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Volume 98(13);  June 19, 2001
Colloquium Papers
Molecular kinesis in cellular function and plasticity
Henri Tiedge, Floyd E. Bloom, and Dietmar Richter
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6997–6998. doi: 10.1073/pnas.131145198.
PMCID: PMC34612
Kinesin molecular motors: Transport pathways, receptors, and human disease
Lawrence S. B. Goldstein
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6999–7003. doi: 10.1073/pnas.111145298.
PMCID: PMC34613
All kinesin superfamily protein, KIF, genes in mouse and human
Harukata Miki, Mitsutoshi Setou, Kiyofumi Kaneshiro, and Nobutaka Hirokawa
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7004–7011. doi: 10.1073/pnas.111145398.
PMCID: PMC34614
Assembly and transport of a premessenger RNP particle
Bertil Daneholt
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7012–7017. doi: 10.1073/pnas.111145498.
PMCID: PMC34615
Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome
Jack D. Keene
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7018–7024. doi: 10.1073/pnas.111145598.
PMCID: PMC34616
Spatial and temporal control of RNA stability
Arash Bashirullah, Ramona L. Cooperstock, and Howard D. Lipshitz
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7025–7028. doi: 10.1073/pnas.111145698.
PMCID: PMC34617
Molecular mechanisms of translation initiation in eukaryotes
Tatyana V. Pestova, Victoria G. Kolupaeva, Ivan B. Lomakin, Evgeny V. Pilipenko, Ivan N. Shatsky, Vadim I. Agol, and Christopher U. T. Hellen
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7029–7036. doi: 10.1073/pnas.111145798.
PMCID: PMC34618
The target of rapamycin (TOR) proteins
Brian Raught, Anne-Claude Gingras, and Nahum Sonenberg
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7037–7044. doi: 10.1073/pnas.121145898.
PMCID: PMC34619
The physiological significance of β-actin mRNA localization in determining cell polarity and directional motility
Elena A. Shestakova, Robert H. Singer, and John Condeelis
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7045–7050. doi: 10.1073/pnas.121146098.
PMCID: PMC34620
Sorting and directed transport of membrane proteins during development of hippocampal neurons in culture
M. A. Silverman, S. Kaech, M. Jareb, M. A. Burack, L. Vogt, P. Sonderegger, and G. Banker
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7051–7057. doi: 10.1073/pnas.111146198.
PMCID: PMC34621
Molecular organization of the postsynaptic specialization
Morgan Sheng
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7058–7061. doi: 10.1073/pnas.111146298.
PMCID: PMC34622
A cellular mechanism for targeting newly synthesized mRNAs to synaptic sites on dendrites
Oswald Steward and Paul F. Worley
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7062–7068. doi: 10.1073/pnas.131146398.
PMCID: PMC34623
Think globally, translate locally: What mitotic spindles and neuronal synapses have in common
Joel D. Richter
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7069–7071. doi: 10.1073/pnas.111146498.
PMCID: PMC34624
Vasopressin mRNA localization in nerve cells: Characterization of cis-acting elements and trans-acting factors
Evita Mohr, Nilima Prakash, Kerstin Vieluf, Carola Fuhrmann, Friedrich Buck, and Dietmar Richter
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7072–7079. doi: 10.1073/pnas.111146598.
PMCID: PMC34625
Local translation of classes of mRNAs that are targeted to neuronal dendrites
James Eberwine, Kevin Miyashiro, Janet Estee Kacharmina, and Christy Job
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7080–7085. doi: 10.1073/pnas.121146698.
PMCID: PMC34626
Cytoskeletal microdifferentiation: A mechanism for organizing morphological plasticity in dendrites
Stefanie Kaech, Hema Parmar, Martijn Roelandse, Caroline Bornmann, and Andrew Matus
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7086–7092. doi: 10.1073/pnas.111146798.
PMCID: PMC34627
Tracking the estrogen receptor in neurons: Implications for estrogen-induced synapse formation
Bruce McEwen, Keith Akama, Stephen Alves, Wayne G. Brake, Karen Bulloch, Susan Lee, Chenjian Li, Genevieve Yuen, and Teresa A. Milner
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7093–7100. doi: 10.1073/pnas.121146898.
PMCID: PMC34628
Synaptic regulation of protein synthesis and the fragile X protein
William T. Greenough, Anna Y. Klintsova, Scott A. Irwin, Roberto Galvez, Kathy E. Bates, and Ivan Jeanne Weiler
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7101–7106. doi: 10.1073/pnas.141145998.
PMCID: PMC34629
Commentaries
Rolling back to BOULE
Eric S. Haag
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6983–6985. doi: 10.1073/pnas.141237898.
PMCID: PMC34607
DNA structure from A to B
Richard E. Dickerson and Ho-Leung Ng
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6986–6988. doi: 10.1073/pnas.141238898.
