| | This journal provides immediate access to some articles. Letters “Devolution” of bipedality Joachim Herz, Kym M. Boycott, and Jillian S. Parboosingh PMCID: PMC2396673 Genes and quadrupedal locomotion in humans Nicholas Humphrey, Stefan Mundlos, and Seval Türkmen PMCID: PMC2396709 This Week in PNAS Proc Natl Acad Sci U S A. 2008 May 27; 105(21): 7339–7340. doi: 10.1073/iti2108105.PMCID: PMC2396718 Commentaries The shortest wire Anne-Frances Miller PMCID: PMC2396719 Rhodopsin's active state is frozen like a DEER in the headlights Thomas Huber and Thomas P. Sakmar PMCID: PMC2396688 The molecular intersection of brassinosteroid-regulated growth and flowering in Arabidopsis Steven D. Clouse PMCID: PMC2396720 Physical Sciences Chemistry From the Cover:
Swapping metals in Fe- and Mn-dependent dioxygenases: Evidence for oxygen activation without a change in metal redox state Joseph P. Emerson, Elena G. Kovaleva, Erik R. Farquhar, John D. Lipscomb, and Lawrence Que, Jr. PMCID: PMC2396700 Synthesis of linked carbon monolayers: Films, balloons, tubes, and pleated sheets Mitchell J. Schultz, Xiaoyu Zhang, Sakulsuk Unarunotai, Dahl-Young Khang, Qing Cao, Congjun Wang, Changhui Lei, Scott MacLaren, Julio A. N. T. Soares, Ivan Petrov, Jeffrey S. Moore, and John A. Rogers PMCID: PMC2396712 Synthesis and bioassay of improved mosquito repellents predicted from chemical structure Alan R. Katritzky, Zuoquan Wang, Svetoslav Slavov, Maia Tsikolia, Dimitar Dobchev, Novruz G. Akhmedov, C. Dennis Hall, Ulrich R. Bernier, Gary G. Clark, and Kenneth J. Linthicum PMCID: PMC2396717 Atomic interactions of neonicotinoid agonists with AChBP: Molecular recognition of the distinctive electronegative pharmacophore Todd T. Talley, Michal Harel, Ryan E. Hibbs, Zoran Radić, Motohiro Tomizawa, John E. Casida, and Palmer Taylor PMCID: PMC2396707 Engineering Hydrodynamic metamaterials: Microfabricated arrays to steer, refract, and focus streams of biomaterials Keith J. Morton, Kevin Loutherback, David W. Inglis, Ophelia K. Tsui, James C. Sturm, Stephen Y. Chou, and Robert H. Austin PMCID: PMC2396696 Environmental Sciences Acidity enhances the formation of a persistent ozonide at aqueous ascorbate/ozone gas interfaces Shinichi Enami, M. R. Hoffmann, and A. J. Colussi PMCID: PMC2386772 Simultaneous observations of aerosol–cloud–albedo interactions with three stacked unmanned aerial vehicles G. C. Roberts, M. V. Ramana, C. Corrigan, D. Kim, and V. Ramanathan PMCID: PMC2396670 Geology On the coevolution of Ediacaran oceans and animals Yanan Shen, Tonggang Zhang, and Paul F. Hoffman PMCID: PMC2375388 Geophysics Crystal structure and thermoelastic properties of (Mg0.91Fe0.09)SiO3 postperovskite up to 135 GPa and 2,700 K Sang-Heon Shim, Krystle Catalli, Justin Hustoft, Atsushi Kubo, Vitali B. Prakapenka, Wendel A. Caldwell, and Martin Kunz PMCID: PMC2396716 Biological Sciences Applied Biological Sciences Perturbational profiling of nanomaterial biologic activity Stanley Y. Shaw, Elizabeth C. Westly, Mikael J. Pittet, Aravind Subramanian, Stuart L. Schreiber, and Ralph Weissleder PMCID: PMC2396702 Microbial production of plant benzylisoquinoline alkaloids Hiromichi Minami, Ju-Sung Kim, Nobuhiro Ikezawa, Tomoya Takemura, Takane Katayama, Hidehiko Kumagai, and Fumihiko Sato PMCID: PMC2396723 Biochemistry From the Cover:
