When: September 2004
Where: Nationwide
Institute: National Institute of Environmental Health Sciences (NIEHS)

Sisters share a lot more than secrets and laughter. They also share genes and at least some elements of lifestyle. Scientists already know that if a woman has breast cancer, her sister has a much higher chance of developing the disease, too. That’s why the NIEHS is kicking off the Sister Study, which hopes to glean more information about environmental and genetic causes of breast cancer. Researchers believe ingredients in many common products interfere in the role of hormones, possibly contributing to breast cancer development. But studies have not been able to establish a strong link.

In October, NIEHS will begin recruiting 50,000 women nationwide who do not have breast cancer, but have a sister who has been diagnosed with the disease. The Sister Study will follow women for at least 10 years, providing data that researchers will use to search for causes of breast cancer. Researchers will gather information about women's lifestyles, medical histories, jobs, and environment, as well as collect blood and urine samples, toenail clippings and house dust. The women will answer questions about their diet, family history, environmental exposures, and additional information if they develop breast cancer.

To be eligible for the study, women must be between 35 and 74 years of age, live in the United States, and have a sister related by blood who has been diagnosed with breast cancer. Women who live in Arizona, Florida, Illinois, Missouri, North Carolina, Ohio, Rhode Island, and Virginia can enroll now. Women in other states can pre-register now for enrollment in mid-October. Women who do not qualify can still help by volunteering or by spreading the word about the study.

Next Steps
For information or to join, call toll-free (877) 474-7837 or visit www.sisterstudy.org.

^ TOP OF PAGE