| | This journal provides immediate access to some articles. Colloquium Papers Molecular kinesis in cellular function and plasticity Henri Tiedge, Floyd E. Bloom, and Dietmar Richter Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6997–6998. doi: 10.1073/pnas.131145198.PMCID: PMC34612 Kinesin molecular motors: Transport pathways, receptors, and human disease Lawrence S. B. Goldstein Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6999–7003. doi: 10.1073/pnas.111145298.PMCID: PMC34613 All kinesin superfamily protein, KIF, genes in mouse and human Harukata Miki, Mitsutoshi Setou, Kiyofumi Kaneshiro, and Nobutaka Hirokawa Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7004–7011. doi: 10.1073/pnas.111145398.PMCID: PMC34614 Assembly and transport of a premessenger RNP particle Bertil Daneholt Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7012–7017. doi: 10.1073/pnas.111145498.PMCID: PMC34615 Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome Jack D. Keene Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7018–7024. doi: 10.1073/pnas.111145598.PMCID: PMC34616 Spatial and temporal control of RNA stability Arash Bashirullah, Ramona L. Cooperstock, and Howard D. Lipshitz Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7025–7028. doi: 10.1073/pnas.111145698.PMCID: PMC34617 Molecular mechanisms of translation initiation in eukaryotes Tatyana V. Pestova, Victoria G. Kolupaeva, Ivan B. Lomakin, Evgeny V. Pilipenko, Ivan N. Shatsky, Vadim I. Agol, and Christopher U. T. Hellen Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7029–7036. doi: 10.1073/pnas.111145798.PMCID: PMC34618 The target of rapamycin (TOR) proteins Brian Raught, Anne-Claude Gingras, and Nahum Sonenberg Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7037–7044. doi: 10.1073/pnas.121145898.PMCID: PMC34619 The physiological significance of β-actin mRNA localization in determining cell polarity and directional motility Elena A. Shestakova, Robert H. Singer, and John Condeelis Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7045–7050. doi: 10.1073/pnas.121146098.PMCID: PMC34620 Sorting and directed transport of membrane proteins during development of hippocampal neurons in culture M. A. Silverman, S. Kaech, M. Jareb, M. A. Burack, L. Vogt, P. Sonderegger, and G. Banker Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7051–7057. doi: 10.1073/pnas.111146198.PMCID: PMC34621 Molecular organization of the postsynaptic specialization Morgan Sheng Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7058–7061. doi: 10.1073/pnas.111146298.PMCID: PMC34622 A cellular mechanism for targeting newly synthesized mRNAs to synaptic sites on dendrites Oswald Steward and Paul F. Worley Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7062–7068. doi: 10.1073/pnas.131146398.PMCID: PMC34623 Think globally, translate locally: What mitotic spindles and neuronal synapses have in common Joel D. Richter Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7069–7071. doi: 10.1073/pnas.111146498.PMCID: PMC34624 Vasopressin mRNA localization in nerve cells: Characterization of cis-acting elements and trans-acting factors Evita Mohr, Nilima Prakash, Kerstin Vieluf, Carola Fuhrmann, Friedrich Buck, and Dietmar Richter Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7072–7079. doi: 10.1073/pnas.111146598.PMCID: PMC34625 Local translation of classes of mRNAs that are targeted to neuronal dendrites James Eberwine, Kevin Miyashiro, Janet Estee Kacharmina, and Christy Job Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7080–7085. doi: 10.1073/pnas.121146698.PMCID: PMC34626 Cytoskeletal microdifferentiation: A mechanism for organizing morphological plasticity in dendrites Stefanie Kaech, Hema Parmar, Martijn Roelandse, Caroline Bornmann, and Andrew Matus Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7086–7092. doi: 10.1073/pnas.111146798.PMCID: PMC34627 Tracking the estrogen receptor in neurons: Implications for estrogen-induced synapse formation Bruce McEwen, Keith Akama, Stephen Alves, Wayne G. Brake, Karen Bulloch, Susan Lee, Chenjian Li, Genevieve Yuen, and Teresa A. Milner Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7093–7100. doi: 10.1073/pnas.121146898.PMCID: PMC34628 Synaptic regulation of protein synthesis and the fragile X protein William T. Greenough, Anna Y. Klintsova, Scott A. Irwin, Roberto Galvez, Kathy E. Bates, and Ivan Jeanne Weiler Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7101–7106. doi: 10.1073/pnas.141145998.PMCID: PMC34629 Commentaries Rolling back to BOULE Eric S. Haag Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6983–6985. doi: 10.1073/pnas.141237898.PMCID: PMC34607 DNA structure from A to B Richard E. Dickerson and Ho-Leung Ng Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6986–6988. doi: 10.1073/pnas.141238898.PMCID: PMC34608 Signaling cascades: Escape from kinetic proofreading Donald MacGlashan, Jr. Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6989–6990. doi: 10.1073/pnas.131215498.PMCID: PMC34609 Molecular matchmaking: NNRTIs can enhance the dimerization of HIV type 1 reverse transcriptase Stephen H. Hughes Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6991–6992. doi: 10.1073/pnas.141222698.PMCID: PMC34610 Perspective Thirty years on the “Broad Spectrum Revolution” and paleolithic demography Mary C. Stiner Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6993–6996. Published online 2001 June 5. doi: 10.1073/pnas.121176198.PMCID: PMC34611 Physical Sciences Applied Mathematics Titration of chaos with added noise Chi-Sang Poon and Mauricio Barahona Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7107–7112. doi: 10.1073/pnas.131173198.PMCID: PMC34630 Applied Physical Sciences Indium-cadmium-oxide films having exceptional electrical conductivity and optical transparency: Clues for optimizing transparent conductors A. Wang, J. R. Babcock, N. L. Edleman, A. W. Metz, M. A. Lane, R. Asahi, V. P. Dravid, C. R. Kannewurf, A. J. Freeman, and T. J. Marks Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7113–7116. doi: 10.1073/pnas.121188298.PMCID: PMC34631 Chemistry Ultrafast diffraction and structural dynamics: The nature of complex molecules far from equilibrium Chong-Yu Ruan, Vladimir A. Lobastov, Ramesh Srinivasan, Boyd M. Goodson, Hyotcherl Ihee, and Ahmed H. Zewail Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7117–7122. Published online 2001 June 12. doi: 10.1073/pnas.131192898.PMCID: PMC34632 Geology From the Cover: Aeolian dust in Colorado Plateau soils: Nutrient inputs and recent change in source Richard Reynolds, Jayne Belnap, Marith Reheis, Paul Lamothe, and Fred Luiszer Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7123–7127. Published online 2001 June 5. doi: 10.1073/pnas.121094298.PMCID: PMC34633 Mathematics The effect of cultivation on the size, shape, and persistence of disease patches in fields J. E. Truscott and C. A. Gilligan Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7128–7133. doi: 10.1073/pnas.111548698.PMCID: PMC34634 Biological Sciences Agricultural Sciences The effect of cultivation on the size, shape, and persistence of disease patches in fields J. E. Truscott and C. A. Gilligan Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7128–7133. doi: 10.1073/pnas.111548698.PMCID: PMC34634 Biochemistry Crystal structure of the regulatory subunit H of the V-type ATPase of Saccharomyces cerevisiae Martin Sagermann, Tom H. Stevens, and Brian W. Matthews Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7134–7139. doi: 10.1073/pnas.131192798.PMCID: PMC34635 Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B Kenneth A. Simmen, Jasbir Singh, B. G. Mattias Luukkonen, Matt Lopper, Anton Bittner, Nancy E. Miller, Michael R. Jackson, Teresa Compton, and Klaus Früh Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7140–7145. Published online 2001 June 5. doi: 10.1073/pnas.121177598.PMCID: PMC34636 Nitration of succinyl-CoA:3-oxoacid CoA-transferase in rats after endotoxin administration Sisi Marcondes, Illarion V. Turko, and Ferid Murad Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7146–7151. doi: 10.1073/pnas.141222598.PMCID: PMC34637 Electrospray ionization mass spectrometry analysis of changes in phospholipids in RBL-2H3 mastocytoma cells during degranulation Pavlina T. Ivanova, Blas A. Cerda, David M. Horn, Jared S. Cohen, Fred W. McLafferty, and H. Alex Brown Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7152–7157. doi: 10.1073/pnas.131195098.PMCID: PMC34638 Exploring the DNA-binding specificities of zinc fingers with DNA microarrays Martha L. Bulyk, Xiaohua Huang, Yen Choo, and George M. Church Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7158–7163. Published online 2001 June 12. doi: 10.1073/pnas.111163698.PMCID: PMC34639 Tolerance of human MSH2+/− lymphoblastoid cells to the methylating agent temozolomide Giancarlo Marra, Stefania D'Atri, Chantal Corti, Laura Bonmassar, Maria Sofia Cattaruzza, Pascal Schweizer, Karl Heinimann, Zdena Bartosova, Minna Nyström-Lahti, and Josef Jiricny Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7164–7169. doi: 10.1073/pnas.121136498.PMCID: PMC34640 Copper-catalyzed oxidation of the recombinant SHa(29–231) prion protein Jesús R. Requena, Darlene Groth, Giuseppe Legname, Earl R. Stadtman, Stanley B. Prusiner, and Rodney L. Levine Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7170–7175. Published