| | This journal provides immediate access to some articles. Commentaries The unpredictable past of Plasmodium vivax revealed in its genome Stephen M. Rich PMCID: PMC524848 Viruses and the physics of soft condensed matter Adam Zlotnick PMCID: PMC524855 Physical Sciences Applied Mathematics From the Cover:
Emergence of complex dynamics in a simple model of signaling networks Luís A. N. Amaral, Albert Díaz-Guilera, Andre A. Moreira, Ary L. Goldberger, and Lewis A. Lipsitz PMCID: PMC524828 Physics From the Cover:
Origin of icosahedral symmetry in viruses Roya Zandi, David Reguera, Robijn F. Bruinsma, William M. Gelbart, and Joseph Rudnick PMCID: PMC524849 Statistics A system for enhancing genome-wide coexpression dynamics study Ker-Chau Li, Ching-Ti Liu, Wei Sun, Shinsheng Yuan, and Tianwei Yu PMCID: PMC524832 Biological Sciences Biochemistry Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain Bornali Chakravarty, Ziwei Gu, Subrahmanyam S. Chirala, Salih J. Wakil, and Florante A. Quiocho PMCID: PMC524853 Total synthesis of long DNA sequences: Synthesis of a contiguous 32-kb polyketide synthase gene cluster Sarah J. Kodumal, Kedar G. Patel, Ralph Reid, Hugo G. Menzella, Mark Welch, and Daniel V. Santi PMCID: PMC524854 A single active site residue directs oxygenation stereospecificity in lipoxygenases: Stereocontrol is linked to the position of oxygenation Gianguido Coffa and Alan R. Brash PMCID: PMC524819 Selective interaction between nonribosomal peptide synthetases is facilitated by short communication-mediating domains Martin Hahn and Torsten Stachelhaus PMCID: PMC524835 A systematic method for identifying small-molecule modulators of protein–protein interactions Alexander R. Horswill, Sergey N. Savinov, and Stephen J. Benkovic PMCID: PMC524857 Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription Seiji Ishii, Katsumi IIzuka, Bonnie C. Miller, and Kosaku Uyeda PMCID: PMC524841 From the Cover:
Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes Jen-Chywan Wang, Mika Kakefuda Derynck, Daisuke F. Nonaka, Daniel B. Khodabakhsh, Chris Haqq, and Keith R. Yamamoto PMCID: PMC524211 EncM, a versatile enterocin biosynthetic enzyme involved in Favorskii oxidative rearrangement, aldol condensation, and heterocycle-forming reactions Longkuan Xiang, John A. Kalaitzis, and Bradley S. Moore PMCID: PMC524846 Self/nonself recognition in ascidian fertilization: Vitelline coat protein HrVC70 is a candidate allorecognition molecule Hitoshi Sawada, Etsuko Tanaka, Susumu Ban, Chiho Yamasaki, Junko Fujino, Kazuto Ooura, Yukichi Abe, Ken-ichi Matsumoto, and Hideyoshi Yokosawa PMCID: PMC524827 Biophysics AtTPK4, an Arabidopsis tandem-pore K+ channel, poised to control the pollen membrane voltage in a pH- and Ca2+-dependent manner D. Becker, D. Geiger, M. Dunkel, A. Roller, A. Bertl, A. Latz, A. Carpaneto, P. Dietrich, M. R. G. Roelfsema, C. Voelker, D. Schmidt, B. Mueller-Roeber, K. Czempinski, and R. Hedrich PMCID: PMC524823 Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP Brad J. Nolen, Ryan S. Littlefield, and Thomas D. Pollard PMCID: PMC524860 Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan Paul G. Scott, Paul A. McEwan, Carole M. Dodd, Ernst M. Bergmann, Paul N. Bishop, and Jordi Bella PMCID: PMC524833 Barrier-limited, microsecond folding of a stable protein measured with hydrogen exchange: Implications for downhill folding W. Kevin Meisner and Tobin R. Sosnick PMCID: PMC524831 Crystal structure of 4-hydroxybutyryl-CoA dehydratase: Radical catalysis involving a [4Fe–4S] cluster and flavin Berta M. Martins, Holger Dobbek, Irfan Çinkaya, Wolfgang Buckel, and Albrecht Messerschmidt PMCID: PMC524839 Cell Biology Effect of torsinA on membrane proteins reveals a loss of function and a dominant-negative phenotype of the dystonia-associated ΔE-torsinA mutant Gonzalo E. Torres, Ava L. Sweeney, Jean-Martin Beaulieu, Pullani Shashidharan, and Marc G. Caron PMCID: PMC524822 Developmental Biology Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment Marcela Guzman-Ayala, Nadav Ben-Haim, Séverine Beck, and Daniel B. Constam PMCID: PMC524845 Ecology From the Cover:
