| | This journal provides immediate access to some articles. Commentaries Turning tRNA upside down: When aminoacylation is not a prerequisite to protein synthesis Michael Ibba and Christopher Francklyn PMCID: PMC419631 Hot new virus, deep connections Roger W. Hendrix PMCID: PMC419632 Resolving the biological role of the Rhesus (Rh) proteins of red blood cells with the aid of a green alga Aaron Kaplan, Judy Lieman-Hurwitz, and Dan Tchernov PMCID: PMC419633 Physical Sciences Applied Mathematics From the Cover:
Diffusion-based method for producing density-equalizing maps Michael T. Gastner and M. E. J. Newman PMCID: PMC419634 Chemistry Amplified fluorescence sensing of protease activity with conjugated polyelectrolytes Mauricio R. Pinto and Kirk S. Schanze PMCID: PMC419635 Fluorescent-conjugated polymer superquenching facilitates highly sensitive detection of proteases Sriram Kumaraswamy, Troy Bergstedt, Xiaobo Shi, Frauke Rininsland, Stuart Kushon, Wensheng Xia, Kevin Ley, Komandoor Achyuthan, Duncan McBranch, and David Whitten PMCID: PMC419636 Engineering Structural and functional imaging of 3D microfluidic mixers using optical coherence tomography Chuanwu Xi, Daniel L. Marks, Devang S. Parikh, Lutgarde Raskin, and Stephen A. Boppart PMCID: PMC419637 Mathematics Consistency of a counterexample to Naimark's problem Charles Akemann and Nik Weaver PMCID: PMC419638 Biological Sciences Agricultural Sciences Contamination of refuges by Bacillus thuringiensis toxin genes from transgenic maize Charles F. Chilcutt and Bruce E. Tabashnik PMCID: PMC419639 Biochemistry From the Cover:
An aminoacyl-tRNA synthetase-like protein encoded by the Escherichia coli yadB gene glutamylates specifically tRNAAsp Daniel Y. Dubois, Mickaël Blaise, Hubert D. Becker, Valérie Campanacci, Gérard Keith, Richard Giegé, Christian Cambillau, Jacques Lapointe, and Daniel Kern PMCID: PMC419640 From the Cover:
A truncated aminoacyl–tRNA synthetase modifies RNA Juan C. Salazar, Alexandre Ambrogelly, Pamela F. Crain, James A. McCloskey, and Dieter Söll PMCID: PMC419641 Blarina toxin, a mammalian lethal venom from the short-tailed shrew Blarina brevicauda: Isolation and characterization Masaki Kita, Yasuo Nakamura, Yuushi Okumura, Satoshi D. Ohdachi, Yuichi Oba, Michiyasu Yoshikuni, Hiroshi Kido, and Daisuke Uemura PMCID: PMC419642 Inducing and modulating anisotropic DNA bends by pseudocomplementary peptide nucleic acids Heiko Kuhn, Dmitry I. Cherny, Vadim V. Demidov, and Maxim D. Frank-Kamenetskii PMCID: PMC419643 Selective inhibition of calcineurin-NFAT signaling by blocking protein–protein interaction with small organic molecules Michael H. A. Roehrl, Sunghyun Kang, José Aramburu, Gerhard Wagner, Anjana Rao, and Patrick G. Hogan PMCID: PMC419644 Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein α-subunit Celestine J. Thomas, Xinlin Du, PiLong Li, Ying Wang, Elliott M. Ross, and Stephen R. Sprang PMCID: PMC419645 An expanded genetic code with a functional quadruplet codon J. Christopher Anderson, Ning Wu, Stephen W. Santoro, Vishva Lakshman, David S. King, and Peter G. Schultz PMCID: PMC419646 Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II Subhrangsu S. Mandal, Chun Chu, Tadashi Wada, Hiroshi Handa, Aaron J. Shatkin, and Danny Reinberg PMCID: PMC419647 