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Sponsored by: |
National Institute on Drug Abuse (NIDA) |
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Information provided by: | National Institute on Drug Abuse (NIDA) |
ClinicalTrials.gov Identifier: | NCT00618943 |
This research aims to identify efficacious strategies for treating tobacco dependence among adolescent smokers with co-occurring psychiatric disorders. Adolescent smoking remains a significant public health issue with 23% of high school students reporting smoking a cigarette in the past month1. Smoking rates are two to four times higher among adolescents with psychiatric disorders such as attention deficit disorders, conduct disorder, depression, anxiety disorders, and alcohol and illicit drug dependencies2-4.
Empirical investigations of adolescent tobacco treatment interventions number less than 50 with many of the studies criticized for methodological problems (i.e., follow up < 6 months, poor retention, lack of control or comparison groups)2,5, 6. There have been no unequivocal successes; however, promising interventions include stage-based, cognitive behavioral (CBT), and multicomponent treatments2, 7. Additionally, the nicotine patch is well tolerated and safe among adolescents8 and rarely abused9. Less than a third of adolescent tobacco users report intention to quit in the near future2, 10, 11; thus, it seems critical that cessation interventions for this complex group be designed to assist smokers at all stages of readiness through the quitting process. A stepped care approach has the potential of matching more intensive services to those ready for and in need of greater treatment. Interventions delivered in health care settings have the appeal of broad reach.
The primary specific aims of this research are to evaluate, in a randomized clinical trial (N=160), the efficacy of a stepped care intervention for treating smoking among adolescents recruited from outpatient psychiatry settings. To our knowledge, this would be the first study to examine outpatient psychiatry settings for treating tobacco dependence in adolescents. The stepped care intervention combines expert-system contacts, individual CBT sessions, and 12-weeks of nicotine replacement therapy (NRT).
Condition | Intervention | Phase |
---|---|---|
Tobacco Use Cessation Tobacco Use Disorder |
Behavioral: Tobacco Use Cessation |
Phase III |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Open Label, Active Control, Single Group Assignment, Efficacy Study |
Official Title: | Treating Tobacco Dependence in Adolescents With Co-Occurring Psychiatric Disorders |
Estimated Enrollment: | 160 |
Study Start Date: | April 2008 |
Estimated Study Completion Date: | April 2010 |
Estimated Primary Completion Date: | April 2010 (Final data collection date for primary outcome measure) |
Ages Eligible for Study: | 13 Years to 25 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contact: Judith J Prochaska, PhD, MPH | (415) 476-7695 | JProchaska@lppi.ucsf.edu |
United States, California | |
UCSF Langley Porter Psychiatric Institute | Recruiting |
San Francisco, California, United States, 94114 | |
Contact: Anayansi Lombardero 415-476-8336 | |
San Mateo County Mental Health | Recruiting |
San Mateo, California, United States, 94403 | |
Contact: Anayansi Lombardero 415-476-8336 | |
Edgewood Center for Children and Families | Recruiting |
San Bruno, California, United States, 94066 | |
Contact: Anayansi Lombardero 415-476-8336 |
Principal Investigator: | Judith J Prochaska, PhD, MPH | University of California, San Francisco |
Responsible Party: | University of California, San Francisco, Department of Psychiatry ( Judith J. Prochaska, PhD, MPH ) |
Study ID Numbers: | NIDA-09253, P50-DA09253 |
Study First Received: | February 15, 2008 |
Last Updated: | October 30, 2008 |
ClinicalTrials.gov Identifier: | NCT00618943 |
Health Authority: | United States: Federal Government |
Nicotine polacrilex Nicotine Mental Disorders |
Tobacco Use Disorder Substance-Related Disorders Disorders of Environmental Origin |
Pathologic Processes Disease |