PMCID: PMC34608
Signaling cascades: Escape from kinetic proofreading
Donald MacGlashan, Jr.
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6989–6990. doi: 10.1073/pnas.131215498.
PMCID: PMC34609
Molecular matchmaking: NNRTIs can enhance the dimerization of HIV type 1 reverse transcriptase
Stephen H. Hughes
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6991–6992. doi: 10.1073/pnas.141222698.
PMCID: PMC34610
Perspective
Thirty years on the “Broad Spectrum Revolution” and paleolithic demography
Mary C. Stiner
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6993–6996. Published online 2001 June 5. doi: 10.1073/pnas.121176198.
PMCID: PMC34611
Physical Sciences
Applied Mathematics
Titration of chaos with added noise
Chi-Sang Poon and Mauricio Barahona
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7107–7112. doi: 10.1073/pnas.131173198.
PMCID: PMC34630
Applied Physical Sciences
Indium-cadmium-oxide films having exceptional electrical conductivity and optical transparency: Clues for optimizing transparent conductors
A. Wang, J. R. Babcock, N. L. Edleman, A. W. Metz, M. A. Lane, R. Asahi, V. P. Dravid, C. R. Kannewurf, A. J. Freeman, and T. J. Marks
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7113–7116. doi: 10.1073/pnas.121188298.
PMCID: PMC34631
Chemistry
Ultrafast diffraction and structural dynamics: The nature of complex molecules far from equilibrium
Chong-Yu Ruan, Vladimir A. Lobastov, Ramesh Srinivasan, Boyd M. Goodson, Hyotcherl Ihee, and Ahmed H. Zewail
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7117–7122. Published online 2001 June 12. doi: 10.1073/pnas.131192898.
PMCID: PMC34632
Geology
From the Cover:
Aeolian dust in Colorado Plateau soils: Nutrient inputs and recent change in source
Richard Reynolds, Jayne Belnap, Marith Reheis, Paul Lamothe, and Fred Luiszer
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7123–7127. Published online 2001 June 5. doi: 10.1073/pnas.121094298.
PMCID: PMC34633
Mathematics
The effect of cultivation on the size, shape, and persistence of disease patches in fields
J. E. Truscott and C. A. Gilligan
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7128–7133. doi: 10.1073/pnas.111548698.
PMCID: PMC34634
Biological Sciences
Agricultural Sciences
The effect of cultivation on the size, shape, and persistence of disease patches in fields
J. E. Truscott and C. A. Gilligan
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7128–7133. doi: 10.1073/pnas.111548698.
PMCID: PMC34634
Biochemistry
Crystal structure of the regulatory subunit H of the V-type ATPase of Saccharomyces cerevisiae
Martin Sagermann, Tom H. Stevens, and Brian W. Matthews
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7134–7139. doi: 10.1073/pnas.131192798.
PMCID: PMC34635
Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B
Kenneth A. Simmen, Jasbir Singh, B. G. Mattias Luukkonen, Matt Lopper, Anton Bittner, Nancy E. Miller, Michael R. Jackson, Teresa Compton, and Klaus Früh
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7140–7145. Published online 2001 June 5. doi: 10.1073/pnas.121177598.
PMCID: PMC34636
Nitration of succinyl-CoA:3-oxoacid CoA-transferase in rats after endotoxin administration
Sisi Marcondes, Illarion V. Turko, and Ferid Murad
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7146–7151. doi: 10.1073/pnas.141222598.
PMCID: PMC34637
Electrospray ionization mass spectrometry analysis of changes in phospholipids in RBL-2H3 mastocytoma cells during degranulation
Pavlina T. Ivanova, Blas A. Cerda, David M. Horn, Jared S. Cohen, Fred W. McLafferty, and H. Alex Brown
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7152–7157. doi: 10.1073/pnas.131195098.
PMCID: PMC34638
Exploring the DNA-binding specificities of zinc fingers with DNA microarrays
Martha L. Bulyk, Xiaohua Huang, Yen Choo, and George M. Church
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7158–7163. Published online 2001 June 12. doi: 10.1073/pnas.111163698.
PMCID: PMC34639
Tolerance of human MSH2+/− lymphoblastoid cells to the methylating agent temozolomide
Giancarlo Marra, Stefania D'Atri, Chantal Corti, Laura Bonmassar, Maria Sofia Cattaruzza, Pascal Schweizer, Karl Heinimann, Zdena Bartosova, Minna Nyström-Lahti, and Josef Jiricny
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7164–7169. doi: 10.1073/pnas.121136498.
PMCID: PMC34640
Copper-catalyzed oxidation of the recombinant SHa(29–231) prion protein
Jesús R. Requena, Darlene Groth, Giuseppe Legname, Earl R. Stadtman, Stanley B. Prusiner, and Rodney L. Levine
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7170–7175. Published online 2001 June 12. doi: 10.1073/pnas.121190898.
