| | This journal provides immediate access to some articles. Commentaries Cycling antibiotics may not be good for your health Bruce R. Levin and Marc J. M. Bonten PMCID: PMC516530 Homeostatic regulation of dopaminergic neurons without dopamine D. James Surmeier PMCID: PMC516531 Perspective O2 activation by binuclear Cu sites: Noncoupled versus exchange coupled reaction mechanisms Peng Chen and Edward I. Solomon PMCID: PMC516532 Physical Sciences Applied Mathematics Vaccination and the theory of games Chris T. Bauch and David J. D. Earn PMCID: PMC516577 Chemistry Exploring the O-GlcNAc proteome: Direct identification of O-GlcNAc-modified proteins from the brain Nelly Khidekel, Scott B. Ficarro, Eric C. Peters, and Linda C. Hsieh-Wilson PMCID: PMC516536 Colossal kinetic isotope effects in proton-coupled electron transfer My Hang V. Huynh and Thomas J. Meyer PMCID: PMC516537 Physics Measurement of anisotropic energy transport in flowing polymers by using a holographic technique Jay D. Schieber, David C. Venerus, Kendall Bush, Venkat Balasubramanian, and Stoyan Smoukov PMCID: PMC516538 Biological Sciences Biochemistry INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of Barry S. Coller Christen Brownlee PMCID: PMC516533 INAUGURAL ARTICLE by a Recently Elected Academy Member: Integrin β3 regions controlling binding of murine mAb 7E3: Implications for the mechanism of integrin αIIbβ3 activation Andrea Artoni, JiHong Li, Beau Mitchell, Jian Ruan, Junichi Takagi, Timothy A. Springer, Deborah L. French, and Barry S. Coller PMCID: PMC516524 Exploring the O-GlcNAc proteome: Direct identification of O-GlcNAc-modified proteins from the brain Nelly Khidekel, Scott B. Ficarro, Eric C. Peters, and Linda C. Hsieh-Wilson PMCID: PMC516536 Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation D. Borden Lacy, Darran J. Wigelsworth, Roman A. Melnyk, Stephen C. Harrison, and R. John Collier PMCID: PMC516539 Anticorrelated motions as a driving force in enzyme catalysis: The dehydrogenase reaction Jia Luo and Thomas C. Bruice PMCID: PMC516540 Crystal structure of a Baeyer–Villiger monooxygenase Enrico Malito, Andrea Alfieri, Marco W. Fraaije, and Andrea Mattevi PMCID: PMC516541 Incorporation of a single His residue by rational design enables thiol-ester hydrolysis by human glutathione transferase A1-1 Sofia Hederos, Kerstin S. Broo, Emma Jakobsson, Gerard J. Kleywegt, Bengt Mannervik, and Lars Baltzer PMCID: PMC516542 Universality in intermediary metabolism Eric Smith and Harold J. Morowitz PMCID: PMC516543 Inhibition of ghrelin action in vitro and in vivo by an RNA-Spiegelmer Steffen Helmling, Christian Maasch, Dirk Eulberg, Klaus Buchner, Werner Schröder, Christian Lange, Stefan Vonhoff, Britta Wlotzka, Matthias H. Tschöp, Stefan Rosewicz, and Sven Klussmann PMCID: PMC516544 Mapping activation and repression domains of the vnd/NK-2 homeodomain protein Alexander Stepchenko and Marshall Nirenberg PMCID: PMC516545 A trypanothione-dependent glyoxalase I with a prokaryotic ancestry in Leishmania major Tim J. Vickers, Neil Greig, and Alan H. Fairlamb PMCID: PMC516525 Biophysics Accelerated folding in the weak hydrophobic environment of a chaperonin cavity: Creation of an alternate fast folding pathway A. I. Jewett, A. Baumketner, and J.-E. Shea PMCID: PMC516546 Crystal structure of YjeQ from Thermotoga maritima contains a circularly permuted GTPase domain Dong Hae Shin, Yun Lou, Jaru Jancarik, Hisao Yokota, Rosalind Kim, and Sung-Hou Kim PMCID: PMC516547 Intracellular actin-based transport: How far you go depends on how often you switch Joseph Snider, Francis Lin, Neda Zahedi, Vladimir Rodionov, Clare C. Yu, and Steven P. Gross PMCID: PMC516548 From the Cover:
