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Volume 103(44);  October 31, 2006
This Week in PNAS
In This Issue
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16059–16060. doi: 10.1073/iti4406103.
PMCID: PMC1637534
Commentaries
Skirting the transition state, a new paradigm in reaction rate theory
Joel M. Bowman
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16061–16062. Published online 2006 October 23. doi: 10.1073/pnas.0607810103.
PMCID: PMC1637535
Discovery of principles of nature from mathematical modeling of DNA microarray data
Orly Alter
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16063–16064. Published online 2006 October 23. doi: 10.1073/pnas.0607650103.
PMCID: PMC1637536
Profile
Profile of Gene E. Robinson
Nick Zagorski
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16065–16067. Published online 2006 October 25. doi: 10.1073/pnas.0608392103.
PMCID: PMC1637537
Physical Sciences
Applied Physical Sciences
Acceleration of the recognition rate between grafted ligands and receptors with magnetic forces
J. Baudry, C. Rouzeau, C. Goubault, C. Robic, L. Cohen-Tannoudji, A. Koenig, E. Bertrand, and J. Bibette
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16076–16078. Published online 2006 October 18. doi: 10.1073/pnas.0607991103.
PMCID: PMC1637538
Chemistry
From the Cover:
Photodissociation of acetaldehyde as a second example of the roaming mechanism
P. L. Houston and S. H. Kable
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16079–16082. Published online 2006 October 17. doi: 10.1073/pnas.0604441103.
PMCID: PMC1637539
Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals
Gil Goobes, Rivka Goobes, Ora Schueler-Furman, David Baker, Patrick S. Stayton, and Gary P. Drobny
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16083–16088. Published online 2006 October 23. doi: 10.1073/pnas.0607193103.
PMCID: PMC1637540
The limitations on organic detection in Mars-like soils by thermal volatilization–gas chromatography–MS and their implications for the Viking results
Rafael Navarro-González, Karina F. Navarro, José de la Rosa, Enrique Iñiguez, Paola Molina, Luis D. Miranda, Pedro Morales, Edith Cienfuegos, Patrice Coll, François Raulin, Ricardo Amils, and Christopher P. McKay
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16089–16094. Published online 2006 October 23. doi: 10.1073/pnas.0604210103.
PMCID: PMC1621051
Engineering
Anisotropic mechanosensing by mesenchymal stem cells
Kyle Kurpinski, Julia Chu, Craig Hashi, and Song Li
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16095–16100. Published online 2006 October 23. doi: 10.1073/pnas.0604182103.
PMCID: PMC1637542
Physics
Liquid–crystalline aqueous clay suspensions
Laurent J. Michot, Isabelle Bihannic, Solange Maddi, Sérgio S. Funari, Christophe Baravian, Pierre Levitz, and Patrick Davidson
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16101–16104. Published online 2006 October 23. doi: 10.1073/pnas.0605201103.
PMCID: PMC1637543
Breaking resolution limits in ultrafast electron diffraction and microscopy
Peter Baum and Ahmed H. Zewail
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16105–16110. Published online 2006 October 20. doi: 10.1073/pnas.0607451103.
PMCID: PMC1637544
Sustainability Science
Exploring the engine of anthropogenic iron cycles
Daniel B. Müller, Tao Wang, Benjamin Duval, and T. E. Graedel
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16111–16116. Published online 2006 October 19. doi: 10.1073/pnas.0603375103.
PMCID: PMC1637545
Biological Sciences
Applied Biological Sciences
Anisotropic mechanosensing by mesenchymal stem cells
Kyle Kurpinski, Julia Chu, Craig Hashi, and Song Li
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16095–16100. Published online 2006 October 23. doi: 10.1073/pnas.0604182103.
PMCID: PMC1637542
Biochemistry
Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase
Ling Qin, Carrie Hiser, Anne Mulichak, R. Michael Garavito, and Shelagh Ferguson-Miller
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16117–16122. Published online 2006 October 18. doi: 10.1073/pnas.0606149103.
PMCID: PMC1616942
Crystal structure of a photoactivated deprotonated intermediate of rhodopsin
David Salom, David T. Lodowski, Ronald E. Stenkamp, Isolde Le Trong, Marcin Golczak, Beata Jastrzebska, Tim Harris, Juan A. Ballesteros, and Krzysztof Palczewski
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16123–16128. Published online 2006 October 23. doi: 10.1073/pnas.0608022103.
PMCID: PMC1637547
Three strategically placed hydrogen-bonding residues convert a proton pump into a sensory receptor
Yuki Sudo and John L. Spudich
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16129–16134. Published online 2006 October 18. doi: 10.1073/pnas.0607467103.
