| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 December 6; 102(49): 17537–17538. doi: 10.1073/iti4905102.PMCID: PMC1308939 Commentaries Interfering with interferons: Hepatitis C virus counters innate immunity Eric C. Freundt and Michael J. Lenardo PMCID: PMC1308935 Toward an anandamide transporter Raphael Mechoulam and Dale G. Deutsch PMCID: PMC1308911 Seeing is believing: Structure of the catalytic domain of HIV-1 integrase in complex with human LEDGF/p75 Christina Marchetti Bradley and Robert Craigie PMCID: PMC1308931 Physical Sciences Applied Mathematics Reconstructing the pathways of a cellular system from genome-scale signals by using matrix and tensor computations Orly Alter and Gene H. Golub PMCID: PMC1308929 Applied Physical Sciences Breaking the diffraction barrier in fluorescence microscopy at low light intensities by using reversibly photoswitchable proteins Michael Hofmann, Christian Eggeling, Stefan Jakobs, and Stefan W. Hell PMCID: PMC1308899 Chemistry Cytochrome c conformations resolved by the photon counting histogram: Watching the alkaline transition with single-molecule sensitivity Thomas D. Perroud, Michael P. Bokoch, and Richard N. Zare PMCID: PMC1308922 Root functioning modifies seasonal climate Jung-Eun Lee, Rafael S. Oliveira, Todd E. Dawson, and Inez Fung PMCID: PMC1308914 Removing intensity effects and identifying significant genes for Affymetrix arrays in macrophage migration inhibitory factor-suppressed neuroblastoma cells Jianqing Fan, Yongxiong Chen, Hiu Man Chan, Paul K. H. Tam, and Yi Ren PMCID: PMC1308934 Biological Sciences Agricultural Sciences Global gene expression profiles reveal significant nuclear reprogramming by the blastocyst stage after cloning Sadie L. Smith, Robin E. Everts, X. Cindy Tian, Fuliang Du, Li-Ying Sung, Sandra L. Rodriguez-Zas, Byeong-Seon Jeong, Jean-Paul Renard, Harris A. Lewin, and Xiangzhong Yang PMCID: PMC1308920 Applied Biological Sciences Simple model for tuberculosis in cattle and badgers D. R. Cox, Christl A. Donnelly, F. John Bourne, George Gettinby, John P. McInerney, W. Ivan Morrison, and Rosie Woodroffe PMCID: PMC1292989 Biochemistry INAUGURAL ARTICLE by a Recently Elected Academy Member: Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1 Hyun-Eui Kim, Fenghe Du, Min Fang, and Xiaodong Wang PMCID: PMC1266161 Bioinformatic analyses implicate the collaborating meiotic crossover/chiasma proteins Zip2, Zip3, and Spo22/Zip4 in ubiquitin labeling Jason Perry, Nancy Kleckner, and G. Valentin Börner PMCID: PMC1308910 Crystal structure of Bacillus subtilis anti-TRAP protein, an antagonist of TRAP/RNA interaction Mikhail B. Shevtsov, Yanling Chen, Paul Gollnick, and Alfred A. Antson PMCID: PMC1308913 The molecular structure and catalytic mechanism of a quorum-quenching N-acyl-L-homoserine lactone hydrolase Myung Hee Kim, Won-Chan Choi, Hye Ok Kang, Jong Suk Lee, Beom Sik Kang, Kyung-Jin Kim, Zygmunt S. Derewenda, Tae-Kwang Oh, Choong Hwan Lee, and Jung-Kee Lee PMCID: PMC1295591 Probing conformational changes in T7 RNA polymerase during initiation and termination by using engineered disulfide linkages Kaiyu Ma, Dmitry Temiakov, Michael Anikin, and William T. McAllister PMCID: PMC1308916 Biophysics Identification of oligonucleotide sequences that direct the movement of the Escherichia coli FtsK translocase Oren Levy, Jerod L. Ptacin, Paul J. Pease, Jeff Gore, Michael B. Eisen, Carlos Bustamante, and Nicholas R. Cozzarelli PMCID: PMC1287487 The timing of proton migration in membrane-reconstituted cytochrome c oxidase Lina Salomonsson, Kristina Faxén, Pia Ädelroth, and Peter Brzezinski PMCID: PMC1345723 From the Cover:
Activation-coupled inactivation in the bacterial potassium channel KcsA Lizhi Gao, Xianqiang Mi, Vesa Paajanen, Kun Wang, and Zheng Fan PMCID: PMC1287484 Solution structure of the Set2–Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1 Ming Li, Hemali P. Phatnani, Ziqiang Guan, Harvey Sage, Arno L. Greenleaf, and Pei Zhou PMCID: PMC1308900 Inferring the in vivo looping properties of DNA Leonor Saiz, J. Miguel Rubi, and Jose M. G. Vilar PMCID: PMC1287912 Coupled protein domain motion in Taq polymerase revealed by neutron spin-echo spectroscopy Zimei Bu, Ralf Biehl, Michael Monkenbusch, Dieter Richter, and David J. E. Callaway PMCID: PMC1345721 Structure of a group A streptococcal phage-encoded virulence factor reveals a catalytically active triple-stranded β-helix Nicola L. Smith, Edward J. Taylor, Anna-Marie Lindsay, Simon J. Charnock, Johan P. Turkenburg, Eleanor J. Dodson, Gideon J. Davies, and Gary W. Black PMCID: PMC1308890 Cell Biology Bacterial DNA segregation by dynamic SopA polymers Grace E. Lim, Alan I. Derman, and Joe Pogliano PMCID: PMC1308903 Developmental Biology Dpp signaling and the induction of neoplastic tumors by caspase-inhibited apoptotic cells in Drosophila Ainhoa Pérez-Garijo, Francisco A. Martín, Gary Struhl, and Ginés Morata PMCID: PMC1308921 Evolution Loss of dispensable genes is not adaptive in yeast Piotr Sliwa and Ryszard Korona PMCID: PMC1295593 Genetics Reconstructing the pathways of a cellular system from genome-scale signals by using matrix and tensor computations Orly Alter and Gene H. Golub PMCID: PMC1308929 Profiling condition-specific, genome-wide regulation of mRNA stability in yeast Barrett C. Foat, S. Sean Houshmandi, Wendy M. Olivas, and Harmen J. Bussemaker PMCID: PMC1295595 The relationship between FRQ-protein stability and temperature compensation in the Neurospora circadian clock Peter Ruoff, Jennifer J. Loros, and Jay C. Dunlap PMCID: PMC1308891 Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice Henna Tyynismaa, Katja Peltola Mjosund, Sjoerd Wanrooij, Ilse Lappalainen, Emil Ylikallio, Anu Jalanko, Johannes N. Spelbrink, Anders Paetau, and Anu Suomalainen PMCID: PMC1308896 Studies of the distribution of Escherichia coli cAMP-receptor protein and RNA polymerase along the E. coli chromosome David C. Grainger, Douglas Hurd, Marcus Harrison, Jolyon Holdstock, and Stephen J. W. Busby PMCID: PMC1308901 Mutation in sodium–calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish Adam D. Langenbacher, Yuan Dong, Xiaodong Shu, Jayoung Choi, Debora A. Nicoll, Joshua I. Goldhaber, Kenneth D. Philipson, and Jau-Nian Chen PMCID: PMC1308881 Calcium extrusion is critical for cardiac morphogenesis and rhythm in embryonic zebrafish hearts A. M. Ebert, G. L. Hume, K. S. Warren, N. P. Cook, C. G. Burns, M. A. Mohideen, G. Siegal, D. Yelon, M. C. Fishman, and D. M. Garrity PMCID: PMC1308882 Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA Paul Auerbach, Richard A. O. Bennett, Elisabeth A. Bailey, Hans E. Krokan, and Bruce Demple PMCID: PMC1308887 Immunology From the Cover:
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity Xiao-Dong Li, Lijun Sun, Rashu B. Seth, Gabriel Pineda, and Zhijian J. Chen PMCID: PMC1308909 Allergen-induced peribronchial fibrosis and mucus production mediated by IκB kinase β-dependent genes in airway epithelium David H. Broide, Toby Lawrence, Taylor Doherty, Jae Youn Cho, Marina Miller, Kirsti McElwain, Shauna McElwain, and Michael Karin PMCID: PMC1308936 Endocrine self and gut non-self intersect in the pancreatic lymph nodes Shannon J. Turley, Je-Wook Lee, Nick Dutton-Swain, Diane Mathis, and Christophe Benoist PMCID: PMC1308925 Medical Sciences INAUGURAL ARTICLE by a Recently Elected Academy Member: Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2 Juan I. Young, Eugene P. Hong, John C. Castle, Juan Crespo-Barreto, Aaron B. Bowman, Matthew F. Rose, Dongcheul Kang, Ron Richman, Jason M. Johnson, Susan Berget, and Huda Y. Zoghbi PMCID: PMC1266160 Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves Yasuyuki Amoh, Lingna Li, Raul Campillo, Katsumasa Kawahara, Kensei Katsuoka, Sheldon Penman, and Robert M. Hoffman PMCID: PMC1308908 Counting human somatic cell replications: Methylation mirrors endometrial stem cell divisions Jung Yeon Kim, Simon Tavaré, and Darryl Shibata PMCID: PMC1308885 Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation Michael S. Isakoff, Courtney G. Sansam, Pablo Tamayo, Aravind Subramanian, Julia A. Evans, Christine M. Fillmore, Xi Wang, Jaclyn A. Biegel, Scott L. Pomeroy, Jill P. Mesirov, and Charles W. M. Roberts PMCID: PMC1308926 Removing intensity effects and identifying significant genes for Affymetrix arrays in macrophage migration inhibitory factor-suppressed neuroblastoma cells Jianqing Fan, Yongxiong Chen, Hiu Man Chan, Paul K. H. Tam, and Yi Ren PMCID: PMC1308934 Medical Sciences Rerouting lipoprotein nanoparticles to selected alternate receptors for the targeted delivery of cancer diagnostic and therapeutic agents Gang Zheng, Juan Chen, Hui Li, and Jerry D. Glickson PMCID: PMC1308912 Gene expression profiling differentiates germ cell tumors from other cancers and defines subtype-specific signatures Dejan Juric, Sanja Sale, Robert A. Hromas, Ron Yu, Yan Wang, George E. Duran, Robert Tibshirani, Lawrence H. Einhorn, and Branimir I. Sikic PMCID: PMC1308932 Microbiology Salmonella inhibit T cell proliferation by a direct, contact-dependent immunosuppressive effect Adrianus W. M. van der Velden, Michael K. Copass, and Michael N. Starnbach PMCID: PMC1308886 The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP Daniel D. Isaac, Jerome S. Pinkner, Scott J. Hultgren, and Thomas J. Silhavy PMCID: PMC1308919 Dynamics of hepatitis B virus clearance in chimpanzees John M. Murray, Stefan F. Wieland, Robert H. Purcell, and Francis V. Chisari PMCID: PMC1345724 From the Cover:
Progression of primary pneumonic plague: A mouse model of infection, pathology, and bacterial transcriptional activity Wyndham W. Lathem, Seth D. Crosby, Virginia L. Miller, and William E. Goldman PMCID: PMC1308902 Neuroscience Zfp312 is required for subcortical axonal projections and dendritic morphology of deep-layer pyramidal neurons of the cerebral cortex Jie-Guang Chen, Mladen-Roko Rašin, Kenneth Y. Kwan, and Nenad Šestan PMCID: PMC1308928 Assessing the spatiotemporal evolution of neuronal activation with single-trial event-related potentials and functional MRI Tom Eichele, Karsten Specht, Matthias Moosmann, Marijtje L. A. Jongsma, Rodrigo Quian Quiroga, Helge Nordby, and Kenneth Hugdahl PMCID: PMC1295592 Perfusion functional MRI reveals cerebral blood flow pattern under psychological stress Jiongjiong Wang, Hengyi Rao, Gabriel S. Wetmore, Patricia M. Furlan, Marc