online 2001 June 12. doi: 10.1073/pnas.121190898.PMCID: PMC34641 Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode α1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis Byung-Taek Kim, Hiroshi Kitagawa, Jun-ichi Tamura, Toshiyuki Saito, Marion Kusche-Gullberg, Ulf Lindahl, and Kazuyuki Sugahara Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7176–7181. Published online 2001 June 5. doi: 10.1073/pnas.131188498.PMCID: PMC34642 Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome Omar A. Ibrahimi, Anna V. Eliseenkova, Alexander N. Plotnikov, Kai Yu, David M. Ornitz, and Moosa Mohammadi Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7182–7187. Published online 2001 June 5. doi: 10.1073/pnas.121183798.PMCID: PMC34643 From the Cover: Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase Gilda Tachedjian, Marianna Orlova, Stefan G. Sarafianos, Edward Arnold, and Stephen P. Goff Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7188–7193. doi: 10.1073/pnas.121055998.PMCID: PMC34644 Complementary intrastrand base pairing during initiation of Herpes simplex virus type 1 DNA replication Alireza Aslani, Bertil Macao, Stina Simonsson, and Per Elias Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7194–7199. doi: 10.1073/pnas.121177198.PMCID: PMC34645 Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor Hui-Kuan Lin, Shuyuan Yeh, Hong-Yo Kang, and Chawnshang Chang Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7200–7205. Published online 2001 June 12. doi: 10.1073/pnas.121173298.PMCID: PMC34646 Identification and characterization of a lysosomal transporter for small neutral amino acids Corinne Sagné, Cendra Agulhon, Philippe Ravassard, Michèle Darmon, Michel Hamon, Salah El Mestikawy, Bruno Gasnier, and Bruno Giros Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7206–7211. Published online 2001 June 5. doi: 10.1073/pnas.121183498.PMCID: PMC34647 Nitric oxide partitioning into mitochondrial membranes and the control of respiration at cytochrome c oxidase Sruti Shiva, Paul S. Brookes, Rakesh P. Patel, Peter G. Anderson, and Victor M. Darley-Usmar Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7212–7217. doi: 10.1073/pnas.131128898.PMCID: PMC34648 Mutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasia Yanwen Chen, Sean S. Molloy, Laurel Thomas, Jay Gambee, Hans Peter Bächinger, Betsy Ferguson, Jonathan Zonana, Gary Thomas, and Nicholas P. Morris Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7218–7223. doi: 10.1073/pnas.131076098.PMCID: PMC34649 A pentacyclic reaction intermediate of riboflavin synthase Boris Illarionov, Wolfgang Eisenreich, and Adelbert Bacher Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7224–7229. Published online 2001 June 12. doi: 10.1073/pnas.131610698.PMCID: PMC34650 Crystal structure of an anticoagulant protein in complex with the Gla domain of factor X Hiroshi Mizuno, Zui Fujimoto, Hideko Atoda, and Takashi Morita Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7230–7234. Published online 2001 June 12. doi: 10.1073/pnas.131179698.PMCID: PMC34651 Biophysics Titration of chaos with added noise Chi-Sang Poon and Mauricio Barahona Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7107–7112. doi: 10.1073/pnas.131173198.PMCID: PMC34630 A quantitative model for membrane fusion based on low-energy intermediates Peter I. Kuzmin, Joshua Zimmerberg, Yuri A. Chizmadzhev, and Fredric S. Cohen Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7235–7240. Published online 2001 June 12. doi: 10.1073/pnas.121191898.PMCID: PMC34652 Use of chimeric proteins to investigate the role of transporter associated with antigen processing (TAP) structural domains in peptide binding and translocation Shikha Arora, Philip Edward Lapinski, and Malini Raghavan Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7241–7246. doi: 10.1073/pnas.131132198.PMCID: PMC34653 Kinetics and mechanism of DNA uptake into the cell nucleus H. Salman, D. Zbaida, Y. Rabin, D. Chatenay, and M. Elbaum Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7247–7252. Published online 2001 June 5. doi: 10.1073/pnas.121067698.PMCID: PMC34654 Simple neural networks for the amplification and utilization of small changes in neuron firing rates Robert K. Adair Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7253–7258. Published online 2001 June 12. doi: 10.1073/pnas.121171598.PMCID: PMC34655 Partial molar volume, surface area, and hydration changes for equilibrium unfolding and formation of aggregation transition state: High-pressure and cosolute studies on recombinant human IFN-γ Jonathan N. Webb, Serena D. Webb, Jeffrey L. Cleland, John