| | This journal provides immediate access to some articles. Commentaries A molecular biology approach to tuberculosis Michel Tibayrenc PMCID: PMC387313 Stromal fibroblasts influence human mammary epithelial cell morphogenesis Daniel Medina PMCID: PMC387314 Biography INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of Enrico Coen Christen Brownlee PMCID: PMC387315 Physical Sciences Applied Mathematics A multiscale model for tropical intraseasonal oscillations Andrew J. Majda and Joseph A. Biello PMCID: PMC387317 Physics From the Cover:
On the sharpness of the interfaces in metallic multilayers E. Holmström, L. Nordström, L. Bergqvist, B. Skubic, B. Hjörvarsson, I. A. Abrikosov, P. Svedlindh, and O. Eriksson PMCID: PMC387318 Biological Sciences Anthropology Distinguishing human ethnic groups by means of sequences from Helicobacter pylori: Lessons from Ladakh Thierry Wirth, Xiaoyan Wang, Bodo Linz, Richard P. Novick, J. Koji Lum, Martin Blaser, Giovanna Morelli, Daniel Falush, and Mark Achtman PMCID: PMC387319 Biochemistry Metabolite-initiated protein misfolding may trigger Alzheimer's disease Qinghai Zhang, Evan T. Powers, Jorge Nieva, Mary E. Huff, Maria A. Dendle, Jan Bieschke, Charles G. Glabe, Albert Eschenmoser, Paul Wentworth, Jr., Richard A. Lerner, and Jeffery W. Kelly PMCID: PMC387320 Structural basis of androgen receptor binding to selective androgen response elements Paul L. Shaffer, Arif Jivan, D. Eric Dollins, Frank Claessens, and Daniel T. Gewirth PMCID: PMC387321 Total chemical synthesis and electrophysiological characterization of mechanosensitive channels from Escherichia coli and Mycobacterium tuberculosis Daniel Clayton, George Shapovalov, Joshua A. Maurer, Dennis A. Dougherty, Henry A. Lester, and Gerd G. Kochendoerfer PMCID: PMC387322 Apoptosis or growth arrest: Modulation of tumor suppressor p53's specificity by bacterial redox protein azurin Tohru Yamada, Yoshinori Hiraoka, Masateru Ikehata, Kazuhide Kimbara, Benjamin S. Avner, Tapas K. Das Gupta, and Ananda M. Chakrabarty PMCID: PMC387323 Biophysics Promoter unwinding and promoter clearance by RNA polymerase: Detection by single-molecule DNA nanomanipulation Andrey Revyakin, Richard H. Ebright, and Terence R. Strick PMCID: PMC387324 The yeast cell-cycle network is robustly designed Fangting Li, Tao Long, Ying Lu, Qi Ouyang, and Chao Tang PMCID: PMC387325 The unique insert in myosin VI is a structural calcium–calmodulin binding site Amel Bahloul, Guillaume Chevreux, Amber L. Wells, Davy Martin, Jocelyn Nolt, Zhaohui Yang, Li-Qiong Chen, Noëlle Potier, Alain Van Dorsselaer, Steve Rosenfeld, Anne Houdusse, and H. Lee Sweeney PMCID: PMC387326 Biomolecular cryocrystallography: Structural changes during flash-cooling Bertil Halle PMCID: PMC387327 Protein kinetics: Structures of intermediates and reaction mechanism from time-resolved x-ray data Marius Schmidt, Reinhard Pahl, Vukica Srajer, Spencer Anderson, Zhong Ren, Hyotcherl Ihee, Sudarshan Rajagopal, and Keith Moffat PMCID: PMC387328 Beyond the diffusion limit: Water flow through the empty bacterial potassium channel Sapar M. Saparov and Peter Pohl PMCID: PMC387329 Cell Biology The yeast cell-cycle network is robustly designed Fangting Li, Tao Long, Ying Lu, Qi Ouyang, and Chao Tang PMCID: PMC387325 Dynamics of coilin in Cajal bodies of the Xenopus germinal vesicle Svetlana Deryusheva and Joseph G. Gall PMCID: PMC387330 Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation Masayoshi Fukasawa, Oleg Varlamov, William S. Eng, Thomas H. Söllner, and James E. Rothman PMCID: PMC387331 Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor Akrit Sodhi, Silvia Montaner, Vyomesh Patel, José Javier Gómez-Román, Yi Li, Edward A. Sausville, Earl T. Sawai, and J. Silvio Gutkind PMCID: PMC387332 Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor Damien Derouet, François Rousseau, Fabienne Alfonsi, Josy Froger, Jacques Hermann, Fabien Barbier, David Perret, Caroline Diveu, Catherine Guillet, Laurence Preisser, Agnès Dumont, Maud Barbado, Alain Morel, Odile deLapeyrière, Hugues Gascan, and Sylvie Chevalier PMCID: PMC387333 QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis Shouwen Wang, Xingbin Ai, Stephen D. Freeman, Mary E. Pownall, Qun Lu, Daniel S. Kessler, and Charles P. Emerson, Jr. PMCID: PMC387334 Developmental Biology INAUGURAL ARTICLE by a Recently Elected Academy Member: The genetics of geometry Enrico Coen, Anne-Gaëlle Rolland-Lagan, Mark Matthews, J. Andrew Bangham, and Przemyslaw Prusinkiewicz PMCID: PMC387316 Controlling transgene expression to study Xenopus laevis metamorphosis Biswajit Das and Donald D. Brown PMCID: PMC387335 From the Cover:
Reciprocal relationships between Fgf8 and neural crest cells in facial and forebrain development Sophie Creuzet, Bernadette Schuler, Gérard Couly, and Nicole M. Le Douarin PMCID: PMC387336 HetR homodimer is a DNA-binding protein required for heterocyst differentiation, and the DNA-binding activity is inhibited by PatS Xu Huang, Yuqing Dong, and Jindong Zhao PMCID: PMC387337 Ecology Tigers and their prey: Predicting carnivore densities from prey abundance K. Ullas Karanth, James D. Nichols, N. Samba Kumar, William A. Link, and James E. Hines PMCID: PMC387338 Successful herbivore attack due to metabolic diversion of a plant chemical defense Ute Wittstock, Niels Agerbirk, Einar J. Stauber, Carl Erik Olsen, Michael Hippler, Thomas Mitchell-Olds, Jonathan Gershenzon, and Heiko Vogel PMCID: PMC387339 Evolution From the Cover:
Functional and evolutionary genomics of Mycobacterium tuberculosis: Insights from genomic deletions in 100 strains Anthony G. Tsolaki, Aaron E. Hirsh, Kathryn DeRiemer, Jose Antonio Enciso, Melissa Z. Wong, Margaret Hannan, Yves-Olivier L. Goguet de la Salmoniere, Kumiko Aman, Midori Kato-Maeda, and Peter M. Small PMCID: PMC387340 From the Cover:
Stable association between strains of Mycobacterium tuberculosis and their human host populations Aaron E. Hirsh, Anthony G. Tsolaki, Kathryn DeRiemer, Marcus W. Feldman, and Peter M. Small PMCID: PMC387341 From the Cover:
Differential expression patterns of the hox gene are associated with differential growth of insect hind legs Najmus S. Mahfooz, Hua Li, and Aleksandar Popadić PMCID: PMC387342 Overcoming an evolutionary conflict: Removal of a reproductive organ greatly increases locomotor performance Margarita Ramos, Duncan J. Irschick, and Terry E. Christenson PMCID: PMC387343 Signatures of selection among sex-determining alleles of the honey bee Martin Hasselmann and Martin Beye PMCID: PMC387344 Long-term reinfection of the human genome by endogenous retroviruses Robert Belshaw, Vini Pereira, Aris Katzourakis, Gillian Talbot, Jan Pačes, Austin Burt, and Michael Tristem PMCID: PMC387345 Nuclear protein-coding genes support lungfish and not the coelacanth as the closest living relatives of land vertebrates Henner Brinkmann, Byrappa Venkatesh, Sydney Brenner, and Axel Meyer PMCID: PMC387346 Genetics RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies Vladimir I. Kashuba, Jingfeng Li, Fuli Wang, Vera N. Senchenko, Alexey Protopopov, Alena Malyukova, Alexey S. Kutsenko, Elena Kadyrova, Veronika I. Zabarovska, Olga V. Muravenko, Alexander V. Zelenin, Lev L. Kisselev, Igor Kuzmin, John D. Minna, Gösta Winberg, Ingemar Ernberg, Eleonora Braga, Michael I. Lerman, George Klein, and Eugene R. Zabarovsky PMCID: PMC387347 Generation of single and double knockdowns in polarized epithelial cells by retrovirus-mediated RNA interference Sebastian Schuck, Aki Manninen, Masanori Honsho, Joachim Füllekrug, and