| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7777–7778. doi: 10.1073/iti2205102.PMCID: PMC1142400 Commentaries Autophagy and intracellular surveillance: Modulating MHC class II antigen presentation with stress Victoria L. Crotzer and Janice S. Blum Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7779–7780. Published online 2005 May 23. doi: 10.1073/pnas.0503088102.PMCID: PMC1142394 Molecular engineering human hepatocytes into pancreatic beta cells for diabetes therapy Irene Cozar-Castellano and Andrew F. Stewart Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7781–7782. Published online 2005 May 23. doi: 10.1073/pnas.0503261102.PMCID: PMC1142398 PNAS Classic Article Perspective: The sources of Schwinger's Green's functions Silvan S. Schweber Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7783–7788. doi: 10.1073/pnas.0405167101.PMCID: PMC1142349 Perspective Nobel Lecture: The dilemma of attribution H. David Politzer Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7789–7793. Published online 2005 May 23. doi: 10.1073/pnas.0501644102.PMCID: PMC1142376 Physical Sciences Applied Mathematics From the Cover: The worldwide air transportation network: Anomalous centrality, community structure, and cities' global roles R. Guimerà, S. Mossa, A. Turtschi, and L. A. N. Amaral Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7794–7799. Published online 2005 May 23. doi: 10.1073/pnas.0407994102.PMCID: PMC1142352 Applied Physical Sciences Optical routing and sensing with nanowire assemblies Donald J. Sirbuly, Matt Law, Peter Pauzauskie, Haoquan Yan, Alex V. Maslov, Kelly Knutsen, Cun-Zheng Ning, Richard J. Saykally, and Peidong Yang Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7800–7805. Published online 2005 May 23. doi: 10.1073/pnas.0408641102.PMCID: PMC1142354 Physics Gain-swept superradiance applied to the stand-off detection of trace impurities in the atmosphere V. Kocharovsky, S. Cameron, K. Lehmann, R. Lucht, R. Miles, Y. Rostovtsev, W. Warren, G. R. Welch, and M. O. Scully Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7806–7811. Published online 2005 May 23. doi: 10.1073/pnas.0500534102.PMCID: PMC1142365 Statistics Subtree power analysis and species selection for comparative genomics Jon D. McAuliffe, Michael I. Jordan, and Lior Pachter Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7900–7905. Published online 2005 May 23. doi: 10.1073/pnas.0502790102.PMCID: PMC1142384 Biological Sciences Agricultural Sciences An alternative strategy for sustainable pest resistance in genetically enhanced crops Luke Mehlo, Daphrose Gahakwa, Pham Trung Nghia, Nguyen Thi Loc, Teresa Capell, John A. Gatehouse, Angharad M. R. Gatehouse, and Paul Christou Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7812–7816. Published online 2005 May 20. doi: 10.1073/pnas.0502871102.PMCID: PMC1142385 Applied Biological Sciences Differential adhesion of amino acids to inorganic surfaces R. L. Willett, K. W. Baldwin, K. W. West, and L. N. Pfeiffer Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7817–7822. doi: 10.1073/pnas.0408565102.PMCID: PMC1142353 Biochemistry From the Cover: DksA potentiates direct activation of amino acid promoters by ppGpp Brian J. Paul, Melanie B. Berkmen, and Richard L. Gourse Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7823–7828. Published online 2005 May 17. doi: 10.1073/pnas.0501170102.PMCID: PMC1142371 Biophysics A quantum mechanical polarizable force field for biomolecular interactions A. G. Donchev, V. D. Ozrin, M. V. Subbotin, O. V. Tarasov, and V. I. Tarasov Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7829–7834. Published online 2005 May 23. doi: 10.1073/pnas.0502962102.PMCID: PMC1142387 Theoretical model of prion propagation: A misfolded protein induces misfolding Edyta Małolepsza, Michał Boniecki, Andrzej Kolinski, and Lucjan Piela Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7835–7840. Published online 2005 May 23. doi: 10.1073/pnas.0409389102.PMCID: PMC1142357 Topological units of environmental signal processing in the transcriptional regulatory network of Escherichia coli G. Balázsi, A.