Constrictive Pericarditis in the Adult Congenital Cardiac Population - Full Text View

Sponsored by:	Children's Healthcare of Atlanta
Information provided by:	Children's Healthcare of Atlanta
ClinicalTrials.gov Identifier:	NCT00268086

Purpose

The primary aim of this study is to determine the clinical and radiographic findings with constrictive pericarditis in the adult congenital population and determine the degree of right heart failure and dilation from pulmonary insufficiency in the presence of constrictive pericarditis

The secondary aim is to elucidate ways to better diagnose constrictive pericarditis and elucidate ways to diagnose right heart failure in the presence of constrictive pericarditis.

Condition
Congenital Disorders

U.S. FDA Resources

Study Type:	Observational
Study Design:	Natural History, Longitudinal, Defined Population, Retrospective Study
Official Title:	Constrictive Pericarditis in the Adult Congenital Cardiac Population

Further study details as provided by Children's Healthcare of Atlanta:

Estimated Enrollment:

15

Detailed Description:

Constrictive pericarditis is a notoriously difficult diagnosis to reach. There are no signs, symptoms or pathognomonic diagnostic tests for pericardial constriction. In the adult congenital patients, it is also difficult. In addition, with pulmonary insufficiency, constrictive pericarditis may mask the findings of progressive right sided ventricular dilation and heart failure.

The primary aim of this study is to determine the clinical and radiographic findings with constrictive pericarditis in the adult congenital population and determine the degree of right heart failure and dilation from pulmonary insufficiency in the presence of constrictive pericarditis

The secondary aim is to elucidate ways to better diagnose constrictive pericarditis and elucidate ways to diagnose right heart failure in the presence of constrictive pericarditis.

Study Design and Methodology:

Retrospective chart review - approximately 15 patients

Preoperative data:

ECHO and cath findings

Operative data:

Operative findings

Postoperative data:

ECHO and cath findings

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

patients in the adult congenital heart disease clinic who have been diagnosed or operated on with constrictive pericarditis

Exclusion Criteria:

those who do not meet the inclusion criteria

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00268086

Locations

United States, Georgia
Children's Healthcare of Atlanta
Atlanta, Georgia, United States, 30322

Sponsors and Collaborators

Children's Healthcare of Atlanta

Investigators

Principal Investigator:

Brian E Kogon, MD

Emory Univ. SOM Cardiothoracic Surgery at Children's Healthcare of Atlanta

More Information

Study ID Numbers:	05-123
Study First Received:	December 20, 2005
Last Updated:	June 12, 2007
ClinicalTrials.gov Identifier:	NCT00268086
Health Authority:	United States: Food and Drug Administration

Keywords provided by Children's Healthcare of Atlanta:

constrictive pericarditis
adult congenital patients
pulmonary insufficiency

Study placed in the following topic categories:

Heart Diseases
Pericarditis, Constrictive
Pericarditis

Additional relevant MeSH terms:

Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 15, 2009