| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2006 June 27; 103(26): 9747–9748. doi: 10.1073/iti2606103.PMCID: PMC1502522 Commentaries Aluminum tolerance genes are conserved between monocots and dicots Jurandir Vieira Magalhaes PMCID: PMC1502523 Glial cell line-derived neurotrophic factor maintains a POZ-itive influence on stem cells Christopher Payne and Robert E. Braun PMCID: PMC1502524 Profile Profile of William D. Nordhaus Regina Nuzzo PMCID: PMC1502525 Physical Sciences Chemistry Lanthanide complexes as fluorescent indicators for neutral sugars and cancer biomarkers Onur Alptürk, Oleksandr Rusin, Sayo O. Fakayode, Weihua Wang, Jorge O. Escobedo, Isiah M. Warner, William E. Crowe, Vladimir Král, Jeff M. Pruet, and Robert M. Strongin PMCID: PMC1479863 Modeling the Lac repressor-operator assembly: The influence of DNA looping on Lac repressor conformation David Swigon, Bernard D. Coleman, and Wilma K. Olson PMCID: PMC1502547 Computer Sciences Low-dimensional, free-energy landscapes of protein-folding reactions by nonlinear dimensionality reduction Payel Das, Mark Moll, Hernán Stamati, Lydia E. Kavraki, and Cecilia Clementi PMCID: PMC1502548 Physics Directional sensing in eukaryotic chemotaxis: A balanced inactivation model Herbert Levine, David A. Kessler, and Wouter-Jan Rappel PMCID: PMC1502527 Biological Sciences Applied Biological Sciences Lanthanide complexes as fluorescent indicators for neutral sugars and cancer biomarkers Onur Alptürk, Oleksandr Rusin, Sayo O. Fakayode, Weihua Wang, Jorge O. Escobedo, Isiah M. Warner, William E. Crowe, Vladimir Král, Jeff M. Pruet, and Robert M. Strongin PMCID: PMC1479863 Biochemistry Terminal association of Rad54 protein with the Rad51–dsDNA filament Konstantin Kiianitsa, Jachen A. Solinger, and Wolf-Dietrich Heyer PMCID: PMC1502528 Phosphoproteomic analysis of Her2/neu signaling and inhibition Ron Bose, Henrik Molina, A. Scott Patterson, John K. Bitok, Balamurugan Periaswamy, Joel S. Bader, Akhilesh Pandey, and Philip A. Cole PMCID: PMC1502529 Regulation of nitrogenase by 2-oxoglutarate-reversible, direct binding of a PII-like nitrogen sensor protein to dinitrogenase Jeremy A. Dodsworth and John A. Leigh PMCID: PMC1502530 A genetically encoded fluorescent amino acid Daniel Summerer, Shuo Chen, Ning Wu, Alexander Deiters, Jason W. Chin, and Peter G. Schultz PMCID: PMC1502531 Structural and functional analysis of PucM, a hydrolase in the ureide pathway and a member of the transthyretin-related protein family Du-Kyo Jung, Youra Lee, Sung Goo Park, Byoung Chul Park, Ghyung-Hwa Kim, and Sangkee Rhee PMCID: PMC1502532 Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli Maria L. Galisteo, Yan Yang, Jesus Ureña, and Joseph Schlessinger PMCID: PMC1502533 A loop network within the anthrax toxin pore positions the phenylalanine clamp in an active conformation Roman A. Melnyk and R. John Collier PMCID: PMC1479862 Recruitment of mRNA cleavage/polyadenylation machinery by the yeast chromatin protein Sin1p/Spt2p Gitit Hershkovits, Haim Bangio, Ronit Cohen, and Don J. Katcoff PMCID: PMC1502535 Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2) Michael A. McDonough, Vivian Li, Emily Flashman, Rasheduzzaman Chowdhury, Christopher Mohr, Benoît M. R. Liénard, James Zondlo, Neil J. Oldham, Ian J. Clifton, Jeffrey Lewis, Luke A. McNeill, Robert J. M. Kurzeja, Kirsty S. Hewitson, Evelyn Yang, Steven Jordan, Rashid S. Syed, and Christopher J. Schofield PMCID: PMC1502536 Atomic structure of a nitrate-binding protein crucial for photosynthetic productivity Nicole M. Koropatkin, Himadri B. Pakrasi, and Thomas J. Smith PMCID: PMC1502537 Identifying and manipulating structural determinates linking catalytic specificities in terpene synthases Bryan T. Greenhagen, Paul E. O’Maille, Joseph P. Noel, and Joe Chappell PMCID: PMC1502538 Mechanism of action of a flavin-containing monooxygenase Subramaniam Eswaramoorthy, Jeffrey B. Bonanno, Stephen K. Burley, and Subramanyam Swaminathan PMCID: PMC1502539 Visualization of a group II intron in the 23S rRNA of a stable ribosome Jacoba G. Slagter-Jäger, Gregory S. Allen, Dorie Smith, Ingrid A. Hahn, Joachim Frank, and Marlene Belfort PMCID: PMC1502540 Biophysics Mechanics of actomyosin bonds in different nucleotide states are tuned to muscle contraction Bin Guo and William H. Guilford PMCID: PMC1502541 Chlamydial ribonucleotide reductase: Tyrosyl radical function in catalysis replaced by the FeIII-FeIV cluster N. Voevodskaya, A.