The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-α/β-induced ubiquitin-like protein Chen Zhao, Sylvie L. Beaudenon, Melissa L. Kelley, M. Brett Waddell, Weiming Yuan, Brenda A. Schulman, Jon M. Huibregtse, and Robert M. Krug PMCID: PMC419648 SecB is a bona fide generalized chaperone in Escherichia coli Ronald S. Ullers, Joen Luirink, Nellie Harms, Françoise Schwager, Costa Georgopoulos, and Pierre Genevaux PMCID: PMC419649 Reduction in DNA-binding affinity of Cys2His2 zinc finger proteins by linker phosphorylation Derek Jantz and Jeremy M. Berg PMCID: PMC419650 Biophysics Automated structure prediction of weakly homologous proteins on a genomic scale Yang Zhang and Jeffrey Skolnick PMCID: PMC419651 Bacteriophage capsids: Tough nanoshells with complex elastic properties I. L. Ivanovska, P. J. de Pablo, B. Ibarra, G. Sgalari, F. C. MacKintosh, J. L. Carrascosa, C. F. Schmidt, and G. J. L. Wuite PMCID: PMC419652 Scattered Hammond plots reveal second level of site-specific information in protein folding: ![[var phi]](corehtml/pmc/pmcents/x03C6.gif) ′ (β ‡) Linda Hedberg and Mikael Oliveberg PMCID: PMC419653 Cell Biology From the Cover:
TorsinA in the nuclear envelope Teresa V. Naismith, John E. Heuser, Xandra O. Breakefield, and Phyllis I. Hanson PMCID: PMC419654 Rational design and characterization of a Rac GTPase-specific small molecule inhibitor Yuan Gao, J. Bradley Dickerson, Fukun Guo, Jie Zheng, and Yi Zheng PMCID: PMC419655 DNA end joining becomes less efficient and more error-prone during cellular senescence Andrei Seluanov, David Mittelman, Olivia M. Pereira-Smith, John H. Wilson, and Vera Gorbunova PMCID: PMC419656 Endogenous NO regulates superoxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase Miriam Palacios-Callender, Marisol Quintero, Veronica S. Hollis, Roger J. Springett, and Salvador Moncada PMCID: PMC419657 Developmental Biology The effect of interspecific oocytes on demethylation of sperm DNA Nathalie Beaujean, Jane E. Taylor, Michelle McGarry, John O. Gardner, Ian Wilmut, Pasqualino Loi, Grazyna Ptak, Cesare Galli, Giovanna Lazzari, Adrian Bird, Lorraine E. Young, and Richard R. Meehan PMCID: PMC419658 Cdx2 is essential for axial elongation in mouse development Kallayanee Chawengsaksophak, Wim de Graaff, Janet Rossant, Jacqueline Deschamps, and Felix Beck PMCID: PMC419659 Ecology Reversing introduced species effects: Experimental removal of introduced fish leads to rapid recovery of a declining frog Vance T. Vredenburg PMCID: PMC419660 Neutrality, niches, and dispersal in a temperate forest understory Benjamin Gilbert and Martin J. Lechowicz PMCID: PMC419661 Evolution Molecular evidence links cryptic diversification in polar planktonic protists to Quaternary climate dynamics Kate F. Darling, Michal Kucera, Carol J. Pudsey, and Christopher M. Wade PMCID: PMC419662 Genetics Similar gene expression patterns characterize aging and oxidative stress in Drosophila melanogaster Gary N. Landis, Diana Abdueva, Dmitriy Skvortsov, Junsheng Yang, Beth E. Rabin, James Carrick, Simon Tavaré, and John Tower PMCID: PMC419663 Immunology HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation Angela Granelli-Piperno, Angelika Golebiowska, Christine Trumpfheller, Frederick P. Siegal, and Ralph M. Steinman PMCID: PMC419664 Crystal structure of the human T cell