensemble studies Zhiquan Zhang, Michelle M. Spiering, Michael A. Trakselis, Faoud T. Ishmael, Jun Xi, Stephen J. Benkovic, and Gordon G. Hammes PMCID: PMC552937 Study of the high-potential iron sulfur protein in Halorhodospira halophila confirms that it is distinct from cytochrome c as electron carrier Clément Lieutaud, Jean Alric, Marielle Bauzan, Wolfgang Nitschke, and Barbara Schoepp-Cothenet PMCID: PMC552902 The eukaryotic P loop NTPase Nbp35: An essential component of the cytosolic and nuclear iron–sulfur protein assembly machinery Anja Hausmann, Daili J. Aguilar Netz, Janneke Balk, Antonio J. Pierik, Ulrich Mühlenhoff, and Roland Lill PMCID: PMC552912 From the Cover:
Sterol structure determines the separation of phases and the curvature of the liquid-ordered phase in model membranes Kirsten Bacia, Petra Schwille, and Teymuras Kurzchalia PMCID: PMC552914 Biophysics Label-free detection of small-molecule–protein interactions by using nanowire nanosensors Wayne U. Wang, Chuo Chen, Keng-hui Lin, Ying Fang, and Charles M. Lieber PMCID: PMC548960 Growth and shape stability of a biological membrane adhesion complex in the diffusion-mediated regime V. B. Shenoy and L. B. Freund PMCID: PMC549294 Fast, long-range, reversible conformational fluctuations in nucleosomes revealed by single-pair fluorescence resonance energy transfer Miroslav Tomschik, Haocheng Zheng, Ken van Holde, Jordanka Zlatanova, and Sanford H. Leuba PMCID: PMC549292 Probing site-specific conformational distributions in protein folding with solid-state NMR Robert H. Havlin and Robert Tycko PMCID: PMC552907 Cell Biology Barrier-to-autointegration factor is required to segregate and enclose chromosomes within the nuclear envelope and assemble the nuclear lamina Ayelet Margalit, Miriam Segura-Totten, Yosef Gruenbaum, and Katherine L. Wilson PMCID: PMC552915 Human mesenchymal stem cells in rodent whole-embryo culture are reprogrammed to contribute to kidney tissues Takashi Yokoo, Toya Ohashi, Jin Song Shen, Ken Sakurai, Yoichi Miyazaki, Yasunori Utsunomiya, Masanori Takahashi, Yoshio Terada, Yoshikatsu Eto, Tetsuya Kawamura, Noriko Osumi, and Tatsuo Hosoya PMCID: PMC552897 Rhodopsin C terminus, the site of mutations causing retinal disease, regulates trafficking by binding to ADP-ribosylation factor 4 (ARF4) Dusanka Deretic, Andrew H. Williams, Nancy Ransom, Valerie Morel, Paul A. Hargrave, and Anatol Arendt PMCID: PMC552909 Molecular cloning of TRPC3a, an N-terminally extended, store-operated variant of the human C3 transient receptor potential channel Eda Yildirim, Brian T. Kawasaki, and Lutz Birnbaumer PMCID: PMC552946 Developmental Biology Enforced Bcl-2 expression overrides serum and feeder cell requirements for mouse embryonic stem cell self-renewal Toshiyuki Yamane, Scott J. Dylla, Manja Muijtjens, and Irving L. Weissman PMCID: PMC552922 Mechanical feedback as a possible regulator of tissue growth Boris I. Shraiman PMCID: PMC552900 Regulation of osteoblastogenesis and bone mass by Wnt10b Christina N. Bennett, Kenneth A. Longo, Wendy S. Wright, Larry J. Suva, Timothy F. Lane, Kurt D. Hankenson, and Ormond A. MacDougald PMCID: PMC552924 Evolution Juvenile hormone, reproduction, and worker behavior in the neotropical social wasp Polistes canadensis Tugrul Giray, Manuela Giovanetti, and Mary Jane West-Eberhard PMCID: PMC552932 Genetics Association of tissue-specific differentially methylated regions (TDMs) with differential gene expression Fei Song, Joseph F. Smith, Makoto T. Kimura, Arlene D. Morrow, Tomoki Matsuyama, Hiroki Nagase, and William A. Held PMCID: PMC552919 Mutations in Serac1 or Synj2 cause proximal t haplotype-mediated male mouse sterility but not transmission ratio distortion