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Vomiting
- Onset: <10 minutes after exposure
- Percent of victims who vomit at this dose: 100%
Diarrhea
- Heavy
- Onset: within minutes to hour after exposure
- Percent of victims with diarrhea at this dose: ~100%
Headache
- Severe
- Onset: 1-2 hours after exposure
- Percent of victims with headache at this dose: 80-90%
Level of consciousness
- Loss of consciousness, may last seconds to minutes
- Onset: seconds-minutes after exposure
- Percent of victims with change in mental status at doses >50 Gy: 100%
Body temperature
- High fever
- Onset: < 1 hour after exposure
- Percent of victims with fever at this dose: 100%
Medical response
- Palliative treatment, especially for those with combined injury
- Aggressive supportive care in selected cases
- Palliative care for all others
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Duration
- Patients move rapidly from prodrome to manifest illness, with short if any latency in between.
Epilation
- Usually complete hair loss
Medical response
- Palliative treatment, especially for those with combined injury
- Aggressive supportive care in selected cases
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Onset
Duration
- Hours to months until recovery or death
Possible clinical effects
- Anorexia
- Fever
- Malaise, weakness
- Bleeding, infection
- Epilation: hair is lost by day 10
- Nausea, vomiting
- Diarrhea: common by day 4-5; severe, profuse, bloody
- Seizures, impaired level of consciousness
- Hypotension
Medical response
- Extremely aggressive supportive care for salvage in selected cases with good prognosis
- Palliative care for all others
- Psychological support
Lethality
- Uniformly fatal within 1-2 weeks without aggressive supportive care
- Palliative care for those unlikely to survive
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Recovery
- Not expected without the most aggressive supportive care
Time to Death
- Usually within hours to days of exposure
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