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Volume 103(1);  January 3, 2006
In This Issue
This Week in PNAS
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 1–2. doi: 10.1073/iti0106103.
PMCID: PMC1324970
Commentaries
More barrels from the viral tree of life
Roger M. Burnett
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 3–4. Published online 2005 December 27. doi: 10.1073/pnas.0509852102.
PMCID: PMC1325008
Mesozoic aviary takes form
Alan Feduccia
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 5–6. Published online 2005 December 27. doi: 10.1073/pnas.0509970102.
PMCID: PMC1325012
Profile
Profile of Xiaodong Wang
Nick Zagorski
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 7–9. Published online 2005 December 27. doi: 10.1073/pnas.0509187103.
PMCID: PMC1324996
Physical Sciences
Chemistry
Complementary base-pair-facilitated electron tunneling for electrically pinpointing complementary nucleobases
Takahito Ohshiro and Yoshio Umezawa
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 10–14. Published online 2005 December 22. doi: 10.1073/pnas.0506130103.
PMCID: PMC1324978
Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen
Cheng-Yuan Huang, Desiree A. Thayer, Aileen Y. Chang, Michael D. Best, Julia Hoffmann, Steve Head, and Chi-Huey Wong
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 15–20. Published online 2005 December 22. doi: 10.1073/pnas.0509693102.
PMCID: PMC1325001
Computer Sciences
Mapping of orthologous genes in the context of biological pathways: An application of integer programming
Fenglou Mao, Zhengchang Su, Victor Olman, Phuongan Dam, Zhijie Liu, and Ying Xu
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 129–134. Published online 2005 December 22. doi: 10.1073/pnas.0509737102.
PMCID: PMC1325003
Global landscape of recent inferred Darwinian selection for Homo sapiens
Eric T. Wang, Greg Kodama, Pierre Baldi, and Robert K. Moyzis
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 135–140. Published online 2005 December 21. doi: 10.1073/pnas.0509691102.
PMCID: PMC1317879
Biological Sciences
Biochemistry
From the Cover:
Protein fucosylation regulates synapsin Ia/Ib expression and neuronal morphology in primary hippocampal neurons
Heather E. Murrey, Cristal I. Gama, Stacey A. Kalovidouris, Wen.-I. Luo, Edward M. Driggers, Barbara Porton, and Linda C. Hsieh-Wilson
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 21–26. Published online 2005 December 22. doi: 10.1073/pnas.0503381102.
PMCID: PMC1324972
From the Cover:
Crystal structure of phycocyanobilin:ferredoxin oxidoreductase in complex with biliverdin IXα, a key enzyme in the biosynthesis of phycocyanobilin
Yoshinori Hagiwara, Masakazu Sugishima, Yasuhiro Takahashi, and Keiichi Fukuyama
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 27–32. Published online 2005 December 27. doi: 10.1073/pnas.0507266103.
PMCID: PMC1324987
Evidence for the direct involvement of βTrCP in Gli3 protein processing
Baolin Wang and Yanyun Li
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 33–38. Published online 2005 December 21. doi: 10.1073/pnas.0509927103.
PMCID: PMC1325010
Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic
Letizia Brandi, Attilio Fabbretti, Anna La Teana, Monica Abbondi, Daniele Losi, Stefano Donadio, and Claudio O. Gualerzi
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 39–44. Published online 2005 December 27. doi: 10.1073/pnas.0507740102.
PMCID: PMC1324990
PDSM, a motif for phosphorylation-dependent SUMO modification
Ville Hietakangas, Julius Anckar, Henri A. Blomster, Mitsuaki Fujimoto, Jorma J. Palvimo, Akira Nakai, and Lea Sistonen
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 45–50. Published online 2005 December 21. doi: 10.1073/pnas.0503698102.
PMCID: PMC1324973
Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: A HEAT-repeat-containing metalloenzyme
Jong-Hwan Park, L. Aravind, Edith C. Wolff, Jörn Kaevel, Yeon Sook Kim, and Myung Hee Park
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 51–56. Published online 2005 December 21. doi: 10.1073/pnas.0509348102.