PMCID: PMC1637548
Identification of a histidine-tyrosine cross-link in the active site of the cbb3-type cytochrome c oxidase from Rhodobacter sphaeroides
Virve Rauhamäki, Marc Baumann, Rabah Soliymani, Anne Puustinen, and Mårten Wikström
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16135–16140. Published online 2006 October 23. doi: 10.1073/pnas.0606254103.
PMCID: PMC1637549
Reaction mechanism of guanidinoacetate methyltransferase, concerted or step-wise
Xiaodong Zhang and Thomas C. Bruice
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16141–16146. Published online 2006 October 19. doi: 10.1073/pnas.0607503103.
PMCID: PMC1637550
Functional reconstitution and characterization of Pyrococcus furiosus RNase P
Hsin-Yue Tsai, Dileep K. Pulukkunat, Walter K. Woznick, and Venkat Gopalan
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16147–16152. Published online 2006 October 19. doi: 10.1073/pnas.0608000103.
PMCID: PMC1637551
Isoelectric focusing technology quantifies protein signaling in 25 cells
Roger A. O'Neill, Arunashree Bhamidipati, Xiahui Bi, Debabrita Deb-Basu, Linda Cahill, Jason Ferrante, Erik Gentalen, Marc Glazer, John Gossett, Kevin Hacker, Celeste Kirby, James Knittle, Robert Loder, Catherine Mastroieni, Michael MacLaren, Thomas Mills, Uyen Nguyen, Nineveh Parker, Audie Rice, David Roach, Daniel Suich, David Voehringer, Karl Voss, Jade Yang, Tom Yang, and Peter B. Vander Horn
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16153–16158. Published online 2006 October 19. doi: 10.1073/pnas.0607973103.
PMCID: PMC1618307
Different modes of SecY–SecA interactions revealed by site-directed in vivo photo-cross-linking
Hiroyuki Mori and Koreaki Ito
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16159–16164. Published online 2006 October 23. doi: 10.1073/pnas.0606390103.
PMCID: PMC1621050
Enzyme–microbe synergy during cellulose hydrolysis by Clostridium thermocellum
Yanpin Lu, Yi-Heng Percival Zhang, and Lee R. Lynd
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16165–16169. Published online 2006 October 23. doi: 10.1073/pnas.0605381103.
PMCID: PMC1637554
Definition of the mitochondrial proteome by measurement of molecular masses of membrane proteins
Joe Carroll, Ian M. Fearnley, and John E. Walker
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16170–16175. Published online 2006 October 23. doi: 10.1073/pnas.0607719103.
PMCID: PMC1621045
Independent and simultaneous translocation of two substrates by a nucleotide sugar transporter
Carolina E. Caffaro, Carlos B. Hirschberg, and Patricia M. Berninsone
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16176–16181. Published online 2006 October 23. doi: 10.1073/pnas.0608159103.
PMCID: PMC1621047
Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium
Jilin Zhou, Young Pyo Jang, So Ra Kim, and Janet R. Sparrow
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16182–16187. Published online 2006 October 23. doi: 10.1073/pnas.0604255103.
PMCID: PMC1637557
Impaired nucleotide excision repair upon macrophage differentiation is corrected by E1 ubiquitin-activating enzyme
Thierry Nouspikel and Philip C. Hanawalt
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16188–16193. Published online 2006 October 23. doi: 10.1073/pnas.0607769103.
PMCID: PMC1621053
Biophysics
Acceleration of the recognition rate between grafted ligands and receptors with magnetic forces
J. Baudry, C. Rouzeau, C. Goubault, C. Robic, L. Cohen-Tannoudji, A. Koenig, E. Bertrand, and J. Bibette
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16076–16078. Published online 2006 October 18. doi: 10.1073/pnas.0607991103.
PMCID: PMC1637538
Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals
Gil Goobes, Rivka Goobes, Ora Schueler-Furman, David Baker, Patrick S. Stayton, and Gary P. Drobny
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16083–16088. Published online 2006 October 23. doi: 10.1073/pnas.0607193103.
PMCID: PMC1637540
Structural and dynamical changes in an α-subunit of a heterotrimeric G protein along the activation pathway
Ned Van Eps, William M. Oldham, Heidi E. Hamm, and Wayne L. Hubbell
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16194–16199. Published online 2006 October 19. doi: 10.1073/pnas.0607972103.
PMCID: PMC1637559
On structural transitions, thermodynamic equilibrium, and the phase diagram of DNA and RNA duplexes under torque and tension
Jeff Wereszczynski and Ioan Andricioaei
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16200–16205. Published online 2006 October 23. doi: 10.1073/pnas.0603850103.