PMCID: PMC34641
Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode α1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis
Byung-Taek Kim, Hiroshi Kitagawa, Jun-ichi Tamura, Toshiyuki Saito, Marion Kusche-Gullberg, Ulf Lindahl, and Kazuyuki Sugahara
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7176–7181. Published online 2001 June 5. doi: 10.1073/pnas.131188498.
PMCID: PMC34642
Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome
Omar A. Ibrahimi, Anna V. Eliseenkova, Alexander N. Plotnikov, Kai Yu, David M. Ornitz, and Moosa Mohammadi
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7182–7187. Published online 2001 June 5. doi: 10.1073/pnas.121183798.
PMCID: PMC34643
From the Cover:
Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase
Gilda Tachedjian, Marianna Orlova, Stefan G. Sarafianos, Edward Arnold, and Stephen P. Goff
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7188–7193. doi: 10.1073/pnas.121055998.
PMCID: PMC34644
Complementary intrastrand base pairing during initiation of Herpes simplex virus type 1 DNA replication
Alireza Aslani, Bertil Macao, Stina Simonsson, and Per Elias
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7194–7199. doi: 10.1073/pnas.121177198.
PMCID: PMC34645
Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor
Hui-Kuan Lin, Shuyuan Yeh, Hong-Yo Kang, and Chawnshang Chang
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7200–7205. Published online 2001 June 12. doi: 10.1073/pnas.121173298.
PMCID: PMC34646
Identification and characterization of a lysosomal transporter for small neutral amino acids
Corinne Sagné, Cendra Agulhon, Philippe Ravassard, Michèle Darmon, Michel Hamon, Salah El Mestikawy, Bruno Gasnier, and Bruno Giros
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7206–7211. Published online 2001 June 5. doi: 10.1073/pnas.121183498.
PMCID: PMC34647
Nitric oxide partitioning into mitochondrial membranes and the control of respiration at cytochrome c oxidase
Sruti Shiva, Paul S. Brookes, Rakesh P. Patel, Peter G. Anderson, and Victor M. Darley-Usmar
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7212–7217. doi: 10.1073/pnas.131128898.
PMCID: PMC34648
Mutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasia
Yanwen Chen, Sean S. Molloy, Laurel Thomas, Jay Gambee, Hans Peter Bächinger, Betsy Ferguson, Jonathan Zonana, Gary Thomas, and Nicholas P. Morris
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7218–7223. doi: 10.1073/pnas.131076098.
PMCID: PMC34649
A pentacyclic reaction intermediate of riboflavin synthase
Boris Illarionov, Wolfgang Eisenreich, and Adelbert Bacher
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7224–7229. Published online 2001 June 12. doi: 10.1073/pnas.131610698.
PMCID: PMC34650
Crystal structure of an anticoagulant protein in complex with the Gla domain of factor X
Hiroshi Mizuno, Zui Fujimoto, Hideko Atoda, and Takashi Morita
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7230–7234. Published online 2001 June 12. doi: 10.1073/pnas.131179698.
PMCID: PMC34651
Biophysics
Titration of chaos with added noise
Chi-Sang Poon and Mauricio Barahona
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7107–7112. doi: 10.1073/pnas.131173198.
PMCID: PMC34630
A quantitative model for membrane fusion based on low-energy intermediates
Peter I. Kuzmin, Joshua Zimmerberg, Yuri A. Chizmadzhev, and Fredric S. Cohen
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7235–7240. Published online 2001 June 12. doi: 10.1073/pnas.121191898.
PMCID: PMC34652
Use of chimeric proteins to investigate the role of transporter associated with antigen processing (TAP) structural domains in peptide binding and translocation
Shikha Arora, Philip Edward Lapinski, and Malini Raghavan
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7241–7246. doi: 10.1073/pnas.131132198.
PMCID: PMC34653
Kinetics and mechanism of DNA uptake into the cell nucleus
H. Salman, D. Zbaida, Y. Rabin, D. Chatenay, and M. Elbaum
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7247–7252. Published online 2001 June 5. doi: 10.1073/pnas.121067698.
PMCID: PMC34654
Simple neural networks for the amplification and utilization of small changes in neuron firing rates
Robert K. Adair
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7253–7258. Published online 2001 June 12. doi: 10.1073/pnas.121171598.
PMCID: PMC34655
Partial molar volume, surface area, and hydration changes for equilibrium unfolding and formation of aggregation transition state: High-pressure and cosolute studies on recombinant human IFN-γ
Jonathan N. Webb, Serena D. Webb, Jeffrey L. Cleland, John F. Carpenter, and Theodore W. Randolph
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7259–7264. Published online 2001 May 29. doi: 10.1073/pnas.131194798.
