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Volume 103(10);  March 7, 2006
This Week in PNAS
In This Issue
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3495–3496. doi: 10.1073/iti1006103.
PMCID: PMC1450115
Commentaries
Materials design of solid electrolytes
Karlheinz Schwarz
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3497. Published online 2006 February 27. doi: 10.1073/pnas.0600327103.
PMCID: PMC1533771
Multiplying myosins
Holly V. Goodson and Scott C. Dawson
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3498–3499. Published online 2006 February 28. doi: 10.1073/pnas.0600045103.
PMCID: PMC1533772
A milestone for hepatitis C virus research: A virus generated in cell culture is fully viable in vivo
Jens Bukh and Robert H. Purcell
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3500–3501. Published online 2006 February 27. doi: 10.1073/pnas.0600551103.
PMCID: PMC1533773
Physical Sciences
Applied Physical Sciences
From the Cover:
Optimization of ionic conductivity in doped ceria
David A. Andersson, Sergei I. Simak, Natalia V. Skorodumova, Igor A. Abrikosov, and Börje Johansson
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3518–3521. Published online 2006 February 14. doi: 10.1073/pnas.0509537103.
PMCID: PMC1450116
Chemistry
Chiral N-salicylidene vanadyl carboxylate-catalyzed enantioselective aerobic oxidation of α-hydroxy esters and amides
Shiue-Shien Weng, Mei-Wen Shen, Jun-Qi Kao, Yogesh S. Munot, and Chien-Tien Chen
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3522–3527. Published online 2006 February 24. doi: 10.1073/pnas.0511021103.
PMCID: PMC1382168
Picosecond dynamics of a membrane protein revealed by 2D IR
Prabuddha Mukherjee, Itamar Kass, Isaiah T. Arkin, and Martin T. Zanni
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3528–3533. Published online 2006 February 27. doi: 10.1073/pnas.0508833103.
PMCID: PMC1383493
X-ray diffraction “fingerprinting” of DNA structure in solution for quantitative evaluation of molecular dynamics simulation
Xiaobing Zuo, Guanglei Cui, Kenneth M. Merz, Jr., Ligang Zhang, Frederick D. Lewis, and David M. Tiede
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3534–3539. Published online 2006 February 27. doi: 10.1073/pnas.0600022103.
PMCID: PMC1383498
Mechanism of arylating quinone toxicity involving Michael adduct formation and induction of endoplasmic reticulum stress
Xinhe Wang, Beena Thomas, Rakesh Sachdeva, Linnea Arterburn, Lucy Frye, Patrick G. Hatcher, David G. Cornwell, and Jiyan Ma
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3604–3609. Published online 2006 February 27. doi: 10.1073/pnas.0510962103.
PMCID: PMC1450130
Electron trap for DNA-bound repair enzymes: A strategy for DNA-mediated signaling
Eylon Yavin, Eric D. A. Stemp, Valerie L. O’Shea, Sheila S. David, and Jacqueline K. Barton
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3610–3614. Published online 2006 February 27. doi: 10.1073/pnas.0600239103.
PMCID: PMC1450131
Engineering
Initiation of shape-memory effect by inductive heating of magnetic nanoparticles in thermoplastic polymers
R. Mohr, K. Kratz, T. Weigel, M. Lucka-Gabor, M. Moneke, and A. Lendlein
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3540–3545. Published online 2006 February 28. doi: 10.1073/pnas.0600079103.
PMCID: PMC1383650
Environmental Sciences
Heterotrophic Archaea dominate sedimentary subsurface ecosystems off Peru
Jennifer F. Biddle, Julius S. Lipp, Mark A. Lever, Karen G. Lloyd, Ketil B. Sørensen, Rika Anderson, Helen F. Fredricks, Marcus Elvert, Timothy J. Kelly, Daniel P. Schrag, Mitchell L. Sogin, Jean E. Brenchley, Andreas Teske, Christopher H. House, and Kai-Uwe Hinrichs
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3846–3851. Published online 2006 February 27. doi: 10.1073/pnas.0600035103.
PMCID: PMC1533785
Biological Sciences
Agricultural Sciences
High-amylose wheat generated by RNA interference improves indices of large-bowel health in rats
Ahmed Regina, Anthony Bird, David Topping, Sarah Bowden, Judy Freeman, Tina Barsby, Behjat Kosar-Hashemi, Zhongyi Li, Sadequr Rahman, and Matthew Morell
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3546–3551. Published online 2006 February 28. doi: 10.1073/pnas.0510737103.
