| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 July 3; 104(27): 11121–11122. doi: 10.1073/iti2707104.PMCID: PMC2040860 Commentaries What can we learn about fertilization from cystic fibrosis? Harvey M. Florman, Melissa K. Jungnickel, and Keith A. Sutton PMCID: PMC2040861 Stuffing a virus with DNA: Dissecting viral genome packaging Mark C. Williams PMCID: PMC2040862 Profile Profile of David L. Denlinger Kaspar Mossman PMCID: PMC2040863 Physical Sciences Applied Mathematics Defining functional distance using manifold embeddings of gene ontology annotations Gilad Lerman and Boris E. Shakhnovich PMCID: PMC2040899 Applied Physical Sciences From the Cover:
A model of Internet topology using k-shell decomposition Shai Carmi, Shlomo Havlin, Scott Kirkpatrick, Yuval Shavitt, and Eran Shir PMCID: PMC1896135 Ductile crystalline–amorphous nanolaminates Yinmin Wang, Ju Li, Alex V. Hamza, and Troy W. Barbee, Jr. PMCID: PMC1899185 Electron tunneling through alkanedithiol self-assembled monolayers in large-area molecular junctions Hylke B. Akkerman, Ronald C. G. Naber, Bert Jongbloed, Paul A. van Hal, Paul W. M. Blom, Dago M. de Leeuw, and Bert de Boer PMCID: PMC1899190 Chemistry Reorientional dynamics of water molecules in anionic hydration shells Damien Laage and James T. Hynes PMCID: PMC2040870 Colloids with high-definition surface structures Hsien-Yeh Chen, Jean-Marie Rouillard, Erdogan Gulari, and Joerg Lahann PMCID: PMC2040871 Single-molecule observation of DNA charge transfer Tadao Takada, Mamoru Fujitsuka, and Tetsuro Majima PMCID: PMC2040872 Recognition of trimethyllysine by a chromodomain is not driven by the hydrophobic effect Robert M. Hughes, Kimberly R. Wiggins, Sepideh Khorasanizadeh, and Marcey L. Waters PMCID: PMC2040873 Small-molecule-mediated rescue of protein function by an inducible proteolytic shunt Matthew R. Pratt, Edmund C. Schwartz, and Tom W. Muir PMCID: PMC2040878 Mathematics Computing the distribution of the maximum in balls-and-boxes problems with application to clusters of disease cases Warren J. Ewens and Herbert S. Wilf PMCID: PMC2040874 Physics Asymmetric redistribution of GABA receptors during GABA gradient sensing by nerve growth cones analyzed by single quantum dot imaging Cédric Bouzigues, Mathieu Morel, Antoine Triller, and Maxime Dahan PMCID: PMC2040885 Biological Sciences Agricultural Sciences Diversity enhances agricultural productivity via rhizosphere phosphorus facilitation on phosphorus-deficient soils Long Li, Shu-Min Li, Jian-Hao Sun, Li-Li Zhou, Xing-Guo Bao, Hong-Gang Zhang, and Fu-Suo Zhang PMCID: PMC1899187 Applied Biological Sciences Dispersing biofilms with engineered enzymatic bacteriophage Timothy K. Lu and James J. Collins PMCID: PMC1899193 From the Cover:
Measurement of 7,8-dihydro-8-oxo-2′-deoxyguanosine metabolism in MCF-7 cells at low concentrations using accelerator mass spectrometry Sang Soo Hah, Janna M. Mundt, Hyung M. Kim, Rhoda A. Sumbad, Kenneth W. Turteltaub, and Paul T. Henderson PMCID: PMC2040877 Biochemistry INAUGURAL ARTICLE by a Recently Elected Academy Member: Collaboration between the ClpB AAA+ remodeling protein and the DnaK chaperone system Shannon M. Doyle, Joel R. Hoskins, and Sue Wickner PMCID: PMC2040865 Single-molecule