Swapping metals in Fe- and Mn-dependent dioxygenases: Evidence for oxygen activation without a change in metal redox state Joseph P. Emerson, Elena G. Kovaleva, Erik R. Farquhar, John D. Lipscomb, and Lawrence Que, Jr. PMCID: PMC2396700 Structural basis of actin recognition and arginine ADP-ribosylation by Clostridium perfringens ι-toxin Hideaki Tsuge, Masahiro Nagahama, Masataka Oda, Shinobu Iwamoto, Hiroko Utsunomiya, Victor E. Marquez, Nobuhiko Katunuma, Mugio Nishizawa, and Jun Sakurai PMCID: PMC2387182 Biochemical visualization of cell surface molecular clustering in living cells Norihiro Kotani, Jianguo Gu, Tomoya Isaji, Keiko Udaka, Naoyuki Taniguchi, and Koichi Honke PMCID: PMC2396715 Structure of the membrane proximal oxidoreductase domain of human Steap3, the dominant ferrireductase of the erythroid transferrin cycle Anoop K. Sendamarai, Robert S. Ohgami, Mark D. Fleming, and C. Martin Lawrence PMCID: PMC2396704 Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13 Wenjing Cao, Sriram Krishnaswamy, Rodney M. Camire, Peter J. Lenting, and X. Long Zheng PMCID: PMC2396690 Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol Mamoru Komatsu, Muneya Tsuda, Satoshi Ōmura, Hideaki Oikawa, and Haruo Ikeda PMCID: PMC2387273 A rationally engineered misacylating aminoacyl-tRNA synthetase Timothy L. Bullock, Annia Rodríguez-Hernández, Eleonora M. Corigliano, and John J. Perona PMCID: PMC2396676 Biophysics Hydrodynamic metamaterials: Microfabricated arrays to steer, refract, and focus streams of biomaterials Keith J. Morton, Kevin Loutherback, David W. Inglis, Ophelia K. Tsui, James C. Sturm, Stephen Y. Chou, and Robert H. Austin PMCID: PMC2396696 From the Cover:
High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation Christian Altenbach, Ana Karin Kusnetzow, Oliver P. Ernst, Klaus Peter Hofmann, and Wayne L. Hubbell PMCID: PMC2396682 Complementary dimerization of microtubule-associated tau protein: Implications for microtubule bundling and tau-mediated pathogenesis Kenneth J. Rosenberg, Jennifer L. Ross, H. Eric Feinstein, Stuart C. Feinstein, and Jacob Israelachvili PMCID: PMC2396711 Structure of TRPV1 channel revealed by electron cryomicroscopy Vera Y. Moiseenkova-Bell, Lia A. Stanciu, Irina I. Serysheva, Ben J. Tobe, and Theodore G. Wensel PMCID: PMC2396679 Entropic contributions and the influence of the hydrophobic environment in promiscuous protein–protein association Chia-en A. Chang, William A. McLaughlin, Riccardo Baron, Wei Wang, and J. Andrew McCammon PMCID: PMC2391134 Paired β-sheet structure of an Aβ(1-40) amyloid fibril revealed by electron microscopy Carsten Sachse, Marcus Fändrich, and Nikolaus Grigorieff PMCID: PMC2396686 Cell Biology Chemicals that modulate stem cell differentiation Ki-Chul Hwang, Ji Young Kim, Woochul Chang, Dae-Sung Kim, Soyeon Lim, Sang-Moon Kang, Byeong-Wook Song, Hye-Yeong Ha, Yong Joon Huh, In-Geol Choi, Dong-Youn Hwang, Heesang Song, Yangsoo Jang, Namsik Chung, Sung-Hou Kim, and Dong-Wook Kim PMCID: PMC2396687 Developmental Biology Transcription factor Ap2δ associates with Ash2l and