PMCID: PMC34656
From the Cover:
A crystallographic map of the transition from B-DNA to A-DNA
Jeffrey M. Vargason, Keith Henderson, and P. Shing Ho
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7265–7270. Published online 2001 June 5. doi: 10.1073/pnas.121176898.
PMCID: PMC34657
Cell Biology
Afipia felis induces uptake by macrophages directly into a nonendocytic compartment
Anja Lührmann, Karin Streker, Anja Schüttfort, Justin J. D. Daniels, and Albert Haas
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7271–7276. Published online 2001 June 12. doi: 10.1073/pnas.121190398.
PMCID: PMC34658
Thrombin induces the release of the Y-box protein dbpB from mRNA: A mechanism of transcriptional activation
Olga I. Stenina, Kristin M. Shaneyfelt, and Paul E. DiCorleto
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7277–7282. Published online 2001 June 5. doi: 10.1073/pnas.121592298.
PMCID: PMC34659
Carbon- and nitrogen-quality signaling to translation are mediated by distinct GATA-type transcription factors
Finny G. Kuruvilla, Alykhan F. Shamji, and Stuart L. Schreiber
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7283–7288. doi: 10.1073/pnas.121186898.
PMCID: PMC34660
From the Cover:
Unexpected signals in a system subject to kinetic proofreading
Zhao-Jun Liu, Hana Haleem-Smith, Huaxian Chen, and Henry Metzger
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7289–7294. Published online 2001 May 22. doi: 10.1073/pnas.121171998.
PMCID: PMC34661
Kinetic proofreading models for cell signaling predict ways to escape kinetic proofreading
William S. Hlavacek, Antonio Redondo, Henry Metzger, Carla Wofsy, and Byron Goldstein
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7295–7300. Published online 2001 June 5. doi: 10.1073/pnas.121172298.
PMCID: PMC34662
l-Arginine-dependent suppression of apoptosis in Trypanosoma cruzi: Contribution of the nitric oxide and polyamine pathways
Lucía Piacenza, Gonzalo Peluffo, and Rafael Radi
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7301–7306. Published online 2001 June 12. doi: 10.1073/pnas.121520398.
PMCID: PMC34663
Corneal collagen fibril structure in three dimensions: Structural insights into fibril assembly, mechanical properties, and tissue organization
David F. Holmes, Christopher J. Gilpin, Clair Baldock, Ulrike Ziese, Abraham J. Koster, and Karl E. Kadler
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7307–7312. Published online 2001 June 5. doi: 10.1073/pnas.111150598.
PMCID: PMC34664
Protein misfolding and temperature up-shift cause G1 arrest via a common mechanism dependent on heat shock factor in Saccharomyces cerevisiae
Eleanor W. Trotter, Lumilla Berenfeld, Sue Ann Krause, Gregory A. Petsko, and Joseph V. Gray
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7313–7318. doi: 10.1073/pnas.121172998.
PMCID: PMC34665
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis
Tammy Bowman, Martin A. Broome, Dominic Sinibaldi, Walker Wharton, W. J. Pledger, John M. Sedivy, Rosalyn Irby, Timothy Yeatman, Sara A. Courtneidge, and Richard Jove
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7319–7324. Published online 2001 June 12. doi: 10.1073/pnas.131568898.
PMCID: PMC34666
Protein kinase Cdc15 activates the Dbf2-Mob1 kinase complex
Angie S. Mah, Joanne Jang, and Raymond J. Deshaies
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7325–7330. Published online 2001 June 12. doi: 10.1073/pnas.141098998.
PMCID: PMC34667
Developmental Biology
Oxygen deprivation causes suspended animation in the zebrafish embryo
Pamela A. Padilla and Mark B. Roth
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7331–7335. Published online 2001 June 12. doi: 10.1073/pnas.131213198.
PMCID: PMC34668
Endogenous Msx1 antisense transcript: In vivo and in vitro evidences, structure, and potential involvement in skeleton development in mammals
C. Blin-Wakkach, F. Lezot, S. Ghoul-Mazgar, D. Hotton, S. Monteiro, C. Teillaud, L. Pibouin, S. Orestes-Cardoso, P. Papagerakis, M. Macdougall, B. Robert, and A. Berdal
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7336–7341. Published online 2001 June 5. doi: 10.1073/pnas.131497098.
PMCID: PMC34669
The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila
Nancy Fossett, Sergei G. Tevosian, Kathleen Gajewski, Qian Zhang, Stuart H. Orkin, and Robert A. Schulz
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7342–7347. Published online 2001 June 12. doi: 10.1073/pnas.131215798.
PMCID: PMC34670
Timing of metamorphosis and the onset of the negative feedback loop between the thyroid gland and the pituitary is controlled by type II iodothyronine deiodinase in Xenopus laevis
Haochu Huang, Liquan Cai, Benjamin F. Remo, and Donald D. Brown
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7348–7353. Published online 2001 June 12. doi: 10.1073/pnas.131198998.