PMCID: PMC1450120
Anthropology
Body size, body proportions, and encephalization in a Middle Pleistocene archaic human from northern China
Karen R. Rosenberg, Lü Zuné, and Christopher B. Ruff
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3552–3556. Published online 2006 February 27. doi: 10.1073/pnas.0508681103.
PMCID: PMC1450121
Applied Biological Sciences
Human antibodies for immunotherapy development generated via a human B cell hybridoma technology
Jian Li, Tao Sai, Marc Berger, Qimin Chao, Diane Davidson, Gaurav Deshmukh, Brian Drozdowski, Wolfgang Ebel, Stephen Harley, Marianne Henry, Sara Jacob, Brad Kline, Ella Lazo, Frank Rotella, Eric Routhier, Kathryn Rudolph, Jeaneen Sage, Paul Simon, Jun Yao, Yuhong Zhou, Mani Kavuru, Tracey Bonfield, Mary Jane Thomassen, Philip M. Sass, Nicholas C. Nicolaides, and Luigi Grasso
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3557–3562. Published online 2006 February 27. doi: 10.1073/pnas.0511285103.
PMCID: PMC1383494
Biochemistry
X-ray diffraction “fingerprinting” of DNA structure in solution for quantitative evaluation of molecular dynamics simulation
Xiaobing Zuo, Guanglei Cui, Kenneth M. Merz, Jr., Ligang Zhang, Frederick D. Lewis, and David M. Tiede
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3534–3539. Published online 2006 February 27. doi: 10.1073/pnas.0600022103.
PMCID: PMC1383498
Structural characterization of autoinhibited c-Met kinase produced by coexpression in bacteria with phosphatase
Weiru Wang, Adhirai Marimuthu, James Tsai, Abhinav Kumar, Heike I. Krupka, Chao Zhang, Ben Powell, Yoshihisa Suzuki, Hoa Nguyen, Maryam Tabrizizad, Catherine Luu, and Brian L. West
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3563–3568. Published online 2006 February 28. doi: 10.1073/pnas.0600048103.
PMCID: PMC1450123
A DEAD-box protein alone promotes group II intron splicing and reverse splicing by acting as an RNA chaperone
Sabine Mohr, Manabu Matsuura, Philip S. Perlman, and Alan M. Lambowitz
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3569–3574. Published online 2006 February 27. doi: 10.1073/pnas.0600332103.
PMCID: PMC1450124
An elongated spine of buried core residues necessary for in vivo folding of the parallel β-helix of P22 tailspike adhesin
Ryan Simkovsky and Jonathan King
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3575–3580. Published online 2006 February 27. doi: 10.1073/pnas.0509087103.
PMCID: PMC1383501
Cofactor-containing antibodies: Crystal structure of the original yellow antibody
Xueyong Zhu, Paul Wentworth, Jr., Robert A. Kyle, Richard A. Lerner, and Ian A. Wilson
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3581–3585. Published online 2006 February 28. doi: 10.1073/pnas.0600251103.
PMCID: PMC1450126
Mutational unmasking of a tRNA-dependent pathway for preventing genetic code ambiguity
Amy M. Williams and Susan A. Martinis
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3586–3591. Published online 2006 February 27. doi: 10.1073/pnas.0507362103.
PMCID: PMC1383500
Calcium-dependent regulation of the voltage-gated sodium channel hH1: Intrinsic and extrinsic sensors use a common molecular switch
Vikas N. Shah, Tammy L. Wingo, Kevin L. Weiss, Christina K. Williams, Jeffrey R. Balser, and Walter J. Chazin
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3592–3597. Published online 2006 February 27. doi: 10.1073/pnas.0507397103.
PMCID: PMC1450128
Changes produced by bound tryptophan in the ribosome peptidyl transferase center in response to TnaC, a nascent leader peptide
Luis Rogelio Cruz-Vera, Ming Gong, and Charles Yanofsky
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3598–3603. Published online 2006 February 27. doi: 10.1073/pnas.0600082103.