F. Carpenter, and Theodore W. Randolph Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7259–7264. Published online 2001 May 29. doi: 10.1073/pnas.131194798.PMCID: PMC34656 From the Cover: A crystallographic map of the transition from B-DNA to A-DNA Jeffrey M. Vargason, Keith Henderson, and P. Shing Ho Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7265–7270. Published online 2001 June 5. doi: 10.1073/pnas.121176898.PMCID: PMC34657 Cell Biology Afipia felis induces uptake by macrophages directly into a nonendocytic compartment Anja Lührmann, Karin Streker, Anja Schüttfort, Justin J. D. Daniels, and Albert Haas Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7271–7276. Published online 2001 June 12. doi: 10.1073/pnas.121190398.PMCID: PMC34658 Thrombin induces the release of the Y-box protein dbpB from mRNA: A mechanism of transcriptional activation Olga I. Stenina, Kristin M. Shaneyfelt, and Paul E. DiCorleto Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7277–7282. Published online 2001 June 5. doi: 10.1073/pnas.121592298.PMCID: PMC34659 Carbon- and nitrogen-quality signaling to translation are mediated by distinct GATA-type transcription factors Finny G. Kuruvilla, Alykhan F. Shamji, and Stuart L. Schreiber Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7283–7288. doi: 10.1073/pnas.121186898.PMCID: PMC34660 From the Cover: Unexpected signals in a system subject to kinetic proofreading Zhao-Jun Liu, Hana Haleem-Smith, Huaxian Chen, and Henry Metzger Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7289–7294. Published online 2001 May 22. doi: 10.1073/pnas.121171998.PMCID: PMC34661 Kinetic proofreading models for cell signaling predict ways to escape kinetic proofreading William S. Hlavacek, Antonio Redondo, Henry Metzger, Carla Wofsy, and Byron Goldstein Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7295–7300. Published online 2001 June 5. doi: 10.1073/pnas.121172298.PMCID: PMC34662 l-Arginine-dependent suppression of apoptosis
in Trypanosoma cruzi: Contribution of the nitric oxide and polyamine pathways Lucía Piacenza, Gonzalo Peluffo, and Rafael Radi Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7301–7306. Published online 2001 June 12. doi: 10.1073/pnas.121520398.PMCID: PMC34663 Corneal collagen fibril structure in three dimensions: Structural insights into fibril assembly, mechanical properties, and tissue organization David F. Holmes, Christopher J. Gilpin, Clair Baldock, Ulrike Ziese, Abraham J. Koster, and Karl E. Kadler Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7307–7312. Published online 2001 June 5. doi: 10.1073/pnas.111150598.PMCID: PMC34664 Protein misfolding and temperature up-shift cause G1 arrest via a common mechanism dependent on heat shock factor in Saccharomyces cerevisiae Eleanor W. Trotter, Lumilla Berenfeld, Sue Ann Krause, Gregory A. Petsko, and Joseph V. Gray Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7313–7318. doi: 10.1073/pnas.121172998.PMCID: PMC34665 Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis Tammy Bowman, Martin A. Broome, Dominic Sinibaldi, Walker Wharton, W. J. Pledger, John M. Sedivy, Rosalyn Irby, Timothy Yeatman, Sara A. Courtneidge, and Richard Jove Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7319–7324. Published online 2001 June 12. doi: 10.1073/pnas.131568898.PMCID: PMC34666 Protein kinase Cdc15 activates the Dbf2-Mob1 kinase complex Angie S. Mah, Joanne Jang, and Raymond J. Deshaies Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7325–7330. Published online 2001 June 12. doi: 10.1073/pnas.141098998.PMCID: PMC34667 Developmental Biology Oxygen deprivation causes suspended animation in the zebrafish embryo Pamela A. Padilla and Mark B. Roth Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7331–7335. Published online 2001 June 12. doi: 10.1073/pnas.131213198.PMCID: PMC34668 Endogenous Msx1 antisense transcript: In vivo and in vitro evidences, structure, and potential involvement in skeleton development in mammals C. Blin-Wakkach, F. Lezot, S. Ghoul-Mazgar, D. Hotton, S. Monteiro, C. Teillaud, L. Pibouin, S. Orestes-Cardoso, P. Papagerakis, M. Macdougall, B. Robert, and A. Berdal Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7336–7341. Published online 2001 June 5. doi: 10.1073/pnas.131497098.PMCID: PMC34669 The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila Nancy Fossett, Sergei G. Tevosian, Kathleen Gajewski, Qian Zhang, Stuart H. Orkin, and Robert A. Schulz Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7342–7347. Published online 2001 June 12. doi: 10.1073/pnas.131215798.PMCID: PMC34670 Timing of metamorphosis and the onset of the negative feedback loop between the