receptor CD3εγ heterodimer complexed to the therapeutic mAb OKT3 Lars Kjer-Nielsen, Michelle A. Dunstone, Lyudmila Kostenko, Lauren K. Ely, Travis Beddoe, Nicole A. Mifsud, Anthony W. Purcell, Andrew G. Brooks, James McCluskey, and Jamie Rossjohn PMCID: PMC419665 Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells Yanan Zhu, Bradley J. Swanson, Michael Wang, David A. Hildeman, Brian C. Schaefer, Xinqi Liu, Hiroyuki Suzuki, Katsuyoshi Mihara, John Kappler, and Philippa Marrack PMCID: PMC419666 Medical Sciences Role for glyoxalase I in Alzheimer's disease Feng Chen, M. Axel Wollmer, Frederic Hoerndli, Gerald Münch, Björn Kuhla, Evgeny I. Rogaev, Magdalini Tsolaki, Andreas Papassotiropoulos, and Jürgen Götz PMCID: PMC419667 Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells Meera Srivastava, Ofer Eidelman, Jian Zhang, Cloud Paweletz, Hung Caohuy, QingFeng Yang, Kenneth A. Jacobson, Eliahu Heldman, Wei Huang, Catherine Jozwik, Bette S. Pollard, and Harvey B. Pollard PMCID: PMC419668 Albumin mediates the transcytosis of myeloperoxidase by means of caveolae in endothelial cells Chinnaswamy Tiruppathi, Tabassum Naqvi, Yubin Wu, Stephen M. Vogel, Richard D. Minshall, and Asrar B. Malik PMCID: PMC419669 Neutralizing antibodies to hepatitis C virus (HCV) in immune globulins derived from anti-HCV-positive plasma Mei-ying W. Yu, Birke Bartosch, Pei Zhang, Zheng-ping Guo, Paula M. Renzi, Li-ming Shen, Christelle Granier, Stephen M. Feinstone, François-Loïc Cosset, and Robert H. Purcell PMCID: PMC419670 Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase Jeffrey B. Cheng, Michael A. Levine, Norman H. Bell, David J. Mangelsdorf, and David W. Russell PMCID: PMC419671 Microbiology From the Cover:
The structure of a thermophilic archaeal virus shows a double-stranded DNA viral capsid type that spans all domains of life George Rice, Liang Tang, Kenneth Stedman, Francisco Roberto, Josh Spuhler, Eric Gillitzer, John E. Johnson, Trevor Douglas, and Mark Young PMCID: PMC419672 Reconstitution of retroviral fusion and uncoating in a cell-free system Shakti Narayan and John A. T. Young PMCID: PMC419673 Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion Mark S. Sundrud, Victor J. Torres, Derya Unutmaz, and Timothy L. Cover PMCID: PMC419674 Lipids in the inner membrane of dormant spores of Bacillus species are largely immobile Ann E. Cowan, Elizabeth M. Olivastro, Dennis E. Koppel, Charles A. Loshon, Barbara Setlow, and Peter Setlow PMCID: PMC419675 Neuroscience Plasticity and tuning by visual feedback of the stability of a neural integrator Guy Major, Robert Baker, Emre Aksay, Brett Mensh, H. Sebastian Seung, and David W. Tank PMCID: PMC419676 Plasticity and tuning of the time course of analog persistent firing in a neural integrator Guy Major, Robert Baker, Emre Aksay, H. Sebastian Seung, and David W. Tank PMCID: PMC419677 Role of metabotropic glutamate receptors in oligodendrocyte excitotoxicity and oxidative stress Wenbin Deng, Hong Wang, Paul A. Rosenberg, Joseph J. Volpe, and Frances E. Jensen PMCID: PMC419678 An effective kinetic representation of fluctuation-driven neuronal networks with application to simple and complex cells in visual cortex David Cai, Louis Tao, Michael Shelley, and David W. McLaughlin PMCID: PMC419679 Temporal and regional differences