-L. Barabási, and Z. N. Oltvai Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7841–7846. Published online 2005 May 20. doi: 10.1073/pnas.0500365102.PMCID: PMC1142363 Stress release drives symmetry breaking for actin-based movement Jasper van der Gucht, Ewa Paluch, Julie Plastino, and Cécile Sykes Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7847–7852. Published online 2005 May 23. doi: 10.1073/pnas.0502121102.PMCID: PMC1142378 Cell Biology A vital role of tubulin-tyrosine-ligase for neuronal organization Christian Erck, Leticia Peris, Annie Andrieux, Claire Meissirel, Achim D. Gruber, Muriel Vernet, Annie Schweitzer, Yasmina Saoudi, Hervé Pointu, Christophe Bosc, Paul A. Salin, Didier Job, and Juergen Wehland Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7853–7858. Published online 2005 May 17. doi: 10.1073/pnas.0409626102.PMCID: PMC1129054 Targeted expression of the inositol 1,4,5-triphosphate receptor (IP3R) ligand-binding domain releases Ca2+ via endogenous IP3R channels Péter Várnai, András Balla, László Hunyady, and Tamas Balla Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7859–7864. Published online 2005 May 23. doi: 10.1073/pnas.0407535102.PMCID: PMC1142351 Developmental Biology Epigenetic programming in the preimplantation rat embryo is disrupted by chronic paternal cyclophosphamide exposure Tara S. Barton, Bernard Robaire, and Barbara F. Hales Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7865–7870. Published online 2005 May 23. doi: 10.1073/pnas.0501200102.PMCID: PMC1138259 Ecology Source pool geometry and the assembly of continental avifaunas Gary R. Graves and Carsten Rahbek Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7871–7876. Published online 2005 May 23. doi: 10.1073/pnas.0500424102.PMCID: PMC1142364 Evolution From the Cover: Deep history impacts present-day ecology and biodiversity Laurie J. Vitt and Eric R. Pianka Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7877–7881. Published online 2005 May 2. doi: 10.1073/pnas.0501104102.PMCID: PMC1142370 Simultaneous inference of selection and population growth from patterns of variation in the human genome Scott H. Williamson, Ryan Hernandez, Adi Fledel-Alon, Lan Zhu, Rasmus Nielsen, and Carlos D. Bustamante Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7882–7887. Published online 2005 May 19. doi: 10.1073/pnas.0502300102.PMCID: PMC1142382 Genetics Establishing genetic transformation for comparative developmental studies in the crustacean Parhyale hawaiensis Anastasios Pavlopoulos and Michalis Averof Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7888–7893. Published online 2005 May 23. doi: 10.1073/pnas.0501101102.PMCID: PMC1142369 A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) mice Chantal M. Longo-Guess, Leona H. Gagnon, Susan A. Cook, Jian Wu, Qing Y. Zheng, and Kenneth R. Johnson Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7894–7899. Published online 2005 May 19. doi: 10.1073/pnas.0500760102.PMCID: PMC1142366 Subtree power analysis and species selection for comparative genomics Jon D. McAuliffe, Michael I. Jordan, and Lior Pachter Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7900–7905. Published online 2005 May 23. doi: 