thyroid gland and the pituitary is controlled by type II iodothyronine deiodinase in Xenopus laevis Haochu Huang, Liquan Cai, Benjamin F. Remo, and Donald D. Brown Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7348–7353. Published online 2001 June 12. doi: 10.1073/pnas.131198998.PMCID: PMC34671 The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis Chun Li Zhang, Timothy A. McKinsey, and Eric N. Olson Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7354–7359. Published online 2001 June 5. doi: 10.1073/pnas.131198498.PMCID: PMC34672 Nuclear hormone receptor CHR3 is a critical regulator of all four larval molts of the nematode Caenorhabditis elegans Marta Kostrouchova, Michael Krause, Zdenek Kostrouch, and Joseph Edward Rall Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7360–7365. doi: 10.1073/pnas.131171898.PMCID: PMC34673 Ecology Corticosterone levels predict survival probabilities of Galápagos marine iguanas during El Niño events L. Michael Romero and Martin Wikelski Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7366–7370. doi: 10.1073/pnas.131091498.PMCID: PMC34674 Tracking wakes: The nocturnal predatory strategy of piscivorous catfish Kirsten Pohlmann, Frank W. Grasso, and Thomas Breithaupt Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7371–7374. Published online 2001 June 5. doi: 10.1073/pnas.121026298.PMCID: PMC34675 Evolution Evolutionary EST analysis identifies rapidly evolving male reproductive proteins in Drosophila Willie J. Swanson, Andrew G. Clark, Heidi M. Waldrip-Dail, Mariana F. Wolfner, and Charles F. Aquadro Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7375–7379. Published online 2001 June 12. doi: 10.1073/pnas.131568198.PMCID: PMC34676 On the origin of and phylogenetic relationships among
living amphibians Rafael Zardoya and Axel Meyer Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7380–7383. Published online 2001 June 5. doi: 10.1073/pnas.111455498.PMCID: PMC34677 Retroposon analysis of major cetacean lineages: The monophyly of toothed whales and the paraphyly of river dolphins Masato Nikaido, Fumio Matsuno, Healy Hamilton, Robert L. Brownell, Jr., Ying Cao, Wang Ding, Zhu Zuoyan, Andrew M. Shedlock, R. Ewan Fordyce, Masami Hasegawa, and Norihiro Okada Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7384–7389. doi: 10.1073/pnas.121139198.PMCID: PMC34678 Genomic analysis of orthologous mouse and human olfactory receptor loci Robert P. Lane, Tyler Cutforth, Janet Young, Maria Athanasiou, Cynthia Friedman, Lee Rowen, Glen Evans, Richard Axel, Leroy Hood, and Barbara J. Trask Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7390–7395. doi: 10.1073/pnas.131215398.PMCID: PMC34679 Nucleotide sequences provide evidence of genetic exchange among distantly related lineages of Trypanosoma cruzi Carlos A. Machado and Francisco J. Ayala Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7396–7401. doi: 10.1073/pnas.121187198.PMCID: PMC34680 Genetics Genetic and environmental factors modify bovine spongiform encephalopathy incubation period in mice Katerina Manolakou, Jenny Beaton, Irene McConnell, Christine Farquar, Jean Manson, Nicholas D. Hastie, Moira Bruce, and Ian J. Jackson Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7402–7407. Published online 2001 June 12. doi: 10.1073/pnas.121172098.PMCID: PMC34681 Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock Ping Cheng, Yuhong Yang, and Yi Liu Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7408–7413. doi: 10.1073/pnas.121170298.PMCID: PMC34682 From the Cover: A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans Eugene Yujun Xu, Frederick L. Moore, and Renee A. Reijo Pera Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7414–7419. Published online 2001 June 5. doi: 10.1073/pnas.131090498.PMCID: PMC34683 Screening insertion libraries for mutations in many genes simultaneously using DNA microarrays Ramamurthy Mahalingam and Nina Fedoroff Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7420–7425. doi: 10.1073/pnas.121189598.PMCID: PMC34684 Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli Jeffrey O. Blaisdell and Susan S. Wallace Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7426–7430. Published online 2001 June 12. doi: 10.1073/pnas.131077798.PMCID: PMC34685 Immunology Distinct functions and cooperative interaction of the subunits of the transporter associated with antigen processing (TAP) Jaana T. Karttunen, Paul J. Lehner, Soma Sen Gupta, Eric W. Hewitt, and Peter Cresswell Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7431–7436. Published online 2001 May 29. doi: 10.1073/pnas.121180198.PMCID: PMC34686 Positive selection of an MHC class-I restricted TCR