Robustness properties of circadian clock architectures Jörg Stelling, Ernst Dieter Gilles, and Francis J. Doyle, III PMCID: PMC516549 Coherent vibrational climbing in carboxyhemoglobin Cathie Ventalon, James M. Fraser, Marten H. Vos, Antigoni Alexandrou, Jean-Louis Martin, and Manuel Joffre PMCID: PMC516550 Cell Biology Nuclear body movement is determined by chromatin accessibility and dynamics Sabine M. Görisch, Malte Wachsmuth, Carina Ittrich, Christian P. Bacher, Karsten Rippe, and Peter Lichter PMCID: PMC516551 Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide Christopher Horst Lillig, Maria Elisabet Lönn, Mari Enoksson, Aristi Potamitou Fernandes, and Arne Holmgren PMCID: PMC516552 Type II platelet-activating factor-acetylhydrolase is essential for epithelial morphogenesis in Caenorhabditis elegans Takao Inoue, Asako Sugimoto, Yuka Suzuki, Masayuki Yamamoto, Masafumi Tsujimoto, Keizo Inoue, Junken Aoki, and Hiroyuki Arai PMCID: PMC516553 Tetra-O-methyl nordihydroguaiaretic acid induces growth arrest and cellular apoptosis by inhibiting Cdc2 and survivin expression Chih-Chuan Chang, Jonathan D. Heller, Jennifer Kuo, and Ru Chih C. Huang PMCID: PMC516554 Developmental Biology Proendocrine genes coordinate the pancreatic islet differentiation program in vitro Rosa Gasa, Caroline Mrejen, Nathaniel Leachman, Marc Otten, Michael Barnes, Juehu Wang, Swarup Chakrabarti, Raghavendra Mirmira, and Michael German PMCID: PMC516555 Evolution Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms Takashi Angata, Elliott H. Margulies, Eric D. Green, and Ajit Varki PMCID: PMC516556 Genetics Finding fusion genes resulting from chromosome rearrangement by analyzing the expressed sequence databases Yoonsoo Hahn, Tapan Kumar Bera, Kristen Gehlhaus, Ilan R. Kirsch, Ira H. Pastan, and Byungkook Lee PMCID: PMC516526 Chromosome healing through terminal deletions generated by de novo telomere additions in Saccharomyces cerevisiae Christopher D. Putnam, Vincent Pennaneach, and Richard D. Kolodner PMCID: PMC516557 Immunology Comparative immunopeptidomics of humans and their pathogens Sorin Istrail, Liliana Florea, Bjarni V. Halldórsson, Oliver Kohlbacher, Russell S. Schwartz, Von Bing Yap, Jonathan W. Yewdell, and Stephen L. Hoffman PMCID: PMC516558 Prototypic T cell receptor and CD4-like coreceptor are expressed by lymphocytes in the agnathan sea lamprey Zeev Pancer, Werner E. Mayer, Jan Klein, and Max D. Cooper PMCID: PMC516559 A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition Zarixia Zavala-Ruiz, Iwona Strug, Bruce D. Walker, Philip J. Norris, and Lawrence J. Stern PMCID: PMC516560 Medical Sciences From the Cover:
Ecological theory suggests that antimicrobial cycling will not reduce antimicrobial resistance in hospitals Carl T. Bergstrom, Monique Lo, and Marc Lipsitch PMCID: PMC516561 Nascent blood vessels in the skin arise from nestin-expressing hair-follicle cells Yasuyuki Amoh, Lingna Li, Meng Yang, A. R. Moossa, Kensei Katsuoka, Sheldon Penman, and Robert M. Hoffman PMCID: PMC516562 Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3) Therese Wiedmer, Ji Zhao, Lilin Li, Quansheng Zhou, Andrea Hevener, Jerrold M. Olefsky, Linda K. Curtiss, and Peter J. Sims PMCID: PMC516563 Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor Masao Kakoki, Nobuyuki Takahashi, J. Charles Jennette, and Oliver Smithies PMCID: PMC516527 EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib William Pao, Vincent Miller, Maureen Zakowski, Jennifer Doherty, Katerina