10.1073/pnas.0502790102.PMCID: PMC1142384 No association between microsomal triglyceride transfer protein (MTP) haplotype and longevity in humans Almut Nebel, Peter J. P. Croucher, Rieke Stiegeler, Susanna Nikolaus, Michael Krawczak, and Stefan Schreiber Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7906–7909. Published online 2005 May 23. doi: 10.1073/pnas.0408670102.PMCID: PMC1142355 Immunology Involvement of clathrin and AP-2 in the trafficking of MHC class II molecules to antigen-processing compartments Peter J. McCormick, José A. Martina, and Juan S. Bonifacino Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7910–7915. Published online 2005 May 23. doi: 10.1073/pnas.0502206102.PMCID: PMC1138261 Characterization of subsets of CD4+ memory T cells reveals early branched pathways of T cell differentiation in humans Kaimei Song, Ronald L. Rabin, Brenna J. Hill, Stephen C. De Rosa, Stephen P. Perfetto, Hongwei H. Zhang, John F. Foley, Jeffrey S. Reiner, Jie Liu, Joseph J. Mattapallil, Daniel C. Douek, Mario Roederer, and Joshua M. Farber Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7916–7921. Published online 2005 May 19. doi: 10.1073/pnas.0409720102.PMCID: PMC1131816 From the Cover: Autophagy promotes MHC class II presentation of peptides from intracellular source proteins Jörn Dengjel, Oliver Schoor, Rainer Fischer, Michael Reich, Marianne Kraus, Margret Müller, Katharina Kreymborg, Florian Altenberend, Jens Brandenburg, Hubert Kalbacher, Roland Brock, Christoph Driessen, Hans-Georg Rammensee, and Stefan Stevanovic Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7922–7927. Published online 2005 May 13. doi: 10.1073/pnas.0501190102.PMCID: PMC1142372 Activated antigen-presenting cells select and present chemically modified peptides recognized by unique CD4 T cells Jeremy Herzog, Yoichi Maekawa, Thomas P. Cirrito, Beverly S. Illian, and Emil R. Unanue Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7928–7933. Published online 2005 May 18. doi: 10.1073/pnas.0502255102.PMCID: PMC1130168 A critical role of T cell antigen receptor-transduced MHC class I-restricted helper T cells in tumor protection Emma C. Morris, Aristotle Tsallios, Gavin M. Bendle, Shao-an Xue, and Hans J. Stauss Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7934–7939. Published online 2005 May 20. doi: 10.1073/pnas.0500357102.PMCID: PMC1142362 Identification of cancer/testis-antigen genes by massively parallel signature sequencing Yao-Tseng Chen, Matthew J. Scanlan, Charis A. Venditti, Ramon Chua, Gregory Theiler, Brian J. Stevenson, Christian Iseli, Ali O. Gure, Tom Vasicek, Robert L. Strausberg, C. Victor Jongeneel, Lloyd J. Old, and Andrew J. G. Simpson Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7940–7945. Published online 2005 May 19. doi: 10.1073/pnas.0502583102.PMCID: PMC1142383 Medical Sciences Cell membrane-specific epitopes on CD30: Potentially superior targets for immunotherapy Satoshi Nagata, Tomoko Ise, Masanori Onda, Kazuyasu Nakamura, Mitchell Ho, Andrew Raubitschek, and Ira H. Pastan Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7946–7951. Published online 2005 May 19. doi: 10.1073/pnas.0502975102.PMCID: PMC1142388 Microbes on the human vaginal epithelium Richard W. Hyman, Marilyn Fukushima, Lisa Diamond, Jochen Kumm, Linda C. Giudice, and Ronald W. Davis Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7952–7957. Published online 2005 May 23. doi: 10.1073/pnas.0503236102.PMCID: PMC1142396 Anthrax lethal factor inhibition W. L. Shoop, Y. Xiong, J. Wiltsie, A. Woods, J. Guo, J. V. Pivnichny, T. Felcetto, B. F. Michael, A. Bansal, R. T. Cummings, B. R. Cunningham, A. M. Friedlander, C. M. Douglas, S. B. Patel, D. Wisniewski, G. Scapin, S. P. Salowe, D. M. Zaller, K. T. Chapman, E. M. Scolnick, D. M. Schmatz, K. Bartizal, M. MacCoss, and