PMCID: PMC1324997
V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors
O. M. Grbovic, A. D. Basso, A. Sawai, Q. Ye, P. Friedlander, D. Solit, and N. Rosen
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 57–62. Published online 2005 December 21. doi: 10.1073/pnas.0609973103.
PMCID: PMC1325013
Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2α RNA-dependent protein kinase
Qiaozhu Su, Shuo Wang, Dionissios Baltzis, Li-Ke Qu, Andrew Hoi-Tao Wong, and Antonis E. Koromilas
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 63–68. Published online 2005 December 22. doi: 10.1073/pnas.0508207103.
PMCID: PMC1324992
Intraprotein transfer of the quinone analogue inhibitor 2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone in the cytochrome b6f complex
Jiusheng Yan, Genji Kurisu, and William A. Cramer
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 69–74. Published online 2005 December 21. doi: 10.1073/pnas.0504909102.
PMCID: PMC1324977
CYP27B1 null mice with LacZreporter gene display no 25-hydroxyvitamin D3-1α-hydroxylase promoter activity in the skin
Janeen L. Vanhooke, Jean M. Prahl, Christine Kimmel-Jehan, Monica Mendelsohn, Eric W. Danielson, Kevin D. Healy, and Hector F. DeLuca
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 75–80. Published online 2005 December 21. doi: 10.1073/pnas.0509734103.
PMCID: PMC1325002
A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme
Dirk Roeser, Andrea Preusser-Kunze, Bernhard Schmidt, Kathrin Gasow, Julia G. Wittmann, Thomas Dierks, Kurt von Figura, and Markus Georg Rudolph
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 81–86. Published online 2005 December 20. doi: 10.1073/pnas.0507592102.
PMCID: PMC1324989
Biophysics
Two independent mechanical events in the interaction cycle of skeletal muscle myosin with actin
M. Capitanio, M. Canepari, P. Cacciafesta, V. Lombardi, R. Cicchi, M. Maffei, F. S. Pavone, and R. Bottinelli
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 87–92. Published online 2005 December 21. doi: 10.1073/pnas.0506830102.
PMCID: PMC1324983
Multiple stepwise refolding of immunoglobulin domain I27 upon force quench depends on initial conditions
Mai Suan Li, Chin-Kun Hu, Dmitri K. Klimov, and D. Thirumalai
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 93–98. Published online 2005 December 22. doi: 10.1073/pnas.0503758103.
PMCID: PMC1324974
Determination of an ensemble of structures representing the intermediate state of the bacterial immunity protein Im7
Joerg Gsponer, Harri Hopearuoho, Sara B.-M. Whittaker, Graham R. Spence, Geoffrey R. Moore, Emanuele Paci, Sheena E. Radford, and Michele Vendruscolo
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 99–104. Published online 2005 December 21. doi: 10.1073/pnas.0508667102.
PMCID: PMC1324994
Cell Biology
From the Cover:
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production
Michal Safran, William Y. Kim, Fionnuala O'Connell, Lee Flippin, Volkmar Günzler, James W. Horner, Ronald A. DePinho, and William G. Kaelin, Jr.
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 105–110. Published online 2005 December 22. doi: 10.1073/pnas.0509459103.
PMCID: PMC1324998
PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry
Matthias Groszer, Rebecca Erickson, Deirdre D. Scripture-Adams, Joseph D. Dougherty, Janel Le Belle, Jerome A. Zack, Daniel H. Geschwind, Xin Liu, Harley I. Kornblum, and Hong Wu
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 111–116. Published online 2005 December 22. doi: 10.1073/pnas.0509939103.
PMCID: PMC1325011
Environmental Sciences
Predicting microbial species richness
Sun-Hee Hong, John Bunge, Sun-Ok Jeon, and Slava S. Epstein
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 117–122. Published online 2005 December 20. doi: 10.1073/pnas.0507245102.
PMCID: PMC1324986
Genetics
Atherosclerosis quantitative trait loci are sex- and lineage-dependent in an intercross of C57BL/6 and FVB/N low-density lipoprotein receptor–/– mice
Daniel Teupser, Marietta Tan, Adam D. Persky, and Jan L. Breslow
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 123–128. Published online 2005 December 27. doi: 10.1073/pnas.0509570102.