PMCID: PMC1637560
Monitoring intermediate filament assembly by small-angle x-ray scattering reveals the molecular architecture of assembly intermediates
Anna V. Sokolova, Laurent Kreplak, Tatjana Wedig, Norbert Mücke, Dmitri I. Svergun, Harald Herrmann, Ueli Aebi, and Sergei V. Strelkov
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16206–16211. Published online 2006 October 18. doi: 10.1073/pnas.0603629103.
PMCID: PMC1637561
Structure of electron transfer flavoprotein-ubiquinone oxidoreductase and electron transfer to the mitochondrial ubiquinone pool
Jian Zhang, Frank E. Frerman, and Jung-Ja P. Kim
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16212–16217. Published online 2006 October 18. doi: 10.1073/pnas.0604567103.
PMCID: PMC1637562
Structure of phosphorylated enzyme I, the phosphoenolpyruvate:sugar phosphotransferase system sugar translocation signal protein
Alexey Teplyakov, Kap Lim, Peng-Peng Zhu, Geeta Kapadia, Celia C. H. Chen, Jennifer Schwartz, Andrew Howard, Prasad T. Reddy, Alan Peterkofsky, and Osnat Herzberg
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16218–16223. Published online 2006 October 19. doi: 10.1073/pnas.0607587103.
PMCID: PMC1618308
Yeast mitochondrial ADP/ATP carriers are monomeric in detergents
Lisa Bamber, Marilyn Harding, P. Jonathan G. Butler, and Edmund R. S. Kunji
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16224–16229. Published online 2006 October 20. doi: 10.1073/pnas.0607640103.
PMCID: PMC1618811
An approach to crystallizing proteins by synthetic symmetrization
D. Rey Banatao, Duilio Cascio, Christopher S. Crowley, Mark R. Fleissner, Heather L. Tienson, and Todd O. Yeates
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16230–16235. Published online 2006 October 18. doi: 10.1073/pnas.0607674103.
PMCID: PMC1637565
Role of histone tails in chromatin folding revealed by a mesoscopic oligonucleosome model
Gaurav Arya and Tamar Schlick
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16236–16241. Published online 2006 October 23. doi: 10.1073/pnas.0604817103.
PMCID: PMC1637566
Membrane-dependent oligomeric structure and pore formation of a β-hairpin antimicrobial peptide in lipid bilayers from solid-state NMR
Rajeswari Mani, Sarah D. Cady, Ming Tang, Alan J. Waring, Robert I. Lehrer, and Mei Hong
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16242–16247. Published online 2006 October 23. doi: 10.1073/pnas.0605079103.
PMCID: PMC1637567
General structural motifs of amyloid protofilaments
Neil Ferguson, Johanna Becker, Henning Tidow, Sandra Tremmel, Timothy D. Sharpe, Gerd Krause, Jeremy Flinders, Miriana Petrovich, John Berriman, Hartmut Oschkinat, and Alan R. Fersht
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16248–16253. Published online 2006 October 23. doi: 10.1073/pnas.0607815103.
PMCID: PMC1637568
Cell Biology
From the Cover:
A rapid genome-scale response of the transcriptional oscillator to perturbation reveals a period-doubling path to phenotypic change
Caroline M. Li and Robert R. Klevecz
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16254–16259. Published online 2006 October 16. doi: 10.1073/pnas.0604860103.
PMCID: PMC1613231
PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription
Marco Sandri, Jiandie Lin, Christoph Handschin, Wenli Yang, Zoltan P. Arany, Stewart H. Lecker, Alfred L. Goldberg, and Bruce M. Spiegelman
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16260–16265. Published online 2006 October 19. doi: 10.1073/pnas.0607795103.
PMCID: PMC1637570
Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch
Sylvie Giuriato, Sandra Ryeom, Alice C. Fan, Pavan Bachireddy, Ryan C. Lynch, Matthew J. Rioth, Jan van Riggelen, Andrew M. Kopelman, Emmanuelle Passegué, Flora Tang, Judah Folkman, and Dean W. Felsher
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16266–16271. Published online 2006 October 20. doi: 10.1073/pnas.0608017103.
PMCID: PMC1637571
Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone
Marius C. Jones, Luca Fusi, Jenny H. Higham, Hany Abdel-Hafiz, Kathryn B. Horwitz, Eric W.-F. Lam, and Jan J. Brosens
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16272–16277. Published online 2006 October 19. doi: 10.1073/pnas.0603002103.
