| | This journal provides immediate access to some articles. Commentary Teaching bacteria a new language Yoram Gerchman and Ron Weiss PMCID: PMC356931 Physical Sciences Applied Physical Sciences Functional analysis of each blue light receptor, cry1, cry2, phot1, and phot2, by using combinatorial multiple mutants in Arabidopsis Maki Ohgishi, Kensuke Saji, Kiyotaka Okada, and Tatsuya Sakai PMCID: PMC356932 Membrane and acto-myosin tension promote clustering of adhesion proteins H. Delanoë-Ayari, R. Al Kurdi, M. Vallade, D. Gulino-Debrac, and D. Riveline PMCID: PMC356933 Biological Sciences Agricultural Sciences Engineering Escherichia coli for efficient conversion of glucose to pyruvate T. B. Causey, K. T. Shanmugam, L. P. Yomano, and L. O. Ingram PMCID: PMC356934 Biochemistry Identification of biochemical adaptations in hyper- or hypocontractile hearts from phospholamban mutant mice by expression proteomics Yan Pan, Thomas Kislinger, Anthony O. Gramolini, Elena Zvaritch, Evangelia G. Kranias, David H. MacLennan, and Andrew Emili PMCID: PMC356935 Probing the antibody-catalyzed water-oxidation pathway at atomic resolution Xueyong Zhu, Paul Wentworth, Jr., Anita D. Wentworth, Albert Eschenmoser, Richard A. Lerner, and Ian A. Wilson PMCID: PMC356936 Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells Huib Ovaa, Benedikt M. Kessler, Ulrika Rolén, Paul J. Galardy, Hidde L. Ploegh, and Maria G. Masucci PMCID: PMC356937 Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo Jianyuan Luo, Muyang Li, Yi Tang, Monika Laszkowska, Robert G. Roeder, and Wei Gu PMCID: PMC356938 Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase Hong Ling, Jane M. Sayer, Brian S. Plosky, Haruhiko Yagi, François Boudsocq, Roger Woodgate, Donald M. Jerina, and Wei Yang PMCID: PMC356939 Differential recruitment of nuclear receptor coactivators may determine alternative RNA splice site choice in target genes Didier Auboeuf, Dennis H. Dowhan, Yun Kyoung Kang, Kimberly Larkin, Jae Woon Lee, Susan M. Berget, and Bert W. O'Malley PMCID: PMC356940 Heterodimeric interactions among the 1-amino-cyclopropane-1-carboxylate synthase polypeptides encoded by the Arabidopsis gene family Atsunari Tsuchisaka and Athanasios Theologis PMCID: PMC356941 Functional bacteriorhodopsin is efficiently solubilized and delivered to membranes by the chaperonin GroEL John Deaton, Jingchuan Sun, Andreas Holzenburg, Douglas K. Struck, Joel Berry, and Ry Young PMCID: PMC356942 The elongation of yeast prion fibers involves separable steps of association and conversion Thomas Scheibel, Jesse Bloom, and Susan L. Lindquist PMCID: PMC356943 Biophysics From conversion to aggregation: Protofibril formation of the prion protein Mari L. DeMarco and Valerie Daggett PMCID: PMC356944 From the Cover:
Design of artificial cell–cell communication using gene and metabolic networks Thomas Bulter, Sun-Gu Lee, Wilson WaiChun Wong, Eileen Fung, Michael R. Connor, and James C. Liao PMCID: PMC356945 Protein structure prediction for the male-specific region of the human Y chromosome Krzysztof Ginalski, Leszek Rychlewski, David Baker, and Nick V. Grishin PMCID: PMC356946 Cell Biology PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells Ming-Zhi Zhang, Weiyi Mai, Cunxi Li, Sae-youll