Home
Search
Study Topics
Glossary
|
|
|
|
|
|
Sponsors and Collaborators: |
Alberta Cancer Board ACB Palliative Care Research Initiative |
---|---|
Information provided by: | Alberta Cancer Board |
ClinicalTrials.gov Identifier: | NCT00125684 |
Patients will participate in two arms of the trial, one in which morphine will be administered transdermally, and, after a 3 day wash out period, one in which morphine will be administered subcutaneously.
Condition | Intervention | Phase |
---|---|---|
Cancer Pain |
Drug: morphine |
Phase I |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Bio-availability Study |
Official Title: | Bioavailability and Effectiveness of Transdermally Administered Morphine |
Estimated Enrollment: | 6 |
Study Start Date: | July 2003 |
Study Completion Date: | July 2008 |
Primary Completion Date: | July 2007 (Final data collection date for primary outcome measure) |
Patients will participate in two arms of the trial, one in which morphine will be administered transdermally, and, after a 3 day wash out period, one in which morphine will be administered subcutaneously. Blood draws will be done after both dosing methods in order to compare blood levels of morphine by the different routes.
Ages Eligible for Study: | 18 Years to 65 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Canada, Alberta | |
Tom Baker Cancer Centre | |
Calgary, Alberta, Canada, T2N 4N2 |
Principal Investigator: | Neil Hagen | Alberta Cancerboard |
Study ID Numbers: | 10181 |
Study First Received: | July 29, 2005 |
Last Updated: | August 13, 2008 |
ClinicalTrials.gov Identifier: | NCT00125684 |
Health Authority: | Canada: Health Canada |
transdermal morphine cancer pain bioavailability |
pharmacokinetics cancer related pain stable baseline pain currently taking opioids |
Morphine Pain |
Sensory System Agents Therapeutic Uses Physiological Effects of Drugs Central Nervous System Depressants Narcotics |
Peripheral Nervous System Agents Analgesics Central Nervous System Agents Pharmacologic Actions Analgesics, Opioid |