PMCID: PMC1450129
Mechanism of arylating quinone toxicity involving Michael adduct formation and induction of endoplasmic reticulum stress
Xinhe Wang, Beena Thomas, Rakesh Sachdeva, Linnea Arterburn, Lucy Frye, Patrick G. Hatcher, David G. Cornwell, and Jiyan Ma
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3604–3609. Published online 2006 February 27. doi: 10.1073/pnas.0510962103.
PMCID: PMC1450130
Electron trap for DNA-bound repair enzymes: A strategy for DNA-mediated signaling
Eylon Yavin, Eric D. A. Stemp, Valerie L. O’Shea, Sheila S. David, and Jacqueline K. Barton
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3610–3614. Published online 2006 February 27. doi: 10.1073/pnas.0600239103.
PMCID: PMC1450131
Biophysics
Structural determinants of selective α-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP
Chris Ulens, Ronald C. Hogg, Patrick H. Celie, Daniel Bertrand, Victor Tsetlin, August B. Smit, and Titia K. Sixma
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3615–3620. Published online 2006 February 27. doi: 10.1073/pnas.0507889103.
PMCID: PMC1450132
Structural basis for rodlet assembly in fungal hydrophobins
A. H. Y. Kwan, R. D. Winefield, M. Sunde, J. M. Matthews, R. G. Haverkamp, M. D. Templeton, and J. P. Mackay
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3621–3626. Published online 2006 February 28. doi: 10.1073/pnas.0505704103.
PMCID: PMC1533775
Projection structure of the human copper transporter CTR1 at 6-Å resolution reveals a compact trimer with a novel channel-like architecture
Stephen G. Aller and Vinzenz M. Unger
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3627–3632. Published online 2006 February 24. doi: 10.1073/pnas.0509929103.
PMCID: PMC1450133
Cell Biology
Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane
Francisca Vazquez, Satomi Matsuoka, William R. Sellers, Toshio Yanagida, Masahiro Ueda, and Peter N. Devreotes
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3633–3638. Published online 2006 February 28. doi: 10.1073/pnas.0510570103.
PMCID: PMC1450134
Neutrophil polarization: Spatiotemporal dynamics of RhoA activity support a self-organizing mechanism
Kit Wong, Olivier Pertz, Klaus Hahn, and Henry Bourne
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3639–3644. Published online 2006 February 28. doi: 10.1073/pnas.0600092103.
PMCID: PMC1450135
Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16INK4a
Isil Guney, Shirley Wu, and John M. Sedivy
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3645–3650. Published online 2006 February 28. doi: 10.1073/pnas.0600069103.
PMCID: PMC1450136
Developmental Biology
Tbx6-mediated Notch signaling controls somite-specific Mesp2 expression
Yukuto Yasuhiko, Seiki Haraguchi, Satoshi Kitajima, Yu Takahashi, Jun Kanno, and Yumiko Saga
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3651–3656. Published online 2006 February 27. doi: 10.1073/pnas.0508238103.
PMCID: PMC1450137
Ecology
From the Cover:
DNA barcodes reveal cryptic host-specificity within the presumed polyphagous members of a genus of parasitoid flies (Diptera: Tachinidae)
M. Alex Smith, Norman E. Woodley, Daniel H. Janzen, Winnie Hallwachs, and Paul D. N. Hebert
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3657–3662. Published online 2006 February 27. doi: 10.1073/pnas.0511318103.
PMCID: PMC1383497
Evolution
Clonal population structure and genetic diversity of Candida albicans in AIDS patients from Abidjan (Côte d’Ivoire)
François Nébavi, Francisco J. Ayala, François Renaud, Sébastien Bertout, Serge Eholié, Koné Moussa, Michèle Mallié, and Thierry de Meeûs
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3663–3668. Published online 2006 February 24. doi: 10.1073/pnas.0511328103.
PMCID: PMC1450139
Three RNA cells for ribosomal lineages and three DNA viruses to replicate their genomes: A hypothesis for the origin of cellular domain
Patrick Forterre
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3669–3674. Published online 2006 February 27. doi: 10.1073/pnas.0510333103.
PMCID: PMC1450140
Sodium channel genes and the evolution of diversity in communication signals of electric fishes: Convergent molecular evolution
Harold H. Zakon, Ying Lu, Derrick J. Zwickl, and David M. Hillis
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3675–3680. Published online 2006 February 27. doi: 10.1073/pnas.0600160103.
