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National Cancer Institute - U.S. National Institutes of Health - www.cancer.gov

Clinical Programs

Imaging and Molecular Therapeutics Section

Radiation Oncology Branch

Mission

The mission of the Imaging and Molecular Therapeutics Section of the Radiation Oncology Branch includes the following components:

  1. Plan and conduct pre-clinical and clinical research on the biologic and therapeutic effects of radiation administrated alone or in combination with other modalities of treatment.
  2. Develop novel technology and imaging-based approaches for radiation oncology.
  3. Investigate the natural history of disease in order to understand and evaluate means of diagnostic assessment for the purpose of optimizing treatment selections.
  4. Provide radiation therapy as well as general oncology consultations for patients admitted to other clinical services, in a collaborative approach.

Overview

The Radiation Oncology Branch (ROB) is part of the NCI Center for Cancer Research (CCR) and Division of Cancer Treatment and Diagnosis (DCTD).The major focus of the ROB is to design and conduct pre-clinical and clinical research on the biologic and therapeutic effects of radiation therapy. The ROB clinical team consists of clinical investigators who are board certified in radiation oncology, physicists, dosimetrists, residents, research nurses, and clinical staff nurses. The ROB clinical team also consists of clinical assistants, data managers and a social worker. As a team, the ROB is dedicated to conducting clinical trials based on sound translational research, while providing the highest possible clinical care for patients with various types of malignancies.

The trials that the ROB develops and conducts involve novel technology and/or imaging based approaches for radiation oncology. The ROB clinical staff work in close collaboration with other clinical and laboratory investigators within ROB, CCR, DCTD, as well as other Institutes including NHLBI, NIDDK, and NIA. In addition, the ROB provides consultations in a collaborative approach for patients admitted to other clinical services. CT simulation and MR image fusion a routine part of treatment planning. In addition, the ROB has the capability for radiosurgery, intensity-modulated 3-D conformal radiotherapy, real-time dose measurement, brachytherapy, and MR-guided procedures.

Research Team

Kevin A. Camphausen, M.D.
Branch Chief and Head, Imaging and Molecular
Therapeutics Section, Radiation Oncology Branch, CCR, NCI

Dr. Kevin A. Camphausen received his M.D. from Georgetown University in 1996. He completed his internship at Georgetown in 1997 and a residency in radiation oncology at the Joint Center for Radiation Therapy at Harvard Medical School in 2001. Dr. Camphausen spent 2 years working in the laboratory of Dr. Judah Folkman studying the interaction of angiogenesis inhibitors and radiotherapy. He joined the National Cancer Institute in July 2001 as a tenure-track investigator. He served as the Deputy Branch Chief beginning in April 2004 and was recently appointed Branch Chief of the Radiation Oncology Branch.

Deborah E. Citrin, M.D.
Principal Investigator
Imaging and Molecular Therapeutics Section, Radiation Oncology Branch, CCR, NCI

Dr. Deborah E. Citrin is a clinician and translational researcher in the Radiation Oncology Branch. She is a graduate of North Carolina State University and Duke University School of Medicine. Dr. Citrin completed her residency training at the National Cancer Institute and National Capital Consortium (Walter Reed Army Medical Center and National Naval Medical Center).

Dr. Citrin's laboratory research interests include normal tissue radiobiology, malignancies of the gastrointestinal tract, and novel molecular therapeutics combined with radiation.

Clinically, Dr. Citrin is involved in the care of patients with head and neck cancers, pediatric malignancies, gastrointestinal malignancies, thoracic malignancies, and melanoma.

Aradhana Kaushal, M.D.
Staff Clinician
Imaging and Molecular Therapeutics Section, Radiation Oncology Branch, CCR, NCI

Dr. Aradhana Kaushal graduated with a B.A./M.D., magna cum laude, from Boston University in 2002. She completed a year at the National Cancer Institute conducting research under the direction of Dr. Norman Coleman and Dr. David Gius, studying a possible mechanism for resistance of tumor cells to oxidative stress, which involves control of gene expression through transcription factor activation, methylation, and protein chaperone compartmentalization. She completed her internship in internal medicine in 2003 at Lenox Hill Hospital, a teaching hospital of New York University in Manhattan. Dr. Kaushal completed a residency in radiation oncology in 2007 at the Thomas Jefferson University Hospital in Philadelphia, Pa., and served as chief resident from 2006–2007. Her clinical focus is prostate and pediatric malignancies. Dr. Kaushal is board certified by the American Board of Radiology.

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