ALR, a trithorax family histone methyltransferase, to activate Hoxc8 transcription Cheryl C. Tan, K. V. Sindhu, SiDe Li, Hitomi Nishio, Jason Z. Stoller, Kimihiko Oishi, Sahitya Puttreddy, Tamara J. Lee, Jonathan A. Epstein, Martin J. Walsh, and Bruce D. Gelb PMCID: PMC2396708 Evolution On the coevolution of Ediacaran oceans and animals Yanan Shen, Tonggang Zhang, and Paul F. Hoffman PMCID: PMC2375388 The evolution of courtship behaviors through the origination of a new gene in Drosophila Hongzheng Dai, Ying Chen, Sidi Chen, Qiyan Mao, David Kennedy, Patrick Landback, Adam Eyre-Walker, Wei Du, and Manyuan Long PMCID: PMC2396706 The evolution of imperfect floral mimicry Nicolas J. Vereecken and Florian P. Schiestl PMCID: PMC2396721 Virulence-transmission trade-offs and population divergence in virulence in a naturally occurring butterfly parasite Jacobus C. de Roode, Andrew J. Yates, and Sonia Altizer PMCID: PMC2396697 From the Cover:
Reproductive mode plasticity: Aquatic and terrestrial oviposition in a treefrog Justin Charles Touchon and Karen Michelle Warkentin PMCID: PMC2396680 Modularity of stress response evolution Amoolya H. Singh, Denise M. Wolf, Peggy Wang, and Adam P. Arkin PMCID: PMC2396705 Genetics Social interaction-mediated lifespan extension of Drosophila Cu/Zn superoxide dismutase mutants Hongyu Ruan and Chun-Fang Wu PMCID: PMC2396722 Functional analysis of the Arabidopsis centromere by T-DNA insertion-induced centromere breakage Minoru Murata, Etsuko Yokota, Fukashi Shibata, and Kazunari Kashihara PMCID: PMC2396678 MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression Frank E. Erfurth, Relja Popovic, Jolanta Grembecka, Tomasz Cierpicki, Catherine Theisler, Zhen-Biao Xia, Tara Stuart, Manuel O. Diaz, John H. Bushweller, and Nancy J. Zeleznik-Le PMCID: PMC2396713 Deletion of a gene encoding an amino acid transporter in the midgut membrane causes resistance to a Bombyx parvo-like virus Katsuhiko Ito, Kurako Kidokoro, Hideki Sezutsu, Junko Nohata, Kimiko Yamamoto, Isao Kobayashi, Keiro Uchino, Andrew Kalyebi, Ryokitsu Eguchi, Wajiro Hara, Toshiki Tamura, Susumu Katsuma, Toru Shimada, Kazuei Mita, and Keiko Kadono-Okuda PMCID: PMC2391135 Immunology From the Cover:
Hyper innate responses in neonates lead to increased morbidity and mortality after infection Jie Zhao, Kwang Dong Kim, Xuanming Yang, Sogyong Auh, Yang-Xin Fu, and Hong Tang PMCID: PMC2396698 Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1 Saebyeol Jang, Keith W. Kelley, and Rodney W. Johnson PMCID: PMC2396685 Medical Sciences Chronic sodium nitrite therapy augments ischemia-induced angiogenesis and arteriogenesis Dinesh Kumar, Billy G. Branch, Christopher B. Pattillo, Jay Hood, Stephen Thoma, Stephen Simpson, Sandra Illum, Neeraj Arora, John H. Chidlow, Jr., Will Langston, Xinjun Teng, David J. Lefer, Rakesh P. Patel, and Christopher G. Kevil PMCID: PMC2396555 Overcoming retinoic acid-resistance of mammary carcinomas by diverting retinoic acid from PPARβ/δ to RAR Thaddeus T. Schug, Daniel C. Berry, Illia A. Toshkov, Le Cheng, Alexander Yu Nikitin, and Noa Noy PMCID: PMC2396692 Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection Brandon F. Keele, Elena E. Giorgi, Jesus