Kai Simons PMCID: PMC387348 Protection against zinc toxicity by metallothionein and zinc transporter 1 Richard D. Palmiter PMCID: PMC387349 Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia L. H. Castilla, P. Perrat, N. J. Martinez, S. F. Landrette, R. Keys, S. Oikemus, J. Flanegan, S. Heilman, L. Garrett, A. Dutra, S. Anderson, G. A. Pihan, L. Wolff, and P. P. Liu PMCID: PMC387350 A global suppressor motif for p53 cancer mutants Timothy E. Baroni, Ting Wang, Hua Qian, Lawrence R. Dearth, Lan N. Truong, Jue Zeng, Alec E. Denes, Stephanie W. Chen, and Rainer K. Brachmann PMCID: PMC387351 Immunology Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals Yina H. Huang, Dongling Li, Astar Winoto, and Ellen A. Robey PMCID: PMC387352 Conserved T cell receptor usage in primary and recall responses to an immunodominant influenza virus nucleoprotein epitope Katherine Kedzierska, Stephen J. Turner, and Peter C. Doherty PMCID: PMC387353 Medical Sciences Effects of acute and chronic administration of β-adrenoceptor ligands on airway function in a murine model of asthma Zsuzsanna Callaerts-Vegh, Kenda L. J. Evans, Noornabi Dudekula, Donald Cuba, Brian J. Knoll, Patrick F. K. Callaerts, Heather Giles, Felix R. Shardonofsky, and Richard A. Bond PMCID: PMC387354 The basal layer in human squamous tumors harbors more UVA than UVB fingerprint mutations: A role for UVA in human skin carcinogenesis Nita S. Agar, Gary M. Halliday, Ross StC. Barnetson, Honnavara N. Ananthaswamy, Mark Wheeler, and Alexandra M. Jones PMCID: PMC387355 Simvastatin induces apoptosis of Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines and delays development of EBV lymphomas Harutaka Katano, Lesley Pesnicak, and Jeffrey I. Cohen PMCID: PMC387356 From the Cover:
Reconstruction of functionally normal and malignant human breast tissues in mice Charlotte Kuperwasser, Tony Chavarria, Min Wu, Greg Magrane, Joe W. Gray, Loucinda Carey, Andrea Richardson, and Robert A. Weinberg PMCID: PMC387357 Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-κB inhibition Maria H. Lind, Björn Rozell, Robert P. A. Wallin, Max van Hogerlinden, Hans-Gustaf Ljunggren, Rune Toftgård, and Inderpreet Sur PMCID: PMC387358 Surfactant protein secreted by the maturing mouse fetal lung acts as a hormone that signals the initiation of parturition Jennifer C. Condon, Pancharatnam Jeyasuria, Julie M. Faust, and Carole R. Mendelson PMCID: PMC387359 Germ-line expression of an oncogenic erbB2 allele confers resistance to erbB2-induced mammary tumorigenesis Eran R. Andrechek, William R. Hardy, Michael A. Laing, and William J. Muller PMCID: PMC387360 Melanoma cells transfected to express CD83 induce antitumor immunity that can be increased by also engaging CD137 Shilin Yang, Yi Yang, John Raycraft, Hongtao Zhang, Sandra Kanan, Yajun Guo, Ze'ev Ronai, Ingegerd Hellstrom, and Karl Erik Hellstrom PMCID: PMC387361 Effect of long-term treatment with low doses of the LHRH antagonist Cetrorelix on pituitary receptors for LHRH and gonadal axis in male and female rats Judit E. Horvath, Gabor L. Toller, Andrew V. Schally, Ana-Maria Bajo, and Kate Groot PMCID: PMC387362 The mutator pathway is a feature of immunodeficiency-related lymphomas Alex Duval, Martine Raphael, Caroline Brennetot, Helene Poirel, Olivier Buhard, Alban Aubry, Antoine Martin, Amor Krimi, Veronique Leblond, Jean Gabarre, Frederic Davi, Frederic Charlotte, Francoise Berger, Gianluca Gaidano, Daniela Capello, Danielle Canioni, Dominique Bordessoule, Jean Feuillard, Philippe Gaulard, Marie Helene Delfau, Sophie Ferlicot, Virginie Eclache, Sophie Prevot, Catherine Guettier, Pascale Cornillet Lefevre, Francoise Adotti, and Richard Hamelin PMCID: PMC387363 Models of granulocyte DNA structure are highly predictive of myelodysplastic syndrome