in the absence of classical MHC class I molecules Madelon M. Maurice, Dina S. Gould, John Carroll, Yulia Vugmeyster, and Hidde L. Ploegh Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7437–7442. Published online 2001 June 12. doi: 10.1073/pnas.141143298.PMCID: PMC34687 Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models Brian Cao, Yanli Su, Marianne Oskarsson, Ping Zhao, Eric J. Kort, Robert J. Fisher, Ling-Mei Wang, and George F. Vande Woude Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7443–7448. doi: 10.1073/pnas.131200498.PMCID: PMC34688 Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP Michael J. Czar, Ellen N. Kersh, Lilia A. Mijares, Gibson Lanier, Jennifer Lewis, George Yap, Amy Chen, Alan Sher, Colin S. Duckett, Rafi Ahmed, and Pamela L. Schwartzberg Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7449–7454. Published online 2001 June 12. doi: 10.1073/pnas.131193098.PMCID: PMC34689 Clonable progenitors committed to the T lymphocyte lineage in the mouse bone marrow; use of an extrathymic pathway Sussan Dejbakhsh-Jones, Marcos E. García-Ojeda, Devavani Chatterjea-Matthes, Defu Zeng, and Samuel Strober Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7455–7460. Published online 2001 June 5. doi: 10.1073/pnas.131559798.PMCID: PMC34690 INAUGURAL ARTICLE by a Recently Elected Academy Member: How the immune system works to protect the host from infection: A personal view Charles A. Janeway, Jr. Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7461–7468. Published online 2001 June 5. doi: 10.1073/pnas.131202998.PMCID: PMC34691 Medical Sciences Conditional and targeted overexpression of vascular chymase causes hypertension in transgenic mice Haisong Ju, Robert Gros, Xiaomang You, Sarah Tsang, Mansoor Husain, and Marlene Rabinovitch Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7469–7474. doi: 10.1073/pnas.131147598.PMCID: PMC34692 Evidence for a circulating islet cell growth factor in insulin-resistant states Sarah N. Flier, Rohit N. Kulkarni, and C. Ronald Kahn Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7475–7480. Published online 2001 June 12. doi: 10.1073/pnas.131192998.PMCID: PMC34693 Excessive tumor-elaborated VEGF and its neutralization define a lethal paraneoplastic syndrome Alex K. Wong, Myra Alfert, Diego H. Castrillon, Qiong Shen, Jocelyn Holash, George D. Yancopoulos, and Lynda Chin Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7481–7486. Published online 2001 June 12. doi: 10.1073/pnas.121192298.PMCID: PMC34694 γ-Secretase inhibitors repress thymocyte development Brandon K. Hadland, Nancy R. Manley, Dong-ming Su, Gregory D. Longmore, Chad L. Moore, Michael S. Wolfe, Eric H. Schroeter, and Raphael Kopan Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7487–7491. doi: 10.1073/pnas.131202798.PMCID: PMC34695 CML66, a broadly immunogenic tumor antigen, elicits a humoral immune response associated with remission of chronic myelogenous leukemia Xiao-Feng Yang, Catherine J. Wu, Stephen McLaughlin, Antoinette Chillemi, Kathy S. Wang, Christine Canning, Edwin P. Alyea, Philip Kantoff, Robert J. Soiffer, Glenn Dranoff, and Jerome Ritz Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7492–7497. doi: 10.1073/pnas.131590998.PMCID: PMC34696 Targeted ablation of the 25-hydroxyvitamin D 1α-hydroxylase enzyme: Evidence for skeletal, reproductive, and immune dysfunction Dibyendu K. Panda, Dengshun Miao, Michel L. Tremblay, Jacinthe Sirois, Riaz Farookhi, Geoffrey N. Hendy, and David Goltzman Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7498–7503. doi: 10.1073/pnas.131029498.PMCID: PMC34697 The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis Koen Dreijerink, Eleonora Braga, Igor Kuzmin, Laura Geil, Fuh-Mei Duh, Debora Angeloni, Berton Zbar, Michael I. Lerman, Eric J. Stanbridge, John D. Minna, Alexei Protopopov, Jingfeng Li, Vladimir Kashuba, George Klein, and Eugene R. Zabarovsky Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7504–7509. Published online 2001 June 5. doi: 10.1073/pnas.131216298.PMCID: PMC34698 Omega 3 but not omega 6 fatty acids inhibit AP-1 activity and cell transformation in JB6 cells Guangming Liu, Douglas M. Bibus, Ann M. Bode, Wei-Ya Ma, Ralph T. Holman, and Zigang Dong Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7510–7515. doi: 10.1073/pnas.131195198.PMCID: PMC34699 Ullrich scleroatonic muscular dystrophy is caused by recessive mutations in collagen type VI Olga Camacho Vanegas, Enrico Bertini, Rui-Zhu Zhang, Stefania Petrini, Claudia Minosse, Patrizia Sabatelli, Betti Giusti, Mon-Li Chu, and Guglielmina Pepe Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7516–7521. Published online 2001 May 29. doi: 