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Brain Cancer Trial Results
1. Palliative Radiation Extends Survival for Elderly Patients with Glioblastoma
(Posted: 04/30/2007) - Elderly patients with glioblastoma benefit from palliative radiation therapy, which provides significantly increased survival with no detriment to quality of life, according to the April 12, 2007, New England Journal of Medicine.
2. Fluorescence-Guided Surgery Postpones Relapse in Patients with Malignant Glioma
(Posted: 05/30/2006) - Fluorescence-guided surgery delayed the progression of malignant glioma (a form of brain cancer) compared to conventional surgery, but didn't help patients live longer, according to the May 2006 issue of Lancet Oncology.
3. Adding Temozolomide (Temodar®) to Radiation Increases Survival in Glioblastoma Multiforme
(Posted: 06/07/2004, Updated: 12/05/2005) - Adding the drug temozolomide (Temodar®) to radiation therapy for the treatment of a brain tumor called glioblastoma multiforme increased survival in a large randomized trial conducted in Canada and Europe. While this approach has been customary in the United States for several years, these findings are definitive and should establish this approach as the standard of care.
4. Radiotherapy Immediately After Surgery Postpones Relapse, but not Death, in Patients With Low-Grade Gliomas
(Posted: 10/12/2005) - Patients treated with radiotherapy immediately following surgery for low-grade glioma (a form of brain cancer) lived about two years longer before relapse than patients treated with radiotherapy only after their disease had begun to progress. However, the early treatment didn't help patients live longer overall, according to the Sept. 17, 2005, issue of the Lancet.
5. Dexmethylphenidate Reduces Some Symptoms of Chemobrain
(Posted: 06/01/2005) - Cancer patients diagnosed with chemotherapy-related fatigue and cognitive impairment ("chemobrain") were helped by the drug dexmethylphenidate (Focalin®), according to findings presented at the 2005 meeting of the American Society of Clinical Oncology.
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