observation of DNA charge transfer Tadao Takada, Mamoru Fujitsuka, and Tetsuro Majima PMCID: PMC2040872 Small-molecule-mediated rescue of protein function by an inducible proteolytic shunt Matthew R. Pratt, Edmund C. Schwartz, and Tom W. Muir PMCID: PMC2040878 Evolution of Na,K-ATPase βm-subunit into a coregulator of transcription in placental mammals Nikolay B. Pestov, Nisar Ahmad, Tatiana V. Korneenko, Hao Zhao, Rossen Radkov, Danièle Schaer, Sophie Roy, Stéphanie Bibert, Käthi Geering, and Nikolai N. Modyanov PMCID: PMC2040879 PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor Sulfolipid-1 Pawan Kumar, Michael W. Schelle, Madhulika Jain, Fiona L. Lin, Christopher J. Petzold, Michael D. Leavell, Julie A. Leary, Jeffery S. Cox, and Carolyn R. Bertozzi PMCID: PMC2040880 Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: Identity with Rinderknecht's enzyme Y Richárd Szmola and Miklós Sahin-Tóth PMCID: PMC2040881 Structures of the thermophilic F1-ATPase ε subunit suggesting ATP-regulated arm motion of its C-terminal domain in F1 Hiromasa Yagi, Nobumoto Kajiwara, Hideaki Tanaka, Tomitake Tsukihara, Yasuyuki Kato-Yamada, Masasuke Yoshida, and Hideo Akutsu PMCID: PMC2040882 Charcot–Marie–Tooth disease-associated mutant tRNA synthetases linked to altered dimer interface and neurite distribution defect Leslie A. Nangle, Wei Zhang, Wei Xie, Xiang-Lei Yang, and Paul Schimmel PMCID: PMC2040883 Biophysics Recognition of trimethyllysine by a chromodomain is not driven by the hydrophobic effect Robert M. Hughes, Kimberly R. Wiggins, Sepideh Khorasanizadeh, and Marcey L. Waters PMCID: PMC2040873 From the Cover: Ionic effects on viral DNA packaging and portal motor function in bacteriophage ![[var phi]](corehtml/pmc/pmcents/x03C6.gif) 29 Derek N. Fuller, John Peter Rickgauer, Paul J. Jardine, Shelley Grimes, Dwight L. Anderson, and Douglas E. Smith PMCID: PMC2040884 Asymmetric redistribution of GABA receptors during GABA gradient sensing by nerve growth cones analyzed by single quantum dot imaging Cédric Bouzigues, Mathieu Morel, Antoine Triller, and Maxime Dahan PMCID: PMC2040885 Protein folding and unfolding studied at atomic resolution by fast two-dimensional NMR spectroscopy Paul Schanda, Vincent Forge, and Bernhard Brutscher PMCID: PMC2040886 Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: A possible general mechanism for familial ALS Lucia Banci, Ivano Bertini, Armando Durazo, Stefania Girotto, Edith Butler Gralla, Manuele Martinelli, Joan Selverstone Valentine, Miguela Vieru, and Julian P. Whitelegge PMCID: PMC1899188 Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation Jennifer M. Kavran, Sarath Gundllapalli, Patrick O'Donoghue, Markus Englert, Dieter Söll, and Thomas A. Steitz PMCID: PMC2040888 Cell Biology Csrp1 regulates dynamic cell movements of the mesendoderm and cardiac mesoderm through interactions with Dishevelled and Diversin Kota Y. Miyasaka, Yasuyuki S. Kida, Takayuki Sato, Mari Minami, and Toshihiko Ogura PMCID: PMC2040889 The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch Andrew Oberst, Martina Malatesta, Rami I. Aqeilan, Mario Rossi, Paolo Salomoni, Rodolfo Murillas, Prashant Sharma, Michael R. Kuehn, Moshe Oren, Carlo M. Croce, Francesca Bernassola, and Gerry Melino