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| Sponsored by: |
Massachusetts General Hospital |
|---|---|
| Information provided by: | Massachusetts General Hospital |
| ClinicalTrials.gov Identifier: | NCT00742235 |
Purpose
Vitamin D deficiency (low levels of vitamin D in the blood) is a common problem. A recently discovered protein, called hCAP18, likely plays an important role in the immune system and may depend on adequate levels of vitamin D. It is not known what levels of vitamin D are needed to allow the body to make this protein. Nor is it known if giving vitamin D to people who are found to be deficient will help boost levels of hCAP18. This study aims to clarify the relationship between vitamin D levels and hCAP18.
| Condition | Intervention |
|---|---|
|
Healthy Subjects Vitamin D Deficiency |
Drug: ergocalciferol |
| Study Type: | Interventional |
| Study Design: | Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment |
| Official Title: | hCAP18 Levels and Vitamin D Deficiency in Healthy Subjects |
| Estimated Enrollment: | 100 |
| Study Start Date: | July 2007 |
| Estimated Study Completion Date: | January 2009 |
| Estimated Primary Completion Date: | December 2008 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
1: Experimental
Vitamin D deficient subjects treated with ergocalciferol.
|
Drug: ergocalciferol
Ergocalciferol 50,000 IU given every other day for 5 total doses
|
Eligibility| Ages Eligible for Study: | 18 Years to 80 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Ishir Bhan, M.D., M.P.H. | 617-726-3934 | ibhan@partners.org |
| United States, Massachusetts | |
| Massachusetts General Hospital | Recruiting |
| Boston, Massachusetts, United States, 02114 | |
| Contact: Dorothy Sullivan, RN 617-726-5382 DSULLIVAN18@PARTNERS.ORG | |
| Principal Investigator: Ishir Bhan, M.D., M.P.H. | |
| Principal Investigator: | Ishir Bhan, MD MPH | Massachusetts General Hospital |
More Information
| Responsible Party: | Massachusetts General Hospital ( Ishir Bhan ) |
| Study ID Numbers: | 2008-P-0003000/1 |
| Study First Received: | August 25, 2008 |
| Last Updated: | August 25, 2008 |
| ClinicalTrials.gov Identifier: | NCT00742235 |
| Health Authority: | United States: Institutional Review Board |
|
Vitamin D Deficiency Vitamin D Malnutrition Avitaminosis |
Ergocalciferols Nutrition Disorders Healthy Deficiency Diseases |
|
Growth Substances Vitamins Physiological Effects of Drugs |
Bone Density Conservation Agents Micronutrients Pharmacologic Actions |
