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Sponsored by: |
Hadassah Medical Organization |
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Information provided by: | Hadassah Medical Organization |
ClinicalTrials.gov Identifier: | NCT00722228 |
This study is based on the finding that tumor cells that are grown in the laboratory can be modified in such a way that, when injected to the patient, they will stimulate his/her immune response. This approach will be evaluated in patients with colorectal, gastric, ovarian, breast or lung epithelial cancer. Tumor cells grown in the laboratory will be modified to make them stimulatory to the immune system, irradiated to kill them, and injected to the patient eight times at two-week intervals . This protocol is expected to prolong survival of metastatic epithelial cancer patients.
Condition | Intervention | Phase |
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Colorectal Cancer Ovarian Cancer Gastric Cancer Breast Cancer Lung Cancer |
Biological: Allogeneic whole epithelial tumor cells, DNP-conjugated and irradiated |
Phase I Phase II |
Study Type: | Interventional |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contact: Arik , Tzukert, DMD | : 00 972 2 6776095 | arik@hadassah.org.il |
Contact: Hadas , Lemberg, PhD | 00 972 2 6777572 | : lhadas@hadassah.org.il |
Israel | |
Hadassah Medical Organization | |
Jerusalem, Israel, 91120 |
Study ID Numbers: | 0359-08-HMO-CTIL |
Study First Received: | July 23, 2008 |
Last Updated: | July 24, 2008 |
ClinicalTrials.gov Identifier: | NCT00722228 |
Health Authority: | Israel: Israeli Health Ministry Pharmaceutical Administration |
Thoracic Neoplasms Gonadal Disorders Gastrointestinal Diseases Colonic Diseases Urogenital Neoplasms Ovarian Diseases Rectal Diseases Genital Diseases, Female Stomach Diseases Respiratory Tract Diseases Lung Neoplasms Stomach Neoplasms Breast Diseases Endocrine Gland Neoplasms Ovarian cancer |
Digestive System Neoplasms Ovarian Neoplasms Skin Diseases Genital Neoplasms, Female Breast Neoplasms Endocrine System Diseases Stomach cancer Intestinal Diseases Intestinal Neoplasms Digestive System Diseases Lung Diseases Gastrointestinal Neoplasms Endocrinopathy Colorectal Neoplasms |
Respiratory Tract Neoplasms Neoplasms Neoplasms by Site Adnexal Diseases |