Our Science – Pastrana Website

Diana V. Pastrana, Ph.D.

Laboratory of Molecular Biology Biotherapy Section Staff Scientist National Cancer Institute Building 37, Room 5124 37 Convent Drive Bethesda, MD 20892 Phone:   301-594-7059 Fax:   301-402-1344 E-Mail:   pastrand@mail.nih.gov

Biography

B.S. Hartwick College, Oneonta, New York.

Ph.D. Johns Hopkins University, School of Hygiene and Public Health. Baltimore, Maryland. Research focused on a filarial (Brugia malayi) homologue of Macrophage Inhibitory Factor (MIF)

Postdoctoral Work: NCI, NIH, Laboratory of Cellular Oncology, Neoplastic Disease section. Interests included neutralization assays for Papillomavirus.

Currently Staff Scientist: NCI, NIH, Laboratory of Molecular Biology, Biotherapy section.

Research

- Interaction of Pseudomonas Exotoxin A (and immunotoxins) with mammalian cells including receptor binding, retrograde transport, and mechanisms of killing.
- Enhancement of tumor cell apoptosis using immunotoxins plus other agents.

This page was last updated on 7/15/2008.