PMCID: PMC34671
The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis
Chun Li Zhang, Timothy A. McKinsey, and Eric N. Olson
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7354–7359. Published online 2001 June 5. doi: 10.1073/pnas.131198498.
PMCID: PMC34672
Nuclear hormone receptor CHR3 is a critical regulator of all four larval molts of the nematode Caenorhabditis elegans
Marta Kostrouchova, Michael Krause, Zdenek Kostrouch, and Joseph Edward Rall
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7360–7365. doi: 10.1073/pnas.131171898.
PMCID: PMC34673
Ecology
Corticosterone levels predict survival probabilities of Galápagos marine iguanas during El Niño events
L. Michael Romero and Martin Wikelski
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7366–7370. doi: 10.1073/pnas.131091498.
PMCID: PMC34674
Tracking wakes: The nocturnal predatory strategy of piscivorous catfish
Kirsten Pohlmann, Frank W. Grasso, and Thomas Breithaupt
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7371–7374. Published online 2001 June 5. doi: 10.1073/pnas.121026298.
PMCID: PMC34675
Evolution
Evolutionary EST analysis identifies rapidly evolving male reproductive proteins in Drosophila
Willie J. Swanson, Andrew G. Clark, Heidi M. Waldrip-Dail, Mariana F. Wolfner, and Charles F. Aquadro
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7375–7379. Published online 2001 June 12. doi: 10.1073/pnas.131568198.
PMCID: PMC34676
On the origin of and phylogenetic relationships among living amphibians
Rafael Zardoya and Axel Meyer
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7380–7383. Published online 2001 June 5. doi: 10.1073/pnas.111455498.
PMCID: PMC34677
Retroposon analysis of major cetacean lineages: The monophyly of toothed whales and the paraphyly of river dolphins
Masato Nikaido, Fumio Matsuno, Healy Hamilton, Robert L. Brownell, Jr., Ying Cao, Wang Ding, Zhu Zuoyan, Andrew M. Shedlock, R. Ewan Fordyce, Masami Hasegawa, and Norihiro Okada
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7384–7389. doi: 10.1073/pnas.121139198.
PMCID: PMC34678
Genomic analysis of orthologous mouse and human olfactory receptor loci
Robert P. Lane, Tyler Cutforth, Janet Young, Maria Athanasiou, Cynthia Friedman, Lee Rowen, Glen Evans, Richard Axel, Leroy Hood, and Barbara J. Trask
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7390–7395. doi: 10.1073/pnas.131215398.
PMCID: PMC34679
Nucleotide sequences provide evidence of genetic exchange among distantly related lineages of Trypanosoma cruzi
Carlos A. Machado and Francisco J. Ayala
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7396–7401. doi: 10.1073/pnas.121187198.
PMCID: PMC34680
Genetics
Genetic and environmental factors modify bovine spongiform encephalopathy incubation period in mice
Katerina Manolakou, Jenny Beaton, Irene McConnell, Christine Farquar, Jean Manson, Nicholas D. Hastie, Moira Bruce, and Ian J. Jackson
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7402–7407. Published online 2001 June 12. doi: 10.1073/pnas.121172098.
PMCID: PMC34681
Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock
Ping Cheng, Yuhong Yang, and Yi Liu
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7408–7413. doi: 10.1073/pnas.121170298.
PMCID: PMC34682
From the Cover:
A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans
Eugene Yujun Xu, Frederick L. Moore, and Renee A. Reijo Pera
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7414–7419. Published online 2001 June 5. doi: 10.1073/pnas.131090498.
PMCID: PMC34683
Screening insertion libraries for mutations in many genes simultaneously using DNA microarrays
Ramamurthy Mahalingam and Nina Fedoroff
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7420–7425. doi: 10.1073/pnas.121189598.
PMCID: PMC34684
Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli
Jeffrey O. Blaisdell and Susan S. Wallace
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7426–7430. Published online 2001 June 12. doi: 10.1073/pnas.131077798.
PMCID: PMC34685
Immunology
Distinct functions and cooperative interaction of the subunits of the transporter associated with antigen processing (TAP)
Jaana T. Karttunen, Paul J. Lehner, Soma Sen Gupta, Eric W. Hewitt, and Peter Cresswell
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7431–7436. Published online 2001 May 29. doi: 10.1073/pnas.121180198.
PMCID: PMC34686
Positive selection of an MHC class-I restricted TCR in the absence of classical MHC class I molecules
Madelon M. Maurice, Dina S. Gould, John Carroll, Yulia Vugmeyster, and Hidde L. Ploegh
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7437–7442. Published online 2001 June 12. doi: 10.1073/pnas.141143298.
