Fluorophotometry Evaluation of Lubricant Eye Drops

This study has been completed.

Sponsored by:	Alcon Research
Information provided by:	Alcon Research
ClinicalTrials.gov Identifier:	NCT00347854

Purpose

The objective of this study is to evaluate the safety and efficacy of exaggerated use of Lubricant Eye Drops in a population of normal subjects by measuring corneal epithelial permeability to fluorescein.

Condition	Intervention
Healthy	Drug: Systane Free lubricant eye drops

Drug Information available for: Tetrahydrozoline Tetrahydrozoline hydrochloride

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Educational/Counseling/Training, Randomized, Double-Blind, Active Control, Parallel Assignment, Safety/Efficacy Study
Official Title:	Fluorophotometry Evaluation of Lubricant Eye Drops FID 105783

Further study details as provided by Alcon Research:

Primary Outcome Measures:

Epithelial permeability to fluorescein

Secondary Outcome Measures:

tear turnover rate

Estimated Enrollment:	40
Study Start Date:	April 2006

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Ages 18 and over

Exclusion Criteria:

No sodium fluorescein corneal staining at Screening Visit

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00347854

Locations

United States, Texas
Alcon
Fort Worth, Texas, United States, 76134

Sponsors and Collaborators

Alcon Research

Investigators

Study Director:

Mike Christensen

Alcon Research

More Information

Study ID Numbers:	C-05-06
Study First Received:	June 30, 2006
Last Updated:	July 3, 2006
ClinicalTrials.gov Identifier:	NCT00347854
Health Authority:	United States: Institutional Review Board

Keywords provided by Alcon Research:

Normal, healthy eyes (other than correction for visual acuity)

Study placed in the following topic categories:

Pseudoephedrine
Naphazoline
Oxymetazoline
Guaifenesin
Phenylephrine

Ephedrine
Phenylpropanolamine
Tetrahydrozoline
Healthy

Additional relevant MeSH terms:

Respiratory System Agents
Autonomic Agents
Sympathomimetics
Therapeutic Uses
Physiological Effects of Drugs

Vasoconstrictor Agents
Cardiovascular Agents
Peripheral Nervous System Agents
Pharmacologic Actions
Nasal Decongestants

ClinicalTrials.gov processed this record on January 14, 2009