John C. Schimenti, Jennifer L. Reynolds, and Antonio Planchart PMCID: PMC552908 Abrupt disruption of capping and a single source for recombinationally elongated telomeres in Kluyveromyces lactis Zeki Topcu, Kristy Nickles, Charity Davis, and Michael J. McEachern PMCID: PMC552925 Comparative sequencing provides insights about the structure and conservation of marsupial and monotreme genomes Elliott H. Margulies, NISC Comparative Sequencing Program, Valerie V. B. Maduro, Pamela J. Thomas, Jeffery P. Tomkins, Chris T. Amemiya, Meizhong Luo, and Eric D. Green PMCID: PMC549084 Immunology Crystal structure of HLA-G: A nonclassical MHC class I molecule expressed at the fetal–maternal interface Craig S. Clements, Lars Kjer-Nielsen, Lyudmila Kostenko, Hilary L. Hoare, Michelle A. Dunstone, Eric Moses, Katy Freed, Andrew G. Brooks, Jamie Rossjohn, and James McCluskey PMCID: PMC552935 An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin αLβ2 Gang Song, Yuting Yang, Jin-huan Liu, Jose M. Casasnovas, Motomu Shimaoka, Timothy A. Springer, and Jia-huai Wang PMCID: PMC552929 Cross-regulation of TNF and IFN-α in autoimmune diseases A. Karolina Palucka, Jean-Philippe Blanck, Lynda Bennett, Virginia Pascual, and Jacques Banchereau PMCID: PMC552921 Immunogenicity in humans of an edible vaccine for hepatitis B Yasmin Thanavala, Martin Mahoney, Sribani Pal, Adrienne Scott, Liz Richter, Nachimuthu Natarajan, Patti Goodwin, Charles J. Arntzen, and Hugh S. Mason PMCID: PMC549291 Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of α-galactosylceramides Karl O. A. Yu, Jin S. Im, Alberto Molano, Yves Dutronc, Petr A. Illarionov, Claire Forestier, Nagatoshi Fujiwara, Isa Arias, Sachiko Miyake, Takashi Yamamura, Young-Tae Chang, Gurdyal S. Besra, and Steven A. Porcelli PMCID: PMC552918 Medical Sciences Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma Jean S. Campbell, Steven D. Hughes, Debra G. Gilbertson, Thomas E. Palmer, Matthew S. Holdren, Aaron C. Haran, Melissa M. Odell, Renay L. Bauer, Hong-Ping Ren, Harald S. Haugen, Matthew M. Yeh, and Nelson Fausto PMCID: PMC552940 Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance Michael R. Burgess, Brian J. Skaggs, Neil P. Shah, Francis Y. Lee, and Charles L. Sawyers PMCID: PMC552942 Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis Timothy P. Dalton, Lei He, Bin Wang, Marian L. Miller, Li Jin, Keith F. Stringer, Xiaoqing Chang, C. Stuart Baxter, and Daniel W. Nebert PMCID: PMC552906 From the Cover:
Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex Victoria Y. Gorbacheva, Roman V. Kondratov, Renliang Zhang, Srujana Cherukuri, Andrei V. Gudkov, Joseph S. Takahashi, and Marina P. Antoch PMCID: PMC546637 Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein Francesco Fornai, Oliver M. Schlüter, Paola Lenzi, Marco Gesi, Riccardo Ruffoli, Michela Ferrucci, Gloria Lazzeri, Carla L. Busceti, Fabrizio Pontarelli, Giuseppe Battaglia, Antonio Pellegrini, Ferdinando Nicoletti, Stefano Ruggieri, Antonio Paparelli, and Thomas C. Südhof PMCID: PMC552938 Microcomputed tomography colonography for polyp detection in an in vivo mouse tumor model Perry J. Pickhardt, Richard B. Halberg, Andrew J. Taylor, Ben Y. Durkee, Jason Fine, Fred T. Lee, Jr., and Jamey P. Weichert PMCID: PMC552949 Circulating transcriptome reveals markers of atherosclerosis Willmar D. Patino, Omar Y. Mian, Ju-Gyeong Kang, Satoaki Matoba, Linda D. Bartlett, Brenda Holbrook, Hugh H. Trout, III, Louis Kozloff, and Paul M. Hwang PMCID: PMC552911 Synergistic proinflammatory responses induced by polymicrobial colonization of epithelial surfaces Adam J. Ratner, Elena S. Lysenko, Marina N. Paul, and Jeffrey N. Weiser PMCID: PMC552945 Antagonist of