J. D. Hermes Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7958–7963. Published online 2005 May 23. doi: 10.1073/pnas.0502159102.PMCID: PMC1138260 From the Cover: Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells Tamar Sapir, Keren Shternhall, Irit Meivar-Levy, Tamar Blumenfeld, Hamutal Cohen, Ehud Skutelsky, Smadar Eventov-Friedman, Iris Barshack, Iris Goldberg, Sarah Pri-Chen, Lya Ben-Dor, Sylvie Polak-Charcon, Avraham Karasik, Ilan Shimon, Eytan Mor, and Sarah Ferber Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7964–7969. Published online 2005 May 17. doi: 10.1073/pnas.0405277102.PMCID: PMC1142350 MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes Mark D. Erion, Paul D. van Poelje, Qun Dang, Srinivas Rao Kasibhatla, Scott C. Potter, M. Rami Reddy, K. Raja Reddy, Tao Jiang, and William N. Lipscomb Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7970–7975. Published online 2005 May 23. doi: 10.1073/pnas.0502983102.PMCID: PMC1138262 Synergistic effects of light-emitting probes and peptides for targeting and monitoring integrin expression Samuel Achilefu, Sharon Bloch, Mary A. Markiewicz, Tuoxiu Zhong, Yunpeng Ye, Richard B. Dorshow, Britton Chance, and Kexian Liang Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7976–7981. Published online 2005 May 23. doi: 10.1073/pnas.0503500102.PMCID: PMC1142399 Microbiology The antiretroviral activity of APOBEC3 is inhibited by the foamy virus accessory Bet protein Martin Löchelt, Fabian Romen, Patrizia Bastone, Heide Muckenfuss, Nadine Kirchner, Yong-Boum Kim, Uwe Truyen, Uwe Rösler, Marion Battenberg, Ali Saib, Egbert Flory, Klaus Cichutek, and Carsten Münk Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7982–7987. Published online 2005 May 23. doi: 10.1073/pnas.0501445102.PMCID: PMC1142374 Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry Heike Hofmann, Krzysztof Pyrc, Lia van der Hoek, Martina Geier, Ben Berkhout, and Stefan Pöhlmann Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7988–7993. Published online 2005 May 16. doi: 10.1073/pnas.0409465102.PMCID: PMC1142358 Emergence of unique primate T-lymphotropic viruses among central African bushmeat hunters Nathan D. Wolfe, Walid Heneine, Jean K. Carr, Albert D. Garcia, Vedapuri Shanmugam, Ubald Tamoufe, Judith N. Torimiro, A. Tassy Prosser, Matthew LeBreton, Eitel Mpoudi-Ngole, Francine E. McCutchan, Deborah L. Birx, Thomas M. Folks, Donald S. Burke, and William M. Switzer Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7994–7999. Published online 2005 May 23. doi: 10.1073/pnas.0501734102.PMCID: PMC1142377 Resting naïve CD4+ T cells are massively infected and eliminated by X4-tropic simian–human immunodeficiency viruses in macaques Yoshiaki Nishimura, Charles R. Brown, Joseph J. Mattapallil, Tatsuhiko Igarashi, Alicia Buckler-White, Bernard A. P. Lafont, Vanessa M. Hirsch, Mario Roederer, and Malcolm A. Martin Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 8000–8005. Published online 2005 May 23. doi: 10.1073/pnas.0503233102.PMCID: PMC1142395 ExsE, a secreted regulator of type III secretion genes in Pseudomonas aeruginosa Arne Rietsch, Isabelle Vallet-Gely, Simon L. Dove, and John J. Mekalanos Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 8006–8011. Published online 2005 May 23. doi: 10.1073/pnas.0503005102.PMCID: PMC1142391 Rapid identification and strain-typing of respiratory pathogens for epidemic surveillance David J. Ecker, Rangarajan Sampath, Lawrence B. Blyn, Mark W. Eshoo, Cristina Ivy, Joseph