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Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news on the impact of the environment on human health. EHP is published by the National Institute of Environmental Health Sciences and its content is free online. Print issues are available by paid subscription.DISCLAIMER
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Environmental Health Perspectives Volume 93, 1991
Environmental Health Perspectives  1991 Target Genes in Chemical Carcinogenesis

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Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis
Yuspa-SH; Kilkenny A; Cheng-C; Roop-D; Hennings-H; Kruszewski-F; Lee-E; Strickland-J; Greenhalgh-DA
p. 3
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Three-dimensional structure of p21 in the active conformation and analysis of an oncogenic mutant
Wittinghofer-F; Krengel-U; John-J; Kabsch-W; Pai-EF
p. 11
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GTP-binding proteins as oncogenes in human tumors
McCormick-F
p. 17
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ras activation in human tumors and in animal model systems
Corominas-M; Sloan-SR; Leon-J; Kamino-H; Newcomb-EW; Pellicer A
p. 19
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Frequency and spectrum of c-Ki-ras mutations in human sporadic colon carcinoma, carcinomas arising in ulcerative colitis, and pancreatic adenocarcinoma
Burmer-GC; Rabinovitch-PS; Loeb-LA
p. 27
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The role of non-ras transforming genes in chemical carcinogenesis
Cooper-CS
p. 33
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Genetic changes during mouse skin tumorigenesis
Burns-PA; Bremner-R; Balmain A
p. 41
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Oncogenes and radiation carcinogenesis
Garte-SJ; Burns-FJ
p. 45
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Differential gene expression during multistage carcinogenesis
Bowden-GT; Krieg-P
p. 51
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Lessons learned from studies on tumor suppression by microcell-mediated chromosome transfer
Oshimura-M
p. 57
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Senescence as a mode of tumor suppression
Sager-R
p. 59
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Drosophila as a model system for molecular analysis of tumorigenesis
Mechler-BM; Strand-D; Kalmes A; Merz-R; Schmidt-M; Torok-I
p. 63
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Genetic analysis of the K-rev-1 transformation-suppressor gene
Kitayama-H; Matsuzaki-T; Sugimoto-Y; Ikawa-Y; Noda-M
p. 73
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Molecular and functional analysis of tumor-suppressor genes by transfection
Schafer-R; Iyer-J; Iten-E; Nirkko AC; Balmer-J; Klemenz-R
p. 79
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Functional in vitro assays for the isolation of cell transformation effector and suppressor genes
Zarbl-H; Kho-CJ; Boylan-MO; Van Amsterdam-J; Sullivan-RC; Hoemann-CD; Afshani-VL
p. 83
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Molecular determinants of metastatic transformation
Egan-SE; Wright-JA; Greenberg AH
p. 91
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Mechanisms of oncogene cooperation: activation and inactivation of a growth antagonist
Ragozzino-MM; Kuo A; DeGregori-J; Kohl-N; Ruley-HE
p. 97
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Identification of genes associated with tumor suppression in Syrian hamster embryo cells
Wiseman-RW; Montgomery-JC; Hosoi-J; Hou-EW; Cochran-CJ; Lamb-PW; Barrett-JC
p. 105
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Gene regulation and genetic susceptibility to neoplastic transformation: AP-1 and p80 expression in JB6 cells
Bernstein-LR; Ben-Ari-ET; Simek-SL; Colburn-NH
p. 111
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Chromosomal localization of putative tumor-suppressor genes in several human cancers
Yokota-J; Sugimura-T; Terada-M
p. 121
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Frequency and spectrum of mutations at codons 12 and 13 of the c-K-ras gene in human tumors
Capella-G; Cronauer-Mitra-S; Pienado-MA; Perucho-M
p. 125
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Oncogenes and tumor-suppressor genes
Lehman-TA; Reddel-R; Peiifer AM; Spillare-E; Kaighn-ME; Weston A; Gerwin-BI; Harris-CC
p. 133
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Activation of proto-oncogenes in human and mouse lung tumors
Reynolds-SH; Anderson-MW
p. 145
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Genetic studies on lung tumor susceptibility and histogenesis in mice
Malkinson AM
p. 149
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Genetic regulation of mammary carcinogenesis in the rat by susceptibility and suppressor genes
Gould-MN; Zhang-R
p. 161
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Loss of amplified genes by poly(ADP-ribose) polymerase inhibitors
Nagao-M; Nakayasu-M; Aonuma-S; Shima-H; Sugimura-T
p. 169
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Nonmutagenic mechanisms in carcinogenesis: role of protein kinase C in signal transduction and growth control
Weinstein-IB
p. 175
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Biochemical markers associated with the stages of promotion and progression during hepatocarcinogenesis in the rat
Pitot-HC; Dragan-Y; Sargent-L; Xu-YH
p. 181
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Aberrant expression and function of gap junctions during carcinogenesis
Yamasaki-H
p. 191
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Is there a critical target gene for the first step in carcinogenesis?
Kennedy AR
p. 199
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An overview of peroxisome proliferator-induced hepatocarcinogenesis
Rao-MS; Reddy-JK
p. 205
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Mechanisms of action of okadaic acid class tumor promoters on mouse skin
Fujiki-H; Suganuma-M; Yoshizawa-S; Nishiwaki-S; Winyar-B; Sugimura-T
p. 211
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Skeletal concentrations of lead, cadmium, zinc, and silver in ancient North American Pecos Indians
Ericson-JE; Smith-DR; Flegal AR
p. 217
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Ultrastructural immunohistochemical localization of Clara cell secretory protein in pulmonary epithelium of rabbits
Patton-SE; Gupta-RP; Nishio-S; Eddy-EM; Jetten AM; Plopper-CG; Nettesheim-P; Hook-GE
p. 225
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Target organs in chronic bioassays of 533 chemical carcinogens
Gold-LS; Slone-TH; Manley-NB; Bernstein-L
p. 233
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Chemicals associated with site-specific neoplasia in 1394 long-term carcinogenesis experiments in laboratory rodents [published erratum appears in 1991 Nov;95: 213]
Huff-J; Cirvello-J; Haseman-J; Bucher-J
p. 247
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Sequential measurements of bone lead content by L X-ray fluorescence in CaNa2EDTA-treated lead-toxic children
Rosen-JF; Markowitz-ME; Bijur-PE; Jenks-ST; Wielopolski-L; Kalef-Ezra-JA; Slatkin-DN
p. 271
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