Donald C. Malins, Katie M. Anderson, Nayak L. Polissar, Gary K. Ostrander, Edward T. Knobbe, Virginia M. Green, Naomi K. Gilman, and Jerry L. Spivak PMCID: PMC387364 Microbiology Similarity to peroxisomal-membrane protein family reveals that Sinorhizobium and Brucella BacA affect lipid-A fatty acids Gail P. Ferguson, Anup Datta, John Baumgartner, R. Martin Roop, II, Russ W. Carlson, and Graham C. Walker PMCID: PMC387365 Both chemotaxis and net motility greatly influence the infectivity of Vibrio cholerae Susan M. Butler and Andrew Camilli PMCID: PMC387366 The spatial orientation of Helicobacter pylori in the gastric mucus Sören Schreiber, Manuela Konradt, Claudia Groll, Peter Scheid, Guido Hanauer, Hans-Otto Werling, Christine Josenhans, and Sebastian Suerbaum PMCID: PMC387367 Complex molecular architecture of beet yellows virus particles Valera V. Peremyslov, Igor A. Andreev, Alexey I. Prokhnevsky, George H. Duncan, Michael E. Taliansky, and Valerian V. Dolja PMCID: PMC387368 Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins Zhihai Si, Navid Madani, Jason M. Cox, Jason J. Chruma, Jeffrey C. Klein, Arne Schön, Ngoc Phan, Liping Wang, Alyssa C. Biorn, Simon Cocklin, Irwin Chaiken, Ernesto Freire, Amos B. Smith, III, and Joseph G. Sodroski PMCID: PMC387369 mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia Thomas R. Kozel, William J. Murphy, Suzanne Brandt, Bruce R. Blazar, Julie A. Lovchik, Peter Thorkildson, Ann Percival, and C. Rick Lyons PMCID: PMC387370 Tyrosol is a quorum-sensing molecule in Candida albicans Hao Chen, Masaki Fujita, Qinghua Feng, Jon Clardy, and Gerald R. Fink PMCID: PMC387371 Neuroscience Infraslow oscillations modulate excitability and interictal epileptic activity in the human cortex during sleep S. Vanhatalo, J. M. Palva, M. D. Holmes, J. W. Miller, J. Voipio, and K. Kaila PMCID: PMC387372 A highly conserved candidate chemoreceptor expressed in both olfactory and gustatory tissues in the malaria vector Anopheles gambiae R. Jason Pitts, A. Nicole Fox, and Laurence J. Zwiebel PMCID: PMC387373 Visual memory task for rats reveals an essential role for hippocampus and perirhinal cortex G. T. Prusky, R. M. Douglas, L. Nelson, A. Shabanpoor, and R. J. Sutherland PMCID: PMC387374 Gene discovery in genetically labeled single dopaminergic neurons of the retina Stefano Gustincich, Massimo Contini, Manuela Gariboldi, Michelino Puopolo, Koji Kadota, Hidemasa Bono, Julianna LeMieux, Pamela Walsh, Piero Carninci, Yoshihide Hayashizaki, Yasushi Okazaki, and Elio Raviola PMCID: PMC387375 Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration Katerina Akassoglou, Brian Malester, Jixiang Xu, Lino Tessarollo, Jack Rosenbluth, and Moses V. Chao PMCID: PMC387376 Intracortical mechanism of stimulus-timing-dependent plasticity in visual cortical orientation tuning Haishan Yao, Yaosong Shen, and Yang Dan PMCID: PMC387377 Defective transcription factor activation for proinflammatory gene expression in poly(ADP-ribose) polymerase 1-deficient glia Hyo Chol Ha PMCID: PMC387378 D2 receptor regulation of synaptic burst firing in prefrontal cortical pyramidal neurons Yun Wang and Patricia S. Goldman-Rakic PMCID: PMC387379 Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade Jean-Martin Beaulieu, Tatyana D. Sotnikova, Wei-Dong Yao, Lisa Kockeritz, James R. Woodgett, Raul R. Gainetdinov, and Marc G. Caron PMCID: PMC387380 Galanin acts as a neuroprotective factor to the hippocampus Caroline R. Elliott-Hunt, Barnaby Marsh, Andrea Bacon, Robert Pope, Penny Vanderplank, and David Wynick PMCID: PMC387381 13-cis-retinoic acid suppresses hippocampal cell division and hippocampal-dependent learning in mice James Crandall, Yasuo Sakai, Jinghua Zhang, Omanand Koul, Yann Mineur, Wim E. Crusio, and Peter McCaffery PMCID: PMC387382 Dynamic changes in N-methyl-d-aspartate receptors after closed head injury in mice: Implications for treatment of neurological and cognitive deficits Anat Biegon, Pamela A. Fry, Charles M. Paden, Alexander Alexandrovich, Jeanna Tsenter, and Esther Shohami PMCID: PMC387383 Homeostatic scaling of neuronal excitability by synaptic modulation of somatic hyperpolarization-activated Ih channels Ingrid van Welie, Johannes A. van Hooft, and Wytse J. Wadman PMCID: PMC387384 Pharmacology Impact of isotype-selective estrogen receptor agonists on ovarian function Christa Hegele-Hartung, Philip Siebel, Olaf Peters, Dirk Kosemund, Gerd Müller, Alexander Hillisch, Alexander Walter, Jörn Kraetzschmar, and Karl-Heinrich Fritzemeier PMCID: PMC387385 A role for heterodimerization of μ and δ opiate receptors in enhancing morphine analgesia Ivone Gomes, Achla Gupta, Julija Filipovska, Hazel H. Szeto, John E. Pintar, and Lakshmi A. Devi PMCID: PMC387386 Physiology Physiological changes in extracellular calcium concentration directly control osteoblast function in the absence of calciotropic hormones Melita M. Dvorak, Ashia Siddiqua, Donald T. Ward, D. Howard Carter, Sarah L. Dallas, Edward F. Nemeth, and Daniela Riccardi PMCID: PMC387387 Plant Biology Transcript profiling of early lateral root initiation Kristiina Himanen, Marnik Vuylsteke, Steffen Vanneste, Steven Vercruysse, Elodie Boucheron, Philippe Alard, Dominique Chriqui, Marc Van Montagu, Dirk Inzé, and Tom Beeckman PMCID: PMC387388 Oleic acid levels regulated by glycerolipid metabolism modulate defense gene expression in Arabidopsis Aardra Kachroo, Srivathsa C. Venugopal, Ludmila Lapchyk, Deane Falcone, David Hildebrand, and Pradeep Kachroo PMCID: PMC387389 Enhancement of folates in plants through metabolic engineering Tahzeeba Hossain, Irwin Rosenberg, Jacob Selhub, Ganesh Kishore, Roger Beachy, and Karel Schubert PMCID: PMC387390 Expression of plant protein phosphatase 2C interferes with nuclear import of the Agrobacterium T-complex protein VirD2 Yumin Tao, Praveen K. Rao, Saikat Bhattacharjee, and Stanton B. Gelvin PMCID: PMC387391 Psychology Adaptation from invisible flicker Sherif Shady, Donald I. A. MacLeod, and Heidi S. Fisher PMCID: PMC387392 Social Sciences Economic Sciences Self-enforcing climate-change treaties Prajit K. Dutta and Roy Radner PMCID: PMC387838 Corrections Proc Natl Acad Sci U S A. 2004 April 6; 101(14): 5180. doi: 10.1073/pnas.0401191101.PMCID: PMC387394 Corrects: Jonas Korlach, et al. Spontaneous nucleotide exchange in low molecular weight GTPases by fluorescently labeled γ-phosphate-linked GTP analogs. Proc Natl Acad Sci U S A. 2004 March 2; 101(9): 2800–2805. Proc Natl Acad Sci U S A. 2004 April 6; 101(14): 5180. doi: 10.1073/pnas.0401409101.PMCID: PMC387395 Corrects: Gloria Esposito, et al. Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defect. Proc Natl Acad Sci U S A. 2004 March 2; 101(9): 2993–2998. Proc Natl Acad Sci U S A. 2004 April 6; 101(14): 5180. doi: 10.1073/pnas.0401220101.PMCID: PMC387396 Corrects: Bangyan Stiles, et al. Live-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity. Proc Natl Acad Sci U S A. 2004 February 17; 101(7): 2082–2087. Proc Natl Acad Sci U S A. 2004 April 6; 101(14): 5180. doi: 10.1073/pnas.0401131101.PMCID: PMC387397 Corrects: Bruce T. Seet, et al. Analysis of an orf virus chemokine-binding protein: Shifting ligand specificities among a family of poxvirus viroceptors. Proc Natl Acad Sci U S A. 2003 December 9; 100(25): 15137–15142. Proc Natl Acad Sci U S A. 2004 April 6; 101(14): 5181. doi: 10.1073/pnas.0400883101.PMCID: PMC387398 Corrects: Mark E. Wheeler, et al. Memory's echo: Vivid remembering reactivates
sensory-specific cortex. Proc Natl Acad Sci U S A. 2000 September 26; 97(20): 11125–11129. |