PMCID: PMC1637572
Macrophage inhibitory cytokine 1 mediates a p53-dependent protective arrest in S phase in response to starvation for DNA precursors
Mukesh K. Agarwal, Kedar Hastak, Mark W. Jackson, Samuel N. Breit, George R. Stark, and Munna L. Agarwal
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16278–16283. Published online 2006 October 18. doi: 10.1073/pnas.0607210103.
PMCID: PMC1637573
β-Arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes
Keshava Rajagopal, Erin J. Whalen, Jonathan D. Violin, Jonathan A. Stiber, Paul B. Rosenberg, Richard T. Premont, Thomas M. Coffman, Howard A. Rockman, and Robert J. Lefkowitz
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16284–16289. Published online 2006 October 23. doi: 10.1073/pnas.0607583103.
PMCID: PMC1637574
Pds1/Esp1-dependent and -independent sister chromatid separation in mutants defective for protein phosphatase 2A
Xianying Tang and Yanchang Wang
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16290–16295. Published online 2006 October 18. doi: 10.1073/pnas.0607856103.
PMCID: PMC1637575
The p110α isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation
Jean J. Zhao, Hailing Cheng, Shidong Jia, Li Wang, Ole V. Gjoerup, Aki Mikami, and Thomas M. Roberts
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16296–16300. Published online 2006 October 23. doi: 10.1073/pnas.0607899103.
PMCID: PMC1637576
Stimulatory effect of voluntary exercise or fat removal (partial lipectomy) on apoptosis in the skin of UVB light-irradiated mice
Yao-Ping Lu, You-Rong Lou, Bonnie Nolan, Qing-Yun Peng, Jian-Guo Xie, George C. Wagner, and Allan H. Conney
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16301–16306. Published online 2006 October 23. doi: 10.1073/pnas.0607789103.
PMCID: PMC1637577
Developmental Biology
Sog/Chordin is required for ventral-to-dorsal Dpp/BMP transport and head formation in a short germ insect
Maurijn van der Zee, Oliver Stockhammer, Cornelia von Levetzow, Rodrigo Nunes da Fonseca, and Siegfried Roth
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16307–16312. Published online 2006 October 18. doi: 10.1073/pnas.0605154103.
PMCID: PMC1637578
Jun NH2-terminal kinase (JNK) prevents nuclear β-catenin accumulation and regulates axis formation in Xenopus embryos
Guanghong Liao, Qinghua Tao, Matthew Kofron, Juei-Suei Chen, Aryn Schloemer, Roger J. Davis, Jen-Chih Hsieh, Chris Wylie, Janet Heasman, and Chia-Yi Kuan
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16313–16318. Published online 2006 October 23. doi: 10.1073/pnas.0602557103.
PMCID: PMC1637579
Murine inner cell mass-derived lineages depend on Sall4 function
Ulrich Elling, Christian Klasen, Tobias Eisenberger, Katrin Anlag, and Mathias Treier
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16319–16324. Published online 2006 October 23. doi: 10.1073/pnas.0607884103.
PMCID: PMC1637580
Establishment of stable cell lines of Drosophila germ-line stem cells
Yuzo Niki, Takafumi Yamaguchi, and Anthony P. Mahowald
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16325–16330. Published online 2006 October 20. doi: 10.1073/pnas.0607435103.
PMCID: PMC1637581
Evolution
Ancient polymorphism and functional variation in the primate MHC-DQA1 5′ cis-regulatory region
Dagan A. Loisel, Matthew V. Rockman, Gregory A. Wray, Jeanne Altmann, and Susan C. Alberts
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16331–16336. Published online 2006 October 19. doi: 10.1073/pnas.0607662103.
PMCID: PMC1637582
Evolution of complexity in signaling pathways
Orkun S. Soyer and Sebastian Bonhoeffer
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16337–16342. Published online 2006 October 23. doi: 10.1073/pnas.0604449103.
PMCID: PMC1621048
Good genes sexual selection in nature
John A. Byers and Lisette Waits
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16343–16345. Published online 2006 October 23. doi: 10.1073/pnas.0608184103.
PMCID: PMC1637584
From the Cover:
Evolutionary trade-off between weapons and testes
Leigh W. Simmons and Douglas J. Emlen
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16346–16351. Published online 2006 October 19. doi: 10.1073/pnas.0603474103.
PMCID: PMC1637585
Genome scan for cis-regulatory DNA motifs associated with social behavior in honey bees
Saurabh Sinha, Xu Ling, Charles W. Whitfield, Chengxiang Zhai, and Gene E. Robinson
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16352–16357. Published online 2006 October 25. doi: 10.1073/pnas.0607448103.