Cho, Chuanming Hao, Gilbert Moeckel, Runxiang Zhao, Ingyu Kim, Jikui Wang, Huaqi Xiong, Hong Wang, Yasunori Sato, Yizhong Wu, Yasuni Nakanuma, Marusia Lilova, York Pei, Raymond C. Harris, Song Li, Robert J. Coffey, Le Sun, Dianqing Wu, Xing-Zhen Chen, Matthew D. Breyer, Zhizhuang Joe Zhao, James A. McKanna, and Guanqing Wu PMCID: PMC356947 Cells adapted to high NaCl have many DNA breaks and impaired DNA repair both in cell culture and in vivo Natalia I. Dmitrieva, Qi Cai, and Maurice B. Burg PMCID: PMC356948 Agonist-induced Ca2+ entry determined by inositol 1,4,5-trisphosphate recognition Damian B. van Rossum, Randen L. Patterson, Kirill Kiselyov, Darren Boehning, Roxanne K. Barrow, Donald L. Gill, and Solomon H. Snyder PMCID: PMC356949 RACK1 binds to inositol 1,4,5-trisphosphate receptors and mediates Ca2+ release Randen L. Patterson, Damian B. van Rossum, Roxanne K. Barrow, and Solomon H. Snyder PMCID: PMC356950 Activation of integrin β-subunit I-like domains by one-turn C-terminal α-helix deletions Wei Yang, Motomu Shimaoka, JianFeng Chen, and Timothy A. Springer PMCID: PMC356951 The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator Fajun Yang, Rosalie DeBeaumont, Sharleen Zhou, and Anders M. Näär PMCID: PMC356952 The Shc adaptor protein is critical for VEGF induction by Met/HGF and ErbB2 receptors and for early onset of tumor angiogenesis Caroline Saucier, Hanane Khoury, Ka-Man Venus Lai, Pascal Peschard, David Dankort, Monica A. Naujokas, Jocelyn Holash, George D. Yancopoulos, William J. Muller, Tony Pawson, and Morag Park PMCID: PMC356953 The Bik BH3-only protein is induced in estrogen-starved and antiestrogen-exposed breast cancer cells and provokes apoptosis Jingyung Hur, Jessica Chesnes, Kathryn R. Coser, Roseanna S. Lee, Peter Geck, Kurt J. Isselbacher, and Toshi Shioda PMCID: PMC356954 The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations Sharon Cantor, Ronny Drapkin, Fan Zhang, Yafang Lin, Juliana Han, Sushmita Pamidi, and David M. Livingston PMCID: PMC356955 Developmental Biology Reactivation of developmental programs: The cAMP-response element-binding protein pathway is involved in hydra head regeneration Kostas Kaloulis, Simona Chera, Monika Hassel, Dominique Gauchat, and Brigitte Galliot PMCID: PMC356956 Ecology High genetic variability and low local diversity in a population of arbuscular mycorrhizal fungi Alexander M. Koch, Gerrit Kuhn, Pierre Fontanillas, Luca Fumagalli, Jérôme Goudet, and Ian R. Sanders PMCID: PMC356957 Association between climate variability and malaria epidemics in the East African highlands Guofa Zhou, Noboru Minakawa, Andrew K. Githeko, and Guiyun Yan PMCID: PMC356958 Evolution From the Cover:
Stabilizing selection on genomic divergence in a wild fish population Bryan D. Neff PMCID: PMC356959 Genetics Exceptional conservation of horse–human gene order on X chromosome revealed by high-resolution radiation hybrid mapping Terje Raudsepp, Eun-Joon Lee, Srinivas R. Kata, Candice Brinkmeyer, James R. Mickelson, Loren C. Skow, James E. Womack, and Bhanu P. Chowdhary PMCID: PMC356960 Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression Cristina López-Rodríguez, Christopher L. Antos, John M. Shelton, James A. Richardson, Fangming Lin, Tatiana I. Novobrantseva, Roderick