Optical Coherence Tomography of Retinal Abnormalities Associated With Choroidal Nevus, Choroidal Melanoma and Choroidal Melanoma Treated With Iodine-125 Brachytherapy

This study is currently recruiting participants.

Verified by University of California, Los Angeles, September 2008

Sponsored by:	University of California, Los Angeles
Information provided by:	University of California, Los Angeles
ClinicalTrials.gov Identifier:	NCT00346372

Purpose

During regularly scheduled appointments, Optical Coherence Tomography (OCT) is performed on consented subjects. The OCT is a new type of camera that takes very detailed pictures inside of the eye and deeper into eye tissues. Optical Coherence Tomography imaging of intraocular tumors may lead to improved diagnosis and monitoring of tumors within the eye.

Condition
Ocular Melanoma

MedlinePlus related topics: Cancer Melanoma Moles

Drug Information available for: Iodine Cadexomer iodine

U.S. FDA Resources

Study Type:	Observational
Study Design:	Prospective

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both

Criteria

Inclusion Criteria:

1. Adults (18 years or older) with:

choroidal nevus greater than or equal to 3.0 mm in longest basal diameter, or greater than or equal to 1.25 mm in apical height or:
choroidal melanoma located in the posterior pole (4mm or less from the center of fovea or the border of the optic nerve head)

Exclusion Criteria:

1. Ocular media opacity in the tumor eye that prevents adequate functional testing or imaging and prior or concurrent retinal or choroidal disease in the tumor eye that prevents adequate functional testing or imaging

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00346372

Contacts

Contact: Tara A McCAnnel, MD, PhD	(310) 206-7484	young@jsei.ucla.edu
Contact: tarshia nulliah	3107949962	nulliah@jsei.ucla.edu

Locations

United States, California
Jules Stein Eye Institute	Recruiting
Los Angeles, California, United States, 90095
Contact: tarshia nulliah 310-794-9962 nulliah@jsei.ucla.edu

Sponsors and Collaborators

University of California, Los Angeles

Investigators

Principal Investigator:

Bradley R Straatsma, MD, JD

Jules Stein Eye Institute, UCLA

More Information

Study ID Numbers:	UCLA IRB#03-11-052
Study First Received:	June 27, 2006
Last Updated:	September 9, 2008
ClinicalTrials.gov Identifier:	NCT00346372
Health Authority:	United States: Institutional Review Board

Keywords provided by University of California, Los Angeles:

Ocular Melanoma
Optical Coherence Tomography
Eye Tumor
Choroidal Melanoma
Uveal Melanoma

Study placed in the following topic categories:

Ocular melanoma
Eye Neoplasms
Melanoma
Neuroendocrine Tumors
Melanoma of the choroid
Neuroectodermal Tumors
Uveal melanoma

Nevus, Pigmented
Neoplasms, Germ Cell and Embryonal
Intraocular melanoma
Iodine
Neuroepithelioma
Nevus
Congenital Abnormalities

Additional relevant MeSH terms:

Neoplasms
Neoplasms by Histologic Type
Neoplasms, Nerve Tissue
Nevi and Melanomas

ClinicalTrials.gov processed this record on January 14, 2009