10.1073/pnas.121027598.PMCID: PMC34700 Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance Jason K. Kim, Jonathan J. Fillmore, Yan Chen, Chunli Yu, Irene K. Moore, Marc Pypaert, E. Peer Lutz, Yuko Kako, Wanda Velez-Carrasco, Ira J. Goldberg, Jan L. Breslow, and Gerald I. Shulman Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7522–7527. Published online 2001 June 5. doi: 10.1073/pnas.121164498.PMCID: PMC34701 In vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapy Doron Shabat, Holger N. Lode, Ursula Pertl, Ralph A. Reisfeld, Christoph Rader, Richard A. Lerner, and Carlos F. Barbas, III Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7528–7533. Published online 2001 June 12. doi: 10.1073/pnas.131187998.PMCID: PMC34702 Microbiology Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding α-crystallin David R. Sherman, Martin Voskuil, Dirk Schnappinger, Reiling Liao, Maria I. Harrell, and Gary K. Schoolnik Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7534–7539. doi: 10.1073/pnas.121172498.PMCID: PMC34703 Light regulation of type IV pilus-dependent motility by chemosensor-like elements in Synechocystis PCC6803 Devaki Bhaya, Akiko Takahashi, and Arthur R. Grossman Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7540–7545. Published online 2001 June 12. doi: 10.1073/pnas.131201098.PMCID: PMC34704 A novel application of gene arrays: Escherichia coli array provides insight into the biology of the obligate endosymbiont of tsetse flies Leyla Akman and Serap Aksoy Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7546–7551. Published online 2001 June 12. doi: 10.1073/pnas.131057498.PMCID: PMC34705 Multilocus analysis of extracellular putative virulence proteins made by group A Streptococcus: Population genetics, human serologic response, and gene transcription Sean D. Reid, Nicole M. Green, Julie K. Buss, Benfang Lei, and James M. Musser Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7552–7557. doi: 10.1073/pnas.121188598.PMCID: PMC34706 Neurobiology Dopamine receptor regulating factor, DRRF: A zinc finger transcription factor Cheol Kyu Hwang, Ursula M. D'Souza, Amelia J. Eisch, Shunsuke Yajima, Claas-Hinrich Lammers, Young Yang, Sang-Hyeon Lee, Yong-Man Kim, Eric J. Nestler, and M. Maral Mouradian Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7558–7563. Published online 2001 June 5. doi: 10.1073/pnas.121635798.PMCID: PMC34707 Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R Andreas W. Sailer, Hideki Sano, Zhizhen Zeng, Terrence P. McDonald, Jie Pan, Sheng-Shung Pong, Scott D. Feighner, Carina P. Tan, Takehiro Fukami, Hisashi Iwaasa, Donna L. Hreniuk, Nancy R. Morin, Sharon J. Sadowski, Makoto Ito, Masahiko Ito, Alka Bansal, Betty Ky, David J. Figueroa, Qingping Jiang, Christopher P. Austin, Douglas J. MacNeil, Akane Ishihara, Masaki Ihara, Akio Kanatani, Lex H. T. Van der Ploeg, Andrew D. Howard, and Qingyun Liu Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7564–7569. Published online 2001 June 12. doi: 10.1073/pnas.121170598.PMCID: PMC34708 Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor K. Lewis, C. Li, M. H. Perrin, A. Blount, K. Kunitake, C. Donaldson, J. Vaughan, T. M. Reyes, J. Gulyas, W. Fischer, L. Bilezikjian, J. Rivier, P. E. Sawchenko, and W. W. Vale Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7570–7575. doi: 10.1073/pnas.121165198.PMCID: PMC34709 Identification and characterization of a melanin-concentrating hormone receptor Songzhu An, Gene Cutler, Jack Jiagang Zhao, Shu-Gui Huang, Hui Tian, Wanbo Li, Lingming Liang, Miki Rich, Amy Bakleh, Juan Du, Jin-Long Chen, and Kang Dai Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7576–7581. doi: 10.1073/pnas.131200698.PMCID: PMC34710 Synaptic sprouting increases the uptake capacities of motoneurons in amyotrophic lateral sclerosis mice Stéphanie Millecamps, Delphine Nicolle, Irène Ceballos-Picot, Jacques Mallet, and Martine Barkats Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7582–7587. Published online 2001 June 12. doi: 10.1073/pnas.131031098.PMCID: PMC34711 Evolution and divergence of sodium channel genes in vertebrates Gregory F. Lopreato, Ying Lu, Amber Southwell, Nigel S. Atkinson, David M. Hillis, Thomas P. Wilcox, and Harold H. Zakon Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7588–7592. doi: 10.1073/pnas.131171798.PMCID: PMC34712 Effects of anesthesia on functional activation of cerebral blood flow and metabolism Yasuaki Nakao, Yoshiaki Itoh, Tang-Yong Kuang, Michelle Cook, Jane Jehle, and Louis Sokoloff Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7593–7598. Published online 2001 June 5. doi: 10.1073/pnas.121179898.PMCID: PMC34713 Pharmacology