PMCID: PMC1450141
From the Cover:
New insights into myosin evolution and classification
Bernardo J. Foth, Marc C. Goedecke, and Dominique Soldati
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3681–3686. Published online 2006 February 27. doi: 10.1073/pnas.0506307103.
PMCID: PMC1533776
Genetics
Linkage analysis of quantitative traits for obesity, diabetes, hypertension, and dyslipidemia on the island of Kosrae, Federated States of Micronesia
Dvora Shmulewitz, Simon C. Heath, Maude L. Blundell, Zhihua Han, Ratnendra Sharma, Jacqueline Salit, Steven B. Auerbach, Stefano Signorini, Jan L. Breslow, Markus Stoffel, and Jeffrey M. Friedman
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3502–3509. Published online 2006 February 28. doi: 10.1073/pnas.0510156103.
PMCID: PMC1533774
The colorectal microRNAome
Jordan M. Cummins, Yiping He, Rebecca J. Leary, Ray Pagliarini, Luis A. Diaz, Jr., Tobias Sjoblom, Omer Barad, Zvi Bentwich, Anna E. Szafranska, Emmanuel Labourier, Christopher K. Raymond, Brian S. Roberts, Hartmut Juhl, Kenneth W. Kinzler, Bert Vogelstein, and Victor E. Velculescu
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3687–3692. Published online 2006 February 27. doi: 10.1073/pnas.0511155103.
PMCID: PMC1450142
Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice
Hiroko Koike, P. Alexander Arguello, Mirna Kvajo, Maria Karayiorgou, and Joseph A. Gogos
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3693–3697. Published online 2006 February 16. doi: 10.1073/pnas.0511189103.
PMCID: PMC1450143
Functional mapping of disease susceptibility loci using cell biology
Peter A. Antinozzi, Alejandro Garcia-Diaz, Chuan Hu, and James E. Rothman
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3698–3703. Published online 2006 February 28. doi: 10.1073/pnas.0510521103.
PMCID: PMC1533777
Genomic anatomy of the Tyrp1 (brown) deletion complex
Ian M. Smyth, Laurens Wilming, Angela W. Lee, Martin S. Taylor, Phillipe Gautier, Karen Barlow, Justine Wallis, Sancha Martin, Rebecca Glithero, Ben Phillimore, Sarah Pelan, Rob Andrew, Karen Holt, Ruth Taylor, Stuart McLaren, John Burton, Jonathon Bailey, Sarah Sims, Jan Squares, Bob Plumb, Ann Joy, Richard Gibson, James Gilbert, Elizabeth Hart, Gavin Laird, Jane Loveland, Jonathan Mudge, Charlie Steward, David Swarbreck, Jennifer Harrow, Philip North, Nicholas Leaves, John Greystrong, Maria Coppola, Shilpa Manjunath, Mark Campbell, Mark Smith, Gregory Strachan, Calli Tofts, Esther Boal, Victoria Cobley, Giselle Hunter, Christopher Kimberley, Daniel Thomas, Lee Cave-Berry, Paul Weston, Marc R. M. Botcherby, Sharon White, Ruth Edgar, Sally H. Cross, Marjan Irvani, Holger Hummerich, Eleanor H. Simpson, Dabney Johnson, Patricia R. Hunsicker, Peter F. R. Little, Tim Hubbard, R. Duncan Campbell, Jane Rogers, and Ian J. Jackson
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3704–3709. Published online 2006 February 27. doi: 10.1073/pnas.0600199103.
PMCID: PMC1450144
Checkpoint functions are required for normal S-phase progression in Saccharomyces cerevisiae RCAF- and CAF-I-defective mutants
Ellen S. Kats, Claudio P. Albuquerque, Huilin Zhou, and Richard D. Kolodner
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3710–3715. Published online 2006 February 24. doi: 10.1073/pnas.0511102103.
PMCID: PMC1533778
Constitutive expression of the Period1 gene impairs behavioral and molecular circadian rhythms
Rika Numano, Shin Yamazaki, Nanae Umeda, Tomonori Samura, Mitsugu Sujino, Ri-ichi Takahashi, Masatsugu Ueda, Akiko Mori, Kazunori Yamada, Yoshiyuki Sakaki, Shin-Ichi T. Inouye, Michael Menaker, and Hajime Tei
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3716–3721. Published online 2006 February 28. doi: 10.1073/pnas.0600060103.