Politi, Inderpal Sarkaria, Bhuvanesh Singh, Robert Heelan, Valerie Rusch, Lucinda Fulton, Elaine Mardis, Doris Kupfer, Richard Wilson, Mark Kris, and Harold Varmus PMCID: PMC516528 The leukemic fusion gene AML1-MDS1-EVI1 suppresses CEBPA in acute myeloid leukemia by activation of Calreticulin Daniel Helbling, Beatrice U. Mueller, Nikolai A. Timchenko, Anne Hagemeijer, Martine Jotterand, Sandrine Meyer-Monard, Andrew Lister, Janet D. Rowley, Barbara Huegli, Martin F. Fey, and Thomas Pabst PMCID: PMC516564 Microbiology Identification of a quinone-sensitive redox switch in the ArcB sensor kinase Roxana Malpica, Bernardo Franco, Claudia Rodriguez, Ohsuk Kwon, and Dimitris Georgellis PMCID: PMC516565 A Trim5-cyclophilin A fusion protein found in owl monkey kidney cells can restrict HIV-1 Sébastien Nisole, Clare Lynch, Jonathan P. Stoye, and Melvyn W. Yap PMCID: PMC516566 Neuroscience INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of Charles R. Gallistel Erik Stemmy PMCID: PMC516534 INAUGURAL ARTICLE by a Recently Elected Academy Member: The learning curve: Implications of a quantitative analysis Charles R. Gallistel, Stephen Fairhurst, and Peter Balsam PMCID: PMC516535 From the Cover:
Firing properties of dopamine neurons in freely moving dopamine-deficient mice: Effects of dopamine receptor activation and anesthesia Siobhan Robinson, David M. Smith, Sheri J. Y. Mizumori, and Richard D. Palmiter PMCID: PMC516529 Changes in connectivity profiles define functionally distinct regions in human medial frontal cortex H. Johansen-Berg, T. E. J. Behrens, M. D. Robson, I. Drobnjak, M. F. S. Rushworth, J. M. Brady, S. M. Smith, D. J. Higham, and P. M. Matthews PMCID: PMC516567 From the Cover:
Control of dendrite arborization by an Ig family member, dendrite arborization and synapse maturation 1 (Dasm1) Song-Hai Shi, Daniel N. Cox, Denan Wang, Lily Yeh Jan, and Yuh-Nung Jan PMCID: PMC516568 From the Cover:
The immunoglobulin family member dendrite arborization and synapse maturation 1 (Dasm1) controls excitatory synapse maturation Song-Hai Shi, Tong Cheng, Lily Yeh Jan, and Yuh-Nung Jan PMCID: PMC516569 Real-time imaging of single nerve cell apoptosis in retinal neurodegeneration M. Francesca Cordeiro, Li Guo, Vy Luong, Glen Harding, Wei Wang, Helen E. Jones, Stephen E. Moss, Adam M. Sillito, and Frederick W. Fitzke PMCID: PMC516570 Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles Edouard W. Khandjian, Marc-Etienne Huot, Sandra Tremblay, Laetitia Davidovic, Rachid Mazroui, and Barbara Bardoni PMCID: PMC516571 Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice Kunlin Jin, Veronica Galvan, Lin Xie, Xiao Ou Mao, Olivia F. Gorostiza, Dale E. Bredesen, and David A. Greenberg PMCID: PMC516572 Physiology Identification and proteomic profiling of exosomes in human urine Trairak Pisitkun, Rong-Fong Shen, and Mark A. Knepper PMCID: PMC516573 Plant Biology A transcriptional coactivator, AtGIF1, is involved in regulating leaf growth and morphology in Arabidopsis Jeong Hoe Kim and Hans Kende PMCID: PMC516574 A small CDC25 dual-specificity tyrosine-phosphatase isoform in Arabidopsis thaliana Isabelle Landrieu, Marco da Costa, Lieven De Veylder, Frédérique Dewitte, Klaas Vandepoele, Sahar Hassan, Jean-Michel Wieruszeski, Jean-Denis Faure, Marc Van Montagu, Dirk Inzé, and Guy Lippens PMCID: PMC516575 Population Biology From the Cover:
Fitness costs and benefits of novel herbicide tolerance in a noxious weed Regina S. Baucom and Rodney Mauricio PMCID: PMC516576 Vaccination and the theory of games Chris T. Bauch and David J. D. Earn PMCID: PMC516577 |