PMCID: PMC34687
Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models
Brian Cao, Yanli Su, Marianne Oskarsson, Ping Zhao, Eric J. Kort, Robert J. Fisher, Ling-Mei Wang, and George F. Vande Woude
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7443–7448. doi: 10.1073/pnas.131200498.
PMCID: PMC34688
Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP
Michael J. Czar, Ellen N. Kersh, Lilia A. Mijares, Gibson Lanier, Jennifer Lewis, George Yap, Amy Chen, Alan Sher, Colin S. Duckett, Rafi Ahmed, and Pamela L. Schwartzberg
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7449–7454. Published online 2001 June 12. doi: 10.1073/pnas.131193098.
PMCID: PMC34689
Clonable progenitors committed to the T lymphocyte lineage in the mouse bone marrow; use of an extrathymic pathway
Sussan Dejbakhsh-Jones, Marcos E. García-Ojeda, Devavani Chatterjea-Matthes, Defu Zeng, and Samuel Strober
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7455–7460. Published online 2001 June 5. doi: 10.1073/pnas.131559798.
PMCID: PMC34690
How the immune system works to protect the host from infection: A personal view
Charles A. Janeway, Jr.
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7461–7468. Published online 2001 June 5. doi: 10.1073/pnas.131202998.
PMCID: PMC34691
Medical Sciences
Conditional and targeted overexpression of vascular chymase causes hypertension in transgenic mice
Haisong Ju, Robert Gros, Xiaomang You, Sarah Tsang, Mansoor Husain, and Marlene Rabinovitch
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7469–7474. doi: 10.1073/pnas.131147598.
PMCID: PMC34692
Evidence for a circulating islet cell growth factor in insulin-resistant states
Sarah N. Flier, Rohit N. Kulkarni, and C. Ronald Kahn
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7475–7480. Published online 2001 June 12. doi: 10.1073/pnas.131192998.
PMCID: PMC34693
Excessive tumor-elaborated VEGF and its neutralization define a lethal paraneoplastic syndrome
Alex K. Wong, Myra Alfert, Diego H. Castrillon, Qiong Shen, Jocelyn Holash, George D. Yancopoulos, and Lynda Chin
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7481–7486. Published online 2001 June 12. doi: 10.1073/pnas.121192298.
PMCID: PMC34694
γ-Secretase inhibitors repress thymocyte development
Brandon K. Hadland, Nancy R. Manley, Dong-ming Su, Gregory D. Longmore, Chad L. Moore, Michael S. Wolfe, Eric H. Schroeter, and Raphael Kopan
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7487–7491. doi: 10.1073/pnas.131202798.
PMCID: PMC34695
CML66, a broadly immunogenic tumor antigen, elicits a humoral immune response associated with remission of chronic myelogenous leukemia
Xiao-Feng Yang, Catherine J. Wu, Stephen McLaughlin, Antoinette Chillemi, Kathy S. Wang, Christine Canning, Edwin P. Alyea, Philip Kantoff, Robert J. Soiffer, Glenn Dranoff, and Jerome Ritz
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7492–7497. doi: 10.1073/pnas.131590998.
PMCID: PMC34696
Targeted ablation of the 25-hydroxyvitamin D 1α-hydroxylase enzyme: Evidence for skeletal, reproductive, and immune dysfunction
Dibyendu K. Panda, Dengshun Miao, Michel L. Tremblay, Jacinthe Sirois, Riaz Farookhi, Geoffrey N. Hendy, and David Goltzman
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7498–7503. doi: 10.1073/pnas.131029498.
PMCID: PMC34697
The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis
Koen Dreijerink, Eleonora Braga, Igor Kuzmin, Laura Geil, Fuh-Mei Duh, Debora Angeloni, Berton Zbar, Michael I. Lerman, Eric J. Stanbridge, John D. Minna, Alexei Protopopov, Jingfeng Li, Vladimir Kashuba, George Klein, and Eugene R. Zabarovsky
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7504–7509. Published online 2001 June 5. doi: 10.1073/pnas.131216298.
PMCID: PMC34698
Omega 3 but not omega 6 fatty acids inhibit AP-1 activity and cell transformation in JB6 cells
Guangming Liu, Douglas M. Bibus, Ann M. Bode, Wei-Ya Ma, Ralph T. Holman, and Zigang Dong
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7510–7515. doi: 10.1073/pnas.131195198.
PMCID: PMC34699
Ullrich scleroatonic muscular dystrophy is caused by recessive mutations in collagen type VI
Olga Camacho Vanegas, Enrico Bertini, Rui-Zhu Zhang, Stefania Petrini, Claudia Minosse, Patrizia Sabatelli, Betti Giusti, Mon-Li Chu, and Guglielmina Pepe
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7516–7521. Published online 2001 May 29. doi: 10.1073/pnas.121027598.
