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| Topic: |
Digestive Diseases (DD) |
| Title: |
Colorectal Cancer Screening: Scientific Review. |
| Author: |
Walsh, J.M.E.; Terdiman, J.P. |
| Source: |
Journal of American Medical Association. 289(10): 1288-1296. March 2003. |
| Abstract: |
Screening for colorectal cancer clearly reduces colorectal cancer mortality, yet many eligible adults remain unscreened. Several screening tests are available, and various professional organizations have differing recommendations on which screening test to use. This article reports on a review that critically assessed the evidence for use of the available colorectal cancer screening tests, including fecal occult blood tests, sigmoidoscopy, colonoscopy, double-contrast barium enema, and newer tests, such as virtual colonoscopy and stool-based molecular screening. Results showed that randomized controlled trials have shown that fecal occult blood testing can reduce colorectal cancer incidence and mortality. Case-control studies have shown that sigmoidoscopy is associated with a reduction in mortality, and observational studies suggest colonoscopy is effective as well. Combining fecal occult blood testing and sigmoidoscopy may decrease mortality and can increase diagnostic yield. The authors conclude that at present, the available evidence does not currently support choosing one test over another. 1 figure. 3 tables. 105 references. |
| Format: |
Journal Article |
| Language: |
English. |
| Major Keywords: |
Digestive System Diseases. Colon Cancer. Screening. Diagnostic Tests. Patient Selection. |
| Minor Keywords: |
Research. Diagnosis. Colonoscopy. Health Promotion. Occult Blood. Sigmoidoscopy. Patient Care Management. Enema. |
| Publication Number: |
DDJA10149 |
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