Effect of Nutrition on Muscle Protein Synthesis

This study is not yet open for participant recruitment.

Verified by Maastricht University Medical Center, March 2008

Sponsored by:	Maastricht University Medical Center
Information provided by:	Maastricht University Medical Center
ClinicalTrials.gov Identifier:	NCT00604929

Purpose

The present proposal is designed to examine the effect of carbohydrate and protein co-ingestion on muscle protein synthesis during endurance type exercise activities. We hypothesize that muscle protein synthesis is higher when protein is co-ingested during exercise.

Condition	Intervention
Healthy	Dietary Supplement: carbohydrate and protein

MedlinePlus related topics: Exercise and Physical Fitness

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Basic Science, Randomized, Double Blind (Subject, Investigator), Placebo Control, Crossover Assignment
Official Title:	The Effect of Carbohydrate and Protein Intake on Muscle Protein Synthesis During Endurance Exercise

Further study details as provided by Maastricht University Medical Center:

Primary Outcome Measures:

Differences in muscle protein synthesis rates between carbohydrate and carbohydrate + protein. [ Time Frame: 1 day ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

Difference in whole-body protein synthesis and breakdown between carbohydrate and carbohydrate plus protein. [ Time Frame: 1 day ] [ Designated as safety issue: No ]

Estimated Enrollment:	12
Study Start Date:	March 2008
Estimated Primary Completion Date:	July 2008 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
1: Experimental	Dietary Supplement: carbohydrate and protein The intake of carbohydrate and protein during endurance type exercise

Eligibility

Ages Eligible for Study:	18 Years to 28 Years
Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

recreationally endurance trained

Exclusion Criteria:

BMI > 25 kg/m2
Not physically active

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00604929

Contacts

Contact: M Beelen, MSc		milou.beelen@BW.unimaas.nl
Contact: LJC van loon, PhD		L.vanLoon@HB.unimaas.nl

Sponsors and Collaborators

Maastricht University Medical Center

Investigators

Principal Investigator:

L van Loon, PhD

Maastricht University Medical Center

More Information

Responsible Party:	Maastricht university ( L.J.C. van Loon, PhD )
Study ID Numbers:	MEC 0000
Study First Received:	January 17, 2008
Last Updated:	March 31, 2008
ClinicalTrials.gov Identifier:	NCT00604929
Health Authority:	Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)

Keywords provided by Maastricht University Medical Center:

muscle protein synthesis
whole-body protein breakdown
nutrition

Study placed in the following topic categories:

Healthy

ClinicalTrials.gov processed this record on January 14, 2009