-J. Narvaez, V. Domkin, E. Torrents, L. Thelander, and A. Gräslund PMCID: PMC1502542 How photosynthetic reaction centers control oxidation power in chlorophyll pairs P680, P700, and P870 Hiroshi Ishikita, Wolfram Saenger, Jacek Biesiadka, Bernhard Loll, and Ernst-Walter Knapp PMCID: PMC1502543 Structure and assembly of P-pili: A protruding hinge region used for assembly of a bacterial adhesion filament Xiang-Qi Mu and Esther Bullitt PMCID: PMC1502544 Long-range cooperative binding effects in a T cell receptor variable domain Beenu Moza, Rebecca A. Buonpane, Penny Zhu, Christine A. Herfst, A. K. M. Nur-ur Rahman, John K. McCormick, David M. Kranz, and Eric J. Sundberg PMCID: PMC1502545 The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement Charles L. Asbury, Daniel R. Gestaut, Andrew F. Powers, Andrew D. Franck, and Trisha N. Davis PMCID: PMC1502546 Modeling the Lac repressor-operator assembly: The influence of DNA looping on Lac repressor conformation David Swigon, Bernard D. Coleman, and Wilma K. Olson PMCID: PMC1502547 Low-dimensional, free-energy landscapes of protein-folding reactions by nonlinear dimensionality reduction Payel Das, Mark Moll, Hernán Stamati, Lydia E. Kavraki, and Cecilia Clementi PMCID: PMC1502548 Cell Biology H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks Thomas M. Marti, Eli Hefner, Luzviminda Feeney, Valerie Natale, and James E. Cleaver PMCID: PMC1502549 A mechanism of cell death involving an adenylyl cyclase/PKA signaling pathway is induced by the Cry1Ab toxin of Bacillus thuringiensis Xuebin Zhang, Mehmet Candas, Natalya B. Griko, Ronald Taussig, and Lee A. Bulla, Jr. PMCID: PMC1502550 Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas Kevin G. Chen, Julio C. Valencia, Barry Lai, Guofeng Zhang, Jill K. Paterson, François Rouzaud, Werner Berens, Stephen M. Wincovitch, Susan H. Garfield, Richard D. Leapman, Vincent J. Hearing, and Michael M. Gottesman PMCID: PMC1502551 A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor β Yong Wang, Nickolay Y. Chirgadze, Stephen L. Briggs, Sohaib Khan, Elwood V. Jensen, and Thomas P. Burris PMCID: PMC1502552 Developmental Biology Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages Y. Y. Dan, K. J. Riehle, C. Lazaro, N. Teoh, J. Haque, J. S. Campbell, and N. Fausto PMCID: PMC1502553 Loss of Aif function causes cell death in the mouse embryo, but the temporal progression of patterning is normal Doris Brown, Benjamin D. Yu, Nicholas Joza, Paule Bénit, Juanito Meneses, Meri Firpo, Pierre Rustin, Josef M. Penninger, and Gail R. Martin PMCID: PMC1502554 Evolution Extensive outcrossing and androdioecy in a vertebrate species that otherwise reproduces as a self-fertilizing hermaphrodite Mark Mackiewicz, Andrey Tatarenkov, D. Scott Taylor, Bruce J. Turner, and John C. Avise PMCID: PMC1502555 Pegasoferae, an unexpected mammalian clade revealed by tracking ancient retroposon insertions Hidenori Nishihara, Masami Hasegawa, and Norihiro Okada PMCID: PMC1479866 Novel genes derived from noncoding DNA in Drosophila melanogaster are frequently X-linked and exhibit testis-biased expression Mia T. Levine, Corbin D. Jones, Andrew D. Kern, Heather A. Lindfors, and David J. Begun PMCID: PMC1502557 Genetics Linking DNA-binding proteins to their recognition sequences by using protein microarrays Su-Wen Ho, Ghil Jona, Christina T. L. Chen, Mark Johnston, and Michael Snyder PMCID: PMC1502558 A Caenorhabditis elegans tissue model of radiation-induced reproductive cell death J. B. Weidhaas, D. M. Eisenmann, J. M. Holub, and S. V. Nallur PMCID: PMC1502559 Ionizing radiation induces caspase-dependent but Chk2- and p53-independent cell death in Drosophila melanogaster Anita Wichmann, Burnley Jaklevic, and Tin Tin Su PMCID: PMC1502560 A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation Dominic Ciavatta, Sundeep Kalantry, Terry Magnuson, and Oliver Smithies PMCID: PMC1479543 Immunology From the Cover:
Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3 Monika Kasprzycka, Michal Marzec, Xiaobin Liu, Qian Zhang, and Mariusz A. Wasik PMCID: PMC1502562 From the Cover:
A Tlr7 translocation accelerates systemic autoimmunity in murine lupus Srividya Subramanian, Katalin Tus, Quan-Zhen Li, Andrew Wang, Xiang-Hong Tian, Jinchun Zhou, Chaoying Liang, Guy Bartov, Lisa D. McDaniel, Xin J. Zhou, Roger A. Schultz, and Edward K. Wakeland PMCID: PMC1502563 Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage development Ruth Schwartz, Isaac Engel, Mohammad Fallahi-Sichani, Howard T. Petrie, and Cornelis Murre PMCID: PMC1502564 Medical Sciences The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1β production Jae Jin Chae, Geryl Wood, Seth L. Masters, Katharina Richard, Grace Park, Brian J. Smith, and Daniel L. Kastner PMCID: PMC1479864 Microbiology The guinea pig as a transmission model for human influenza viruses Anice C. Lowen, Samira Mubareka, Terrence M. Tumpey, Adolfo García-Sastre, and Peter Palese PMCID: PMC1502566 ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression Alice P. W. Poon, Haidong Gu, and Bernard Roizman PMCID: PMC1502567 The complete genome sequence of a chronic atrophic gastritis Helicobacter pylori strain: Evolution during disease progression Jung D. Oh, Helene Kling-Bäckhed, Marios Giannakis, Jian Xu, Robert S. Fulton, Lucinda A. Fulton, Holland S. Cordum, Chunyan Wang, Glendoria Elliott, Jennifer Edwards, Elaine R. Mardis, Lars G. Engstrand, and Jeffrey I. Gordon PMCID: PMC1480403 Molecular basis for PKR activation by PACT or dsRNA Shoudong Li, Gregory A. Peters, Keyang Ding, Xiaolun Zhang, Jun Qin, and Ganes C. Sen PMCID: PMC1502496 A humanized gnotobiotic mouse model of host–archaeal–bacterial mutualism Buck S. Samuel and Jeffrey I. Gordon PMCID: PMC1479766 Neuroscience Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development Kenji E. Orii, Youngsoo Lee, Naomi Kondo, and Peter J. McKinnon PMCID: PMC1502498 Involvement of human left dorsolateral prefrontal cortex in perceptual decision making is independent of response modality H. R. Heekeren, S. Marrett, D. A. Ruff, P. A. Bandettini, and L. G. Ungerleider PMCID: PMC1479865 Rab3 GTPase-activating protein regulates synaptic transmission and plasticity through the inactivation of Rab3 Ayuko Sakane, Shinji Manabe, Hiroyoshi Ishizaki, Miki Tanaka-Okamoto, Emi Kiyokage, Kazunori Toida, Takayuki Yoshida, Jun Miyoshi, Haruyuki Kamiya, Yoshimi Takai, and Takuya Sasaki PMCID: PMC1502500 Regulation of large dense-core vesicle volume and neurotransmitter content mediated by adaptor protein 3 Chad P. Grabner, Steven D. Price, Anna Lysakowski, Anne L. Cahill, and Aaron P. Fox PMCID: PMC1502501 Hippocampal disconnection contributes to memory dysfunction in individuals at risk for Alzheimer’s disease Travis R. Stoub, Leyla deToledo-Morrell, Glenn T. Stebbins, Sue Leurgans, David A. Bennett, and Raj C. Shah PMCID: PMC1479867 Spontaneous neuronal activity distinguishes human dorsal and ventral attention systems Michael D. Fox, Maurizio Corbetta, Abraham Z. Snyder, Justin L. Vincent, and Marcus E. Raichle PMCID: PMC1480402 Microstimulation of the somatosensory cortex can substitute for vibrissa stimulation during Pavlovian conditioning Rocio Leal-Campanario, José María Delgado-García, and Agnès Gruart PMCID: PMC1479767 Target cell-specific modulation of neuronal activity by astrocytes A. S. Kozlov, M. C. Angulo, E. Audinat, and S. Charpak PMCID: PMC1502505 Stargazin controls the pharmacology of AMPA receptor potentiators Susumu