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Sponsored by: |
HaEmek Medical Center, Israel |
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Information provided by: | HaEmek Medical Center, Israel |
ClinicalTrials.gov Identifier: | NCT00512564 |
Iron overload is well study in Thalassemia patients and it's not only related to blood transfusions, since intestinal iron absorption is also increased in those patients. Sickle cell patients didn't developed significant clinical symptoms and signs of iron overload in spite frequent transfusions. The purpose of this study is to assess the iron overload in Sickle cell anemia and Sickle cell Thalassemia patients using clinical parameters and laboratory studies including Non Transferrin Binding Iron, Labile Iron and Hepcidin, in order to determine the cardiac and liver iron.
Condition |
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Sickle Cell Anemia Sickle Cell Thalassemia |
Study Type: | Observational |
Study Design: | Natural History, Cross-Sectional, Defined Population, Retrospective/Prospective Study |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Contact: Ariel Koren, MD | 972-4-6495576 ext 5576 | koren_a@clalit.org.il |
Contact: Carina Levin, MD | 972-4-6494189 ext 4189 | levin_c@clalit.org.il |
Israel | |
Pediatric Hematology Unit - HaEmek Medical Center | |
Afula, Israel, 18101 | |
Pediatric Hematology Unit - HaEmek Medical Center | |
Afula, Israel, 1810 |
Principal Investigator: | Ariel Koren, MD | Pediatric Hematology Unit, Ha'Emek Medical Center |
Study ID Numbers: | 0087-07-EMC |
Study First Received: | August 5, 2007 |
Last Updated: | August 6, 2007 |
ClinicalTrials.gov Identifier: | NCT00512564 |
Health Authority: | Israel: Ministry of Health |
Sickle Cell Anemia Sickle Cell Thalassemia Iron overload Non transferrin binding iron Hepcidin |
Metabolic Diseases Hematologic Diseases Anemia Anemia, Hemolytic Iron Metabolism Disorders Thalassemia Sickle cell anemia Anemia, Hemolytic, Congenital |
Genetic Diseases, Inborn Hemoglobinopathies Iron Overload Metabolic disorder Hemoglobinopathy Iron Anemia, Sickle Cell |