Magnetic Resonance (MR) Spectroscopy of Breast Cancer Tissue

This study is currently recruiting participants.

Verified by Norwegian University of Science and Technology, April 2008

Sponsors and Collaborators:	Norwegian University of Science and Technology The Research Council of Norway Norwegian Womens Public Health Association
Information provided by:	Norwegian University of Science and Technology
ClinicalTrials.gov Identifier:	NCT00184210

Purpose

Breast cancer tissue is collected from women undergoing scheduled surgery for breast cancer. The tissue specimen are analyzed by MR spectroscopy. After MR, the intact tissue specimen can be analyzed by other methods, as histopathology.

The MR spectral profiles are compared to clinical findings as the patients diagnosis, lymph node status and tumor size.

Condition
Breast Neoplasms

Genetics Home Reference related topics: breast cancer

MedlinePlus related topics: Breast Cancer Cancer

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cohort, Cross-Sectional
Official Title:	HR MAS MR Spectroscopy of Breast Cancer Tissue

Further study details as provided by Norwegian University of Science and Technology:

Biospecimen Retention: Samples With DNA

Biospecimen Description:

tissue

Estimated Enrollment:	1000
Study Start Date:	January 2000

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

women in surgery for breast cancer

Criteria

Inclusion Criteria:

Palpable breast cancer lesion

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00184210

Contacts

Contact: Beathe Sitter, PhD	+47 73 55 13 53	beathesi@ntnu.no
Contact: Tone F Bathen, PhD	+47 73 86 38 44	tone.bathen@ntnu.no

Locations

Norway
Norwegian University of Technology and Science	Recruiting
Trondheim, Norway, 7491
Contact: Beathe Sitter, PhD +47 73 55 13 53 beathesi@ntnu.no

Sponsors and Collaborators

Norwegian University of Science and Technology

The Research Council of Norway

Norwegian Womens Public Health Association

Investigators

Study Chair:

Ingrid S Gribbestad, PhD

Norwegian University of Technology and Science

More Information

Publications of Results:

Sitter B, Sonnewald U, Spraul M, Fjosne HE, Gribbestad IS. High-resolution magic angle spinning MRS of breast cancer tissue. NMR Biomed. 2002 Aug;15(5):327-37.

Sitter B, Lundgren S, Bathen TF, Halgunset J, Fjosne HE, Gribbestad IS. Comparison of HR MAS MR spectroscopic profiles of breast cancer tissue with clinical parameters. NMR Biomed. 2006 Feb;19(1):30-40.

Bathen TF, Jensen LR, Sitter B, Fjosne HE, Halgunset J, Axelson DE, Gribbestad IS, Lundgren S. MR-determined metabolic phenotype of breast cancer in prediction of lymphatic spread, grade, and hormone status. Breast Cancer Res Treat. 2006 Oct 24; [Epub ahead of print]

Responsible Party:	NTNU ( Norwegian University of Science and Technology )
Study ID Numbers:	154080/I30
Study First Received:	September 12, 2005
Last Updated:	April 18, 2008
ClinicalTrials.gov Identifier:	NCT00184210
Health Authority:	Norway: Norwegian Social Science Data Services

Keywords provided by Norwegian University of Science and Technology:

Magnetic Resonance Spectroscopy

Study placed in the following topic categories:

Skin Diseases
Breast Neoplasms
Breast Diseases

Additional relevant MeSH terms:

Neoplasms
Neoplasms by Site

ClinicalTrials.gov processed this record on January 14, 2009