Korczykowski, David F. Dinges, and John A. Detre PMCID: PMC1292988 Brain signals for spatial attention predict performance in a motion discrimination task Ayelet Sapir, Giovanni d'Avossa, Mark McAvoy, Gordon L. Shulman, and Maurizio Corbetta PMCID: PMC1308888 Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin Xiang Li, Davina V. Gutierrez, M. Gartz Hanson, Jing Han, Melanie D. Mark, Hillel Chiel, Peter Hegemann, Lynn T. Landmesser, and Stefan Herlitze PMCID: PMC1292990 Gene transfer of human acid sphingomyelinase corrects neuropathology and motor deficits in a mouse model of Niemann-Pick type A disease James C. Dodge, Jennifer Clarke, Antonius Song, Jie Bu, Wendy Yang, Tatyana V. Taksir, Denise Griffiths, Michael A. Zhao, Edward H. Schuchman, Seng H. Cheng, Catherine R. O'Riordan, Lamya S. Shihabuddin, Marco A. Passini, and Gregory R. Stewart PMCID: PMC1308930 Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels Toral S. Surti, Lan Huang, Yuh Nung Jan, Lily Y. Jan, and Edward C. Cooper PMCID: PMC1297712 Altered differentiation of neural stem cells in fragile X syndrome Maija Castrén, Topi Tervonen, Virve Kärkkäinen, Seppo Heinonen, Eero Castrén, Kim Larsson, Cathy E. Bakker, Ben A. Oostra, and Karl Åkerman PMCID: PMC1308923 Retrograde signaling from the brain to the retina modulates the termination of the light response in Drosophila Shantadurga Rajaram, Robert L. Scott, and Howard A. Nash PMCID: PMC1308915 From the Cover:
A mechanism underlying AMPA receptor trafficking during cerebellar long-term potentiation Wataru Kakegawa and Michisuke Yuzaki PMCID: PMC1308917 Pharmacology From the Cover:
Identification of a high-affinity binding site involved in the transport of endocannabinoids S. A. Moore, G. G. Nomikos, A. K. Dickason-Chesterfield, D. A. Schober, J. M. Schaus, B.-P. Ying, Y.-C. Xu, L. Phebus, R. M. A. Simmons, D. Li, S. Iyengar, and C. C. Felder PMCID: PMC1295594 Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types Jacqueline A. Walisser, Edward Glover, Kalyan Pande, Adam L. Liss, and Christopher A. Bradfield PMCID: PMC1308889 Physiology KCNQ1-dependent transport in renal and gastrointestinal epithelia Volker Vallon, Florian Grahammer, Harald Volkl, Ciprian D. Sandu, Kerstin Richter, Rexhepi Rexhepaj, Uwe Gerlach, Qi Rong, Karl Pfeifer, and Florian Lang PMCID: PMC1308898 A cysteine-rich motif confers hypoxia sensitivity to mammalian large conductance voltage- and Ca-activated K (BK) channel α-subunits Claire E. McCartney, Heather McClafferty, Jean-Marc Huibant, Edward G. Rowan, Michael J. Shipston, and Iain C. M. Rowe PMCID: PMC1308893 Plant Biology Root functioning modifies seasonal climate Jung-Eun Lee, Rafael S. Oliveira, Todd E. Dawson, and Inez Fung PMCID: PMC1308914 Social Sciences Psychology Frequency effects in compound production Heidrun Bien, Willem J. M. Levelt, and R. Harald Baayen PMCID: PMC1287486 Corrections Proc Natl Acad Sci U S A. 2005 December 6; 102(49): 17882. doi: 10.1073/pnas.0509460102.PMCID: PMC1308937 Corrects: Yoshihiro Nakatani, et al. From the Cover:
p600, a unique protein required for membrane morphogenesis and cell survival. Proc Natl Acad Sci U S A. 2005 October 18; 102(42): 15093–15098. Proc Natl Acad Sci U S A. 2005 December 6; 102(49): 17882. doi: 10.1073/pnas.0509474102.PMCID: PMC1308938 Corrects: Lance D. Miller, et al. From the Cover:
An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival. Proc Natl Acad Sci U S A. 2005 September 20; 102(38): 13550–13555. |
