| Agent Name |
Tetrakis (hydroxymethyl) phosphonium chloride |
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| CAS Number |
124-64-1 |
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| Formula |
C4-H12-O4-P.Cl |
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| Major Category |
Other Classes |
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| Synonyms |
Phosphonium, tetrakis(hydroxymethyl)-, chloride; Pyroset TKC; Retardol C; THPC; Tetrahydroxymethylphosphonium chloride; Tetrakis(hydroxymethyl)phosphochloride; Tetrakis(hydroxymethyl)phosphonium chloride; Tetrakis-(hydroxymethyl)fosfoniumchlorid [Czech] ; Tetramethylolphosphonium chloride; [ChemIDplus] |
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| Category |
Phosphorus Compounds |
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| Description |
Crystalline solid; [ACGIH] Available commercially as an 80% aqueous solution; [MSDSonline] |
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| Sources/Uses |
Used to make crease-resistant and flame-retardant finishes for textiles, e.g., children's sleepwear; [ACGIH] Used as a disinfectant--effective against escherichia coli and staphylococcus aureus, and foot-and-mouth disease virus of cattle; [HSDB] |
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| Comments |
Degrades rapidly in the environment in the presence of moisture and sunlight; Tetrakis (hydroxymethyl) phosphonium sulfate (THPS) was a sensitizer in 14 of 20 guinea pigs; Tetrakis (hydroxymethyl) phosphonium chloride (THPC) was not a skin sensitizer in tests on human skin; Neither THPS or THPC inhibited acetylcholinesterase; Rats and mice given repeated high oral doses have liver damage; [ACGIH] Toxic if swallowed; May cause skin irritation and sensitization; May cause respiratory sensitization; [MSDSonline] See "Tetrakis (hydroxymethyl) phosphonium sulfate." |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
2 mg/m3 |
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| Vapor Pressure |
1.13 x 10 -07 mm Hg |
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| Explanatory Notes |
VP = 1 mm Hg @ 77 deg F; [CAMEO] |
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| Adverse Effects |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| IARC Carcinogen |
Not Classifiable |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: Tetrakis (hydroxymethyl) phosphonium salts
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