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Motion Analysis of Sit-to-Stand Movements in Children With Spastic Diplegia
This study is not yet open for participant recruitment.
Verified by Far Eastern Memorial Hospital, April 2006
Sponsors and Collaborators: Far Eastern Memorial Hospital
National Taiwan University
Information provided by: Far Eastern Memorial Hospital
ClinicalTrials.gov Identifier: NCT00314301
  Purpose

The purpose of this study is to compare movement variations before and after the loaded training, with kinematics, kinetics, and electromyography, in children with spastic diplegia and to further discuss mechanisms of the loaded training.


Condition Intervention
Cerebral Palsy
Device: loaded sit-to-stand training

MedlinePlus related topics: Cerebral Palsy Paralysis
U.S. FDA Resources
Study Type: Interventional
Study Design: Educational/Counseling/Training, Randomized, Open Label, Uncontrolled, Crossover Assignment, Safety/Efficacy Study
Official Title: Motion Analysis of Sit-to-Stand Movements in Children With Spastic Diplegia Before and After Loaded Sit-to-Stand Training

Further study details as provided by Far Eastern Memorial Hospital:

Primary Outcome Measures:
  • kinematic measures of lower extremity and the whole body
  • kinetic measures of lower extremity and the whole body
  • electromyographic measures of lower extremity and the whole body

Estimated Enrollment: 20
Study Start Date: April 2006
Estimated Study Completion Date: September 2007
Detailed Description:

Subjects: This study will recruit twenty children who are aged between 5 and 12 years, with spastic diplegia, and without having major surgeries or botulinum toxin injection on lower extremities during the past 6 months prior to participate in this study.

Methods: The Vicon 250 motion analysis system, 3 AMTI force platforms and the EMG recording system will be used to collect data of sit-to-stand (STS) movements. Baseline, pre- and post-training evaluations will be carried out. The duration of the baseline and pre-training evaluations is 2 months. The training period will take about 6 weeks. Each evaluation will take two separate days to accomplish. On the first day, the STS1RM of individual children was determined. On the second day, kinematic and kinetic data of STS movements in natural and loaded (applying load of 50% STS1RM during STS movements) conditions were collected. Data of smoothness, maximal extension moment and around hip and knee joints, onset time of lower extremity muscles will then be calculated. Results of each evaluation will be used for further comparison.

  Eligibility

Ages Eligible for Study:   5 Years to 12 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Diagnosed as spastic diplegia
  • Aged between 5 and 12 years
  • Able to perform the STS movements without assistance
  • Able to cooperate and understand commands given

Exclusion Criteria:

  • Severe musculoskeletal deformity or pain on lower extremities
  • Botulism injection in the past 3 months or major operations in the preceding 6 months on lower extremities
  • Uncontrolled epilepsy
  • Major sensory deficits, such as blindness or deafness
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00314301

Contacts
Contact: Yuh-Ting Lin, MSc 866-2-8966-7000 ext 1411 yuh_ting_lin@hotmail.com
Contact: Jao-Shwann Liang, MD 866-2-8966-7000 ext 1411

Locations
Taiwan
National Taiwan University Hospital
Taipei, Taiwan, 100
Sponsors and Collaborators
Far Eastern Memorial Hospital
National Taiwan University
Investigators
Principal Investigator: Yuh-Ting Lin, MSc Research Ethics Review Committee of the Far Eastern Memorial Hospital
  More Information

Study ID Numbers: 94023
Study First Received: April 12, 2006
Last Updated: April 14, 2006
ClinicalTrials.gov Identifier: NCT00314301  
Health Authority: Taiwan: Department of Health

Keywords provided by Far Eastern Memorial Hospital:
cerebral palsy
resistance
movement
biomechanics

Study placed in the following topic categories:
Paralysis
Cerebral Palsy
Brain Damage, Chronic
Central Nervous System Diseases
Brain Diseases
Brain Injuries

Additional relevant MeSH terms:
Nervous System Diseases

ClinicalTrials.gov processed this record on January 16, 2009