Methamphetamine Abuse Treatment in Patients With AIDS - 1

This study has been completed.

Sponsors and Collaborators:	National Institute on Drug Abuse (NIDA) Friends Research Institute, Inc.
Information provided by:	National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier:	NCT00000321

Purpose

The purpose of this study is to evaluate the efficacy of desipramine, sertraline, and placebo on methamphetamine dependent gay men with AIDS.

Condition	Intervention	Phase
Substance-Related Disorders	Drug: Desipramine	Phase IV

MedlinePlus related topics: Methamphetamine

Drug Information available for: Desipramine Desipramine hydrochloride Amphetamine Methamphetamine

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment
Official Title:	Methamphetamine Abuse Pharmacology in Patients With AIDS

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:

Craving
Retention
Depression
Methamphetamine use
Anxiety and Depression
ASI Scales (7)
AIDS medical care engagement
High risk sexual behaviors
Mood indicators

Estimated Enrollment:	0
Study Start Date:	October 1996
Estimated Study Completion Date:	December 2001

Eligibility

Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	No

Criteria

Please contact site for information.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000321

Locations

United States, California
Friends Research Institute
Los Angeles, California, United States, 90025

Sponsors and Collaborators

National Institute on Drug Abuse (NIDA)

Friends Research Institute, Inc.

Investigators

Principal Investigator:

Frank Gawin, M.D.

Friends Research Institute, Inc.

More Information

Study ID Numbers:	NIDA-10643-1, R01-10643-1
Study First Received:	September 20, 1999
Last Updated:	August 16, 2005
ClinicalTrials.gov Identifier:	NCT00000321
Health Authority:	United States: Federal Government

Study placed in the following topic categories:

Methamphetamine
Dopamine
Mental Disorders
Substance-Related Disorders

Disorders of Environmental Origin
Amphetamine
Desipramine

Additional relevant MeSH terms:

Dopamine Uptake Inhibitors
Neurotransmitter Agents
Neurotransmitter Uptake Inhibitors
Molecular Mechanisms of Pharmacological Action
Adrenergic Agents
Sympathomimetics
Adrenergic Uptake Inhibitors
Physiological Effects of Drugs
Psychotropic Drugs
Central Nervous System Stimulants

Enzyme Inhibitors
Pharmacologic Actions
Antidepressive Agents, Tricyclic
Autonomic Agents
Therapeutic Uses
Dopamine Agents
Peripheral Nervous System Agents
Central Nervous System Agents
Antidepressive Agents

ClinicalTrials.gov processed this record on January 15, 2009