Antillatoxin is a marine cyanobacterial toxin that potently activates voltage-gated sodium channels W. I. Li, F. W. Berman, T. Okino, F. Yokokawa, T. Shioiri, W. H. Gerwick, and T. F. Murray Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7599–7604. doi: 10.1073/pnas.121085898.PMCID: PMC34714 Phenserine regulates translation of β-amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development Karen T. Y. Shaw, Tadanobu Utsuki, Jack Rogers, Qian-Sheng Yu, Kumar Sambamurti, Arnold Brossi, Yuan-Wen Ge, Debomoy K. Lahiri, and Nigel H. Greig Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7605–7610. Published online 2001 June 12. doi: 10.1073/pnas.131152998.PMCID: PMC34715 Grafts of adenosine-releasing cells suppress seizures in kindling epilepsy Alexander Huber, Vivianne Padrun, Nicole Déglon, Patrick Aebischer, Hanns Möhler, and Detlev Boison Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7611–7616. Published online 2001 June 12. doi: 10.1073/pnas.131102898.PMCID: PMC34716 Heteromeric association creates a P2Y-like adenosine receptor Kazuaki Yoshioka, Osamu Saitoh, and Hiroyasu Nakata Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7617–7622. Published online 2001 June 5. doi: 10.1073/pnas.121587098.PMCID: PMC34717 Physiology Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channels Antonio J. Carrasco, Petras P. Dzeja, Alexey E. Alekseev, Darko Pucar, Leonid V. Zingman, M. Roselle Abraham, Denice Hodgson, Martin Bienengraeber, Michel Puceat, Edwin Janssen, Be Wieringa, and Andre Terzic Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7623–7628. Published online 2001 June 5. doi: 10.1073/pnas.121038198.PMCID: PMC34718 Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin Gitta Neufang, Gerhard Fürstenberger, Markus Heidt, Friedrich Marks, and Karin Müller-Decker Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7629–7634. Published online 2001 May 29. doi: 10.1073/pnas.121574098.PMCID: PMC34719 Plant Biology Transcription factor RF2a alters expression of the rice tungro bacilliform virus promoter in transgenic tobacco plants Silvana Petruccelli, Shunhong Dai, Rosa Carcamo, Yanhai Yin, Shouyi Chen, and Roger N. Beachy Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7635–7640. Published online 2001 June 5. doi: 10.1073/pnas.121186398.PMCID: PMC34720 Social Sciences Anthropology Thirty years on the “Broad Spectrum Revolution” and paleolithic demography Mary C. Stiner Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 6993–6996. Published online 2001 June 5. doi: 10.1073/pnas.121176198.PMCID: PMC34611 Ornaments of the earliest Upper Paleolithic: New insights from the Levant Steven L. Kuhn, Mary C. Stiner, David S. Reese, and Erksin Güleç Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7641–7646. Published online 2001 June 5. doi: 10.1073/pnas.121590798.PMCID: PMC34721 Corrections Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7647. PMCID: PMC55962 Corrects: Lu Tian, et al. Blocking histone deacetylation in Arabidopsis
induces pleiotropic effects on plant gene regulation and development. Proc Natl Acad Sci U S A. 2001 January 2; 98(1): 200–205. Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7647. PMCID: PMC55963 Corrects: T Kakutani, et al. Developmental abnormalities and epimutations associated with DNA hypomethylation mutations. Proc Natl Acad Sci U S A. 1996 October 29; 93(22): 12406–12411. Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7647. Published online 2001 June 12. PMCID: PMC55964 Corrects: Liyanage P. Perera, et al. Comparative assessment of virulence of recombinant vaccinia
viruses expressing IL-2 and IL-15 in immunodeficient mice. Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5146–5151. Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7647. Published online 2001 June 12. PMCID: PMC55965 Corrects: Alvin Berger, et al. Anandamide and diet: Inclusion of dietary arachidonate and
docosahexaenoate leads to increased brain levels of the corresponding
N-acylethanolamines in piglets. Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6402–6406. Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7647. Published online 2001 June 12. PMCID: PMC55966 Corrects: C. Ronald Geyer, et al. “Mutagenesis” by peptide aptamers identifies genetic network members and pathway connections. Proc Natl Acad Sci U S A. 1999 July 20; 96(15): 8567–8572. Proc Natl Acad Sci U S A. 2001 June 19; 98(13): 7647. PMCID: PMC55967 Corrects: Baljit S. Khakh, et al. Activation-dependent changes in receptor distribution and
dendritic morphology in hippocampal neurons expressing
P2X2-green fluorescent protein receptors. Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5288–5293. |