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Research Funded by the Cancer Diagnosis Program

CDP New Grants for Fiscal Year 1999

Program Project (P01) Grant

Lawrence H. Einhorn, M.D.
The Biology of High Risk Germ Cell Neoplasia
Indiana University, IN

Regular (R01) Research Grants

Christopher C. Benz, M.D.
Defective Estrogen Receptors in Human Breast Tumors
University of California, San Francisco, CA

C. Richard Boland, M.D.
The Biology and Diagnosis of HNPCC
University of California, San Diego, CA

Sandra H. Bigner, M.D.
Growth Control and Cytogenetics of Malignant Gliomas
Duke University Medical Center, NC

Raju S. Chaganti, Ph.D.
Molecular Cytogenetics of Multiple Myeloma
Sloan-Kettering Institute For Cancer Research, NY

Mary J. Heeb, Ph.D.
Forms of Prostate-Specific Antigen and hK2 in Cancer
Scripps Research Institute, CA

Robert E. Hurst, Ph.D.
Bladder Cancer Biomarkers as Guides to Surgery and Therapy
University of Oklahoma, OK

James W. Jacobberger, Ph.D.
Standardized Multiparametric Cell Cycle Analysis
CWRU Cancer Research Center, OH

Gerrit Los, Ph.D
High Throughput Monitoring of Message Expression Signatures
University of California, San Diego, CA

David N. Louis, M.D.
Toward a Molecular Classification of Human Gliomas
Massachusetts General Hospital, MA

Donald C. Malins, Ph.D, D.Sc.
FT-IR/GC-MS Models for Predicting Prostate Cancer
Pacific Northwest Research Foundation, WA

Ralph P. Mason, Ph.D.
MR Measurement of Tumor pH, p02 and Vascularity In Vivo
U.T. Southwestern Medical Center at Dallas, TX

Michael F. Press, M.D., Ph.D.
Pathobiology of Breast Cancer and Hormone Receptors
Univ. of Southern CA / Norris Cancer Center, CA

Kenneth R. Shroyer, M.D., Ph.D.
Telomerase and HPV in Pap Smears and Cervical Biopsies
University of Colorado Health Sciences Center, CO

Jonathan W. Uhr, M.D.
Early Detection/Characterization of Tumor Cells in Blood
University of Texas Southwestern, TX

MERIT (R37) Award

Manuel Perucho, Ph.D.
Molecular Pathogenesis of Cancer of Mutator Phenotype
The Burnham Institute, CA

R29 (FIRST) Awards

Amy E. Noffsinger, M.D.
Microsatellite Instability and Colonic Neoplasia in IBD
University of Cincinnati, OH

Leo L. Cheng, Ph.D.
Evaluation of Astrocytomas with HRMAS 1HMR Spectroscopy
Massachusetts General Hospital, MA

Phase II STTR Grant (R42)

Robert C. Leif, Ph.D.
Detection of Macromolecules with Quantum Dyes
Newport Instruments, CA

Phase II SBIR Grants (R44)

Hank Chen, M.S.
Decision Support Software to Triage for Skin Cancer
West Portal Software Corporation, CA

Kenneth R. Castleman, Ph.D.
Wavelet-Based Automated Chromosome Identification
Perceptive Scientific Instruments, Inc., TX

Boris Gorbovitski, Ph.D.
Color DNA Sequencing Apparatus for Clinical Diagnosis
SUNY at Stony Brook, NY

Small Grant (R03)

H. Phillip Koeffler, M.D.
Discovery of New Secreted Proteins of Pancreatic Cancer
Cedars-Sinai Research Institute, CA

Academic Research Enhancement Award (R15)

Carl V. Hamby, Ph.D.
Detection of Metastasis Antigens in Melanoma
New York Medical College, NY

Awards in Response to RFA CA-97-011, Novel Technologies for Evaluation of Molecular Alterations in Tissue

Exploratory (R21) Grant

Konstantin Khrapko, Sc.D.
"Global Competitive PCR" for Studying Gene Expression
Massachusetts General Hospital, MA

Regular (R01) Research Grants

Daniel Pinkel, Ph.D.
Genome-wide Analysis of DNA Copy Number by Array CGH
University of California, San Francisco, CA

Peter Wilding, Ph.D.
Parallel and High Throughput Microsample Processing
University of Pennsylvania, PA

Cooperative Agreement (U01 and U19) Grants Awarded in Response to RFA CA98-027, Director's Challenge: Toward a Molecular Classification of Tumors

Patrick O. Brown, M.D., Ph.D.
A Cancer Taxonomy Based on Gene Expression Patterns
Stanford University, CA