Tomita, Masayuki Sekiguchi, Keiji Wada, Roger A. Nicoll, and David S. Bredt PMCID: PMC1502506 Inactivation of cardiotrophin-like cytokine, a second ligand for ciliary neurotrophic factor receptor, leads to cold-induced sweating syndrome in a patient François Rousseau, Jean-François Gauchat, James G. McLeod, Sylvie Chevalier, Catherine Guillet, Florence Guilhot, Isabelle Cognet, Josy Froger, Angelika F. Hahn, Per M. Knappskog, Hugues Gascan, and Helge Boman PMCID: PMC1502507 The BMAL1 C terminus regulates the circadian transcription feedback loop Yota B. Kiyohara, Sayaka Tagao, Filippo Tamanini, Akira Morita, Yukiko Sugisawa, Maya Yasuda, Iori Yamanaka, Hiroki R. Ueda, Gijsbertus T. J. van der Horst, Takao Kondo, and Kazuhiro Yagita PMCID: PMC1502508 Pharmacology From the Cover:
Discovery of a small-molecule HIV-1 integrase inhibitor-binding site Laith Q. Al-Mawsawi, Valery Fikkert, Raveendra Dayam, Myriam Witvrouw, Terrence R. Burke, Jr., Christoph H. Borchers, and Nouri Neamati PMCID: PMC1502509 Physiology Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-γ coactivator 1α Zoltan Arany, Mikhail Novikov, Sherry Chin, Yanhong Ma, Anthony Rosenzweig, and Bruce M. Spiegelman PMCID: PMC1502510 Leptin (ob gene) of the South African clawed frog Xenopus laevis Erica J. Crespi and Robert J. Denver PMCID: PMC1502511 Plant Biology An endogenous peptide signal in Arabidopsis activates components of the innate immune response Alisa Huffaker, Gregory Pearce, and Clarence A. Ryan PMCID: PMC1502512 The cell surface leucine-rich repeat receptor for AtPep1, an endogenous peptide elicitor in Arabidopsis, is functional in transgenic tobacco cells Yube Yamaguchi, Gregory Pearce, and Clarence A. Ryan PMCID: PMC1502513 An inorganic carbon transport system responsible for acclimation specific to air levels of CO2 in Chlamydomonas reinhardtii Yingjun Wang and Martin H. Spalding PMCID: PMC1502514 Formation of two methylenedioxy bridges by a Sesamum CYP81Q protein yielding a furofuran lignan, (+)-sesamin Eiichiro Ono, Masaaki Nakai, Yuko Fukui, Namino Tomimori, Masako Fukuchi-Mizutani, Masayuki Saito, Honoo Satake, Takaharu Tanaka, Masumi Katsuta, Toshiaki Umezawa, and Yoshikazu Tanaka PMCID: PMC1502515 Functional conservation of cold shock domains in bacteria and higher plants Kentaro Nakaminami, Dale T. Karlson, and Ryozo Imai PMCID: PMC1502516 From the Cover:
Eugenol and isoeugenol, characteristic aromatic constituents of spices, are biosynthesized via reduction of a coniferyl alcohol ester Takao Koeduka, Eyal Fridman, David R. Gang, Daniel G. Vassão, Brenda L. Jackson, Christine M. Kish, Irina Orlova, Snejina M. Spassova, Norman G. Lewis, Joseph P. Noel, Thomas J. Baiga, Natalia Dudareva, and Eran Pichersky PMCID: PMC1502517 PHYTOCHROME KINASE SUBSTRATE 1 is a phototropin 1 binding protein required for phototropism Patricia Lariguet, Isabelle Schepens, Daniel Hodgson, Ullas V. Pedmale, Martine Trevisan, Chitose Kami, Matthieu de Carbonnel, José M. Alonso, Joseph R. Ecker, Emmanuel Liscum, and Christian Fankhauser PMCID: PMC1502518 Social Sciences Sustainability Science From the Cover:
Business strategies for conservation on private lands: Koa forestry as a case study Joshua H. Goldstein, Gretchen C. Daily, James B. Friday, Pamela A. Matson, Rosamond L. Naylor, and Peter Vitousek PMCID: PMC1502519 Corrections Correction for Cho et al., COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model PMCID: PMC1502520 Corrects: Chung-Hyun Cho, et al. COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model. Proc Natl Acad Sci U S A. 2006 March 28; 103(13): 4946–4951. Correction for Resnick et al., REVERSION-TO-ETHYLENE SENSITIVITY1, a conserved gene that regulates ethylene receptor function in Arabidopsis PMCID: PMC1502521 Corrects: Josephine S. Resnick, et al. From The Cover:
REVERSION-TO-ETHYLENE SENSITIVITY1, a conserved gene that regulates ethylene receptor function in Arabidopsis. Proc Natl Acad Sci U S A. 2006 May 16; 103(20): 7917–7922. |
