Image |
Description |
File Size |
![“Mel-c melanocyte”](mcb/images/hhmi_thumb.jpg) |
Mel-c melanocyte treated with cytochalasin and stained for F-actin (blue), microtubules (red), and the melanosome marker TRP-1 (green). |
137 KB |
![“Aggregated Dictyostelium”](mcb/images/dicty_thumb.jpg) |
Aggregated Dictyostelium cells stained for F-actin (red) and myosin IC (green). Yellow indicates overlapping localization. |
14.4 KB |
![“Sequence #1 thumbnail image”](mcb/images/seq1_thumb.jpg) |
Sequence #1: Melanosome movements in a heavily melanized dilute melanocyte. |
574 KB |
![“Sequence #2 thumbnail image”](mcb/images/seq2_thumb.jpg) |
Sequence #2: Melanosome movements in a lightly melanized dilute melanocyte. |
470 KB |
![“Sequence #3 thumbnail image”](mcb/images/seq3_thumb.jpg) |
Sequence #3: Melanosome movements within the thin dendrite of a dilute melanocyte. |
235 KB |
![“Sequence #4 thumbnail image”](mcb/images/seq4_thumb.jpg) |
Sequence #4: Melanosome movements within a large dendritic extension of a dilute melanocyte. |
544 KB |
![“Sequence #5a thumbnail image”](mcb/images/seq5a_thumb.jpg) |
Sequence #5a: A dilute melanocyte before the addition of nocodazole (notice cell extension). |
882 KB |
![“Sequence #5b thumbnail image”](mcb/images/seq5b_thumb.jpg) |
Sequence #5b: After the addition of nocodazole (the same cell shown in seq#5a). |
194 KB |
![“Sequence #6a thumbnail image”](mcb/images/seq6a_thumb.jpg) |
Sequence #6a: A dilute melanocyte before the addition of nocodazole. (Notice cell center.) |
306 KB |
![“Sequence #6b thumbnail image”](mcb/images/seq6b_thumb.jpg) |
Sequence #6b: After the addition of nocodazole (the same cell shown in seq#6a). |
264 KB |
![“Sequence #7 thumbnail image”](mcb/images/seq7_thumb.jpg) |
Sequence #7: 30 minutes after nocodazole washout (the same cell shown in seq#6b) |
779 KB |
![“Sequence #8 thumbnail image”](mcb/images/seq8_thumb.jpg) |
Sequence #8: Melanosome dynamics within a well-spread wild type melanocyte exhibiting an even distribution of melanosomes. |
507 KB |
![“Sequence #9a thumbnail image”](mcb/images/seq9a_thumb.jpg) |
Sequence #9a: Low mag image of melanosome dynamics within a wild type melanocyte exhibiting a prominent accumulation of melanosomes at the dendritic tip. |
909 KB |
![“Sequence #9b thumbnail image”](mcb/images/seq9b_thumb.jpg) |
Sequence #9b: High mag image of melanosome dynamics within the dendrite of the cell shown in seq.#9a. |
509 KB |
![“Sequence #9c1 thumbnail image”](mcb/images/seq9c1_thumb.jpg) |
Sequence #9c1: Movements of individual melanosomes within the dendrite shown in seq.#9b (centripetal). |
46 KB |
![“Sequence #9c2 thumbnail image”](mcb/images/seq9c2_thumb.jpg) |
Sequence #9c2: Movements of individual melanosomes within the dendrite shown in seq.#9b (centripetal). |
61 KB |
![“Sequence #9c3 thumbnail image”](mcb/images/seq9c3_thumb.jpg) |
Sequence #9c3: Movements of individual melanosomes within the dendrite shown in seq.#9b (centrifugal). |
61 KB |
![“Sequence #10a thumbnail image”](mcb/images/seq10a_thumb.jpg) |
Sequence #10a: Low mag image of melanosome dynamics within a wild type melanocyte exhibiting a prominent accumulation of melanosomes along the edges of its dendritic extension. |
762 KB |
![“Sequence #10b thumbnail image”](mcb/images/seq10b_thumb.jpg) |
Sequence #10b: High mag image of melanosome dynamics within a wild type melanocyte exhibiting a prominent accumulation of melanosomes along the edges of its dendritic extension. |
1009 KB |
![“Sequence #10c1 thumbnail image”](mcb/images/seq10c1_thumb.jpg) |
Sequence #10c1: Movements of individual melanosomes within the dendrite shown in seq.#10b (centripetal) |
157 KB |
![“Sequence #10c2 thumbnail image”](mcb/images/seq10c2_thumb.jpg) |
Sequence #10c2: Movements of individual melanosomes within the dendrite shown in seq.#10b (centripetal) |
101 KB |
![“Sequence #10c3 thumbnail image”](mcb/images/seq10c3_thumb.jpg) |
Sequence #10c3: Movements of individual melanosomes within the dendrite shown in seq.#10b (centripetal) |
66 KB |
![“Sequence #10c4 thumbnail image”](mcb/images/seq10c4_thumb.jpg) |
Sequence #10c4: Movements of individual melanosomes within the dendrite shown in seq.#10b (centrifugal). |
51 KB |
![“Sequence #10c5 thumbnail image”](mcb/images/seq10c5_thumb.jpg) |
Sequence #10c5: Movements of individual melanosomes within the dendrite shown in seq.#10b (centrifugal). |
36 KB |
![“Sequence #11 thumbnail image”](mcb/images/seq11_thumb.jpg) |
Sequence #11: Generation of a dilute-like phenotype by expression of the myosin Va tail domain. |
1930 KB |
![“Sequence #12a thumbnail image”](mcb/images/seq12a_thumb.jpg) |
Sequence #12a: Melanosome dynamics in microtubule-depleted wild type melanocytes. |
307 KB |
![“Sequence #12b thumbnail image”](mcb/images/seq12b_thumb.jpg) |
Sequence #12b: Melanosome dynamics in mirotubule-depleted dilute melanocytes. |
302 KB |