PMCID: PMC34700
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance
Jason K. Kim, Jonathan J. Fillmore, Yan Chen, Chunli Yu, Irene K. Moore, Marc Pypaert, E. Peer Lutz, Yuko Kako, Wanda Velez-Carrasco, Ira J. Goldberg, Jan L. Breslow, and Gerald I. Shulman
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7522–7527. Published online 2001 June 5. doi: 10.1073/pnas.121164498.
PMCID: PMC34701
In vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapy
Doron Shabat, Holger N. Lode, Ursula Pertl, Ralph A. Reisfeld, Christoph Rader, Richard A. Lerner, and Carlos F. Barbas, III
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7528–7533. Published online 2001 June 12. doi: 10.1073/pnas.131187998.
PMCID: PMC34702
Microbiology
Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding α-crystallin
David R. Sherman, Martin Voskuil, Dirk Schnappinger, Reiling Liao, Maria I. Harrell, and Gary K. Schoolnik
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7534–7539. doi: 10.1073/pnas.121172498.
PMCID: PMC34703
Light regulation of type IV pilus-dependent motility by chemosensor-like elements in Synechocystis PCC6803
Devaki Bhaya, Akiko Takahashi, and Arthur R. Grossman
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7540–7545. Published online 2001 June 12. doi: 10.1073/pnas.131201098.
PMCID: PMC34704
A novel application of gene arrays: Escherichia coli array provides insight into the biology of the obligate endosymbiont of tsetse flies
Leyla Akman and Serap Aksoy
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7546–7551. Published online 2001 June 12. doi: 10.1073/pnas.131057498.
PMCID: PMC34705
Multilocus analysis of extracellular putative virulence proteins made by group A Streptococcus: Population genetics, human serologic response, and gene transcription
Sean D. Reid, Nicole M. Green, Julie K. Buss, Benfang Lei, and James M. Musser
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7552–7557. doi: 10.1073/pnas.121188598.
PMCID: PMC34706
Neurobiology
Dopamine receptor regulating factor, DRRF: A zinc finger transcription factor
Cheol Kyu Hwang, Ursula M. D'Souza, Amelia J. Eisch, Shunsuke Yajima, Claas-Hinrich Lammers, Young Yang, Sang-Hyeon Lee, Yong-Man Kim, Eric J. Nestler, and M. Maral Mouradian
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7558–7563. Published online 2001 June 5. doi: 10.1073/pnas.121635798.
PMCID: PMC34707
Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R
Andreas W. Sailer, Hideki Sano, Zhizhen Zeng, Terrence P. McDonald, Jie Pan, Sheng-Shung Pong, Scott D. Feighner, Carina P. Tan, Takehiro Fukami, Hisashi Iwaasa, Donna L. Hreniuk, Nancy R. Morin, Sharon J. Sadowski, Makoto Ito, Masahiko Ito, Alka Bansal, Betty Ky, David J. Figueroa, Qingping Jiang, Christopher P. Austin, Douglas J. MacNeil, Akane Ishihara, Masaki Ihara, Akio Kanatani, Lex H. T. Van der Ploeg, Andrew D. Howard, and Qingyun Liu
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7564–7569. Published online 2001 June 12. doi: 10.1073/pnas.121170598.
PMCID: PMC34708
Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor
K. Lewis, C. Li, M. H. Perrin, A. Blount, K. Kunitake, C. Donaldson, J. Vaughan, T. M. Reyes, J. Gulyas, W. Fischer, L. Bilezikjian, J. Rivier, P. E. Sawchenko, and W. W. Vale
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7570–7575. doi: 10.1073/pnas.121165198.
PMCID: PMC34709
Identification and characterization of a melanin-concentrating hormone receptor
Songzhu An, Gene Cutler, Jack Jiagang Zhao, Shu-Gui Huang, Hui Tian, Wanbo Li, Lingming Liang, Miki Rich, Amy Bakleh, Juan Du, Jin-Long Chen, and Kang Dai
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7576–7581. doi: 10.1073/pnas.131200698.
PMCID: PMC34710
Synaptic sprouting increases the uptake capacities of motoneurons in amyotrophic lateral sclerosis mice
Stéphanie Millecamps, Delphine Nicolle, Irène Ceballos-Picot, Jacques Mallet, and Martine Barkats
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7582–7587. Published online 2001 June 12. doi: 10.1073/pnas.131031098.
PMCID: PMC34711
Evolution and divergence of sodium channel genes in vertebrates
Gregory F. Lopreato, Ying Lu, Amber Southwell, Nigel S. Atkinson, David M. Hillis, Thomas P. Wilcox, and Harold H. Zakon
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7588–7592. doi: 10.1073/pnas.131171798.