PMCID: PMC1637586
Genetics
Caspar, a suppressor of antibacterial immunity in Drosophila
Myungjin Kim, Jun Hee Lee, Soo Young Lee, Eunhee Kim, and Jongkyeong Chung
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16358–16363. Published online 2006 October 18. doi: 10.1073/pnas.0603238103.
PMCID: PMC1637587
From the Cover:
Stability of inbred mouse strain differences in behavior and brain size between laboratories and across decades
Douglas Wahlsten, Alexander Bachmanov, Deborah A. Finn, and John C. Crabbe
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16364–16369. Published online 2006 October 19. doi: 10.1073/pnas.0605342103.
PMCID: PMC1618164
Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells
Jason Morton, M. Wayne Davis, Erik M. Jorgensen, and Dana Carroll
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16370–16375. Published online 2006 October 23. doi: 10.1073/pnas.0605633103.
PMCID: PMC1637589
Ubiquitin-associated domain of Mex67 synchronizes recruitment of the mRNA export machinery with transcription
Carole Gwizdek, Nahid Iglesias, Manuel S. Rodriguez, Batool Ossareh-Nazari, Maria Hobeika, Gilles Divita, Françoise Stutz, and Catherine Dargemont
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16376–16381. Published online 2006 October 20. doi: 10.1073/pnas.0607941103.
PMCID: PMC1637590
Hypersensitivity to oxygen and shortened lifespan in a Drosophila mitochondrial complex II mutant
David W. Walker, Petr Hájek, Julien Muffat, Dan Knoepfle, Stephanie Cornelison, Giuseppe Attardi, and Seymour Benzer
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16382–16387. Published online 2006 October 20. doi: 10.1073/pnas.0607918103.
PMCID: PMC1618815
Immunology
Differential requirement for Lck during primary and memory CD8+ T cell responses
Kavita Tewari, Jane Walent, John Svaren, Rose Zamoyska, and M. Suresh
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16388–16393. Published online 2006 October 23. doi: 10.1073/pnas.0602565103.
PMCID: PMC1637592
Role of ABCC1 in export of sphingosine-1-phosphate from mast cells
Poulami Mitra, Carole A. Oskeritzian, Shawn G. Payne, Michael A. Beaven, Sheldon Milstien, and Sarah Spiegel
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16394–16399. Published online 2006 October 18. doi: 10.1073/pnas.0603734103.
PMCID: PMC1637593
Modeling CTLA4-linked autoimmunity with RNA interference in mice
Zhibin Chen, John Stockton, Diane Mathis, and Christophe Benoist
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16400–16405. Published online 2006 October 23. doi: 10.1073/pnas.0607854103.
PMCID: PMC1637594
Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer
Gustavo Mostoslavsky, Attila J. Fabian, Sean Rooney, Frederick W. Alt, and Richard C. Mulligan
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16406–16411. Published online 2006 October 24. doi: 10.1073/pnas.0608130103.
PMCID: PMC1637595
Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)
Mitsunori Shiroishi, Kimiko Kuroki, Linda Rasubala, Kouhei Tsumoto, Izumi Kumagai, Eiji Kurimoto, Koichi Kato, Daisuke Kohda, and Katsumi Maenaka
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16412–16417. Published online 2006 October 20. doi: 10.1073/pnas.0605228103.
PMCID: PMC1637596
A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation
Patricia C. Fulkerson, Christine A. Fischetti, Melissa L. McBride, Lynn M. Hassman, Simon P. Hogan, and Marc E. Rothenberg
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16418–16423. Published online 2006 October 23. doi: 10.1073/pnas.0607863103.
PMCID: PMC1637597
Rel/NF-κB double mutants reveal that cellular immunity is central to Drosophila host defense
Nina Matova and Kathryn V. Anderson
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16424–16429. Published online 2006 October 23. doi: 10.1073/pnas.0605721103.
PMCID: PMC1637598
Proinsulin is encoded by an RNA splice variant in human blood myeloid cells
Parth Narendran, Alana M. Neale, Bo Han Lee, Katrina Ngui, Raymond J. Steptoe, Grant Morahan, Ole Madsen, James A. Dromey, Kent P. Jensen, and Leonard C. Harrison
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16430–16435. Published online 2006 October 19. doi: 10.1073/pnas.0607380103.