PMCID: PMC1450145
Immunology
Mucosal and systemic adjuvant activity of alphavirus replicon particles
Joseph M. Thompson, Alan C. Whitmore, Jennifer L. Konopka, Martha L. Collier, Erin M. B. Richmond, Nancy L. Davis, Herman F. Staats, and Robert E. Johnston
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3722–3727. Published online 2006 February 27. doi: 10.1073/pnas.0600287103.
PMCID: PMC1383499
An ancient evolutionary origin of the Rag1/2 gene locus
Sebastian D. Fugmann, Cynthia Messier, Laura A. Novack, R. Andrew Cameron, and Jonathan P. Rast
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3728–3733. Published online 2006 February 27. doi: 10.1073/pnas.0509720103.
PMCID: PMC1450146
Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen
Haochu Huang, John F. Kearney, Michael J. Grusby, Christophe Benoist, and Diane Mathis
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3734–3739. Published online 2006 February 27. doi: 10.1073/pnas.0600214103.
PMCID: PMC1450147
Signals from OX40 regulate nuclear factor of activated T cells c1 and T cell helper 2 lineage commitment
Takanori So, Jianxun Song, Katsuji Sugie, Amnon Altman, and Michael Croft
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3740–3745. Published online 2006 February 24. doi: 10.1073/pnas.0600205103.
PMCID: PMC1450148
R5 and X4 HIV envelopes induce distinct gene expression profiles in primary peripheral blood mononuclear cells
Claudia Cicala, James Arthos, Elena Martinelli, Nina Censoplano, Catherine C. Cruz, Eva Chung, Sara M. Selig, Donald Van Ryk, Jun Yang, Shyla Jagannatha, Tae Wook Chun, Ping Ren, Richard A. Lempicki, and Anthony S. Fauci
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3746–3751. Published online 2006 February 27. doi: 10.1073/pnas.0511237103.
PMCID: PMC1533779
Medical Sciences
Reprogramming metastatic melanoma cells to assume a neural crest cell-like phenotype in an embryonic microenvironment
Paul M. Kulesa, Jennifer C. Kasemeier-Kulesa, Jessica M. Teddy, Naira V. Margaryan, Elisabeth A. Seftor, Richard E. B. Seftor, and Mary J. C. Hendrix
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3752–3757. Published online 2006 February 27. doi: 10.1073/pnas.0506977103.
PMCID: PMC1450149
Body-wide gene therapy of Duchenne muscular dystrophy in the mdx mouse model
Michela Alessandra Denti, Alessandro Rosa, Giuseppe D’Antona, Olga Sthandier, Fernanda Gabriella De Angelis, Carmine Nicoletti, Mariacarmela Allocca, Orietta Pansarasa, Valeria Parente, Antonio Musarò, Alberto Auricchio, Roberto Bottinelli, and Irene Bozzoni
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3758–3763. Published online 2006 February 24. doi: 10.1073/pnas.0508917103.
PMCID: PMC1450150
Conserved oligomeric Golgi complex subunit 1 deficiency reveals a previously uncharacterized congenital disorder of glycosylation type II
François Foulquier, Eliza Vasile, Els Schollen, Nico Callewaert, Tim Raemaekers, Dulce Quelhas, Jaak Jaeken, Philippa Mills, Bryan Winchester, Monty Krieger, Wim Annaert, and Gert Matthijs
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3764–3769. Published online 2006 February 28. doi: 10.1073/pnas.0507685103.
PMCID: PMC1450151
Familial clustering of site-specific cancer risks associated with BRCA1 and BRCA2 mutations in the Ashkenazi Jewish population
Sharon Simchoni, Eitan Friedman, Bella Kaufman, Ruth Gershoni-Baruch, Avi Orr-Urtreger, Inbal Kedar-Barnes, Ronit Shiri-Sverdlov, Efrat Dagan, Sigal Tsabari, Mordechai Shohat, Raphael Catane, Mary-Claire King, Amnon Lahad, and Ephrat Levy-Lahad
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3770–3774. Published online 2006 February 28. doi: 10.1073/pnas.0511301103.