A. Ecker, Brian Libby, Vivek Samant, Kristin A. Sannes-Lowery, Rachael E. Melton, Kevin Russell, Nikki Freed, Chris Barrozo, Jianguo Wu, Karl Rudnick, Anjali Desai, Emily Moradi, Duane J. Knize, David W. Robbins, James C. Hannis, Patina M. Harrell, Christian Massire, Thomas A. Hall, Yun Jiang, Raymond Ranken, Jared J. Drader, Neill White, John A. McNeil, Stanley T. Crooke, and Steven A. Hofstadler Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 8012–8017. doi: 10.1073/pnas.0409920102.PMCID: PMC1138257 Conserved modular design of an oxygen sensory/signaling network with species-specific output Sean Crosson, Patrick T. McGrath, Craig Stephens, Harley H. McAdams, and Lucy Shapiro Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 8018–8023. Published online 2005 May 23. doi: 10.1073/pnas.0503022102.PMCID: PMC1142393 Neuroscience Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease Alexander J. Whitworth, Dorothy A. Theodore, Jessica C. Greene, Helen Beneš, Paul D. Wes, and Leo J. Pallanck Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 8024–8029. Published online 2005 May 23. doi: 10.1073/pnas.0501078102.PMCID: PMC1142368 Carbonic anhydrase XIV is enriched in specific membrane domains of retinal pigment epithelium, Müller cells, and astrocytes Erlend A. Nagelhus, Thomas M. Mathiisen, Allen C. Bateman, Finn-M. Haug, Ole P. Ottersen, Jeffrey H. Grubb, Abdul Waheed, and William S. Sly Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 8030–8035. Published online 2005 May 18. doi: 10.1073/pnas.0503021102.PMCID: PMC1142392 Replaceable neurons and neurodegenerative disease share depressed UCHL1 levels Anthony J. Lombardino, Xiao-Ching Li, Moritz Hertel, and Fernando Nottebohm Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 8036–8041. Published online 2005 May 23. doi: 10.1073/pnas.0503239102.PMCID: PMC1142397 Pharmacology P2Y1 receptor signaling is controlled by interaction with the PDZ scaffold NHERF-2 Sami R. Fam, Maryse Paquet, Amanda M. Castleberry, Heide Oller, C. Justin Lee, Stephen F. Traynelis, Yoland Smith, C. Chris Yun, and Randy A. Hall Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 8042–8047. Published online 2005 May 18. doi: 10.1073/pnas.0408818102.PMCID: PMC1142356 Physiology Epidermal growth factor prevents prepartum luteolysis in the rat M. L. Ribeiro, J. Aisemberg, S. Billi, M. G. Farina, R. Meiss, S. McCann, V. Rettori, M. Villalón, and A. M. Franchi Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 8048–8053. Published online 2005 May 23. doi: 10.1073/pnas.0502899102.PMCID: PMC1142386 Plant Biology A central role for S-nitrosothiols in plant disease resistance Angela Feechan, Eunjung Kwon, Byung-Wook Yun, Yiqin Wang, Jacqueline A. Pallas, and Gary J. Loake Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 8054–8059. Published online 2005 May 23. doi: 10.1073/pnas.0501456102.PMCID: PMC1142375 Loblolly pine abietadienol/abietadienal oxidase PtAO (CYP720B1) is a multifunctional, multisubstrate cytochrome P450 monooxygenase Dae-Kyun Ro, Gen-Ichiro Arimura, Stephen Y. W. Lau, Edward Piers, and Jörg Bohlmann Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 8060–8065. Published online 2005 May 23. doi: 10.1073/pnas.0500825102.PMCID: PMC1138258 Comparative transcriptomics of rice reveals an ancient pattern of response to microbial colonization Sonia Güimil, Hur-Song Chang, Tong Zhu, Ane Sesma, Anne Osbourn, Christophe Roux, Vassilios Ioannidis, Edward J. Oakeley, Mylène Docquier, Patrick Descombes, Steven P. Briggs, and Uta Paszkowski Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 8066–8070. Published online 2005 May 19. doi: 10.1073/pnas.0502999102.PMCID: PMC1142390 |