F. Salazar-Gonzalez, Julie M. Decker, Kimmy T. Pham, Maria G. Salazar, Chuanxi Sun, Truman Grayson, Shuyi Wang, Hui Li, Xiping Wei, Chunlai Jiang, Jennifer L. Kirchherr, Feng Gao, Jeffery A. Anderson, Li-Hua Ping, Ronald Swanstrom, Georgia D. Tomaras, William A. Blattner, Paul A. Goepfert, J. Michael Kilby, Michael S. Saag, Eric L. Delwart, Michael P. Busch, Myron S. Cohen, David C. Montefiori, Barton F. Haynes, Brian Gaschen, Gayathri S. Athreya, Ha Y. Lee, Natasha Wood, Cathal Seoighe, Alan S. Perelson, Tanmoy Bhattacharya, Bette T. Korber, Beatrice H. Hahn, and George M. Shaw PMCID: PMC2387184 Microbiology Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility Jessica A. Belser, Ola Blixt, Li-Mei Chen, Claudia Pappas, Taronna R. Maines, Neal Van Hoeven, Ruben Donis, Julia Busch, Ryan McBride, James C. Paulson, Jacqueline M. Katz, and Terrence M. Tumpey PMCID: PMC2396559 Nitrogen fixation island and rhizosphere competence traits in the genome of root-associated Pseudomonas stutzeri A1501 Yongliang Yan, Jian Yang, Yuetan Dou, Ming Chen, Shuzhen Ping, Junping Peng, Wei Lu, Wei Zhang, Ziying Yao, Hongquan Li, Wei Liu, Sheng He, Lizhao Geng, Xiaobing Zhang, Fan Yang, Haiying Yu, Yuhua Zhan, Danhua Li, Zhanglin Lin, Yiping Wang, Claudine Elmerich, Min Lin, and Qi Jin PMCID: PMC2396677 Neuroscience Cdk5-mediated regulation of the PIKE-A-Akt pathway and glioblastoma cell invasion Ren Liu, Bo Tian, Marla Gearing, Stephen Hunter, Keqiang Ye, and Zixu Mao PMCID: PMC2396674 Neuronal avalanches organize as nested theta- and beta/gamma-oscillations during development of cortical layer 2/3 Elakkat D. Gireesh and Dietmar Plenz PMCID: PMC2396689 Neuroprotection via matrix-trophic coupling between cerebral endothelial cells and neurons Shuzhen Guo, Woo Jean Kim, Josephine Lok, Sun-Ryung Lee, Elaine Besancon, Bing-Hao Luo, Monique F. Stins, Xiaoying Wang, Shoukat Dedhar, and Eng H. Lo PMCID: PMC2396701 In vivo two-photon voltage-sensitive dye imaging reveals top-down control of cortical layers 1 and 2 during wakefulness B. Kuhn, W. Denk, and R. M. Bruno PMCID: PMC2396672 Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice Koji Yamanaka, Severine Boillee, Elizabeth A. Roberts, Michael L. Garcia, Melissa McAlonis-Downes, Oliver R. Mikse, Don W. Cleveland, and Lawrence S. B. Goldstein PMCID: PMC2396671 Modulation of auditory processing by cortico-cortical feed-forward and feedback projections Jie Tang and Nobuo Suga PMCID: PMC2396714 Pharmacology Atomic interactions of neonicotinoid agonists with AChBP: Molecular recognition of the distinctive electronegative pharmacophore Todd T. Talley, Michal Harel, Ryan E. Hibbs, Zoran Radić, Motohiro Tomizawa, John E. Casida, and Palmer Taylor PMCID: PMC2396707 Physiology Synergistic upregulation of erythropoietin receptor (EPO-R) expression by sense and antisense EPO-R transcripts in the canine lung Quiyang Zhang, Jianning Zhang, Orson W. Moe, and Connie C. W. Hsia PMCID: PMC2396693 Plant Biology From the Cover:
Modulation of brassinosteroid-regulated gene expression by jumonji domain-containing proteins ELF6 and REF6 in Arabidopsis Xiaofei Yu, Li Li, Lei Li, Michelle Guo, Joanne Chory, and Yanhai Yin PMCID: PMC2396691 |
