| Disease/Syndrome |
Carbon disulfide, chronic toxic effect |
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| Category |
Chronic Poison |
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| Acute/Chronic |
Chronic |
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| Biomedical References |
Search PubMed |
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| Comments |
Chronic heavy exposure to carbon disulfide causes a syndrome similar to chronic solvent encephalopathy with additional toxic effects to the eye and cardiovascular system. Finnish studies showed excess mortality from coronary artery disease in viscous rayon workers employed in the 1940s through the 1960s. Toxic effects were greatest in the 1940s when exposures averaged >60 ppm compared to average exposures of 20-60 ppm in the 1950s and 10-30 ppm in the 1960s. A Japanese study found evidence of retinopathy in 35% of workers exposed to concentrations above 20 ppm, 23% of those exposed to less than 20 ppm, and 4% of the controls. [ATSDR ToxProfiles] |
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| Latency/Incubation |
Years to decades |
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| Diagnostic |
Exposure history; Neuropsychological testing; Ophthalmological and cardiac examinations; |
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| ICD-9 Code |
982.2 |
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| Related Information in Haz-Map |
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| Symptoms/Findings |
Symptoms/Findings associated with this disease:
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| Job Tasks |
High risk job tasks associated with this disease:
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| Agents |
Hazardous agents that cause the occupational disease:
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