| Topic: | Digestive Diseases (DD) |
| Title: | Nonsteroidal Anti-Inflammatory Drugs, Enterocolonic Ulceration, and Inflammatory Bowel Disease. |
| Author: | Smale, S.; Bjarnason, I. |
| Source: | In: Bayless, T.M. and Hanauer, S.B. Advanced Therapy of Inflammatory Bowel Disease. Hamilton, Ontario: B.C. Decker Inc. 2001. p. 625-629. |
| Availability: | Available from B.C. Decker Inc. 20 Hughson Street South, P.O. Box 620, L.C.D. 1 Hamilton, Ontario L8N 3K7. (905) 522-7017 or (800) 568-7281. Fax (905) 522-7839. Email: info@bcdecker.com. Website: www.bcdecker.com. PRICE: $129.00 plus shipping and handling. ISBN: 1550091220. |
| Abstract: | Nonsteroidal antiinflammatory drugs (NSAIDs) cause damage through the gastrointestinal tract. This chapter on NSAIDS, enterocolonic (small bowel) ulceration and inflammatory bowel disease (IBD) is from the second edition of a book devoted to the details of medical, surgical, and supportive management of patients with Crohn's disease (CD) and ulcerative colitis (UC), together known as IBD. The authors outline an approach to treatment of the damage of NSAIDs to the small bowel and the management of patients with IBD who require NSAIDs. The authors caution that the use of NSAIDs in patients with IBD is challenging because the drugs may cause relapse of disease. Specific issues addressed include iron deficiency anemia, hypoalbuminemia (reduced levels of protein in the blood), strictures (narrowing of the intestine), NSAID induced colon damage, and the use of NSAIDs in patients with IBD. Rarely, NSAIDs actually cause colitis, but their use is associated with an enhanced risk of appendicitis in the elderly and diverticular complications (fistulae and abscesses). 6 references. |
| Format: | Book Chapter |
| Language: | English. |
| Major Keywords: | Digestive System Diseases. Inflammatory Bowel Disease. Ulcerative Colitis. Crohns Disease. Patient Care Management. Complications. Antiinflammatory Agents. Drug Therapy. Drug Effects. |
| Minor Keywords: | Pathology. Symptoms. Risk Factors. Stricture. Anemia. Appendicitis. Diverticulosis. Diverticulitis. Fistula. Chronic Disease. Pain. Analgesics. |
| Publication Number: | DDBK08670 |
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