Skip Navigation

HazMap: Occupational Exposure to Hazardous Agents
HazMap Home SIS Home NLM Home

as Search Agents Search Diseases Search Jobs Full Text Search


Haz-Map Home on-tab Custom Search on-tab Help on-tab Web Glossary on-tab Reference on-tab
left corner Browse Haz-Map
right corner
Agent Name Methyl vinyl ketone
Alternative Name 3-Buten-2-one
CAS Number 78-94-4
Formula C4-H6-O
Major Category Toxic Gases & Vapors
Synonyms 1-Buten-3-one; 1-Butenone; 3-Buten-2-one; 3-Oxobutene; Acetyl ethylene; delta (sup 3)-2-Butenone; Methylene acetone; Methyl vinyl ketone; Methyl vinyl ketone, stabilized with ca. 0.5% CH3CN, 0.5% CH3COOH, 0.5% H.Q.; MVK; Vinyl methyl ketone; gamma-Oxo-alpha-butylene; [ChemFinder]
Category Other Toxic Gases & Vapors
Description Colorless liquid with a pungent odor; [HSDB]
Sources/Uses Used as an intermediate in chemical synthesis, an alkylating agent, and a monomer in resins; it is present in cigarette smoke; [HSDB]
Comments Highly toxic; [Quick CPC] A lachrymator; Can cause liver injury (animal studies); Potential for pulmonary edema after heavy inhalation exposure;[HSDB] Liquid causes second or third degree burns on short contact; [CHRIS]
Reference Link HSDB
Exposure Assessment
Skin Designation (ACGIH) Yes
TIH Yes
Ceiling (ACGIH) 0.2 ppm
Vapor Pressure 83.9 mm Hg
Odor Threshold Low 0.2 ppm
Flammability (NFPA) 3: may ignite at ambient temperature
Adverse Effects
Toxic Pneumonitis Yes
Lacrimator Yes
Hepatotoxin Hepatotoxin, Secondary
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: METHYL VINYL KETONE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Activities Activities with risk of exposure:





Specialized Information Services   U.S. National Library of Medicine,
8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health
Privacy/Disclaimer Notice
Customer Service: tehip@teh.nlm.nih.gov
Last updated: January, 2009