Wing C. Chan, M.D.
Molecular Classification of B-cell Lymphoma
University of Nebraska Medical Center, NE

William L. Gerald, M.D., Ph.D.
Molecular Classification of Prostate Cancer
Sloan-Kettering Institute for Cancer Research, NY

John C. Gutheil, M.D.
Molecular Characterization of Early Stage Prostate Cancer
Sidney Kimmel Cancer Center, CA

Samir M. Hanash, M.D., Ph.D.
Toward a Molecular Classification of Tumors
The University of Michigan, MI

Steven W. Johnson, Ph.D.
Molecular Classification of Ovarian Tumors
University of Pennsylvania, PA

David M. Livingston, M.D.
Gene Expression Analysis of Cancers of the Prostate and Lung
Dana-Farber Cancer Institute, MA

Jerry Radich, M.D.
Gene Expression Profile of Progression and Response in CML
Fred Hutchinson Cancer Research Center, WA

Louise C. Showe, Ph.D.
CTCL Staging Using Gene Expression Profiles
The Wistar Institute, PA

James C. Willey, M.D.
Gene Expression Indices in Chemoresistant Lung Cancer
Medical College of Ohio, OH

Grants Awarded in Response to RFA CA99-005, Technologies for Generation of Full-Length Mammalian cDNA

Exploratory (R21) Grants

Michael F. Clarke, M.D.
Technologies for Generation of Full-Length Mammalian cDNA
The University of Michigan, MI

Sergey M. Kalachikov, Ph.D.
Generation of Representative Full-Length cDNA Libraries
Columbia University, NY

Ewen F. Kirkness, Ph.D.
A Novel Strategy for Cloning Full-length cDNAs
The Institute for Genomic Research, MD

William A. Riedl, M.S.
Full-Length mRNA and cDNA Methodology
Expressed Genomics, LLC, WI

Zhidong Xu, Ph.D.
Comprehensive Methods for Full-Length cDNA Cloning
University of California, San Francisco, CA

Regular (R01) Research Grants

Jerry Pelletier, Ph.D.
Improved Technologies for Full-Length cDNA Generation
McGill University, Montreal, Canada

Vinayaka R. Prasad, Ph.D.
Novel RTs for construction of full-length cDNA libraries
Albert Einstein College of Medicine, NY

M. Bento Soares, Ph.D.
A Two-pronged Strategy to Generate Full-Length cDNAs
The University of Iowa, IA

R21 Award in Response to PA-98-008, Exploratory/Developmental Grants in Diagnostic Cancer Imaging

Christoph Plass, Ph.D.
Methylation in AML
The Ohio State University, OH

R21 Awards in Response to PA-98-022, Exploratory Studies in Cancer Diagnostics

Dario C. Altieri, M.D.
Diagnosis of Large Cell Lymphoma by Survivin Expression
Yale University, CT

Andre T. Baron, Ph.D.
Circulating sErbB1 Levels as Diagnostic Tumor Biomarkers
Mayo Foundation Rochester, MN

Gerry R. Boss, M.D.
Measurement of Ras Activation in Lung Cancer
University of California, San Diego, CA

David E. Burstein, M.D.
Immuno-detection of Oncogenic Pathway Phosphorylations
Mount Sinai School of Medicine, NY

Ratna Chakrabarti, Ph.D.
Molecular Markers for Prostate Cancer
University of Central Florida, FL

Anthony D. Elias, M.D.
Minimal Residual Tumor in Small Cell Lung Cancer
Dana-Farber Cancer Center, MA

Edward W. Gabrielson, M.D.
Microsatellite Markers of DCIS Prognosis
Johns Hopkins University School of Medicine, MD

Goar Gevorkian, Ph.D.
Phage Display-Generated Immunoreagents for HPV Infection
Universidad Nacional Autonoma de Mexico, Mexico

L. Michael Glode, M.D.
Molecular Markers for Prostate Cancer Detection
University of Colorado Health Sciences Center, CO

W. Edward Highsmith, Ph.D.
High Density cDNA Array-Based Classification of Tumors
University of Maryland, Baltimore, MD

H. Phillip Koeffler, M.D.
Identification of Novel Secreted Molecules of Cancer
Cedars-Sinai Research Institute, CA

Vassillios Papadopoulos, Ph.D.
Peripheral Benzodiazepine Receptor in Breast Cancer
Georgetown University, DC

Sandra A. Rempel, Ph.D.
SPARC: A diagnostic Marker for Invasive Meningioma
Henry Ford Health System, MI

