Vouchers vs. Prizes for Cocaine-Dependent Methadone Patients - 2 - Full Text View

Sponsors and Collaborators:	National Institute on Drug Abuse (NIDA) University of Connecticut Health Center
Information provided by:	National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier:	NCT00249535

Purpose

The purpose of this study is to compare voucher-based contingency management (CM) procedures to a lower-cost CM system that provides opportunities to win prizes. Cocaine-dependent outpatients are randomly assigned to (a) standard treatment, (b) standard treatment plus usual magnitude prize CM ($300), (c) standard treatment plus higher magnitude prize CM ($900), or (d) standard treatment plus voucher CM ($900). Urine and breath samples are collected 2-3x/week for 14 weeks. Follow-up interviews are conducted at 1,3,6 and 9 months following intake during which substance use and psychosocial functioning are assessed.

Condition	Intervention
Cocaine Dependence	Behavioral: Contingency management

Drug Information available for: Methadone Methadone hydrochloride 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))- Cocaine hydrochloride

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Open Label, Active Control, Single Group Assignment, Efficacy Study
Official Title:	Vouchers vs. Prizes for Cocaine-Dependent Methadone Patients

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:

Cocaine use [ Time Frame: baseline and each follow-up ] [ Designated as safety issue: No ]

Estimated Enrollment:	240
Study Start Date:	March 2005
Estimated Study Completion Date:	June 2009
Estimated Primary Completion Date:	June 2009 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
1: Experimental standard treatment plus usual magnitude prize CM ($300)	Behavioral: Contingency management Rewards valued $1-$100 for abstinence
2: Experimental standard treatment plus higher magnitude prize CM ($900)	Behavioral: Contingency management Rewards valued $1-$100 for abstinence
3: Experimental standard treatment plus voucher CM ($900)	Behavioral: Contingency management Rewards valued $1-$100 for abstinence

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion criteria:

age > 18 years
current DSM-IV diagnosis of cocaine dependence
received methadone treatment at the clinic for at least 3 months
on a stable dose of methadone (no changes in dosing) for at least one month and not presently requesting a dose alteration
submitted one or more clinic-collected cocaine positive urine samples in the previous 3 months
English speaking
pass a brief quiz related to understanding of the informed consent form

Exclusion criteria:

have a serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, bipolar disorder, severe or psychotic major depression, or suicide risk)
have dementia (<23 on the Mini Mental State Exam; Folstein et al. 1975)
are in recovery from pathological gambling

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00249535

Contacts

Contact: Ellen M Ciesielski, B.A.

(860)679-4556

ciesielski@psychiatry.uchc.edu

Locations

United States, Connecticut
UConn Health Center	Recruiting
Farmington, Connecticut, United States, 06030
Principal Investigator: Nancy M Petry, Ph.D.

Sponsors and Collaborators

National Institute on Drug Abuse (NIDA)

University of Connecticut Health Center

Investigators

Principal Investigator:

Nancy Petry, Ph.D.

University of Connecticut Health Center

More Information

Responsible Party:	UConn Health Center ( Nancy Petry, Ph.D. )
Study ID Numbers:	NIDA-13444-2, R01-13444-2
Study First Received:	November 3, 2005
Last Updated:	May 23, 2008
ClinicalTrials.gov Identifier:	NCT00249535
Health Authority:	United States: Federal Government; United States: Institutional Review Board

Keywords provided by National Institute on Drug Abuse (NIDA):

Substance Abuse
Contingency Management

Study placed in the following topic categories:

Cocaine-Related Disorders
Methadone
Mental Disorders

Substance-Related Disorders
Disorders of Environmental Origin
Cocaine

ClinicalTrials.gov processed this record on January 14, 2009