T. Bronson, Peter Igarashi, Anjana Rao, and Eric N. Olson PMCID: PMC356961 Genetic and functional confirmation of the causality of the DGAT1 K232A quantitative trait nucleotide in affecting milk yield and composition Bernard Grisart, Frédéric Farnir, Latifa Karim, Nadine Cambisano, Jong-Joo Kim, Alex Kvasz, Myriam Mni, Patricia Simon, Jean-Marie Frère, Wouter Coppieters, and Michel Georges PMCID: PMC356962 Evolutionary comparisons suggest many novel cAMP response protein binding sites in Escherichia coli C. T. Brown and C. G. Callan, Jr. PMCID: PMC356963 Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells Sean Rooney, JoAnn Sekiguchi, Scott Whitlow, Mark Eckersdorff, John P. Manis, Charles Lee, David O. Ferguson, and Frederick W. Alt PMCID: PMC356964 Immunology Negative regulation of IFN-α/β signaling by IFN regulatory factor 2 for homeostatic development of dendritic cells Kenya Honda, Tatsuaki Mizutani, and Tadatsugu Taniguchi PMCID: PMC356965 Interplay between antibacterial effectors: A macrophage antimicrobial peptide impairs intracellular Salmonella replication Carrie M. Rosenberger, Richard L. Gallo, and B. Brett Finlay PMCID: PMC356966 Multiple sclerosis: Brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood Christian Skulina, Stephan Schmidt, Klaus Dornmair, Holger Babbe, Axel Roers, Klaus Rajewsky, Hartmut Wekerle, Reinhard Hohlfeld, and Norbert Goebels PMCID: PMC356967 The precursor form of IL-1α is an intracrine proinflammatory activator of transcription Ariel Werman, Rachel Werman-Venkert, Rosalyn White, Jae-Kwon Lee, Batsheva Werman, Yakov Krelin, Elena Voronov, Charles A. Dinarello, and Ron N. Apte PMCID: PMC356968 From the Cover:
Long-range histone acetylation of the Ifng gene is an essential feature of T cell differentiation Weisong Zhou, Shaojing Chang, and Thomas M. Aune PMCID: PMC356969 Analysis of intergenic transcription in the human IL-4/IL-13 gene cluster David F. Rogan, David J. Cousins, Samantha Santangelo, Panayiotis A. Ioannou, Michael Antoniou, Tak H. Lee, and Dontcho Z. Staynov PMCID: PMC356970 Medical Sciences IκB-kinaseβ-dependent NF-κB activation provides radioprotection to the intestinal epithelium Laurence J. Egan, Lars Eckmann, Florian R. Greten, Sungwon Chae, Zhi-Wei Li, Gennett M. Myhre, Sylvie Robine, Michael Karin, and Martin F. Kagnoff PMCID: PMC356971 Extrapancreatic insulin-producing cells in multiple organs in diabetes Hideto Kojima, Mineko Fujimiya, Kazuhiro Matsumura, Tamio Nakahara, Manami Hara, and Lawrence Chan PMCID: PMC356972 Relationship between the frequency of HIV-specific CD8+ T cells and the level of CD38+CD8+ T cells in untreated HIV-infected individuals Tae-Wook Chun, J. Shawn Justement, Christina Sanford, Claire W. Hallahan, Marie A. Planta, Mona Loutfy, Shyam Kottilil, Susan Moir, Colin Kovacs, and Anthony S. Fauci PMCID: PMC356973 Bilirubin protects astrocytes from its own toxicity by inducing up-regulation and translocation of multidrug resistance-associated protein 1 (Mrp1) Florinda Gennuso, Cristina Fernetti, Cataldo Tirolo, Nuccio Testa, Francesca L'Episcopo, Salvo Caniglia, Maria Concetta Morale, J. Donald Ostrow, Lorella Pascolo, Claudio Tiribelli, and Bianca Marchetti PMCID: PMC356974 Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis Ebba Bråkenhielm, Niina Veitonmäki, Renhai Cao, Shinji Kihara, Yuji Matsuzawa, Boris Zhivotovsky, Tohru Funahashi, and Yihai Cao PMCID: PMC356975 Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta Anthony G. Passerini, Denise C. Polacek, Congzhu Shi, Nadeene M. Francesco, Elisabetta Manduchi, Gregory R. Grant, William F. Pritchard, Steven Powell, Gary Y. Chang, Christian J. Stoeckert, Jr., and Peter F. Davies PMCID: PMC356976 Mapping a locus for susceptibility to HIV-1-associated nephropathy to mouse chromosome 3 Ali G. Gharavi, Tariq Ahmad, Robert D. Wong, Roozbeh Hooshyar, Janene Vaughn, Sarah Oller, Rachelle Z. Frankel, Leslie A. Bruggeman, Vivette D. D'Agati, Paul E. Klotman, and Richard P. Lifton PMCID: PMC356977 An anti-CD45RO immunotoxin kills HIV-latently infected cells from individuals on HAART with little effect on CD8 memory J. Saavedra-Lozano, Y. Cao, J. Callison, R. Sarode, D. Sodora, J. Edgar, J. Hatfield, L. Picker, D. Peterson, O. Ramilo, and E. S. Vitetta PMCID: PMC356978 Zinc-α2-glycoprotein, a lipid mobilizing factor, is expressed in adipocytes and is up-regulated in mice with cancer cachexia Chen Bing, Yi Bao, John Jenkins, Paul Sanders, Monia Manieri, Saverio Cinti, Michael J. Tisdale, and Paul Trayhurn PMCID: PMC356979 Microbiology Genetic and biophysical studies of diphtheria toxin repressor (DtxR) and the hyperactive mutant DtxR(E175K) support a multistep model of activation John F. Love, Johanna C. vanderSpek, Vedrana Marin, Luis Guerrero, Timothy M. Logan, and John R. Murphy PMCID: PMC356980 The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533 R. David Pridmore, Bernard Berger, Frank Desiere, David Vilanova, Caroline Barretto, Anne-Cecile Pittet, Marie-Camille Zwahlen, Martine Rouvet, Eric Altermann, Rodolphe Barrangou, Beat Mollet, Annick Mercenier, Todd Klaenhammer, Fabrizio Arigoni, and Mark A. Schell PMCID: PMC356981 Polymorphism in the Plasmodium falciparum erythrocyte-binding ligand JESEBL/EBA-181 alters its receptor specificity D. C. Ghislaine Mayer, Jian-Bing Mu, Osamu Kaneko, Junhui Duan, Xin-zhuan Su, and Louis H. Miller PMCID: PMC356982 The Vibrio cholerae chitin utilization program Karin L. Meibom, Xibing B. Li, Alex T. Nielsen, Cheng-Yen Wu, Saul Roseman, and Gary K. Schoolnik PMCID: PMC356983 The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes Jianxin He, Regina L. Baldini, Eric Déziel, Maude Saucier, Qunhao Zhang, Nicole T. Liberati, Daniel Lee, Jonathan Urbach, Howard M. Goodman, and Laurence G. Rahme PMCID: PMC356984 Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association Jianhua Sui, Wenhui Li, Akikazu Murakami, Azaibi Tamin, Leslie J. Matthews, Swee Kee Wong, Michael J. Moore, Aimee St. Clair Tallarico, Mobolaji Olurinde, Hyeryun Choe, Larry J. Anderson, William J. Bellini, Michael Farzan, and Wayne A. Marasco PMCID: PMC356985 Characterization of severe acute respiratory syndrome coronavirus genomes in Taiwan: Molecular epidemiology and genome evolution Shiou-Hwei Yeh, Hurng-Yi Wang, Ching-Yi Tsai, Chuan-Liang Kao, Jyh-Yuan Yang, Hwan-Wun Liu, Ih-Jen Su, Shih-Feng Tsai, Ding-Shinn Chen, Pei-Jer Chen, and the National Taiwan University SARS Research Team PMCID: PMC356986 Neuroscience Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage Angela Ho and Thomas C. Südhof PMCID: PMC356987 Unexpected Ca2+-binding properties of synaptotagmin 9 Ok-Ho Shin, Anton Maximov, Byung Kook Lim, Josep Rizo, and Thomas C. Südhof PMCID: PMC356988 Topographic specificity of functional connections from hippocampal CA3 to CA1 Iman H. Brivanlou, Jami L. M. Dantzker, Charles F. Stevens, and Edward M. Callaway PMCID: PMC356989 Optical imaging of visually evoked responses in prosimian primates reveals conserved features of the middle temporal visual area Xiangmin Xu, Christine E. Collins, Peter M. Kaskan, Ilya Khaytin, Jon H. Kaas, and Vivien A. Casagrande PMCID: PMC356990 From the Cover:
Mutation of the zebrafish choroideremia gene encoding Rab escort protein 1 devastates hair cells Catherine J. Starr, James A. Kappler, Dylan K. Chan, Richard Kollmar, and A. J. Hudspeth PMCID: PMC356991 Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner Ofer Yizhar, Ulf Matti, Rely Melamed, Yamit Hagalili, Dieter Bruns, Jens Rettig, and Uri Ashery PMCID: PMC356992 The human olfactory receptor gene family Bettina Malnic, Paul A. Godfrey, and Linda B. Buck PMCID: PMC356993 Prostaglandin E2-increased thermosensitivity of anterior hypothalamic neurons is associated with depressed inhibition Iustin V. Tabarean, M. Margarita Behrens, Tamas Bartfai, and Henri Korn PMCID: PMC356994 Potentiation of NMDA receptor currents by dopamine D1 receptors in prefrontal cortex Guojun Chen, Paul Greengard, and Zhen Yan PMCID: PMC356995 Radixin is a constituent of stereocilia in hair cells F. Pataky, R. Pironkova, and A. J. Hudspeth PMCID: PMC356996 Postsynaptic N-methyl-d-aspartate receptor function requires α-neurexins Gunnar Kattenstroth, Evangelia Tantalaki, Thomas C. Südhof, Kurt Gottmann, and Markus Missler PMCID: PMC356997 Identification of a developmentally regulated striatum-enriched zinc-finger gene, Nolz-1, in the mammalian brain Chiung-Wen Chang, Chi-Wei Tsai, Hsiao-Fang Wang, Hsiu-Chao Tsai, Huei-Ying Chen, Ting-Fen Tsai, Hiroshi Takahashi, Hui-Yun Li, Ming-Ji Fann, Chu-Wen Yang, Yoshihide Hayashizaki, Tetsuichiro Saito, and Fu-Chin Liu PMCID: PMC356998 Pharmacology S-nitrosylation of endothelial nitric oxide synthase is associated with monomerization and decreased enzyme activity Kandasam Ravi, Lisa A. Brennan, Snezana Levic, Patrick A. Ross, and Stephen M. Black PMCID: PMC356999 Physiology Regulation of canonical transient receptor potential isoform 3 (TRPC3) channel by protein kinase G Hiu-Yee Kwan, Yu Huang, and Xiaoqiang Yao PMCID: PMC357000 Carbon monoxide mediates vasoactive intestinal polypeptide-associated nonadrenergic/noncholinergic neurotransmission Crystal C. Watkins, Darren Boehning, Adam I. Kaplin, Mahil Rao, Christopher D. Ferris, and Solomon H. Snyder PMCID: PMC357001 Nongenomic stimulation of vacuolar H+-ATPases in intercalated renal tubule cells by aldosterone Christian Winter, Nicole Schulz, Gerhard Giebisch, John P. Geibel, and Carsten A. Wagner PMCID: PMC357002 Plant Biology Thioredoxin links redox to the regulation of fundamental processes of plant mitochondria Yves Balmer, William H. Vensel, Charlene K. Tanaka, William J. Hurkman, Eric Gelhaye, Nicolas Rouhier, Jean-Pierre Jacquot, Wanda Manieri, Peter Schürmann, Michel Droux, and Bob B. Buchanan PMCID: PMC357003 |