growth hormone-releasing hormone induces apoptosis in LNCaP human prostate cancer cells through a Ca2+-dependent pathway Zoltan Rekasi, Tamas Czompoly, Andrew V. Schally, Ferenc Boldizsar, Jozsef L. Varga, Marta Zarandi, Timea Berki, Reka A. Horvath, and Peter Nemeth PMCID: PMC552899 Microbiology Genome trimming: A unique strategy for replication control employed by Borna disease virus Urs Schneider, Martin Schwemmle, and Peter Staeheli PMCID: PMC552903 Chlamydia pneumoniae infection promotes a proliferative phenotype in the vasculature through Egr-1 activation in vitro and in vivo Jan Rupp, Thomas Hellwig-Burgel, Viola Wobbe, Ulrike Seitzer, Ernst Brandt, and Matthias Maass PMCID: PMC552898 Lessons from Escherichia coli genes similarly regulated in response to nitrogen and sulfur limitation Prasad Gyaneshwar, Oleg Paliy, Jon McAuliffe, Adriane Jones, Michael I. Jordan, and Sydney Kustu PMCID: PMC552917 From the Cover:
Proline suppresses apoptosis in the fungal pathogen Colletotrichum trifolii Changbin Chen and Martin B. Dickman PMCID: PMC552905 Genomic characterization of non-O1, non-O139 Vibrio cholerae reveals genes for a type III secretion system Michelle Dziejman, Davide Serruto, Vincent C. Tam, Derek Sturtevant, Pornphan Diraphat, Shah M. Faruque, M. Hasibur Rahman, John F. Heidelberg, Jeremy Decker, Li Li, Kate T. Montgomery, George Grills, Raju Kucherlapati, and John J. Mekalanos PMCID: PMC552950 Demonstration of toxicity to fish and to mammalian cells by Pfiesteria species: Comparison of assay methods and strains JoAnn M. Burkholder, Andrew S. Gordon, Peter D. Moeller, J. Mac Law, Kathryn J. Coyne, Alan J. Lewitus, John S. Ramsdell, Harold G. Marshall, Nora J. Deamer, S. Craig Cary, Jason W. Kempton, Steven L. Morton, and Parke A. Rublee PMCID: PMC552923 Neuroscience INAUGURAL ARTICLE by a Recently Elected Academy Member: A circuit for navigation in Caenorhabditis elegansJesse M. Gray, Joseph J. Hill, and Cornelia I. Bargmann PMCID: PMC546636 Dissection of synaptic excitability phenotypes by using a dominant-negative Shaker K+ channel subunit Timothy J. Mosca, Robert A. Carrillo, Benjamin H. White, and Haig Keshishian PMCID: PMC552910 Uric acid protects against secondary damage after spinal cord injury Gwen S. Scott, Salvatore Cuzzocrea, Tiziana Genovese, Hilary Koprowski, and D. Craig Hooper PMCID: PMC552934 Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5) Marie Futter, Ken Uematsu, Stewart A. Bullock, Yong Kim, Hugh C. Hemmings, Jr., Akinori Nishi, Paul Greengard, and Angus C. Nairn PMCID: PMC552943 Amphetamine induces dopamine efflux through a dopamine transporter channel Kristopher M. Kahlig, Francesca Binda, Habibeh Khoshbouei, Randy D. Blakely, Douglas G. McMahon, Jonathan A. Javitch, and Aurelio Galli PMCID: PMC549289 Diagnosis of human prion disease Jiri G. Safar, Michael D. Geschwind, Camille Deering, Svetlana Didorenko, Mamta Sattavat, Henry Sanchez, Ana Serban, Martin Vey, Henry Baron, Kurt Giles, Bruce L. Miller, Stephen J. DeArmond, and Stanley B. Prusiner PMCID: PMC552933 Single-neuron responses and neuronal decisions in a vernier task Ying Zhang and R. Clay Reid PMCID: PMC552948 Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis Philip Seeman, David Weinshenker, Remi Quirion, Lalit K. Srivastava, Sanjeev K. Bhardwaj, David K. Grandy, Richard T. Premont, Tatyana D. Sotnikova, Patricia Boksa, Mufida El-Ghundi, Brian F. O'Dowd, Susan R. George, Melissa L. Perreault, Pekka T. Männistö, Siobhan Robinson, Richard D. Palmiter, and Teresa Tallerico PMCID: PMC548961 Psychology From the Cover:
Agrammatic but numerate Rosemary A. Varley, Nicolai J. C. Klessinger, Charles A. J. Romanowski, and Michael Siegal PMCID: PMC552916 |