PMCID: PMC1324999
Mapping of orthologous genes in the context of biological pathways: An application of integer programming
Fenglou Mao, Zhengchang Su, Victor Olman, Phuongan Dam, Zhijie Liu, and Ying Xu
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 129–134. Published online 2005 December 22. doi: 10.1073/pnas.0509737102.
PMCID: PMC1325003
Global landscape of recent inferred Darwinian selection for Homo sapiens
Eric T. Wang, Greg Kodama, Pierre Baldi, and Robert K. Moyzis
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 135–140. Published online 2005 December 21. doi: 10.1073/pnas.0509691102.
PMCID: PMC1317879
Immunology
Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen
Cheng-Yuan Huang, Desiree A. Thayer, Aileen Y. Chang, Michael D. Best, Julia Hoffmann, Steve Head, and Chi-Huey Wong
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 15–20. Published online 2005 December 22. doi: 10.1073/pnas.0509693102.
PMCID: PMC1325001
Internalization and phagosome escape required for Francisella to induce human monocyte IL-1β processing and release
Mikhail A. Gavrilin, Imad J. Bouakl, Nina L. Knatz, Michelle D. Duncan, Mark W. Hall, John S. Gunn, and Mark D. Wewers
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 141–146. Published online 2005 December 22. doi: 10.1073/pnas.0504271103.
PMCID: PMC1324976
Perforin-dependent elimination of dendritic cells regulates the expansion of antigen-specific CD8+ T cells in vivo
Jianping Yang, Stephanie P. Huck, Rebecca S. McHugh, Ian F. Hermans, and Franca Ronchese
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 147–152. Published online 2005 December 22. doi: 10.1073/pnas.0509054103.
PMCID: PMC1324995
Regulation of dendritic cell maturation and function by Bruton's tyrosine kinase via IL-10 and Stat3
Yuko Kawakami, Naoki Inagaki, Shahram Salek-Ardakani, Jiro Kitaura, Hiroyuki Tanaka, Koichi Nagao, Yu Kawakami, Wenbin Xiao, Hiroichi Nagai, Michael Croft, and Toshiaki Kawakami
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 153–158. Published online 2005 December 21. doi: 10.1073/pnas.0509784103.
PMCID: PMC1325006
Medical Sciences
Bisphosphonate-mediated gene vector delivery from the metal surfaces of stents
Ilia Fishbein, Ivan S. Alferiev, Origene Nyanguile, Richard Gaster, John M. Vohs, Gordon S. Wong, Howard Felderman, I-Wei Chen, Hoon Choi, Robert L. Wilensky, and Robert J. Levy
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 159–164. Published online 2005 December 21. doi: 10.1073/pnas.0502945102.
PMCID: PMC1317877
Microbiology
The Bacillus subtilis spore coat provides “eat resistance” during phagocytic predation by the protozoan Tetrahymena thermophila
Lawrence A. Klobutcher, Katerina Ragkousi, and Peter Setlow
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 165–170. Published online 2005 December 21. doi: 10.1073/pnas.0507121102.
PMCID: PMC1324984
Multiple sensors control reciprocal expression of Pseudomonas aeruginosa regulatory RNA and virulence genes
Isabelle Ventre, Andrew L. Goodman, Isabelle Vallet-Gely, Perrine Vasseur, Chantal Soscia, Søren Molin, Sophie Bleves, Andrée Lazdunski, Stephen Lory, and Alain Filloux
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 171–176. Published online 2005 December 22. doi: 10.1073/pnas.0507407103.
PMCID: PMC1324988
Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria
Frank P. Mockenhaupt, Jakob P. Cramer, Lutz Hamann, Miriam S. Stegemann, Jana Eckert, Na-Ri Oh, Rowland N. Otchwemah, Ekkehart Dietz, Stephan Ehrhardt, Nicolas W. J. Schröder, Ulrich Bienzle, and Ralf R. Schumann
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 177–182. Published online 2005 December 21. doi: 10.1073/pnas.0506803102.
PMCID: PMC1324982
Neuroscience
Silent plateau potentials, rhythmic bursts, and pacemaker firing: Three patterns of activity that coexist in quadristable subthalamic neurons
Jason I. Kass and Isabelle M. Mintz
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 183–188. Published online 2005 December 22. doi: 10.1073/pnas.0506781102.