PMCID: PMC1618309
Medical Sciences
Radiolabeled somatostatin receptor antagonists are preferable to agonists for in vivo peptide receptor targeting of tumors
Mihaela Ginj, Hanwen Zhang, Beatrice Waser, Renzo Cescato, Damian Wild, Xuejuan Wang, Judit Erchegyi, Jean Rivier, Helmut R. Mäcke, and Jean Claude Reubi
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16436–16441. Published online 2006 October 20. doi: 10.1073/pnas.0607761103.
PMCID: PMC1618814
Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene
Warren S. Alexander, Elizabeth M. Viney, Jian-Guo Zhang, Donald Metcalf, Maria Kauppi, Craig D. Hyland, Marina R. Carpinelli, William Stevenson, Ben A. Croker, Adrienne A. Hilton, Sarah Ellis, Carly Selan, Harshal H. Nandurkar, Christopher C. Goodnow, Benjamin T. Kile, Nicos A. Nicola, Andrew W. Roberts, and Douglas J. Hilton
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16442–16447. Published online 2006 October 24. doi: 10.1073/pnas.0607872103.
PMCID: PMC1637601
RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins
Shu Xiao, Dong Li, Hai-Qing Zhu, Man-Gen Song, Xiao-Rong Pan, Pei-Min Jia, Lin-Ling Peng, Ai-Xia Dou, Guo-Qiang Chen, Sai-Juan Chen, Zhu Chen, and Jian-Hua Tong
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16448–16453. Published online 2006 October 18. doi: 10.1073/pnas.0607830103.
PMCID: PMC1637602
Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates
Giovanni Solinas, Willscott Naugler, Francesco Galimi, Myung-Shik Lee, and Michael Karin
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16454–16459. Published online 2006 October 18. doi: 10.1073/pnas.0607626103.
PMCID: PMC1637603
Enforced expression of the homeobox gene Mixl1 impairs hematopoietic differentiation and results in acute myeloid leukemia
Stefan Glaser, Donald Metcalf, Li Wu, Adam H. Hart, Ladina DiRago, Sandra Mifsud, Angela D'Amico, Samantha Dagger, Chiara Campo, Angela C. Chan, David J. Izon, and Lorraine Robb
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16460–16465. Published online 2006 October 23. doi: 10.1073/pnas.0607776103.
PMCID: PMC1637604
Angiogenesis-independent tumor growth mediated by stem-like cancer cells
Per Ø. Sakariassen, Lars Prestegarden, Jian Wang, Kai-Ove Skaftnesmo, Rupavathana Mahesparan, Carla Molthoff, Peter Sminia, Eirik Sundlisæter, Anjan Misra, Berit Bølge Tysnes, Martha Chekenya, Hans Peters, Gabriel Lende, Karl Henning Kalland, Anne M. Øyan, Kjell Petersen, Inge Jonassen, Albert van der Kogel, Burt G. Feuerstein, A. Jorge A. Terzis, Rolf Bjerkvig, and Per Øyvind Enger
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16466–16471. Published online 2006 October 20. doi: 10.1073/pnas.0607668103.
PMCID: PMC1618812
The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis
Gong Yang, Daniel G. Rosen, Zhihong Zhang, Robert C. Bast, Jr., Gordon B. Mills, Justin A. Colacino, Imelda Mercado-Uribe, and Jinsong Liu
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16472–16477. Published online 2006 October 23. doi: 10.1073/pnas.0605752103.
PMCID: PMC1637606
Microbiology
Terminal organelle development in the cell wall-less bacterium Mycoplasma pneumoniae
Benjamin M. Hasselbring, Jarrat L. Jordan, Robert W. Krause, and Duncan C. Krause
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16478–16483. Published online 2006 October 24. doi: 10.1073/pnas.0608051103.
PMCID: PMC1637607
Cryo-EM visualization of transfer messenger RNA with two SmpBs in a stalled ribosome
Sukhjit Kaur, Reynald Gillet, Wen Li, Richard Gursky, and Joachim Frank
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16484–16489. Published online 2006 October 20. doi: 10.1073/pnas.0607438103.
PMCID: PMC1618813
Secretion signal recognition by YscN, the Yersinia type III secretion ATPase
Joseph A. Sorg, Bill Blaylock, and Olaf Schneewind
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16490–16495. Published online 2006 October 18. doi: 10.1073/pnas.0605974103.
PMCID: PMC1637609
Mammalian reovirus, a nonfusogenic nonenveloped virus, forms size-selective pores in a model membrane
Melina A. Agosto, Tijana Ivanovic, and Max L. Nibert
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16496–16501. Published online 2006 October 19. doi: 10.1073/pnas.0605835103.
