Agent Name |
Acetophenone |
CAS Number |
98-86-2 |
Formula |
C8-H8-O |
Major Category |
Other Classes |
Synonyms |
1-Phenyl-1-ethanone; 1-Phenylethanone; Acetofenon [Czech]; Acetophenon; Acetylbenzene; Acetylbenzol; Benzene, acetyl-; Benzoyl methide; Benzoylmethide; Ethanone, 1-phenyl-; Hypnone; Ketone, methyl phenyl; Methyl phenyl ketone; Phenyl methyl ketone; USAF EK-496; [ChemIDplus] UN 1993 |
Category |
Aromatic Ketones |
Description |
Liquid that forms crystals at low temperature; [Merck Index] |
Sources/Uses |
Used in textile coatings; [Olson, p. 543] Used in perfumes for orange blossom odor; Also used in organic synthesis and as a polymerization catalyst for olefins; [Merck Index] Used in the past as an analgesic and anesthetic; [ACGIH] Used as a solvent in plastics and resins and a flavoring agent in foods; [HSDB] |
Comments |
A skin and eye irritant; Can cause CNS depression at high concentrations; [Olson, p. 543] Inhalation of high concentration can cause unconsciousness; [ICSC] |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
TLV (ACGIH) |
10 ppm |
Vapor Pressure |
0.39 mm Hg |
Odor Threshold Low |
0.17 ppm |
Odor Threshold High |
0.6 ppm |
Lethal Concentration |
LC (rats) = >210 ppm/8h |
Explanatory Notes |
Odor Threshold avg = 0.5 ppm. [CHEMINFO] mp = 20.5 deg C; bp = 202 deg C; Flash point = 105 deg C; [Merck Index] |
Adverse Effects |
Neurotoxin |
CNS Solvent Syndrome |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: ACETOPHENONE
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