PMCID: PMC1324981
Neural activity in speech-sensitive auditory cortex during silence
M. D. Hunter, S. B. Eickhoff, T. W. R. Miller, T. F. D. Farrow, I. D. Wilkinson, and P. W. R. Woodruff
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 189–194. Published online 2005 December 21. doi: 10.1073/pnas.0506268103.
PMCID: PMC1317878
Loss of the limbic mineralocorticoid receptor impairs behavioral plasticity
Stefan Berger, David P. Wolfer, Oliver Selbach, Heike Alter, Gitta Erdmann, Holger M. Reichardt, Aisa N. Chepkova, Hans Welzl, Helmut L. Haas, Hans-Peter Lipp, and Günther Schütz
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 195–200. Published online 2005 December 20. doi: 10.1073/pnas.0503878102.
PMCID: PMC1324975
From the Cover:
Inhibitory control by an integral feedback signal in prefrontal cortex: A model of discrimination between sequential stimuli
Paul Miller and Xiao-Jing Wang
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 201–206. Published online 2005 December 21. doi: 10.1073/pnas.0508072103.
PMCID: PMC1324991
Stimulation of muscarinic receptors mimics experience-dependent plasticity in the honey bee brain
Nyla Ismail, Gene E. Robinson, and Susan E. Fahrbach
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 207–211. Published online 2005 December 22. doi: 10.1073/pnas.0508318102.
PMCID: PMC1324993
Pharmacology
Giα and Gβ subunits both define selectivity of G protein activation by α2-adrenergic receptors
Scott K. Gibson and Alfred G. Gilman
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 212–217. Published online 2005 December 21. doi: 10.1073/pnas.0509763102.
PMCID: PMC1325004
Inositols prevent and reverse endothelial dysfunction in diabetic rat and rabbit vasculature metabolically and by scavenging superoxide
N. R. F. Nascimento, L. M. A. Lessa, M. R. Kerntopf, C. M. Sousa, R. S. Alves, M. G. R. Queiroz, J. Price, D. B. Heimark, J. Larner, X. Du, M. Brownlee, A. Gow, C. Davis, and M. C. Fonteles
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 218–223. Published online 2005 December 22. doi: 10.1073/pnas.0509779103.
PMCID: PMC1325005
Physiology
From the Cover:
Premature ovarian failure in androgen receptor-deficient mice
Hiroko Shiina, Takahiro Matsumoto, Takashi Sato, Katsuhide Igarashi, Junko Miyamoto, Sayuri Takemasa, Matomo Sakari, Ichiro Takada, Takashi Nakamura, Daniel Metzger, Pierre Chambon, Jun Kanno, Hiroyuki Yoshikawa, and Shigeaki Kato
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 224–229. Published online 2005 December 22. doi: 10.1073/pnas.0506736102.
PMCID: PMC1324980
Plant Biology
Cinnamoyl-CoA reductase, a key enzyme in lignin biosynthesis, is an effector of small GTPase Rac in defense signaling in rice
Tsutomu Kawasaki, Hisako Koita, Tomoyuki Nakatsubo, Kana Hasegawa, Kenichi Wakabayashi, Hiroki Takahashi, Kenji Umemura, Toshiaki Umezawa, and Ko Shimamoto
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 230–235. Published online 2005 December 27. doi: 10.1073/pnas.0509875103.
PMCID: PMC1325009
A gradient of auxin and auxin-dependent transcription precedes tropic growth responses
C. Alex Esmon, Amanda G. Tinsley, Karin Ljung, Goran Sandberg, Leonard B. Hearne, and Emmanuel Liscum
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 236–241. Published online 2005 December 21. doi: 10.1073/pnas.0507127103.
PMCID: PMC1324985
Social Sciences
Anthropology
The questionable contribution of the Neolithic and the Bronze Age to European craniofacial form
C. Loring Brace, Noriko Seguchi, Conrad B. Quintyn, Sherry C. Fox, A. Russell Nelson, Sotiris K. Manolis, and Pan Qifeng
Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 242–247. Published online 2005 December 21. doi: 10.1073/pnas.0509801102.
PMCID: PMC1325007
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