PMCID: PMC1637610
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2
Michael A. Fischbach, Hening Lin, Lu Zhou, Yang Yu, Rebecca J. Abergel, David R. Liu, Kenneth N. Raymond, Barry L. Wanner, Roland K. Strong, Christopher T. Walsh, Alan Aderem, and Kelly D. Smith
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16502–16507. Published online 2006 October 23. doi: 10.1073/pnas.0604636103.
PMCID: PMC1637611
Establishment of a Nipah virus rescue system
Misako Yoneda, Vanessa Guillaume, Fusako Ikeda, Yuki Sakuma, Hiroki Sato, T. Fabian Wild, and Chieko Kai
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16508–16513. Published online 2006 October 19. doi: 10.1073/pnas.0606972103.
PMCID: PMC1618306
A B lymphocyte mitogen is a Brucella abortus virulence factor required for persistent infection
Juan Manuel Spera, Juan Esteban Ugalde, Juan Mucci, Diego J. Comerci, and Rodolfo Augusto Ugalde
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16514–16519. Published online 2006 October 19. doi: 10.1073/pnas.0603362103.
PMCID: PMC1637613
Neuroscience
Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly
Lei Chen, Guanghong Liao, Linda Yang, Kenneth Campbell, Masato Nakafuku, Chia-Yi Kuan, and Yi Zheng
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16520–16525. Published online 2006 October 18. doi: 10.1073/pnas.0603533103.
PMCID: PMC1637614
A homeostatic rule for inhibitory synapses promotes temporal sharpening and cortical reorganization
Samat B. Moldakarimov, James L. McClelland, and G. Bard Ermentrout
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16526–16531. Published online 2006 October 18. doi: 10.1073/pnas.0607589103.
PMCID: PMC1637615
A peptide zipcode sufficient for anterograde transport within amyloid precursor protein
Prasanna Satpute-Krishnan, Joseph A. DeGiorgis, Michael P. Conley, Marcus Jang, and Elaine L. Bearer
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16532–16537. Published online 2006 October 24. doi: 10.1073/pnas.0607527103.
PMCID: PMC1621108
Pheromone reception in fruit flies expressing a moth's odorant receptor
Zainulabeuddin Syed, Yuko Ishida, Katherine Taylor, Deborah A. Kimbrell, and Walter S. Leal
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16538–16543. Published online 2006 October 23. doi: 10.1073/pnas.0607874103.
PMCID: PMC1621046
Tactile guidance of prey capture in Etruscan shrews
Farzana Anjum, Hendrik Turni, Paul G. H. Mulder, Johannes van der Burg, and Michael Brecht
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16544–16549. Published online 2006 October 23. doi: 10.1073/pnas.0605573103.
PMCID: PMC1621049
Somatomotor and oculomotor inferior olivary neurons have distinct electrophysiological phenotypes
Francisco J. Urbano, John I. Simpson, and Rodolfo R. Llinás
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16550–16555. Published online 2006 October 18. doi: 10.1073/pnas.0607888103.
PMCID: PMC1616941
Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines
Xiang-ming Zha, John A. Wemmie, Steven H. Green, and Michael J. Welsh
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16556–16561. Published online 2006 October 23. doi: 10.1073/pnas.0608018103.
PMCID: PMC1621052
Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses
Anita Scheuber, Rachel Rudge, Lydia Danglot, Graca Raposo, Thomas Binz, Jean-Christophe Poncer, and Thierry Galli
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16562–16567. Published online 2006 October 20. doi: 10.1073/pnas.0603511103.
PMCID: PMC1637621
Flavonoid fisetin promotes ERK-dependent long-term potentiation and enhances memory
Pamela Maher, Tatsuhiro Akaishi, and Kazuho Abe
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16568–16573. Published online 2006 October 18. doi: 10.1073/pnas.0607822103.
PMCID: PMC1637622
Physiology
Phosphorylation of serine 1928 in the distal C-terminal domain of cardiac CaV1.2 channels during β1-adrenergic regulation
Joanne T. Hulme, Ruth E. Westenbroek, Todd Scheuer, and William A. Catterall
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16574–16579. Published online 2006 October 19. doi: 10.1073/pnas.0607294103.
PMCID: PMC1637623
Urocortin 2 modulates glucose utilization and insulin sensitivity in skeletal muscle
Alon Chen, Bhawanjit Brar, Cheol Soo Choi, David Rousso, Joan Vaughan, Yael Kuperman, Shee Ne Kim, Cindy Donaldson, Sean M. Smith, Pauline Jamieson, Chien Li, Tim R. Nagy, Gerald I. Shulman, Kuo-Fen Lee, and Wylie Vale
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16580–16585. Published online 2006 October 18. doi: 10.1073/pnas.0607337103.
