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Agent Name d-Limonene
CAS Number 5989-27-5
Formula C10-H16
Major Category Solvents
Synonyms (+)-(4R)-Limonene; (+)-4-Isopropenyl-1-methylcyclohexene; (+)-Dipentene; (+)-Limonene; (+)-R-Limonene; (+)-alpha-Limonene; (+)-p-Mentha-1,8-diene; (4R)-(+)-Limonene; (4R)-Limonene; (R)-(+)-Limonene; (R)-(+)-p-Mentha-1,8-diene; (R)-1-Methyl-4-(1-methylethenyl)cyclohexene; (R)-4-Isopropenyl-1-methyl-1-cyclohexene; (R)-Limonene; (R)-p-Mentha-1,8-diene; 1-Methyl-4-(1-methylethenyl)cyclohexene, (R)-; Biogenic SE 374; Carvene; Citrene; D-(+)-Limonene; EC 7;Glidesafe; Glidsafe; Kautschiin; Limonene, (+)-; Refchole; d-(+)-Limonene; d-Limonene; d-Limonene (natural); d-Limoneno [Spanish]; d-p-Mentha-1,8-diene; p-Mentha-1,8-diene, (R)-(+)-; [ChemIDplus] UN1993; UN2319; UN2052
Category Aliphatics, Unsaturated
Description Liquid; [HSDB]
Sources/Uses Used in flavorings, fragrances, cosmetics, as a solvent, wetting agent, the manufacture of resins, insecticides, insect repellants, and animal repellants; [HSDB]
Comments d-Limonene is a liquid with a pleasant lemon-like odor. It is used as a solvent to replace chlorinated hydrocarbons and other more volatile and toxic organic solvents. It readily oxidizes when in contact with air. The oxidized form of d-limonene is a known skin sensitizer. [HSDB] The racemic mixture of d-limonene and l-limonene is called dipentene (138-86-3). [Kanerva, p. 1147] A skin and eye irritant that may cause skin sensitization; [ICSC]
Reference Link Contact allergy to oxidized d-limonene among dermatitis patients
Exposure Assessment
Skin Designation (ACGIH) Not evaluated
MAK 20 ppm
Vapor Pressure 1.98 mm Hg
Explanatory Notes Flash point = 48 deg C;
Reference Link International Chemical Safety Cards (WHO/IPCS/ILO)
Flammability (NFPA) 2: high ambient temperature required
Adverse Effects
Skin Sensitizer Yes
IARC Carcinogen Not Classifiable
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: (D)-LIMONENE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:
Activities Activities with risk of exposure:





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Last updated: January, 2009