in the olfactory proteome as a consequence of MeCP2 deficiency Valéry Matarazzo and Gabriele V. Ronnett PMCID: PMC419680 Positioning of the α-subunit isoforms confers a functional signature to γ-aminobutyric acid type A receptors Frédéric Minier and Erwin Sigel PMCID: PMC419681 Pharmacology Brain renin-angiotensin system blockade by systemically active aminopeptidase A inhibitors: A potential treatment of salt-dependent hypertension Marie-Claude Fournie-Zaluski, Celine Fassot, Bruno Valentin, Dragan Djordjijevic, Annabelle Reaux-Le Goazigo, Pierre Corvol, Bernard P. Roques, and Catherine Llorens-Cortes PMCID: PMC419682 Dissociation of rewarding and dopamine transporter-mediated properties of amphetamine Evgeny A. Budygin, Mark S. Brodie, Tatyana D. Sotnikova, Yolanda Mateo, Carrie E. John, Michel Cyr, Raul R. Gainetdinov, and Sara R. Jones PMCID: PMC419683 Physiology From the Cover:
Lack of the Rhesus protein Rh1 impairs growth of the green alga Chlamydomonas reinhardtii at high CO2 Eric Soupene, William Inwood, and Sydney Kustu PMCID: PMC419684 Haploinsufficiency of kelch-like protein homolog 10 causes infertility in male mice Wei Yan, Lang Ma, Kathleen H. Burns, and Martin M. Matzuk PMCID: PMC419685 NO stimulation of ATP-sensitive potassium channels: Involvement of Ras/mitogen-activated protein kinase pathway and contribution to neuroprotection Yu-Fung Lin, Kimberly Raab-Graham, Yuh Nung Jan, and Lily Yeh Jan PMCID: PMC419686 Plant Biology Frequent fusion and fission of plant mitochondria with unequal nucleoid distribution Shin-ichi Arimura, Junko Yamamoto, Gen Paul Aida, Mikio Nakazono, and Nobuhiro Tsutsumi PMCID: PMC419687 Differential metabolic networks unravel the effects of silent plant phenotypes Wolfram Weckwerth, Marcelo Ehlers Loureiro, Kathrin Wenzel, and Oliver Fiehn PMCID: PMC419688 Enlarged meristems and delayed growth in plp mutants result from lack of CaaX prenyltransferases Mark P. Running, Meirav Lavy, Hasana Sternberg, Arnaud Galichet, Wilhelm Gruissem, Sarah Hake, Naomi Ori, and Shaul Yalovsky PMCID: PMC419689 Arabidopsis thaliana DNA gyrase is targeted to chloroplasts and mitochondria Melisa K. Wall, Lesley A. Mitchenall, and Anthony Maxwell PMCID: PMC419690 Floral homeotic genes are targets of gibberellin signaling in flower development Hao Yu, Toshiro Ito, Yuanxiang Zhao, Jinrong Peng, Prakash Kumar, and Elliot M. Meyerowitz PMCID: PMC419691 Metabolic engineering with Dof1 transcription factor in plants: Improved nitrogen assimilation and growth under low-nitrogen conditions Shuichi Yanagisawa, Ai Akiyama, Hiroaki Kisaka, Hirofumi Uchimiya, and Tetuya Miwa PMCID: PMC419692 Corrections Proc Natl Acad Sci U S A. 2004 May 18; 101(20): 7839. Published online 2004 May 5. doi: 10.1073/pnas.0308117101.PMCID: PMC419693 Corrects: Luc D. B. Gigord, et al. Negative frequency-dependent selection maintains a dramatic
flower color polymorphism in the rewardless orchid
Dactylorhiza sambucina (L.) Soò. Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6253–6255. Proc Natl Acad Sci U S A. 2004 May 18; 101(20): 7840. Published online 2004 May 6. doi: 10.1073/pnas.0402364101.PMCID: PMC419694 Corrects: David A. Martin, et al. Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia. Proc Natl Acad Sci U S A. 1999 April 13; 96(8): 4552–4557. |