PMCID: PMC1637624
A common mechanism underlies stretch activation and receptor activation of TRPC6 channels
Maria A. Spassova, Thamara Hewavitharana, Wen Xu, Jonathan Soboloff, and Donald L. Gill
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16586–16591. Published online 2006 October 20. doi: 10.1073/pnas.0606894103.
PMCID: PMC1637625
Plant Biology
The gene responsible for borate cross-linking of pectin Rhamnogalacturonan-II is required for plant reproductive tissue development and fertilization
Hiroaki Iwai, Akiko Hokura, Masahiro Oishi, Hiroshi Chida, Tadashi Ishii, Shingo Sakai, and Shinobu Satoh
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16592–16597. Published online 2006 October 19. doi: 10.1073/pnas.0605141103.
PMCID: PMC1637626
Roles of Arabidopsis ATP/ADP isopentenyltransferases and tRNA isopentenyltransferases in cytokinin biosynthesis
Kaori Miyawaki, Petr Tarkowski, Miho Matsumoto-Kitano, Tomohiko Kato, Shusei Sato, Danuse Tarkowska, Satoshi Tabata, Göran Sandberg, and Tatsuo Kakimoto
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16598–16603. Published online 2006 October 24. doi: 10.1073/pnas.0603522103.
PMCID: PMC1637627
Population Biology
Genomic dissection of behavioral maturation in the honey bee
Charles W. Whitfield, Yehuda Ben-Shahar, Charles Brillet, Isabelle Leoncini, Didier Crauser, Yves LeConte, Sandra Rodriguez-Zas, and Gene E. Robinson
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16068–16075. Published online 2006 October 25. doi: 10.1073/pnas.0606909103.
PMCID: PMC1622924
Evaluation of mortality trajectories in evolutionary biodemography
Stephan B. Munch and Marc Mangel
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16604–16607. Published online 2006 October 23. doi: 10.1073/pnas.0601735103.
PMCID: PMC1637628
Social Sciences
Environmental Sciences
Evaluation of mortality trajectories in evolutionary biodemography
Stephan B. Munch and Marc Mangel
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16604–16607. Published online 2006 October 23. doi: 10.1073/pnas.0601735103.
PMCID: PMC1637628
Psychology
Universality of color names
Delwin T. Lindsey and Angela M. Brown
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16608–16613. Published online 2006 October 17. doi: 10.1073/pnas.0607708103.
PMCID: PMC1614705
Corrections
Correction for Head-Gordon et al., Tetrahedral structure or chains for liquid water
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16614–16615. Published online 2006 October 18. doi: 10.1073/pnas.0608020103.
PMCID: PMC1637630
Corrects: Teresa Head-Gordon, et al. Tetrahedral structure or chains for liquid water. Proc Natl Acad Sci U S A. 2006 May 23; 103(21): 7973–7977.
Correction for Limberis et al., Adeno-associated virus serotype 9 vectors transduce murine alveolar and nasal epithelia and can be readministered
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16614–16615. Published online 2006 October 18. doi: 10.1073/pnas.0608505103.
PMCID: PMC1637631
Corrects: Maria P. Limberis, et al. Adeno-associated virus serotype 9 vectors transduce murine alveolar and nasal epithelia and can be readministered. Proc Natl Acad Sci U S A. 2006 August 29; 103(35): 12993–12998.
Correction for Colot et al., A high-throughput gene knockout procedure for Neurospora reveals functions for multiple transcription factors
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16614–16615. Published online 2006 October 18. doi: 10.1073/pnas.0608497103.
PMCID: PMC1637632
Corrects: Hildur V. Colot, et al. A high-throughput gene knockout procedure for Neurospora reveals functions for multiple transcription factors. Proc Natl Acad Sci U S A. 2006 July 5; 103(27): 10352–10357.
Correction for Kuroda et al., Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16614–16615. Published online 2006 October 18. doi: 10.1073/pnas.0608594103.
PMCID: PMC1637633
Corrects: Junya Kuroda, et al. Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic. Proc Natl Acad Sci U S A. 2006 October 3; 103(40): 14907–14912.
Correction for Zandbergen et al., Leishmania disease development depends on the presence of apoptotic promastigotes in the virulent inoculum
Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16615. Published online 2006 October 20. doi: 10.1073/pnas.0607935103.
PMCID: PMC1637634
Corrects: Ger van Zandbergen, et al. Leishmania disease development depends on the presence of apoptotic promastigotes in the virulent inoculum. Proc Natl Acad Sci U S A. 2006 September 12; 103(37): 13837–13842.
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