PMCID: PMC1450152
A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase
Cynthia S. Collins, Jiyong Hong, Lisa Sapinoso, Yingyao Zhou, Zheng Liu, Kenneth Micklash, Peter G. Schultz, and Garret M. Hampton
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3775–3780. Published online 2006 February 28. doi: 10.1073/pnas.0600040103.
PMCID: PMC1383649
Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice
Eugene Trogan, Jonathan E. Feig, Snjezana Dogan, George H. Rothblat, Véronique Angeli, Frank Tacke, Gwendalyn J. Randolph, and Edward A. Fisher
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3781–3786. Published online 2006 March 1. doi: 10.1073/pnas.0511043103.
PMCID: PMC1450154
Selective irradiation of the vascular endothelium has no effect on the survival of murine intestinal crypt stem cells
Bradley W. Schuller, Peter J. Binns, Kent J. Riley, Ling Ma, M. Frederick Hawthorne, and Jeffrey A. Coderre
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3787–3792. Published online 2006 February 27. doi: 10.1073/pnas.0600133103.
PMCID: PMC1383492
Delayed testicular aging in pituitary adenylate cyclase-activating peptide (PACAP) null mice
Arnaud Lacombe, Vincent Lelievre, Charles E. Roselli, Wael Salameh, Yan-he Lue, Gregory Lawson, Jean-Marc Muller, James A. Waschek, and Eric Vilain
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3793–3798. Published online 2006 February 27. doi: 10.1073/pnas.0505827103.
PMCID: PMC1450155
Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism
Ayyakannu Ayyanan, Gianluca Civenni, Laura Ciarloni, Catherine Morel, Nathalie Mueller, Karine Lefort, Anna Mandinova, Wassim Raffoul, Maryse Fiche, Gian Paolo Dotto, and Cathrin Brisken
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3799–3804. Published online 2006 February 24. doi: 10.1073/pnas.0600065103.
PMCID: PMC1450156
From the Cover:
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
Brett D. Lindenbach, Philip Meuleman, Alexander Ploss, Thomas Vanwolleghem, Andrew J. Syder, Jane A. McKeating, Robert E. Lanford, Stephen M. Feinstone, Marian E. Major, Geert Leroux-Roels, and Charles M. Rice
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3805–3809. Published online 2006 February 16. doi: 10.1073/pnas.0511218103.
PMCID: PMC1533780
Microbiology
Dissecting toxin immunity in virus-infected killer yeast uncovers an intrinsic strategy of self-protection
Frank Breinig, Tanja Sendzik, Katrin Eisfeld, and Manfred J. Schmitt
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3810–3815. Published online 2006 February 27. doi: 10.1073/pnas.0510070103.
PMCID: PMC1533781
Global analysis of carbohydrate utilization by Lactobacillus acidophilus using cDNA microarrays
Rodolphe Barrangou, M. Andrea Azcarate-Peril, Tri Duong, Shannon B. Conners, Robert M. Kelly, and Todd R. Klaenhammer
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3816–3821. Published online 2006 February 27. doi: 10.1073/pnas.0511287103.
PMCID: PMC1533782
Selection of cervical keratinocytes containing integrated HPV16 associates with episome loss and an endogenous antiviral response
Mark R. Pett, M. Trent Herdman, Roger D. Palmer, Giles S. H. Yeo, Mahmud K. Shivji, Margaret A. Stanley, and Nicholas Coleman
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3822–3827. Published online 2006 February 27. doi: 10.1073/pnas.0600078103.
PMCID: PMC1383496
Quorum sensing and motility mediate interactions between Pseudomonas aeruginosa and Agrobacterium tumefaciens in biofilm cocultures
Dingding An, Thomas Danhorn, Clay Fuqua, and Matthew R. Parsek
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3828–3833. Published online 2006 February 28. doi: 10.1073/pnas.0511323103.
PMCID: PMC1533783
The partitioned Rhizobium etli genome: Genetic and metabolic redundancy in seven interacting replicons
Víctor González, Rosa I. Santamaría, Patricia Bustos, Ismael Hernández-González, Arturo Medrano-Soto, Gabriel Moreno-Hagelsieb, Sarath Chandra Janga, Miguel A. Ramírez, Verónica Jiménez-Jacinto, Julio Collado-Vides, and Guillermo Dávila
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3834–3839. Published online 2006 February 27. doi: 10.1073/pnas.0508502103.
