tumor and normal tissues, ascites, and/or serum, and/or urine from women with malignant or premalignant gynecological conditions for which they are undergoing medically-indicated surgery, and normal tissues from women without malignancy who volunteer to donate serum and/or tissue at the time of medically indicated surgery.

Inclusion Criteria:

• All patients undergoing hysterectomy, or who have endometrial cancer, and are under routine surveillance.
• Patients may have received prior hormonal, cytotoxic chemotherapy, irradiation or surgical therapy.
• Healthy post-menopausal and peri-menopausal women.
• A consent form must be signed by the patient prior to study entry.

Exclusion Criteria:

Study Patients:

• Patients who do not have primary uterine corpus tumors.
• Patients with less than one gram of tumor tissue available to procurement.

Controls:

• Patients unwilling to have their medical records reviewed for height, weight, and general medical history (see attached data sheets).