| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2006 August 15; 103(33): 12211–12212. doi: 10.1073/iti3306103.PMCID: PMC1567856 Commentaries Embryonic stem cells make human T cells Heather E. Fleming and David T. Scadden PMCID: PMC1567857 Agriculture: The selector of improbable mutations Jonathan Gressel and Avraham A. Levy PMCID: PMC1832258 Type 1, type 1.5, and type 2 diabetes: NOD the diabetes we thought it was Marc Y. Donath and Jan A. Ehses PMCID: PMC1567858 Stable neuron numbers from cradle to grave Richard S. Nowakowski PMCID: PMC1567859 Poxy models and rash decisions Ben Cooper PMCID: PMC1567860 Perspective Eastern North America as an independent center of plant domestication Bruce D. Smith PMCID: PMC1567861 Profile Profile of Ewine F. van Dishoeck Nick Zagorski PMCID: PMC1567862 Interstellar Chemistry Special Feature Introductory Perspective Interstellar chemistry William Klemperer PMCID: PMC1567863 Research Articles Chemistry in low-mass protostellar and protoplanetary regions Ewine F. van Dishoeck PMCID: PMC1567866 Monte Carlo studies of surface chemistry and nonthermal desorption involving interstellar grains Eric Herbst and Herma M. Cuppen PMCID: PMC1567867 Detection of low-frequency lambda-doublet transitions of the free 12CH and 13CH radicals M. C. McCarthy, S. Mohamed, J. M. Brown, and P. Thaddeus PMCID: PMC1567868 The galactic cosmic ray ionization rate A. Dalgarno PMCID: PMC1567869 The chemistry in circumstellar envelopes of evolved stars: Following the origin of the elements to the origin of life Lucy M. Ziurys PMCID: PMC1567870 Perspectives Interstellar H3+ Takeshi Oka PMCID: PMC1567864 Interferometric observations of large biologically interesting interstellar and cometary molecules Lewis E. Snyder PMCID: PMC1567865 Physical Sciences Applied Physical Sciences Microfluidic vias enable nested bioarrays and autoregulatory devices in Newtonian fluids Emil P. Kartalov, Christopher Walker, Clive R. Taylor, W. French Anderson, and Axel Scherer PMCID: PMC1567871 Nature designs tough collagen: Explaining the nanostructure of collagen fibrils Markus J. Buehler PMCID: PMC1567872 Permanent carbon dioxide storage in deep-sea sediments Kurt Zenz House, Daniel P. Schrag, Charles F. Harvey, and Klaus S. Lackner PMCID: PMC1567873 Astronomy Chemistry in low-mass protostellar and protoplanetary regions Ewine F. van Dishoeck PMCID: PMC1567866 Monte Carlo studies of surface chemistry and nonthermal desorption involving interstellar grains Eric Herbst and Herma M. Cuppen PMCID: PMC1567867 Detection of low-frequency lambda-doublet transitions of the free 12CH and 13CH radicals M. C. McCarthy, S. Mohamed, J. M. Brown, and P. Thaddeus PMCID: PMC1567868 The galactic cosmic ray ionization rate A. Dalgarno PMCID: PMC1567869 The chemistry in circumstellar envelopes of evolved stars: Following the origin of the elements to the origin of life Lucy M. Ziurys PMCID: PMC1567870 Chemistry Resorcinarenes are hexameric capsules in solution Tamar Evan-Salem, Inbal Baruch, Liat Avram, Yoram Cohen, Liam C. Palmer, and Julius Rebek, Jr. PMCID: PMC1567874 Solute-induced retardation of water dynamics probed directly by terahertz spectroscopy U. Heugen, G. Schwaab, E. Bründermann, M. Heyden, X. Yu, D. M. Leitner, and M. Havenith PMCID: PMC1567875 Resonance Raman spectroscopy of chloroperoxidase compound II provides direct evidence for the existence of an iron(IV)–hydroxide Kari L. Stone, Rachel K. Behan, and Michael T. Green PMCID: PMC1567876 Evaluation of RNA-binding specificity of aminoglycosides with DNA microarrays Fu-Sen Liang, William A. Greenberg, Jennifer A. Hammond, Julia Hoffmann, Steven R. Head, and Chi-Huey Wong