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Sponsored by: |
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
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Information provided by: | National Institutes of Health Clinical Center (CC) |
ClinicalTrials.gov Identifier: | NCT00001979 |
Kidney diseases related to the immune system include, nephrotic syndrome, glomerulonephritis, membranous nephropathy, lupus nephritis, and nephritis associated with connective tissue disorders.
This study will allow researchers to admit and follow patients suffering from autoimmune diseases of the kidney. It will attempt to provide information about the causes and specific abnormalities associated with autoimmune kidney disease.
Patients with kidney disease as a result of their immune system, and patients with diseases of the immune system who may later develop kidney disease, will be potential subjects for this study.
Patients will undergo a history and physical examination, and standard laboratory test to more closely understand the causes, signs, symptoms, and responses to medication of these diseases. Based on these evaluations the patients may qualify as candidates for other experimental studies. At any time these patients may be asked to submit blood or urine samples for further research.
Condition |
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Glomerulonephritis Lupus Nephritis Membranous Glomerulonephritis Nephritis Nephrotic Syndrome |
Study Type: | Observational |
Official Title: | Studies of Immunologically-Mediated Kidney Diseases |
Study Start Date: | April 1992 |
Patients with known or suspected immunologically-mediated kidney diseases, including but not limited to, nephrotic syndrome, glomerulonephritis, membranous nephropathy, lupus nephritis, and nephritis associated with other systemic or connective tissue disorders, will be evaluated at the Clinical Center. Patients who have immunologically-mediated diseases with the potential for kidney disease will be evaluated as well. Studies will include characterization of the clinical and laboratory features of these disorders, studies of natural history and complications, evaluation of responses to standard treatment, and determination of the patients' eligibility to enter other experimental diagnostic or therapeutic protocols. Patients may be asked to contribute blood and/or urine samples for immunological research studies.
Ages Eligible for Study: | 5 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Immunologically-mediated renal diseases, proven or suspected.
Immunologically-mediated diseases with potential for kidney disease.
Willingness of the patient or guardian to give informed consent.
EXCLUSION CRITERIA:
Concomitant medical problems which would confound the interpretation of studies of the immunologic kidney disorder.
Concomitant medical, surgical or other conditions for which inadequate facilities or funds are available to support their care at the NIH.
Contact: Patient Recruitment and Public Liaison Office | (800) 411-1222 | prpl@mail.cc.nih.gov |
Contact: TTY | 1-866-411-1010 |
United States, Maryland | |
National Institutes of Health Clinical Center, 9000 Rockville Pike | Recruiting |
Bethesda, Maryland, United States, 20892 |
Study ID Numbers: | 920156, 92-DK-0156 |
Study First Received: | January 20, 2000 |
Last Updated: | December 23, 2008 |
ClinicalTrials.gov Identifier: | NCT00001979 |
Health Authority: | United States: Federal Government |
Glomerulonephritis Nephropathy Lupus Nephritis Nephrotic Syndrome |
Nephrosis Glomerulonephritis Autoimmune Diseases Lupus Erythematosus, Systemic Urologic Diseases Lupus Nephritis |
Nephritis Connective Tissue Diseases Glomerulonephritis, Membranous Kidney Diseases Membranous nephropathy, idiopathic Nephrotic Syndrome |
Pathologic Processes Disease Immune System Diseases Syndrome |