PMCID: PMC2040890 Bcl-2 is the target of a UV-inducible apoptosis switch and a node for UV signaling Dejan Knezevic, Wengeng Zhang, Patrick J. Rochette, and Douglas E. Brash PMCID: PMC2040891 Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum Shigeki Yoshiura, Toshiyuki Ohtsuka, Yoshiko Takenaka, Hiroki Nagahara, Kenichi Yoshikawa, and Ryoichiro Kageyama PMCID: PMC1899192 Developmental Biology Hyaluronic acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells Sharon Gerecht, Jason A. Burdick, Lino S. Ferreira, Seth A. Townsend, Robert Langer, and Gordana Vunjak-Novakovic PMCID: PMC2040893 Life cycle transcriptome of the malaria mosquito Anopheles gambiae and comparison with the fruitfly Drosophila melanogaster Anastasios C. Koutsos, Claudia Blass, Stephan Meister, Sabine Schmidt, Robert M. MacCallum, Marcelo B. Soares, Frank H. Collins, Vladimir Benes, Evgeny Zdobnov, Fotis C. Kafatos, and George K. Christophides PMCID: PMC2040894 Six proteins regulate the activation of Myf5 expression in embryonic mouse limbs Julien Giordani, Lola Bajard, Josiane Demignon, Philippe Daubas, Margaret Buckingham, and Pascal Maire PMCID: PMC2040895 Zebrafish model for human long QT syndrome Rima Arnaout, Tania Ferrer, Jan Huisken, Kenneth Spitzer, Didier Y. R. Stainier, Martin Tristani-Firouzi, and Neil C. Chi PMCID: PMC2040896 Essential roles of inhibin beta A in mouse epididymal coiling Jessica Tomaszewski, Avenel Joseph, Denise Archambeault, and Humphrey Hung-Chang Yao PMCID: PMC2040897 Enteroendocrine precursors differentiate independently of Wnt and form serotonin expressing adenomas in response to active β-catenin Yang Wang, Maryann Giel-Moloney, Guido Rindi, and Andrew B. Leiter PMCID: PMC2040898 Evolution Defining functional distance using manifold embeddings of gene ontology annotations Gilad Lerman and Boris E. Shakhnovich PMCID: PMC2040899 Recent LTR retrotransposon insertion contrasts with waves of non-LTR insertion since speciation in Drosophila melanogaster Casey M. Bergman and Douda Bensasson PMCID: PMC2040900 Genetics Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults Swee Lay Thein, Stephan Menzel, Xu Peng, Steve Best, Jie Jiang, James Close, Nicholas Silver, Ageliki Gerovasilli, Chen Ping, Masao Yamaguchi, Karin Wahlberg, Pinar Ulug, Tim D. Spector, Chad Garner, Fumihiko Matsuda, Martin Farrall, and Mark Lathrop PMCID: PMC2040901 Oligonucleotide transformation of yeast reveals mismatch repair complexes to be differentially active on DNA replication strands Yoke W. Kow, Gaobin Bao, Jason W. Reeves, Sue Jinks-Robertson, and Gray F. Crouse PMCID: PMC2040902 The yeast DNA damage checkpoint proteins control a cytoplasmic response to DNA damage Farokh Dotiwala, Julian Haase, Ayelet Arbel-Eden, Kerry Bloom, and James E. Haber PMCID: PMC1896138 Ceramide transfer protein function is essential for normal oxidative stress response and lifespan Raghavendra Pralhada Rao, Changqing Yuan, Jeremy C. Allegood, Satinder S. Rawat, Michael Beth Edwards, Xin Wang, Alfred H. Merrill, Jr., Usha Acharya, and Jairaj K. Acharya PMCID: PMC1899189 Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing Maria Simarro, David Mauger, Kirsten Rhee, Miguel A. Pujana, Nancy L. Kedersha, Satoshi Yamasaki, Michael E. Cusick, Marc Vidal, Mariano A. Garcia-Blanco, and Paul Anderson PMCID: PMC2040905 Conserved noncoding genomic sequences associated with a flowering-time quantitative trait locus in maize Silvio Salvi, Giorgio Sponza, Michele Morgante, Dwight Tomes, Xiaomu Niu, Kevin A. Fengler, Robert Meeley, Evgueni V. Ananiev, Sergei Svitashev, Edward Bruggemann, Bailin Li, Christine F. Hainey, Slobodanka Radovic, Giusi Zaina, J.