PMCID: PMC1567877 Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo Masaaki Sawa, Tsui-Ling Hsu, Takeshi Itoh, Masakazu Sugiyama, Sarah R. Hanson, Peter K. Vogt, and Chi-Huey Wong PMCID: PMC1567886 End-to-end distance distributions and intrachain diffusion constants in unfolded polypeptide chains indicate intramolecular hydrogen bond formation Andreas Möglich, Karin Joder, and Thomas Kiefhaber PMCID: PMC1567890 Environmental Sciences Archaeal nitrification in the ocean Cornelia Wuchter, Ben Abbas, Marco J. L. Coolen, Lydie Herfort, Judith van Bleijswijk, Peer Timmers, Marc Strous, Eva Teira, Gerhard J. Herndl, Jack J. Middelburg, Stefan Schouten, and Jaap S. Sinninghe Damsté PMCID: PMC1533803 Physics Crystallography on curved surfaces Vincenzo Vitelli, J. B. Lucks, and D. R. Nelson PMCID: PMC1533801 Vesicles surfing on a lipid bilayer: Self-induced haptotactic motion Jéröme Solon, Pia Streicher, Ralf Richter, Françoise Brochard-Wyart, and Patricia Bassereau PMCID: PMC1567888 Statistics Model-based analysis of tiling-arrays for ChIP-chip W. Evan Johnson, Wei Li, Clifford A. Meyer, Raphael Gottardo, Jason S. Carroll, Myles Brown, and X. Shirley Liu PMCID: PMC1567901 Biological Sciences Agricultural Sciences From the Cover:
A codon deletion confers resistance to herbicides inhibiting protoporphyrinogen oxidase William L. Patzoldt, Aaron G. Hager, Joel S. McCormick, and Patrick J. Tranel PMCID: PMC1567880 Applied Biological Sciences Nature designs tough collagen: Explaining the nanostructure of collagen fibrils Markus J. Buehler PMCID: PMC1567872 Osteogenic differentiation of mouse adipose-derived adult stromal cells requires retinoic acid and bone morphogenetic protein receptor type IB signaling Derrick C. Wan, Yun-Ying Shi, Randall P. Nacamuli, Natalina Quarto, Karen M. Lyons, and Michael T. Longaker PMCID: PMC1567881 Biochemistry Evaluation of RNA-binding specificity of aminoglycosides with DNA microarrays Fu-Sen Liang, William A. Greenberg, Jennifer A. Hammond, Julia Hoffmann, Steven R. Head, and Chi-Huey Wong PMCID: PMC1567877 Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri Ashraf Alhapel, Daniel J. Darley, Nadine Wagener, Elke Eckel, Nora Elsner, and Antonio J. Pierik PMCID: PMC1562527 TAF4 nucleates a core subcomplex of TFIID and mediates activated transcription from a TATA-less promoter Kevin J. Wright, Michael T. Marr, II, and Robert Tjian PMCID: PMC1567882 Competitive recruitment of the periplasmic translocation portal TolB by a natively disordered domain of colicin E9 Steven R. Loftus, Daniel Walker, Maria J. Maté, Daniel A. Bonsor, Richard James, Geoffrey R. Moore, and Colin Kleanthous PMCID: PMC1567883 The essential GTPase YphC displays a major domain rearrangement associated with nucleotide binding Stephen P. Muench, Ling Xu, Svetlana E. Sedelnikova, and David W. Rice PMCID: PMC1567884 The structure of the endoribonuclease XendoU: From small nucleolar RNA processing to severe acute respiratory syndrome coronavirus replication Fabiana Renzi, Elisa Caffarelli, Pietro Laneve, Irene Bozzoni, Maurizio Brunori, and Beatrice Vallone PMCID: PMC1567885 Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo Masaaki Sawa, Tsui-Ling Hsu, Takeshi Itoh, Masakazu Sugiyama, Sarah R. Hanson, Peter K. Vogt, and Chi-Huey Wong PMCID: PMC1567886 Calbindin D9k knockout mice are indistinguishable from wild-type mice in phenotype and serum calcium level Galina D. Kutuzova, Shirin Akhter, Sylvia Christakos, Janeen Vanhooke, Christine Kimmel-Jehan, and Hector F. DeLuca PMCID: PMC1567887 Biophysics Resonance Raman spectroscopy of chloroperoxidase compound II provides direct evidence for the existence of an iron(IV)–hydroxide