Growth and hydraulic (not mechanical) constraints govern the scaling of tree height and mass Karl J. Niklas and Hanns-Christof Spatz PMCID: PMC524850 The relationship between regional and local species diversity in marine benthic communities: A global perspective Jon D. Witman, Ron J. Etter, and Franz Smith PMCID: PMC524210 Evolution Epistatic interaction between Arabidopsis FRI and FLC flowering time genes generates a latitudinal cline in a life history trait Ana L. Caicedo, John R. Stinchcombe, Kenneth M. Olsen, Johanna Schmitt, and Michael D. Purugganan PMCID: PMC524852 Genetics A system for enhancing genome-wide coexpression dynamics study Ker-Chau Li, Ching-Ti Liu, Wei Sun, Shinsheng Yuan, and Tianwei Yu PMCID: PMC524832 Correction of ATM gene function by aminoglycoside-induced read-through of premature termination codons Chih-Hung Lai, Helen H. Chun, Shareef A. Nahas, Midori Mitui, Kristin M. Gamo, Liutao Du, and Richard A. Gatti PMCID: PMC524838 Combining biological networks to predict genetic interactions Sharyl L. Wong, Lan V. Zhang, Amy H. Y. Tong, Zhijian Li, Debra S. Goldberg, Oliver D. King, Guillaume Lesage, Marc Vidal, Brenda Andrews, Howard Bussey, Charles Boone, and Frederick P. Roth PMCID: PMC524818 Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family Yonghong Li, Petra Nowotny, Peter Holmans, Scott Smemo, John S. K. Kauwe, Anthony L. Hinrichs, Kristina Tacey, Lisa Doil, Ryan van Luchene, Veronica Garcia, Charles Rowland, Steve Schrodi, Diane Leong, Goran Gogic, Joanne Chan, Anibal Cravchik, David Ross, Kit Lau, Shirley Kwok, Sheng-Yung Chang, Joe Catanese, John Sninsky, Thomas J. White, John Hardy, John Powell, Simon Lovestone, John C. Morris, Leon Thal, Michael Owen, Julie Williams, Alison Goate, and Andrew Grupe PMCID: PMC524264 Formation of deletions during double-strand break repair in Drosophila DmBlm mutants occurs after strand invasion Mitch McVey, Jeannine R. LaRocque, Melissa D. Adams, and Jeff J. Sekelsky PMCID: PMC524851 Variation in sequence and organization of splicing regulatory elements in vertebrate genes Gene Yeo, Shawn Hoon, Byrappa Venkatesh, and Christopher B. Burge PMCID: PMC524216 Immunology Resolution of the novel immune-type receptor gene cluster in zebrafish Jeffrey A. Yoder, Ronda T. Litman, M. Gail Mueller, Salil Desai, Kimberly P. Dobrinski, Jennifer S. Montgomery, Matthew P. Buzzeo, Tatsuya Ota, Chris T. Amemiya, Nikolaus S. Trede, Sheng Wei, Julie Y. Djeu, Sean Humphray, Kerstin Jekosch, Jose A. Hernandez Prada, David A. Ostrov, and Gary W. Litman PMCID: PMC524843 The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor β locus Stéphanie Eyquem, Karine Chemin, Magali Fasseu, and Jean-Christophe Bories PMCID: PMC524847 Medical Sciences The gut microbiota as an environmental factor that regulates fat storage Fredrik Bäckhed, Hao Ding, Ting Wang, Lora V. Hooper, Gou Young Koh, Andras Nagy, Clay F. Semenkovich, and Jeffrey I. Gordon PMCID: PMC524219 Large-scale cDNA transfection screening for genes related to cancer development and progression Dafang Wan, Yi Gong, Wenxin Qin, Pingping Zhang, Jinjun Li, Lin Wei, Xiaomei Zhou, Hongnian Li, Xiaokun Qiu, Fei Zhong, Liping He, Jian Yu, Genfu Yao, Huiqiu Jiang, Lianfang Qian, Ye Yu, Huiqun Shu, Xianlian Chen, Huili Xu, Minglei Guo, Zhimei Pan, Yan Chen, Chao Ge, Shengli Yang, and Jianren Gu PMCID: PMC524842 Epstein–Barr virus-encoded LMP2A regulates viral and cellular gene expression by modulation of the NF-κB transcription factor pathway Suzanne Stewart, Christopher W. Dawson, Kenzo Takada, John Curnow, Cary A. Moody, John