PMCID: PMC1383491
A human cytomegalovirus antagonist of type I IFN-dependent signal transducer and activator of transcription signaling
Christina Paulus, Steffen Krauss, and Michael Nevels
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3840–3845. Published online 2006 February 23. doi: 10.1073/pnas.0600007103.
PMCID: PMC1533784
Heterotrophic Archaea dominate sedimentary subsurface ecosystems off Peru
Jennifer F. Biddle, Julius S. Lipp, Mark A. Lever, Karen G. Lloyd, Ketil B. Sørensen, Rika Anderson, Helen F. Fredricks, Marcus Elvert, Timothy J. Kelly, Daniel P. Schrag, Mitchell L. Sogin, Jean E. Brenchley, Andreas Teske, Christopher H. House, and Kai-Uwe Hinrichs
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3846–3851. Published online 2006 February 27. doi: 10.1073/pnas.0600035103.
PMCID: PMC1533785
Neuroscience
Running in pregnancy transiently increases postnatal hippocampal neurogenesis in the offspring
Anika Bick-Sander, Barbara Steiner, Susanne A. Wolf, Harish Babu, and Gerd Kempermann
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3852–3857. Published online 2006 March 6. doi: 10.1073/pnas.0502644103.
PMCID: PMC1389702
Between-subject transfer of emotional information evokes specific pattern of amygdala activation
Ewelina Knapska, Evgeni Nikolaev, Pawel Boguszewski, Grazyna Walasek, Janusz Blaszczyk, Leszek Kaczmarek, and Tomasz Werka
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3858–3862. Published online 2006 February 23. doi: 10.1073/pnas.0511302103.
PMCID: PMC1533786
Information-based functional brain mapping
Nikolaus Kriegeskorte, Rainer Goebel, and Peter Bandettini
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3863–3868. Published online 2006 February 28. doi: 10.1073/pnas.0600244103.
PMCID: PMC1383651
Brain cholesterol turnover required for geranylgeraniol production and learning in mice
Tiina J. Kotti, Denise M. O. Ramirez, Brad E. Pfeiffer, Kimberly M. Huber, and David W. Russell
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3869–3874. Published online 2006 February 27. doi: 10.1073/pnas.0600316103.
PMCID: PMC1450160
Prion infection of mouse neurospheres
Ranjit K. Giri, Rebecca Young, Rose Pitstick, Stephen J. DeArmond, Stanley B. Prusiner, and George A. Carlson
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3875–3880. Published online 2006 February 22. doi: 10.1073/pnas.0510902103.
PMCID: PMC1533787
Elevated cholecystokininergic tone constitutes an important molecular/neuronal mechanism for the expression of anxiety in the mouse
Qian Chen, Akira Nakajima, Corbin Meacham, and Ya-Ping Tang
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3881–3886. Published online 2006 February 28. doi: 10.1073/pnas.0505407103.
PMCID: PMC1383652
Neuroprotection by pharmacologic blockade of the GAPDH death cascade
Makoto R. Hara, Bobby Thomas, Matthew B. Cascio, Byoung-Il Bae, Lynda D. Hester, Valina L. Dawson, Ted M. Dawson, Akira Sawa, and Solomon H. Snyder
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3887–3889. Published online 2006 February 27. doi: 10.1073/pnas.0511321103.
PMCID: PMC1450161
From the Cover:
Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors
Masayuki Akimoto, Hong Cheng, Dongxiao Zhu, Joseph A. Brzezinski, Ritu Khanna, Elena Filippova, Edwin C. T. Oh, Yuezhou Jing, Jose-Luis Linares, Matthew Brooks, Sepideh Zareparsi, Alan J. Mears, Alfred Hero, Tom Glaser, and Anand Swaroop
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3890–3895. Published online 2006 February 27. doi: 10.1073/pnas.0508214103.
PMCID: PMC1383502
Ciliary neurotrophic factor (CNTF) for human retinal degeneration: Phase I trial of CNTF delivered by encapsulated cell intraocular implants
Paul A. Sieving, Rafael C. Caruso, Weng Tao, Hanna R. Coleman, Darby J. S. Thompson, Keri R. Fullmer, and Ronald A. Bush
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3896–3901. Published online 2006 February 27. doi: 10.1073/pnas.0600236103.
