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Sponsored by: |
Federal University of São Paulo |
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Information provided by: | Federal University of São Paulo |
ClinicalTrials.gov Identifier: | NCT00291863 |
This study will analyse the effect of simvastatin on endothelium dependent venodilation in chronic renal failure patients treated by peritoneal dialysis. The hypothesis is that patients will have a greater endothelium dependent venodilation after four months of simvastatin use.
Condition | Intervention | Phase |
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Renal Failure, End Stage Peritoneal Dialysis |
Drug: Simvastatin |
Phase IV |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study |
Official Title: | Simvastatin Effect on Endothelium Dependent Venodilation in Chronic Renal Failure Patients Treated by Peritoneal Dialysis |
Estimated Enrollment: | 30 |
Study Start Date: | February 2006 |
Estimated Study Completion Date: | February 2006 |
This study will analyse the effect of simvastatin on endothelium dependent venodilation in chronic renal failure patients treated by peritoneal dialysis. The hypothesis is that patients will have a greater endothelium dependent venodilation after four months of simvastatin use.
Ages Eligible for Study: | 18 Years to 80 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contact: Maristela Bohlke, MD | 55 53 32264098 | mbohlke@conesul.com.br |
Brazil, Rio Grande do Sul | |
São Lucas Hospital | Recruiting |
Porto Alegre, Rio Grande do Sul, Brazil | |
Principal Investigator: Carlos Eduardo P Figueiredo, PhD |
Principal Investigator: | Maristela Bohlke, master | Federal University of São Paulo |
Study ID Numbers: | 0089/04 |
Study First Received: | February 14, 2006 |
Last Updated: | February 15, 2006 |
ClinicalTrials.gov Identifier: | NCT00291863 |
Health Authority: | Brazil: Ministry of Health |
end stage renal failure peritoneal dialysis simvastatin endothelium vasodilation |
Renal Insufficiency Urologic Diseases Simvastatin Renal Insufficiency, Chronic |
Kidney Failure, Chronic Kidney Diseases Kidney Failure |
Antimetabolites Molecular Mechanisms of Pharmacological Action Therapeutic Uses Antilipemic Agents |
Enzyme Inhibitors Anticholesteremic Agents Hydroxymethylglutaryl-CoA Reductase Inhibitors Pharmacologic Actions |