W. Sixbey, and Lawrence S. Young PMCID: PMC524829 A β-oxidation-resistant lipoxin A4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction Stefano Fiorucci, John L. Wallace, Andrea Mencarelli, Eleonora Distrutti, Giovanni Rizzo, Silvana Farneti, Antonio Morelli, Jih-Lie Tseng, Babu Suramanyam, William J. Guilford, and John F. Parkinson PMCID: PMC524215 Microbiology Three distinct suppressors of RNA silencing encoded by a 20-kb viral RNA genome Rui Lu, Alexey Folimonov, Michael Shintaku, Wan-Xiang Li, Bryce W. Falk, William O. Dawson, and Shou-Wei Ding PMCID: PMC524217 CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus Scott A. Jeffers, Sonia M. Tusell, Laura Gillim-Ross, Erin M. Hemmila, Jenna E. Achenbach, Gregory J. Babcock, William D. Thomas, Jr., Larissa B. Thackray, Mark D. Young, Robert J. Mason, Donna M. Ambrosino, David E. Wentworth, James C. DeMartini, and Kathryn V. Holmes PMCID: PMC524836 Conserved residues in the Plasmodium vivax Duffy-binding protein ligand domain are critical for erythrocyte receptor recognition Kelley M. VanBuskirk, Elitza Sevova, and John H. Adams PMCID: PMC524844 A biochemical oscillator explains several aspects of Myxococcus xanthus behavior during development Oleg A. Igoshin, Albert Goldbeter, Dale Kaiser, and George Oster PMCID: PMC524859 Neuroscience Convergence of excitatory and inhibitory hair cell transmitters shapes vestibular afferent responses Gay R. Holstein, Richard D. Rabbitt, Giorgio P. Martinelli, Victor L. Friedrich, Jr., Richard D. Boyle, and Stephen M. Highstein PMCID: PMC524830 Facile isolation and the characterization of human retinal stem cells Brenda L. K. Coles, Brigitte Angénieux, Tomoyuki Inoue, Katia Del Rio-Tsonis, Jason R. Spence, Roderick R. McInnes, Yvan Arsenijevic, and Derek van der Kooy PMCID: PMC524825 Organization of a primitive memory: Olfaction P.-G. de Gennes PMCID: PMC524837 Modulation of dendritic differentiation by corticotropin-releasing factor in the developing hippocampus Yuncai Chen, Roland A. Bender, Kristen L. Brunson, Jörn K. Pomper, Dimitri E. Grigoriadis, Wolfgang Wurst, and Tallie Z. Baram PMCID: PMC524840 Induction of long-term potentiation and depression is reflected by corresponding changes in secretion of endogenous brain-derived neurotrophic factor Giorgio Aicardi, Emanuela Argilli, Silvia Cappello, Spartaco Santi, Massimo Riccio, Hans Thoenen, and Marco Canossa PMCID: PMC524856 Physiology Conformational activation of Ca2+ entry by depolarization of skeletal myotubes Gennady Cherednichenko, Alanna M. Hurne, James D. Fessenden, Eun Hui Lee, Paul D. Allen, Kurt G. Beam, and Isaac N. Pessah PMCID: PMC524834 Role of proneuregulin 1 cleavage and human epidermal growth factor receptor activation in hypertonic aquaporin induction Andreas Herrlich, Virginia Leitch, and Landon S. King PMCID: PMC524821 Plant Biology Expression of antiapoptotic genes bcl-xL and ced-9 in tomato enhances tolerance to viral-induced necrosis and abiotic stress Ping Xu, Stephanie J. Rogers, and Marilyn J. Roossinck PMCID: PMC524858 From the Cover:
Innate immunity in Arabidopsis thaliana: Lipopolysaccharides activate nitric oxide synthase (NOS) and induce defense genes Dana Zeidler, Ulrich Zähringer, Isak Gerber, Ian Dubery, Thomas Hartung, Wolf Bors, Peter Hutzler, and Jörg Durner PMCID: PMC524824 Integration of reproductive meristem fates by a SEPALLATA-like MADS-box gene Anne Uimari, Mika Kotilainen, Paula Elomaa, Deyue Yu, Victor A. Albert, and Teemu H. Teeri PMCID: PMC524820 Correction Proc Natl Acad Sci U S A. 2004 November 2; 101(44): 15823. Published online 2004 October 21. doi: 10.1073/pnas.0401727101.PMCID: PMC524826 Corrects: D. N. Angelov, et al. Therapeutic vaccine for acute and chronic motor neuron diseases: Implications for amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A. 2003 April 15; 100(8): 4790–4795. |