PMCID: PMC1383495
Retinoic acid is required early during adult neurogenesis in the dentate gyrus
Sharoni Jacobs, D. Chichung Lie, Kathleen L. DeCicco, Yanhong Shi, Luigi M. DeLuca, Fred H. Gage, and Ronald M. Evans
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3902–3907. Published online 2006 February 27. doi: 10.1073/pnas.0511294103.
PMCID: PMC1450163
Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action
Kyoung-Shim Kim, Ko-Woon Lee, Kang-Woo Lee, Joo-Young Im, Ji Yeoun Yoo, Seung-Woo Kim, Ja-Kyeong Lee, Eric J. Nestler, and Pyung-Lim Han
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3908–3913. Published online 2006 February 28. doi: 10.1073/pnas.0508812103.
PMCID: PMC1533788
Pharmacology
Reversal to cisplatin sensitivity in recurrent human ovarian cancer cells by NCX-4016, a nitro derivative of aspirin
Anna Bratasz, Nathan M. Weir, Narasimham L. Parinandi, Jay L. Zweier, Rajagopalan Sridhar, Louis J. Ignarro, and Periannan Kuppusamy
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3914–3919. Published online 2006 February 23. doi: 10.1073/pnas.0511250103.
PMCID: PMC1450164
Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor
Takeshi Inagaki, Antonio Moschetta, Youn-Kyoung Lee, Li Peng, Guixiang Zhao, Michael Downes, Ruth T. Yu, John M. Shelton, James A. Richardson, Joyce J. Repa, David J. Mangelsdorf, and Steven A. Kliewer
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3920–3925. Published online 2006 February 10. doi: 10.1073/pnas.0509592103.
PMCID: PMC1450165
Physiology
cAMP regulates plasma membrane vacuolar-type H+-ATPase assembly and activity in blowfly salivary glands
Petra Dames, Bernhard Zimmermann, Ruth Schmidt, Julia Rein, Martin Voss, Bettina Schewe, Bernd Walz, and Otto Baumann
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3926–3931. Published online 2006 February 28. doi: 10.1073/pnas.0600011103.
PMCID: PMC1450166
Cyclosporin and Timothy syndrome increase mode 2 gating of CaV1.2 calcium channels through aberrant phosphorylation of S6 helices
Christian Erxleben, Yanhong Liao, Saverio Gentile, David Chin, Claudio Gomez-Alegria, Yasuo Mori, Lutz Birnbaumer, and David L. Armstrong
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3932–3937. Published online 2006 February 28. doi: 10.1073/pnas.0511322103.
PMCID: PMC1533789
Cortisol levels and very early pregnancy loss in humans
Pablo A. Nepomnaschy, Kathleen B. Welch, Daniel S. McConnell, Bobbi S. Low, Beverly I. Strassmann, and Barry G. England
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3938–3942. Published online 2006 February 22. doi: 10.1073/pnas.0511183103.
PMCID: PMC1533790
Social Sciences
Anthropology
Body size, body proportions, and encephalization in a Middle Pleistocene archaic human from northern China
Karen R. Rosenberg, Lü Zuné, and Christopher B. Ruff
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3552–3556. Published online 2006 February 27. doi: 10.1073/pnas.0508681103.
PMCID: PMC1450121
Cortisol levels and very early pregnancy loss in humans
Pablo A. Nepomnaschy, Kathleen B. Welch, Daniel S. McConnell, Bobbi S. Low, Beverly I. Strassmann, and Barry G. England
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3938–3942. Published online 2006 February 22. doi: 10.1073/pnas.0511183103.
PMCID: PMC1533790
Sustainability Science
Geography and macroeconomics: New data and new findings
William D. Nordhaus
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3510–3517. Published online 2006 February 10. doi: 10.1073/pnas.0509842103.
PMCID: PMC1363683
Pharmacology
Correction for Robert et al., The antimalarial drug artemisinin alkylates heme in infected mice
Proc Natl Acad Sci U S A. 2006 March 7; 103(10): 3943. doi: 10.1073/pnas.0600629103.
PMCID: PMC1533791
Corrects: Anne Robert, et al. The antimalarial drug artemisinin alkylates heme in infected mice. Proc Natl Acad Sci U S A. 2005 September 20; 102(38): 13676–13680.
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