PMCID: PMC34712
Effects of anesthesia on functional activation of cerebral blood flow and metabolism
Yasuaki Nakao, Yoshiaki Itoh, Tang-Yong Kuang, Michelle Cook, Jane Jehle, and Louis Sokoloff
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7593–7598. Published online 2001 June 5. doi: 10.1073/pnas.121179898.
PMCID: PMC34713
Pharmacology
Antillatoxin is a marine cyanobacterial toxin that potently activates voltage-gated sodium channels
W. I. Li, F. W. Berman, T. Okino, F. Yokokawa, T. Shioiri, W. H. Gerwick, and T. F. Murray
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7599–7604. doi: 10.1073/pnas.121085898.
PMCID: PMC34714
Phenserine regulates translation of β-amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development
Karen T. Y. Shaw, Tadanobu Utsuki, Jack Rogers, Qian-Sheng Yu, Kumar Sambamurti, Arnold Brossi, Yuan-Wen Ge, Debomoy K. Lahiri, and Nigel H. Greig
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7605–7610. Published online 2001 June 12. doi: 10.1073/pnas.131152998.
PMCID: PMC34715
Grafts of adenosine-releasing cells suppress seizures in kindling epilepsy
Alexander Huber, Vivianne Padrun, Nicole Déglon, Patrick Aebischer, Hanns Möhler, and Detlev Boison
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7611–7616. Published online 2001 June 12. doi: 10.1073/pnas.131102898.
PMCID: PMC34716
Heteromeric association creates a P2Y-like adenosine receptor
Kazuaki Yoshioka, Osamu Saitoh, and Hiroyasu Nakata
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7617–7622. Published online 2001 June 5. doi: 10.1073/pnas.121587098.
PMCID: PMC34717
Physiology
Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channels
Antonio J. Carrasco, Petras P. Dzeja, Alexey E. Alekseev, Darko Pucar, Leonid V. Zingman, M. Roselle Abraham, Denice Hodgson, Martin Bienengraeber, Michel Puceat, Edwin Janssen, Be Wieringa, and Andre Terzic
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7623–7628. Published online 2001 June 5. doi: 10.1073/pnas.121038198.
PMCID: PMC34718
Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin
Gitta Neufang, Gerhard Fürstenberger, Markus Heidt, Friedrich Marks, and Karin Müller-Decker
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7629–7634. Published online 2001 May 29. doi: 10.1073/pnas.121574098.
PMCID: PMC34719
Plant Biology
Transcription factor RF2a alters expression of the rice tungro bacilliform virus promoter in transgenic tobacco plants
Silvana Petruccelli, Shunhong Dai, Rosa Carcamo, Yanhai Yin, Shouyi Chen, and Roger N. Beachy
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7635–7640. Published online 2001 June 5. doi: 10.1073/pnas.121186398.
PMCID: PMC34720
Social Sciences
Anthropology
Thirty years on the “Broad Spectrum Revolution” and paleolithic demography
Mary C. Stiner
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6993–6996. Published online 2001 June 5. doi: 10.1073/pnas.121176198.
PMCID: PMC34611
Ornaments of the earliest Upper Paleolithic: New insights from the Levant
Steven L. Kuhn, Mary C. Stiner, David S. Reese, and Erksin Güleç
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7641–7646. Published online 2001 June 5. doi: 10.1073/pnas.121590798.
PMCID: PMC34721
Corrections
Correction
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7647.
PMCID: PMC55962
Corrects: Lu Tian, et al. Blocking histone deacetylation in Arabidopsis induces pleiotropic effects on plant gene regulation and development. Proc Natl Acad Sci U S A. 2001 January 2; 98(1): 200–205.
Correction
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7647.
PMCID: PMC55963
Corrects: T Kakutani, et al. Developmental abnormalities and epimutations associated with DNA hypomethylation mutations. Proc Natl Acad Sci U S A. 1996 October 29; 93(22): 12406–12411.
Correction
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7647. Published online 2001 June 12.
PMCID: PMC55964
Corrects: Liyanage P. Perera, et al. Comparative assessment of virulence of recombinant vaccinia viruses expressing IL-2 and IL-15 in immunodeficient mice. Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5146–5151.
Correction
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7647. Published online 2001 June 12.
PMCID: PMC55965
Corrects: Alvin Berger, et al. Anandamide and diet: Inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets. Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6402–6406.
Correction
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7647. Published online 2001 June 12.
PMCID: PMC55966
Corrects: C. Ronald Geyer, et al. “Mutagenesis” by peptide aptamers identifies genetic network members and pathway connections. Proc Natl Acad Sci U S A. 1999 July 20; 96(15): 8567–8572.
Correction
Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7647.
PMCID: PMC55967
Corrects: Baljit S. Khakh, et al. Activation-dependent changes in receptor distribution and dendritic morphology in hippocampal neurons expressing P2X2-green fluorescent protein receptors. Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5288–5293.
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