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Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news on the impact of the environment on human health. EHP is published by the National Institute of Environmental Health Sciences and its content is free online. Print issues are available by paid subscription.DISCLAIMER
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Comparative Toxicogenomics Database (CTD)

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Environmental Health Perspectives Volume 112, Number 4, March 2004
Environmental Health Perspectives Toxicogenomics March 2004 Selective silencing of genes through RNA interference (RNAi) is receiving a good deal of attention as a potential breakthrough therapy for gene-related diseases. Can the reality live up to the buzz? The Focus (p. A224) takes a look at the state of the knowledge of RNAi.
image credit: Photodisc; Joseph Tart/EHP

Purchase This Issue

  • Gene Silencing: A New Golden Age?
    A 224
  • Network Regulation by Ahr
    A 230 & 403
  • Mini-Monograph
    Genomics Expands Mechanism-Based Risk Assessments
    A 231 & 417

Perspectives


Editorial
p. A 210
  • Decoding the Riddle: The Dawn of RNAi for the Study of Gene-Gene and Gene-Environment Interactions
    Vilius Stribinskis and Kenneth S. Ramos
    [HTML] [ Download PDF]

Environews


Forum
p. A 216
  • Silent Advances
  • FDA Eyes Pharmacogenomics Data
  • Sequencing a Zoo
  • Cluster Busters
  • TXGnet: RNAi@elegansNet
    [HTML] [ Download PDF]
NCT Update
p. A 222 Focus
p. A 224 Science Selections
p. A 230

Toxicogenomics


Article

Unraveling Gene-Gene Interactions Regulated by Ligands of the Aryl Hydrocarbon Receptor
Johnson et al.
p. 403
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Workshop Summary

Applying New Biotechnologies to the Study of Occupational Cancer
Toraason et al.
p. 413
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Mini-Monograph: Genomics and Risk Assessment


Toxicogenomics in Risk Assessment: An Overview of an HESI Collaborative Research Program
Pennie et al.
p. 417
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The Utility of DNA Microarrays for Characterizing Genotoxicity
Newton et al.
p. 420
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Overview of an Interlaboratory Collaboration on Evaluating the Effects of Model Hepatotoxicants on Hepatic Gene Expression
Ulrich et al.
p. 423
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Clofibrate-Induced Gene Expression Changes in Rat Liver: A Cross-Laboratory Analysis Using Membrane cDNA Arrays
Baker et al.
p. 428
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Interlaboratory Evaluation of Rat Hepatic Gene Expression Changes Induced by Methapyrilene
Waring et al.
p. 439
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Cross-Site Comparison of Gene Expression Data Reveals High Similarity
Chu et al.
p. 449
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Quantitative PCR Deconstruction of Discrepancies between Results Reported by Different Hybridization Platforms
Goodsaid et al.
p. 456
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Overview of the Application of Transcription Profiling Using Selected Nephrotoxicants for Toxicology Assessment
Kramer et al.
p. 460
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Identification of Putative Gene-Based Markers of Renal Toxicity
Amin et al.
p. 465
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Dye-Bias Correction in Dual-Labeled cDNA Microarray Gene Expression Measurements
Rosenzweig et al.
p. 480
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Identification of Platform-Independent Gene Expression Markers of Cisplatin Nephrotoxicity
Thompson et al.
p. 488
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Database Development in Toxicogenomics: Issues and Efforts
Mattes et al.
p. 495
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Annotation and Cross-Indexing of Array Elements on Multiple Platforms
Mattes
p. 506
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