Kari L. Stone, Rachel K. Behan, and Michael T. Green PMCID: PMC1567876 Vesicles surfing on a lipid bilayer: Self-induced haptotactic motion Jéröme Solon, Pia Streicher, Ralf Richter, Françoise Brochard-Wyart, and Patricia Bassereau PMCID: PMC1567888 Entropy-driven spatial organization of highly confined polymers: Lessons for the bacterial chromosome Suckjoon Jun and Bela Mulder PMCID: PMC1525299 End-to-end distance distributions and intrachain diffusion constants in unfolded polypeptide chains indicate intramolecular hydrogen bond formation Andreas Möglich, Karin Joder, and Thomas Kiefhaber PMCID: PMC1567890 West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody Bärbel Kaufmann, Grant E. Nybakken, Paul R. Chipman, Wei Zhang, Michael S. Diamond, Daved H. Fremont, Richard J. Kuhn, and Michael G. Rossmann PMCID: PMC1567891 Cell Biology Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon Michael Overholtzer, Jianmin Zhang, Gromoslaw A. Smolen, Beth Muir, Wenmei Li, Dennis C. Sgroi, Chu-Xia Deng, Joan S. Brugge, and Daniel A. Haber PMCID: PMC1533802 Myosin-X is a molecular motor that functions in filopodia formation Aparna B. Bohil, Brian W. Robertson, and Richard E. Cheney PMCID: PMC1567893 A picornavirus protein interacts with Ran-GTPase and disrupts nucleocytoplasmic transport Frederick W. Porter, Yury A. Bochkov, Alison J. Albee, Christiane Wiese, and Ann C. Palmenberg PMCID: PMC1567894 Basonuclins 1 and 2, whose genes share a common origin, are proteins with widely different properties and functions Amandine Vanhoutteghem and Philippe Djian PMCID: PMC1567895 The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity Meizhen Lou, Thomas P. J. Garrett, Neil M. McKern, Peter A. Hoyne, V. Chandana Epa, John D. Bentley, George O. Lovrecz, Leah J. Cosgrove, Maurice J. Frenkel, and Colin W. Ward PMCID: PMC1533800 Follicle-stimulating hormone/cAMP regulation of aromatase gene expression requires β-catenin Tehnaz N. Parakh, Jennifer A. Hernandez, Jean C. Grammer, Jennifer Weck, Mary Hunzicker-Dunn, Anthony J. Zeleznik, and John H. Nilson PMCID: PMC1533882 Developmental Biology Lateral positioning at the dorsal midline: Slit and Roundabout receptors guide Drosophila heart cell migration Edgardo Santiago-Martínez, Nadine H. Soplop, and Sunita G. Kramer PMCID: PMC1567898 Ecology Ice-age endurance: DNA evidence of a white spruce refugium in Alaska Lynn L. Anderson, Feng Sheng Hu, David M. Nelson, Rémy J. Petit, and Ken N. Paige PMCID: PMC1567899 Environmental Sciences Archaeal nitrification in the ocean Cornelia Wuchter, Ben Abbas, Marco J. L. Coolen, Lydie Herfort, Judith van Bleijswijk, Peer Timmers, Marc Strous, Eva Teira, Gerhard J. Herndl, Jack J. Middelburg, Stefan Schouten, and Jaap S. Sinninghe Damsté PMCID: PMC1533803 Evolution Early evolution of animal cell signaling and adhesion genes Scott A. Nichols, William Dirks, John S. Pearse, and Nicole King PMCID: PMC1567900 Analysis of Aurignacian interstratification at the Châtelperronian-type site and implications for the behavioral modernity of Neandertals João Zilhão, Francesco d’Errico, Jean-Guillaume Bordes, Arnaud Lenoble, Jean-Pierre Texier, and Jean-Philippe Rigaud PMCID: PMC1567932 Genetics Model-based analysis of tiling-arrays for ChIP-chip W. Evan Johnson, Wei Li, Clifford A. Meyer, Raphael Gottardo, Jason S. Carroll, Myles Brown, and X. Shirley Liu PMCID: PMC1567901 The active FMR1 promoter is associated with a large domain of altered chromatin conformation with embedded local histone modifications Nele Gheldof, Tomoko M. Tabuchi, and Job Dekker PMCID: PMC1567902 Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia Lyudmila Georgieva, Valentina