-Antoni Rafalski, Scott V. Tingey, Guo-Hua Miao, Ronald L. Phillips, and Roberto Tuberosa PMCID: PMC2040906 Immunology T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses Tatyana Tarasenko, Hemanta K. Kole, Anthony W. Chi, Margaret M. Mentink-Kane, Thomas A. Wynn, and Silvia Bolland PMCID: PMC2040907 Medical Sciences Computing the distribution of the maximum in balls-and-boxes problems with application to clusters of disease cases Warren J. Ewens and Herbert S. Wilf PMCID: PMC2040874 Induction of Cullin 7 by DNA damage attenuates p53 function Peter Jung, Berlinda Verdoodt, Aaron Bailey, John R. Yates, III, Antje Menssen, and Heiko Hermeking PMCID: PMC2040908 Pathological role of osteoclast costimulation in arthritis-induced bone loss Sae Ochi, Masahiro Shinohara, Kojiro Sato, Hans-Jürgen Gober, Takako Koga, Tatsuhiko Kodama, Toshiyuki Takai, Nobuyuki Miyasaka, and Hiroshi Takayanagi PMCID: PMC2040909 Let-7 expression defines two differentiation stages of cancer Scott Shell, Sun-Mi Park, Amir Reza Radjabi, Robert Schickel, Emily O. Kistner, David A. Jewell, Christine Feig, Ernst Lengyel, and Marcus E. Peter PMCID: PMC2040910 Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q− syndrome patients Andrea Pellagatti, Martin Jädersten, Ann-Mari Forsblom, Helen Cattan, Birger Christensson, Emma K. Emanuelsson, Mats Merup, Lars Nilsson, Jan Samuelsson, Birgitta Sander, James S. Wainscoat, Jacqueline Boultwood, and Eva Hellström-Lindberg PMCID: PMC1892786 Genetic targeting of the kinase activity of the Met receptor in cancer cells Sabrina Arena, Alberto Pisacane, Massimiliano Mazzone, Paolo Maria Comoglio, and Alberto Bardelli PMCID: PMC2040912 The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted Sebastien Bonnet, Gael Rochefort, Gopinath Sutendra, Stephen L. Archer, Alois Haromy, Linda Webster, Kyoko Hashimoto, Sandra N. Bonnet, and Evangelos D. Michelakis PMCID: PMC1903339 Microbiology INAUGURAL ARTICLE by a Recently Elected Academy Member: Regulatory small RNAs circumvent the conventional quorum sensing pathway in pandemic Vibrio choleraeBrian K. Hammer and Bonnie L. Bassler PMCID: PMC1888797 A previously unknown reovirus of bat origin is associated with an acute respiratory disease in humans Kaw Bing Chua, Gary Crameri, Alex Hyatt, Meng Yu, Mohd Rosli Tompang, Juliana Rosli, Jennifer McEachern, Sandra Crameri, Verasingam Kumarasamy, Bryan T. Eaton, and Lin-Fa Wang PMCID: PMC1899191 Mechanisms of host cell exit by the intracellular bacterium Chlamydia Kevin Hybiske and Richard S. Stephens PMCID: PMC2040915 Global patterns in bacterial diversity Catherine A. Lozupone and Rob Knight PMCID: PMC2040916 Neuroscience From the Cover:
Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice Tohru Kitada, Antonio Pisani, Douglas R. Porter, Hiroo Yamaguchi, Anne Tscherter, Giuseppina Martella, Paola Bonsi, Chen Zhang, Emmanuel N. Pothos, and Jie Shen PMCID: PMC1890561 Targeted dendrotomy reveals active and passive contributions of the dendritic tree to synaptic integration and neuronal output John M. Bekkers and Michael Häusser PMCID: PMC2040918 Selective control of cortical axonal spikes by a slowly inactivating K+ current Yousheng Shu, Yuguo Yu, Jing Yang, and David A. McCormick PMCID: PMC2040919 Electrical stimulation of the rostral medial prefrontal cortex in rabbits inhibits the expression of conditioned eyelid responses but not their acquisition Rocío Leal-Campanario, Alfonso Fairén, José M. Delgado-García, and Agnès Gruart PMCID: PMC1899194 Interactive effects of age and estrogen on cognition and pyramidal neurons in monkey prefrontal cortex Jiandong Hao, Peter R. Rapp, William G. M. Janssen, Wendy Lou, Bill L. Lasley, Patrick R. Hof, and John H. Morrison PMCID: PMC2040921 Hippocampal long-term depression mediates acute stress-induced spatial memory retrieval impairment Tak Pan Wong, John G. Howland, Julie M. Robillard, Yuan Ge, Wayne Yu, Andrea K. Titterness, Karen Brebner, Lidong Liu, Joanne Weinberg, Brian R. Christie, Anthony G. Phillips, and Yu Tian Wang PMCID: PMC2040922 Dual personality of GABA/glycine-mediated depolarizations in immature spinal cord Céline Jean-Xavier, George Z. Mentis, Michael J. O'Donovan, Daniel Cattaert, and Laurent Vinay PMCID: PMC2040923 Neural correlates of attentional expertise in long-term meditation practitioners J. A. Brefczynski-Lewis, A. Lutz, H. S. Schaefer, D. B. Levinson, and R. J. Davidson PMCID: PMC1903340 Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice Mansuo L. Hayashi, B. S. Shankaranarayana Rao, Jin-Soo Seo, Han-Saem Choi, Bridget M. Dolan, Se-Young Choi, Sumantra Chattarji, and Susumu Tonegawa PMCID: PMC1899186 Physiology INAUGURAL ARTICLE by a Recently Elected Academy Member: Up-regulation of heat shock proteins is essential for cold survival during insect diapause Joseph P. Rinehart, Aiqing Li, George D. Yocum, Rebecca M. Robich, Scott A. L. Hayward, and David L. Denlinger PMCID: PMC2040864 Plant Biology From the Cover:
Enhanced plant tolerance to iron starvation by functional substitution of chloroplast ferredoxin with a bacterial flavodoxin Vanesa B. Tognetti, Matias D. Zurbriggen, Eligio N. Morandi, María F. Fillat, Estela M. Valle, Mohammad-Reza Hajirezaei, and Néstor Carrillo PMCID: PMC2040926 Dual specificities of the glyoxysomal/peroxisomal processing protease Deg15 in higher plants Michael Helm, Carsten Lück, Jakob Prestele, Georg Hierl, Pitter F. Huesgen, Thomas Fröhlich, Georg J. Arnold, Iwona Adamska, Angelika Görg, Friedrich Lottspeich, and Christine Gietl PMCID: PMC2040927 Corrections Correction for Zhou et al., Destruction of long-range interactions by a single mutation in lysozyme PMCID: PMC2040928 Corrects: Ruhong Zhou, et al. Destruction of long-range interactions by a single mutation in lysozyme. Proc Natl Acad Sci U S A. 2007 April 3; 104(14): 5824–5829. Correction for Liu and Ochman, Stepwise formation of the bacterial flagellar system PMCID: PMC2040929 Corrects: Renyi Liu, et al. Stepwise formation of the bacterial flagellar system. Proc Natl Acad Sci U S A. 2007 April 24; 104(17): 7116–7121. |