David L. Rimm, M.D., Ph.D.
A Molecular Clonality Assay for Early Cancer Diagnosis
Yale University, CT

David L. Rimm, M.D., Ph.D.
QB Cytology, a Novel Method for Detection of Circulating Cancer Cells
Yale University, CT

Scott A. Waldman, M.D., Ph.D.
Guanylyl Cyclase C in Blood and Colorectal Cancer
Jefferson Medical College, PA

R21 Award in Response to PA-98-042, Exploratory Grants for Correlative Laboratory Studies and Clinical Trials

David L. Rimm, M.D., Ph.D.
The Value of Met for Prediction of Metastasis in Breast Cancer
Yale University, CT

R01 and R21 Awards in Response to PA-98-099, Correlative Studies Using Specimens from Multi-Institutional Treatment Trials

Carol R. Bradford, M.D.
Markers of Treatment Response in Advanced Laryngeal Cancer
University of Michigan, MI

Ursula R. Kees, Ph.D.
Molecular Genetic Lesions, assessed by Quantitative PCR, and Clinical Outcome in Pediatric ALL Patients
TVW Telethon Institute for Child, West Perth, Australia

John Shaughnessy, Ph.D.
Correlative Studies Using Specimens from SWOG 9321
University of Arkansas for Medical Sciences, AR

R21 Awards in Response to PAR-98-047, Innovative Approaches to Developing New Technologies

David G. Cory, Ph.D.
High Resolution NMR Imaging and Scattering
Massachusetts Institute of Technology, MA

Cheng S. Lee, Ph.D.
2-D Protein Analysis Using Microchip-Mass Spectrometry
University of Maryland, College Park, MD

Awards in Response to PAR-98-066, Innovative Technologies for the Molecular Analysis of Cancer: SBIR/STTR Initiative

John C. Gerdes, Ph.D.
Quantitation and Archiving of Gene Expression
Molecular Innovations Inc., CO

Marianna M. Goldrick, Ph.D.
Detection and Quantitation of Fusion mRNAs in Leukemia
Ambion, Inc., TX

Frederick S. Hagen, Ph.D.
Affinity and Transcriptase Technologies
Icogen Corporation, WA

Eric S. Lader, Ph.D.
Development of RNA Friendly, Histological Fixatives
Ambion, Inc., TX

Nadia Lifshitz, Ph.D.
Development of High-throughput DNA Sequencing Instrument for High-resolution Identification of Mutations in Mixed Populations of DNA Molecules
BioPhotonics Corporation, NY

Joseph A. Monforte, Ph.D.
High-Throughput Expression Monitoring of Multiplexed Cancer Gene Sets
GeneTrace Systems, Inc., CA

Peter Richterich, Ph.D.
Software for Sequencing-based mutation detection
CodonCode Corporation, MA

Awards in Response to PAR-98-067, Innovative Technologies for the Molecular Analysis of Cancer: Phased Innovation Award

Robert W. Basedow, Ph.D.
Hyperspectral System for Molecular Analysis of Cancer
Raytheon Optical Systems, CT

Paul M. Lizardi, Ph.D.
Messenger RNA Profiling by Single Molecule Counting
Yale University, CT

John M. Ramsey, Ph.D.
Microfabricated Microfluidic Devices for Comprehensive High-Throughput Cellular Protein Analysis
Oak Ridge National Library, TN

Stanley E. Shackney, M.D.
Molecular Profiling of Cells by Laser Scanning Cytometry
Allegheny University of the Health Sciences, PA

Robert H. Singer, Ph.D.
FISH & CHIPS: Single Cell Expression of Cancer Genes
Albert Einstein College of Medicine, NY

Awards in Response to PAR-98-092, Shared Resources for Scientists Outside NCI Cancer Centers

Adi F. Gazdar, M.D.
A Unique Tissue and Tumor Processing Facility
UT Southwestern Medical Center, TX

Laura W. Lamps, M.D.
Experimental Pathology Shared Resource Laboratory
University of Arkansas for Medical Sciences, AR

David L. Nelson, Ph.D.
Baylor College of Medicine Microarray Facility for NCI Funded Projects
Baylor College of Medicine, TX

William C. Raschke, Ph.D.
Molecular Analysis Resource for Primary Human Cancers
Sidney Kimmel Cancer Center, CA

P01 Award in Response to PAR-97-021, High-Throughput Technologies to Detect Alterations in Tumors

David Sidransky, M.D.
High Throughput Genetic Analysis of Bladder Cancer
Johns Hopkins University School of Medicine, MD

Section Last Updated: 07/24/07