Moskvina, Tim Peirce, Nadine Norton, Nicholas J. Bray, Lesley Jones, Peter Holmans, Stuart MacGregor, Stanley Zammit, Jennifer Wilkinson, Hywel Williams, Ivan Nikolov, Nigel Williams, Dobril Ivanov, Kenneth L. Davis, Vahram Haroutunian, Joseph D. Buxbaum, Nick Craddock, George Kirov, Michael J. Owen, and Michael C. O’Donovan PMCID: PMC1567903 Immunology Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes Rodolfo José Chaparro, Yves Konigshofer, Georg F. Beilhack, Judith A. Shizuru, Hugh O. McDevitt, and Yueh-hsiu Chien PMCID: PMC1832259 NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses Konstantin D. Taganov, Mark P. Boldin, Kuang-Jung Chang, and David Baltimore PMCID: PMC1567904 Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria Vincent Feuillet, Samir Medjane, Isabelle Mondor, Olivier Demaria, Philippe P. Pagni, Jorge E. Galán, Richard A. Flavell, and Lena Alexopoulou PMCID: PMC1567905 Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis Hiroaki Nozawa, Christopher Chiu, and Douglas Hanahan PMCID: PMC1531646 Medical Sciences Melanoma growth is reduced in fat-1 transgenic mice: Impact of omega-6/omega-3 essential fatty acids Shuhua Xia, Yan Lu, Jingdong Wang, Chengwei He, Song Hong, Charles N. Serhan, and Jing X. Kang PMCID: PMC1567907 Linkage between cellular communications, energy utilization, and proliferation in metastatic neuroendocrine cancers Joseph E. Ippolito, Matthew E. Merritt, Fredrik Bäckhed, Krista L. Moulder, Steven Mennerick, Jill K. Manchester, Seth T. Gammon, David Piwnica-Worms, and Jeffrey I. Gordon PMCID: PMC1533883 Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice Marc-Emmanuel Dumas, Richard H. Barton, Ayo Toye, Olivier Cloarec, Christine Blancher, Alice Rothwell, Jane Fearnside, Roger Tatoud, Véronique Blanc, John C. Lindon, Steve C. Mitchell, Elaine Holmes, Mark I. McCarthy, James Scott, Dominique Gauguier, and Jeremy K. Nicholson PMCID: PMC1567909 Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging Marc C. Meulener, Kexiang Xu, Leonor Thomson, Harry Ischiropoulos, and Nancy M. Bonini PMCID: PMC1533799 Memory enhancement in healthy older adults using a brain plasticity-based training program: A randomized, controlled study Henry W. Mahncke, Bonnie B. Connor, Jed Appelman, Omar N. Ahsanuddin, Joseph L. Hardy, Richard A. Wood, Nicholas M. Joyce, Tania Boniske, Sharona M. Atkins, and Michael M. Merzenich PMCID: PMC1526649 Microbiology Molecular model of a type III secretion system needle: Implications for host-cell sensing Janet E. Deane, Pietro Roversi, Frank S. Cordes, Steven Johnson, Roma Kenjale, Sarah Daniell, Frank Booy, William D. Picking, Wendy L. Picking, Ariel J. Blocker, and Susan M. Lea PMCID: PMC1567912 Wolbachia transinfection in Aedes aegypti: A potential gene driver of dengue vectors Toon Ruang-areerate and Pattamaporn Kittayapong PMCID: PMC1567913 Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release Wei Lu, Bo-Jian Zheng, Ke Xu, Wolfgang Schwarz, Lanying Du, Charlotte K. L. Wong, Jiadong Chen, Shuming Duan, Vincent Deubel, and Bing Sun PMCID: PMC1567914 Rewiring the severe acute respiratory syndrome coronavirus (SARS-CoV) transcription circuit: Engineering a recombination-resistant genome Boyd Yount, Rhonda S. Roberts, Lisa Lindesmith, and Ralph S. Baric PMCID: PMC1531645 Phosphate acquisition genes in Prochlorococcus ecotypes: Evidence for genome-wide adaptation Adam C. Martiny, Maureen L. Coleman, and Sallie W. Chisholm PMCID: PMC1567916 Broad-spectrum biofilm inhibition by a secreted bacterial polysaccharide Jaione Valle, Sandra Da Re, Nelly Henry, Thierry Fontaine, Damien Balestrino, Patricia Latour-Lambert, and Jean-Marc Ghigo PMCID: PMC1567917 Neuroscience From the Cover:
Neocortical neurogenesis in humans is restricted to development Ratan D. Bhardwaj, Maurice A. Curtis, Kirsty L. Spalding, Bruce A. Buchholz, David Fink, Thomas Björk-Eriksson, Claes Nordborg, Fred H. Gage, Henrik Druid, Peter S. Eriksson, and Jonas Frisén PMCID: PMC1567918 Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor Yoshiro Ishimaru, Hitoshi Inada, Momoka Kubota, Hanyi Zhuang, Makoto Tominaga, and Hiroaki Matsunami PMCID: PMC1531643 The significance of direct sunlight and polarized skylight in the ant’s celestial system of navigation Rüdiger Wehner and Martin Müller PMCID: PMC1567920 Sex- and clock-controlled expression of the neuropeptide F gene in Drosophila Gyunghee Lee, Jae Hoon Bahn, and Jae H. Park PMCID: PMC1567921 Cortical feedback depolarization waves: A mechanism of top-down influence on early visual areas Per E. Roland, Akitoshi Hanazawa, Calle Undeman, David Eriksson, Tamas Tompa, Hiroyuki Nakamura, Sonata Valentiniene, and Bashir Ahmed PMCID: PMC1531644 Viral tracing identifies distributed columnar organization in the olfactory bulb David C. Willhite, Katherine T. Nguyen, Arjun V. Masurkar, Charles A. Greer, Gordon M. Shepherd, and Wei R. Chen PMCID: PMC1567923 Finding neuroelectric activity under magnetic-field oscillations (NAMO) with magnetic resonance imaging in vivo Trong-Kha Truong and Allen W. Song PMCID: PMC1567924 Pharmacology Structure–activity relationships by interligand NOE-based design and synthesis of antiapoptotic compounds targeting Bid Barbara Becattini, Carsten Culmsee, Marilisa Leone, Dayong Zhai, Xiyun Zhang, Kevin J. Crowell, Michele F. Rega, Stefan Landshamer, John C. Reed, Nikolaus Plesnila, and Maurizio Pellecchia PMCID: PMC1567925 Activation of heterotrimeric G proteins by Smoothened Natalia A. Riobo, Berangere Saucy, Cherisse DiLizio, and David R. Manning PMCID: PMC1567926 Physiology Ouabain affinity determining residues lie close to the Na/K pump ion pathway Pablo Artigas and David C. Gadsby PMCID: PMC1567927 Voltage-dependent conformational changes in human Ca2+- and voltage-activated K+ channel, revealed by voltage-clamp fluorometry Nicoletta Savalli, Andrei Kondratiev, Ligia Toro, and Riccardo Olcese PMCID: PMC1567928 Plant Biology A Ca2+ signaling pathway regulates a K+ channel for low-K response in Arabidopsis Legong Li, Beom-Gi Kim, Yong Hwa Cheong, Girdhar K. Pandey, and Sheng Luan PMCID: PMC1567929 A redox-active FKBP-type immunophilin functions in accumulation of the photosystem II supercomplex in Arabidopsis thaliana Amparo Lima, Santiago Lima, Joshua H. Wong, Robert S. Phillips, Bob B. Buchanan, and Sheng Luan PMCID: PMC1567930 Population Biology From the Cover:
Smallpox transmission and control: Spatial dynamics in Great Britain Steven Riley and Neil M. Ferguson PMCID: PMC1567931 Social Sciences Anthropology Analysis of Aurignacian interstratification at the Châtelperronian-type site and implications for the behavioral modernity of Neandertals João Zilhão, Francesco d’Errico, Jean-Guillaume Bordes, Arnaud Lenoble, Jean-Pierre Texier, and Jean-Philippe Rigaud PMCID: PMC1567932 Psychology Infant brains detect arithmetic errors Andrea Berger, Gabriel Tzur, and Michael I. Posner PMCID: PMC1567933 Correction Corrections for Amit et al., Direct observation of RuvAB-catalyzed branch migration of single Holliday junctions and Dawid et al., Single-molecule study of RuvAB-mediated Holliday-junction migration PMCID: PMC1567934 Corrects: Roee Amit, et al. Direct observation of RuvAB-catalyzed branch migration of single Holliday junctions. Proc Natl Acad Sci U S A. 2004 August 10; 101(32): 11605–11610. |
